Class information for:
Level 1: PIRFENIDONE//FLUOROFENIDONE//STATE MED GENET CHINA

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
28477 206 36.1 83%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
501 3       SYSTEMIC SCLEROSIS//SCLERODERMA//IDIOPATHIC PULMONARY FIBROSIS 22108
968 2             IDIOPATHIC PULMONARY FIBROSIS//INTERSTITIAL LUNG DISEASE//PULMONARY FIBROSIS 10678
28477 1                   PIRFENIDONE//FLUOROFENIDONE//STATE MED GENET CHINA 206

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PIRFENIDONE authKW 4657374 40% 38% 82
2 FLUOROFENIDONE authKW 1709002 7% 82% 14
3 STATE MED GENET CHINA address 758917 8% 32% 16
4 AKF PD authKW 592921 2% 100% 4
5 2 2 DIMETHYL 3 4 DIHYDRO 2H PYRROLE N OXIDE DMPO authKW 148230 0% 100% 1
6 21H PYRIDONE DERIVATIVES authKW 148230 0% 100% 1
7 5 CARBOXYPIRFENIDONE authKW 148230 0% 100% 1
8 5 HYDROXYPIRFENIDONE authKW 148230 0% 100% 1
9 ANTI FIBROTIC AGENT ADHESIONS PERITONEAL authKW 148230 0% 100% 1
10 ARTMENT VET SURG RADIOL address 148230 0% 100% 1

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Pharmacology & Pharmacy 578 32% 0% 66
2 Transplantation 338 9% 0% 18
3 Urology & Nephrology 200 10% 0% 20
4 Respiratory System 101 6% 0% 13
5 Immunology 81 11% 0% 23
6 Surgery 47 10% 0% 21
7 Biochemical Research Methods 36 5% 0% 11
8 Ophthalmology 30 4% 0% 8
9 Toxicology 30 4% 0% 9
10 Physiology 26 5% 0% 10

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 STATE MED GENET CHINA 758917 8% 32% 16
2 ARTMENT VET SURG RADIOL 148230 0% 100% 1
3 CHANGSHA CENT HOSP 148230 0% 100% 1
4 FARM BIOMED IBUBNUCL UNIV PEDRALBES 148230 0% 100% 1
5 ORAL MAXILLO IAL SURGSHANGHAI ST 148230 0% 100% 1
6 PHARMACY UNION HOSP 148230 0% 100% 1
7 STATE OPHTHALMOL GLAUCOMA 148230 0% 100% 1
8 SURG KIDNEY SHINJUKU KU 148230 0% 100% 1
9 UNITAT FARCAL FARMACOGNOSIA 148230 0% 100% 1
10 VET AFFAIRS SAN DIEGO HEALTHCARE SYST MED 148230 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PULMONARY PHARMACOLOGY & THERAPEUTICS 1601 2% 0% 4
2 NEPHROLOGY 1090 2% 0% 4
3 PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY 722 1% 0% 2
4 RESEARCH COMMUNICATIONS IN MOLECULAR PATHOLOGY AND PHARMACOLOGY 710 1% 0% 2
5 BIOPHARMACEUTICS & DRUG DISPOSITION 688 1% 0% 3
6 NATURE REVIEWS DRUG DISCOVERY 629 1% 0% 2
7 MULTIPLE SCLEROSIS JOURNAL 565 1% 0% 3
8 INTERNATIONAL IMMUNOPHARMACOLOGY 543 2% 0% 4
9 DRUG DESIGN DEVELOPMENT AND THERAPY 424 1% 0% 2
10 MOLECULAR VISION 401 1% 0% 3

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 PIRFENIDONE 4657374 40% 38% 82 Search PIRFENIDONE Search PIRFENIDONE
2 FLUOROFENIDONE 1709002 7% 82% 14 Search FLUOROFENIDONE Search FLUOROFENIDONE
3 AKF PD 592921 2% 100% 4 Search AKF+PD Search AKF+PD
4 2 2 DIMETHYL 3 4 DIHYDRO 2H PYRROLE N OXIDE DMPO 148230 0% 100% 1 Search 2+2+DIMETHYL+3+4+DIHYDRO+2H+PYRROLE+N+OXIDE+DMPO Search 2+2+DIMETHYL+3+4+DIHYDRO+2H+PYRROLE+N+OXIDE+DMPO
5 21H PYRIDONE DERIVATIVES 148230 0% 100% 1 Search 21H+PYRIDONE+DERIVATIVES Search 21H+PYRIDONE+DERIVATIVES
6 5 CARBOXYPIRFENIDONE 148230 0% 100% 1 Search 5+CARBOXYPIRFENIDONE Search 5+CARBOXYPIRFENIDONE
7 5 HYDROXYPIRFENIDONE 148230 0% 100% 1 Search 5+HYDROXYPIRFENIDONE Search 5+HYDROXYPIRFENIDONE
8 ANTI FIBROTIC AGENT ADHESIONS PERITONEAL 148230 0% 100% 1 Search ANTI+FIBROTIC+AGENT+ADHESIONS+PERITONEAL Search ANTI+FIBROTIC+AGENT+ADHESIONS+PERITONEAL
9 CALU 3 CELL MONOLAYERS 148230 0% 100% 1 Search CALU+3+CELL+MONOLAYERS Search CALU+3+CELL+MONOLAYERS
10 FIBROBLASTIC RETICULAR CELL NETWORK 148230 0% 100% 1 Search FIBROBLASTIC+RETICULAR+CELL+NETWORK Search FIBROBLASTIC+RETICULAR+CELL+NETWORK

