Class information for:
Level 1: DEXMEDETOMIDINE//CLONIDINE//ALPHA2 ADRENOCEPTOR AGONIST

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
2793 2147 32.2 79%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
8 4 CARDIAC & CARDIOVASCULAR SYSTEM//PERIPHERAL VASCULAR DISEASES//CARDIOL 1276458
57 3       ANGIOTENSIN II//HYPERTENSION//PERIPHERAL VASCULAR DISEASES 89232
1516 2             DEXMEDETOMIDINE//AGMATINE//IMIDAZOLINE RECEPTORS 7504
2793 1                   DEXMEDETOMIDINE//CLONIDINE//ALPHA2 ADRENOCEPTOR AGONIST 2147

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 DEXMEDETOMIDINE authKW 6781027 37% 60% 791
2 CLONIDINE authKW 333818 10% 11% 208
3 ALPHA2 ADRENOCEPTOR AGONIST authKW 212103 2% 45% 33
4 ALPHA2 AGONIST authKW 199440 2% 32% 44
5 SYMPATHETIC NERVOUS SYSTEM ALPHA2 ADRENERGIC AGONISTS CLONIDINE authKW 195695 1% 81% 17
6 PHARMACOLOGY CLONIDINE authKW 171229 1% 71% 17
7 SEDATION authKW 154918 8% 6% 172
8 ANESTHESIOLOGY WoSSC 149999 50% 1% 1074
9 SYMPATHETIC NERVOUS SYSTEM DEXMEDETOMIDINE authKW 129276 0% 91% 10
10 SYMPATHETIC NERVOUS SYSTEM CLONIDINE authKW 111056 1% 46% 17

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Anesthesiology 149999 50% 1% 1074
2 Critical Care Medicine 1710 6% 0% 125
3 Pharmacology & Pharmacy 1255 16% 0% 349
4 Pediatrics 559 7% 0% 140
5 Medicine, Research & Experimental 234 5% 0% 109
6 Neurosciences 210 8% 0% 180
7 Clinical Neurology 144 5% 0% 111
8 Medicine, General & Internal 100 5% 0% 106
9 Surgery 79 6% 0% 121
10 Cardiac & Cardiovascular System 65 4% 0% 76

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ANESTHESIOL 72378 26% 1% 558
2 ANESTHESIOL REANIMAT 29121 3% 3% 60
3 ANAESTHESIA INTENS PAIN CARE 28441 0% 100% 2
4 CARDIAC INTENS CAREMED 28441 0% 100% 2
5 IFR 124 28441 0% 100% 2
6 ANESTHESIOL PAIN MED 21108 4% 2% 77
7 ANAESTHESIA OPERAT 18959 0% 67% 2
8 ANESTHESIOL USCITAT INTENS CARE MED CLIN 15994 0% 38% 3
9 AGIZ DIS CENE HASTALIKLARI CERRAHISI ANABILIM DAL 14221 0% 100% 1
10 ANAESTHESIA ICU PAIN 14221 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ANESTHESIA AND ANALGESIA 48854 10% 2% 224
2 ANESTHESIOLOGY 40917 8% 2% 180
3 PEDIATRIC ANESTHESIA 34113 3% 3% 71
4 JOURNAL OF ANESTHESIA 18381 2% 3% 43
5 JOURNAL OF CLINICAL ANESTHESIA 17324 3% 2% 56
6 BRITISH JOURNAL OF ANAESTHESIA 11012 4% 1% 84
7 ACTA ANAESTHESIOLOGICA SCANDINAVICA 9082 3% 1% 66
8 EUROPEAN JOURNAL OF ANAESTHESIOLOGY 7872 2% 1% 41
9 JOURNAL OF NEUROSURGICAL ANESTHESIOLOGY 6933 1% 2% 23
10 PEDIATRIC CRITICAL CARE MEDICINE 4449 1% 1% 22

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 DEXMEDETOMIDINE 6781027 37% 60% 791 Search DEXMEDETOMIDINE Search DEXMEDETOMIDINE
2 CLONIDINE 333818 10% 11% 208 Search CLONIDINE Search CLONIDINE
3 ALPHA2 ADRENOCEPTOR AGONIST 212103 2% 45% 33 Search ALPHA2+ADRENOCEPTOR+AGONIST Search ALPHA2+ADRENOCEPTOR+AGONIST
4 ALPHA2 AGONIST 199440 2% 32% 44 Search ALPHA2+AGONIST Search ALPHA2+AGONIST
5 SYMPATHETIC NERVOUS SYSTEM ALPHA2 ADRENERGIC AGONISTS CLONIDINE 195695 1% 81% 17 Search SYMPATHETIC+NERVOUS+SYSTEM+ALPHA2+ADRENERGIC+AGONISTS+CLONIDINE Search SYMPATHETIC+NERVOUS+SYSTEM+ALPHA2+ADRENERGIC+AGONISTS+CLONIDINE
6 PHARMACOLOGY CLONIDINE 171229 1% 71% 17 Search PHARMACOLOGY+CLONIDINE Search PHARMACOLOGY+CLONIDINE
7 SEDATION 154918 8% 6% 172 Search SEDATION Search SEDATION
8 SYMPATHETIC NERVOUS SYSTEM DEXMEDETOMIDINE 129276 0% 91% 10 Search SYMPATHETIC+NERVOUS+SYSTEM+DEXMEDETOMIDINE Search SYMPATHETIC+NERVOUS+SYSTEM+DEXMEDETOMIDINE
9 SYMPATHETIC NERVOUS SYSTEM CLONIDINE 111056 1% 46% 17 Search SYMPATHETIC+NERVOUS+SYSTEM+CLONIDINE Search SYMPATHETIC+NERVOUS+SYSTEM+CLONIDINE
10 ALPHA2 ADRENERGIC AGONIST 110246 1% 29% 27 Search ALPHA2+ADRENERGIC+AGONIST Search ALPHA2+ADRENERGIC+AGONIST

