Class information for:
Level 1: OREXIN//HYPOCRETIN//OREXIN A

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
2754 2157 51.6 90%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
11 4 NEUROSCIENCES//CLINICAL NEUROLOGY//NEUROL 1112395
133 3       MELATONIN//SLEEP//JOURNAL OF PINEAL RESEARCH 66554
1753 2             OREXIN//GALANIN//HYPOCRETIN 6481
2754 1                   OREXIN//HYPOCRETIN//OREXIN A 2157

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 OREXIN authKW 7193049 36% 65% 778
2 HYPOCRETIN authKW 3548480 19% 62% 404
3 OREXIN A authKW 2656286 11% 82% 228
4 OREXIN RECEPTORS authKW 992555 4% 89% 79
5 SB 334867 authKW 868406 3% 93% 66
6 OREXIN 1 RECEPTOR authKW 496860 2% 95% 37
7 OREXIN RECEPTOR ANTAGONIST authKW 428172 2% 92% 33
8 MOL NEUROSCI INTEGRAT PHYSIOL address 421815 2% 65% 46
9 OREXIN B authKW 414118 1% 91% 32
10 ALMOREXANT authKW 368524 1% 96% 27

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Neurosciences 17721 52% 0% 1132
2 Endocrinology & Metabolism 3376 16% 0% 348
3 Physiology 2138 12% 0% 251
4 Behavioral Sciences 1406 6% 0% 133
5 Pharmacology & Pharmacy 1336 17% 0% 359
6 Clinical Neurology 377 7% 0% 157
7 Psychiatry 311 5% 0% 117
8 Chemistry, Medicinal 212 4% 0% 80
9 Psychology, Biological 162 1% 0% 24
10 Biochemistry & Molecular Biology 102 11% 0% 229

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MOL NEUROSCI INTEGRAT PHYSIOL 421815 2% 65% 46
2 NARCOLEPSY 150351 2% 25% 42
3 DEP S CIRCADIAN DISORDERS 43341 0% 44% 7
4 YANAGISAWA ORPHAN RECEPTOR PROJECT 42879 0% 30% 10
5 EXPLORATORY ADV TECHNOL YANAGISAWA ORPHAN PRO 42464 0% 100% 3
6 ERATO YANAGISAWA ORPHAN RECEPTOR PROJECT 39191 0% 46% 6
7 STANFORD NARCOLEPSY 35382 0% 50% 5
8 DRUG DISCOVERY PRECLIN DEV 34730 0% 27% 9
9 EXPLORATORY ADV TECHNOL YANAGISAWA ORPHAN REC 32350 0% 57% 4
10 SLEEP 151A3 31846 0% 75% 3

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 REGULATORY PEPTIDES 11447 3% 1% 62
2 VITAMINS AND HORMONES 11391 1% 6% 14
3 PEPTIDES 6742 3% 1% 65
4 SLEEP 5107 2% 1% 40
5 ACTA PHYSIOLOGICA 4276 1% 2% 20
6 NEUROSCIENCE 4230 4% 0% 82
7 EUROPEAN JOURNAL OF NEUROSCIENCE 3526 2% 0% 53
8 JOURNAL OF NEUROSCIENCE 3420 4% 0% 92
9 FRONTIERS IN NEUROSCIENCE 2957 1% 1% 21
10 FRONTIERS IN BEHAVIORAL NEUROSCIENCE 2923 1% 1% 18

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 OREXIN 7193049 36% 65% 778 Search OREXIN Search OREXIN
2 HYPOCRETIN 3548480 19% 62% 404 Search HYPOCRETIN Search HYPOCRETIN
3 OREXIN A 2656286 11% 82% 228 Search OREXIN+A Search OREXIN+A
4 OREXIN RECEPTORS 992555 4% 89% 79 Search OREXIN+RECEPTORS Search OREXIN+RECEPTORS
5 SB 334867 868406 3% 93% 66 Search SB+334867 Search SB+334867
6 OREXIN 1 RECEPTOR 496860 2% 95% 37 Search OREXIN+1+RECEPTOR Search OREXIN+1+RECEPTOR
7 OREXIN RECEPTOR ANTAGONIST 428172 2% 92% 33 Search OREXIN+RECEPTOR+ANTAGONIST Search OREXIN+RECEPTOR+ANTAGONIST
8 OREXIN B 414118 1% 91% 32 Search OREXIN+B Search OREXIN+B
9 ALMOREXANT 368524 1% 96% 27 Search ALMOREXANT Search ALMOREXANT
10 OREXIN HYPOCRETIN 355694 2% 74% 34 Search OREXIN+HYPOCRETIN Search OREXIN+HYPOCRETIN