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 BRAIM, AEP , MACDONALD, MH , BRUSS, ML , STANLEY, SD , GIRI, JK , GIRI, SN , (2008) PHARMACOKINETICS AND CLINICAL EFFECTS OF PIRFENIDONE ADMINISTERED INTRAVENOUSLY IN HORSES.AMERICAN JOURNAL OF VETERINARY RESEARCH. VOL. 69. ISSUE 7. P. 952-960 27 66% 2
2 LASKY, J , (2004) PIRFENIDONE INTERMUNE/SHIONOGI/MARNAC.IDRUGS. VOL. 7. ISSUE 2. P. 166-172 24 75% 22
3 SHI, SJ , WU, JH , WU, J , ZENG, FD , (2009) DEVELOPMENT AND VALIDATION OF AN IMPROVED LC METHOD FOR THE SIMULTANEOUS DETERMINATION OF PIRFENIDONE AND ITS CARBOXYLIC ACID METABOLITE IN HUMAN PLASMA.CHROMATOGRAPHIA. VOL. 69. ISSUE 5-6. P. 459 -463 18 82% 2
4 WANG, YS , ZHAO, XP , ZHONG, J , CHEN, Y , LIU, XQ , WANG, GJ , (2006) SIMPLE DETERMINATION OF PIRFENIDONE IN RAT PLASMA VIA HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY.BIOMEDICAL CHROMATOGRAPHY. VOL. 20. ISSUE 12. P. 1375-1379 15 100% 10
5 TONG, SH , WANG, XQ , JIANG, HY , XU, XG , PAN, YB , CHEN, KM , WU, J , XU, QQ , DENG, J , HU, GX , (2010) DETERMINATION OF PIRFENIDONE IN RAT PLASMA BY LC-MS-MS AND ITS APPLICATION TO A PHARMACOKINETIC STUDY.CHROMATOGRAPHIA. VOL. 71. ISSUE 7-8. P. 709 -713 15 88% 3
6 MAHER, TM , (2010) PIRFENIDONE IN IDIOPATHIC PULMONARY FIBROSIS.DRUGS OF TODAY. VOL. 46. ISSUE 7. P. 473-482 24 50% 27
7 DOSANJH, A , (2007) PIRFENIDONE: A NOVEL POTENTIAL THERAPEUTIC AGENT IN THE MANAGEMENT OF CHRONIC ALLOGRAFT REJECTION.TRANSPLANTATION PROCEEDINGS. VOL. 39. ISSUE 7. P. 2153-2156 18 75% 7
8 BRAIM, AEP , MACDONALD, MH , BRUSS, ML , GRATTENDICK, KJ , GIRI, SN , MARGOLIN, SB , (2009) EFFECTS OF INTRAVENOUS ADMINISTRATION OF PIRFENIDONE ON HORSES WITH EXPERIMENTALLY INDUCED ENDOTOXEMIA.AMERICAN JOURNAL OF VETERINARY RESEARCH. VOL. 70. ISSUE 8. P. 1031-1042 25 47% 8
9 THORAT, SG , CHIKHALE, RV , (2016) DETERMINATION AND PHARMACOKINETIC STUDY OF PIRFENIDONE IN RAT SERUM BY HIGH-PERFORMANCE THIN-LAYER CHROMATOGRAPHY.JOURNAL OF CHROMATOGRAPHIC SCIENCE. VOL. 54. ISSUE 7. P. 1115 -1119 9 90% 0
10 CARTER, NJ , (2011) PIRFENIDONE IN IDIOPATHIC PULMONARY FIBROSIS.DRUGS. VOL. 71. ISSUE 13. P. 1721 -1732 13 59% 33

Classes with closest relation at Level 1


Rank Class id link
1 783 IDIOPATHIC PULMONARY FIBROSIS//USUAL INTERSTITIAL PNEUMONIA//IDIOPATHIC INTERSTITIAL PNEUMONIA
2 24934 HSP47//HEAT SHOCK PROTEIN 47//UMB GREENEBAUM CANC
3 7530 BLEOMYCIN//PULMONARY FIBROSIS//LUNG FIBROSIS
4 6047 UNILATERAL URETERAL OBSTRUCTION//OBSTRUCTIVE NEPHROPATHY//RENAL FIBROSIS
5 35950 CCL18//CC CHEMOKINE LIGAND 18//NIR1
6 28129 TRANILAST//2 2 PHENOXYACETAMIDOBENZAMIDES//2 2E 3 PHENYLPROP 2 ENOYLAMINOBENZAMIDES
7 8946 MESANGIAL CELLS//THY 1 NEPHRITIS//NEPHROL OSTEOL
8 16260 HERMANSKY PUDLAK SYNDROME//DYSBINDIN//DTNBP1
9 610 HEPATIC STELLATE CELLS//LIVER FIBROSIS//HEPATIC FIBROSIS
10 20077 DIABETIC NEPHROPATHY//URINE CYTOKINES CHEMOKINES//TNF SYSTEM

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