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 MASON, KP , LERMAN, J , (2011) DEXMEDETOMIDINE IN CHILDREN: CURRENT KNOWLEDGE AND FUTURE APPLICATIONS.ANESTHESIA AND ANALGESIA. VOL. 113. ISSUE 5. P. 1129-1142 101 77% 55
2 MAHMOUD, M , MASON, KP , (2015) DEXMEDETOMIDINE: REVIEW, UPDATE, AND FUTURE CONSIDERATIONS OF PAEDIATRIC PERIOPERATIVE AND PERIPROCEDURAL APPLICATIONS AND LIMITATIONS.BRITISH JOURNAL OF ANAESTHESIA. VOL. 115. ISSUE 2. P. 171 -182 85 75% 16
3 TOBIAS, JD , (2007) DEXMEDETOMIDINE: APPLICATIONS IN PEDIATRIC CRITICAL CARE AND PEDIATRIC ANESTHESIOLOGY.PEDIATRIC CRITICAL CARE MEDICINE. VOL. 8. ISSUE 2. P. 115-131 85 88% 89
4 LI, AW , YUEN, VMY , GOULAY-DUFAY, S , KWOK, PCL , (2016) PHARMACOKINETICS AND PHARMACODYNAMICS OF DEXMEDETOMIDINE.DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY. VOL. 42. ISSUE 12. P. 1917 -1927 73 92% 0
5 WIJEYSUNDERA, DN , BENDER, JS , BEATTIE, WS , (2009) ALPHA-2 ADRENERGIC AGONISTS FOR THE PREVENTION OF CARDIAC COMPLICATIONS AMONG PATIENTS UNDERGOING SURGERY.COCHRANE DATABASE OF SYSTEMATIC REVIEWS. VOL. . ISSUE 4. P. - 110 65% 17
6 FARAG, E , ARGALIOUS, M , ABD-ELSAYED, A , EBRAHIM, Z , DOYLE, DJ , (2012) THE USE OF DEXMEDETOMIDINE IN ANESTHESIA AND INTENSIVE CARE: A REVIEW.CURRENT PHARMACEUTICAL DESIGN. VOL. 18. ISSUE 38. P. 6257-6265 80 78% 19
7 TOBIAS, JD , GUPTA, P , NAGUIB, A , YATES, AR , (2011) DEXMEDETOMIDINE: APPLICATIONS FOR THE PEDIATRIC PATIENT WITH CONGENITAL HEART DISEASE.PEDIATRIC CARDIOLOGY. VOL. 32. ISSUE 8. P. 1075-1087 73 82% 21
8 CHAN, AKM , CHEUNG, CW , CHONG, YK , (2010) ALPHA-2 AGONISTS IN ACUTE PAIN MANAGEMENT.EXPERT OPINION ON PHARMACOTHERAPY. VOL. 11. ISSUE 17. P. 2849 -2868 82 73% 31
9 EISENACH, JC , DEKOCK, M , KLIMSCHA, W , (1996) ALPHA(2)-ADRENERGIC AGONISTS FOR REGIONAL ANESTHESIA - A CLINICAL REVIEW OF CLONIDINE (1984-1995).ANESTHESIOLOGY. VOL. 85. ISSUE 3. P. 655-674 85 70% 366
10 ANGER, KE , (2013) DEXMEDETOMIDINE: A REVIEW OF ITS USE FOR THE MANAGEMENT OF PAIN, AGITATION, AND DELIRIUM IN THE INTENSIVE CARE UNIT.CURRENT PHARMACEUTICAL DESIGN. VOL. 19. ISSUE 22. P. 4003-4013 76 64% 8

Classes with closest relation at Level 1


Rank Class id link
1 34070 TETRAHYDROZOLINE//CLONIDINE TOXICITY//ABT ANASTHESIE PRIOPERAT INTENS MED
2 9490 ALPHA2 ADRENOCEPTOR SUBTYPES//ALPHA2C ADRENOCEPTOR//ALPHA2A ADRENOCEPTOR
3 7747 SEDATION//PROPOFOL INFUSION SYNDROME//PROPOFOL
4 15714 ARTERIAL PRESSURE RELATED NEURON//NOCICEPTION RELATED NEURON//NUCLEUS RETICULARIS GIGANTOCELLULARIS
5 3178 MEDETOMIDINE//XYLAZINE//ATIPAMEZOLE
6 28663 INTRATHECAL MIDAZOLAM//MIDAZOLAM//A DELTA FIBER EVOKED RESPONSE
7 4253 PROCEDURAL SEDATION//SEDATION//CHLORAL HYDRATE
8 9597 CAUDAL//CAUDAL BLOCK//PEDIATRIC ANESTHESIA
9 35963 CUTANEOUS ANALGESIA//INFILTRATIVE CUTANEOUS ANALGESIA//SPINAL BLOCKADE
10 15565 NEOSTIGMINE//CHOLINESTERASE INHIBITORS NEOSTIGMINE//CEREBROSPINAL FLUID COMPONENTS ACETYLCHOLINE NOREPINEPHRINE

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