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 LI, JC , HU, Z , DE LECEA, L , (2014) THE HYPOCRETINS/OREXINS: INTEGRATORS OF MULTIPLE PHYSIOLOGICAL FUNCTIONS.BRITISH JOURNAL OF PHARMACOLOGY. VOL. 171. ISSUE 2. P. 332-350 263 88% 43
2 KUKKONEN, JP , (2013) PHYSIOLOGY OF THE OREXINERGIC/HYPOCRETINERGIC SYSTEM: A REVISIT IN 2012.AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY. VOL. 304. ISSUE 1. P. C2-C32 310 77% 41
3 GOTTER, AL , WEBBER, AL , COLEMAN, PJ , RENGER, JJ , WINROW, CJ , (2012) INTERNATIONAL UNION OF BASIC AND CLINICAL PHARMACOLOGY. LXXXVI. OREXIN RECEPTOR FUNCTION, NOMENCLATURE AND PHARMACOLOGY.PHARMACOLOGICAL REVIEWS. VOL. 64. ISSUE 3. P. 389 -420 243 83% 51
4 CHEN, QH , DE LECEA, L , HU, ZA , GAO, D , (2015) THE HYPOCRETIN/OREXIN SYSTEM: AN INCREASINGLY IMPORTANT ROLE IN NEUROPSYCHIATRY.MEDICINAL RESEARCH REVIEWS. VOL. 35. ISSUE 1. P. 152 -197 252 71% 8
5 LEONARD, CS , KUKKONEN, JP , (2014) OREXIN/HYPOCRETIN RECEPTOR SIGNALLING: A FUNCTIONAL PERSPECTIVE.BRITISH JOURNAL OF PHARMACOLOGY. VOL. 171. ISSUE 2. P. 294-313 161 86% 18
6 SAKURAI, T , (2014) THE ROLE OF OREXIN IN MOTIVATED BEHAVIOURS.NATURE REVIEWS NEUROSCIENCE. VOL. 15. ISSUE 11. P. 719 -731 125 87% 49
7 XU, TR , YANG, Y , WARD, R , GAO, LH , LIU, Y , (2013) OREXIN RECEPTORS: MULTI-FUNCTIONAL THERAPEUTIC TARGETS FOR SLEEPING DISORDERS, EATING DISORDERS, DRUG ADDICTION, CANCERS AND OTHER PHYSIOLOGICAL DISORDERS.CELLULAR SIGNALLING. VOL. 25. ISSUE 12. P. 2413-2423 155 84% 25
8 TSUJINO, N , SAKURAI, T , (2013) ROLE OF OREXIN IN MODULATING AROUSAL, FEEDING, AND MOTIVATION.FRONTIERS IN BEHAVIORAL NEUROSCIENCE. VOL. 7. ISSUE . P. - 132 85% 51
9 LOPEZ, M , TENA-SEMPERE, M , DIEGUEZ, C , (2010) CROSS-TALK BETWEEN OREXINS (HYPOCRETINS) AND THE NEUROENDOCRINE AXES (HYPOTHALAMIC-PITUITARY AXES).FRONTIERS IN NEUROENDOCRINOLOGY. VOL. 31. ISSUE 2. P. 113-127 201 70% 22
10 KHOO, SYS , BROWN, RM , (2014) OREXIN/HYPOCRETIN BASED PHARMACOTHERAPIES FOR THE TREATMENT OF ADDICTION: DORA OR SORA?.CNS DRUGS. VOL. 28. ISSUE 8. P. 713 -730 154 77% 9

Classes with closest relation at Level 1


Rank Class id link
1 5548 NARCOLEPSY//CATAPLEXY//IDIOPATHIC HYPERSOMNIA
2 13418 MELANIN CONCENTRATING HORMONE//MCH//MCH R1 ANTAGONISTS
3 27794 NPSR//NPSR1//NEUROPEPTIDE S RECEPTOR
4 33785 NEUROPEPTIDE W//GPR7//NEUROPEPTIDE B
5 18644 A2 NORADRENERGIC NEURONS//LASER CATAPULT MICRODISSECTION//GLUCOSE SENSING
6 5466 PEDUNCULOPONTINE NUCLEUS//PEDUNCULOPONTINE TEGMENTAL NUCLEUS//REM SLEEP
7 5686 SLEEP HOMEOSTASIS//K COMPLEX//SLOW WAVE ACTIVITY
8 20870 CORTICOTROPIN LIKE INTERMEDIATE LOBE PEPTIDE//5 HT1A BLOCKADE//SLEEP WAKING PHASES
9 15944 DISTAL SKIN TEMPERATURE//HEATING VENTILAT AIR CONDITIONING GAS ENGN//SKIN TEMPERATURES
10 6960 HYPOTHALAM//HYPOTHALAMUS//LEPTIN RESISTANCE

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