Class information for:
Level 1: LINOMIDE//LAQUINIMOD//TASQUINIMOD

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
26412 255 32.5 83%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
207 3       MULTIPLE SCLEROSIS//MYASTHENIA GRAVIS//MULTIPLE SCLEROSIS JOURNAL 52279
58 2             MULTIPLE SCLEROSIS//MULTIPLE SCLEROSIS JOURNAL//NEUROMYELITIS OPTICA 29459
26412 1                   LINOMIDE//LAQUINIMOD//TASQUINIMOD 255

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 LINOMIDE authKW 5940992 24% 81% 61
2 LAQUINIMOD authKW 1900100 11% 55% 29
3 TASQUINIMOD authKW 1014315 5% 71% 12
4 ROQUINIMEX authKW 997883 4% 83% 10
5 QUINOLINE 3 CARBOXAMIDE authKW 498941 2% 83% 5
6 GLOBAL INNOVAT RD address 374204 2% 63% 5
7 ABR 215050 authKW 359239 1% 100% 3
8 ABR 215062 authKW 359239 1% 100% 3
9 2 4 DISUBSTITUTED QUINAZOLINE DERIVATIVES authKW 239493 1% 100% 2
10 SPINAL CORD MOTONEURONS authKW 239493 1% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Immunology 1218 34% 0% 86
2 Pharmacology & Pharmacy 172 17% 0% 44
3 Oncology 164 15% 0% 38
4 Transplantation 132 5% 0% 13
5 Clinical Neurology 114 11% 0% 27
6 Neurosciences 106 14% 0% 36
7 Urology & Nephrology 47 5% 0% 12
8 Chemistry, Medicinal 29 4% 0% 10
9 Rheumatology 21 2% 0% 5
10 Endocrinology & Metabolism 20 5% 0% 12

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 GLOBAL INNOVAT RD 374204 2% 63% 5
2 ANALYT BIG DATA 119746 0% 100% 1
3 GENITORURINARY PROGRAM 119746 0% 100% 1
4 GRP BMD 119746 0% 100% 1
5 GRP EXPT OPHTHALMOBIOL GOBE 119746 0% 100% 1
6 IMMUNOL GRPSECT IMMUNOL 119746 0% 100% 1
7 MED CHEM PHARMACOGNESY 119746 0% 100% 1
8 RHINE MAIN NEUROSCI NETWORK RMN2 NEUROL 119746 0% 100% 1
9 TEVA INNOVAT DEV 119746 0% 100% 1
10 TEVA STAT DATA MANAGEMENT TEAM 119746 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF NEUROIMMUNOLOGY 5757 7% 0% 18
2 THERAPEUTIC ADVANCES IN NEUROLOGICAL DISORDERS 3127 1% 1% 2
3 INTERNATIONAL IMMUNOPHARMACOLOGY 2760 4% 0% 10
4 AUTOIMMUNITY 2056 2% 0% 6
5 PROSTATE 1677 3% 0% 8
6 EXPERT REVIEW OF CLINICAL PHARMACOLOGY 1284 1% 1% 2
7 EOS-RIVISTA DI IMMUNOLOGIA ED IMMUNOFARMACOLOGIA 878 1% 0% 2
8 MULTIPLE SCLEROSIS 854 1% 0% 2
9 CLINICAL IMMUNOLOGY 398 1% 0% 3
10 ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY 387 0% 0% 1

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 LINOMIDE 5940992 24% 81% 61 Search LINOMIDE Search LINOMIDE
2 LAQUINIMOD 1900100 11% 55% 29 Search LAQUINIMOD Search LAQUINIMOD
3 TASQUINIMOD 1014315 5% 71% 12 Search TASQUINIMOD Search TASQUINIMOD
4 ROQUINIMEX 997883 4% 83% 10 Search ROQUINIMEX Search ROQUINIMEX
5 QUINOLINE 3 CARBOXAMIDE 498941 2% 83% 5 Search QUINOLINE+3+CARBOXAMIDE Search QUINOLINE+3+CARBOXAMIDE
6 ABR 215050 359239 1% 100% 3 Search ABR+215050 Search ABR+215050
7 ABR 215062 359239 1% 100% 3 Search ABR+215062 Search ABR+215062
8 2 4 DISUBSTITUTED QUINAZOLINE DERIVATIVES 239493 1% 100% 2 Search 2+4+DISUBSTITUTED+QUINAZOLINE+DERIVATIVES Search 2+4+DISUBSTITUTED+QUINAZOLINE+DERIVATIVES
9 SPINAL CORD MOTONEURONS 239493 1% 100% 2 Search SPINAL+CORD+MOTONEURONS Search SPINAL+CORD+MOTONEURONS
10 1 2 DIHYDRO 4 HYDROXY 2 OXOQUINOLINE 3 CARBOXAMIDES 119746 0% 100% 1 Search 1+2+DIHYDRO+4+HYDROXY+2+OXOQUINOLINE+3+CARBOXAMIDES Search 1+2+DIHYDRO+4+HYDROXY+2+OXOQUINOLINE+3+CARBOXAMIDES

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 HAINKE, U , THOMAS, K , ZIEMSSEN, T , (2016) LAQUINIMOD IN THE TREATMENT OF RELAPSING REMITTING MULTIPLE SCLEROSIS.EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY. VOL. 12. ISSUE 6. P. 701 -709 25 83% 0
2 THONE, J , LINKER, RA , (2016) LAQUINIMOD IN THE TREATMENT OF MULTIPLE SCLEROSIS: A REVIEW OF THE DATA SO FAR.DRUG DESIGN DEVELOPMENT AND THERAPY. VOL. 10. ISSUE . P. - 23 82% 0
3 HAGGIAG, S , RUGGIERI, S , GASPERINI, C , (2013) EFFICACY AND SAFETY OF LAQUINIMOD IN MULTIPLE SCLEROSIS: CURRENT STATUS.THERAPEUTIC ADVANCES IN NEUROLOGICAL DISORDERS. VOL. 6. ISSUE 6. P. 343-352 20 91% 6
4 HEDLUND, G , LINK, H , ZHU, J , XIAO, BG , (2001) EFFECTS OF LINOMIDE ON IMMUNE CELLS AND CYTOKINES INHIBIT AUTOIMMUNE PATHOLOGIES OF THE CENTRAL AND PERIPHERAL NERVOUS SYSTEM.INTERNATIONAL IMMUNOPHARMACOLOGY. VOL. 1. ISSUE 6. P. 1123 -1130 38 64% 6
5 NOSEWORTHY, JH , WOLINSKY, JS , LUBLIN, FD , WHITAKER, JN , LINDE, A , GJORSTRUP, P , SULLIVAN, HC , (2000) LINOMIDE IN RELAPSING AND SECONDARY PROGRESSIVE MS - PART I: TRIAL DESIGN AND CLINICAL RESULTS.NEUROLOGY. VOL. 54. ISSUE 9. P. 1726-1733 26 79% 116
6 THONE, J , GOLD, R , (2013) REVIEW OF LAQUINIMOD AND ITS THERAPEUTIC POTENTIAL IN MULTIPLE SCLEROSIS.EXPERT OPINION ON PHARMACOTHERAPY. VOL. 14. ISSUE 18. P. 2545-2552 21 75% 0
7 HARTOFT-NIELSEN, ML , RASMUSSEN, AK , KAAS, A , BOCK, T , BUSCHARD, K , FELDT-RASMUSSEN, U , (2001) LINOMIDE DOES NOT PREVENT SPONTANEOUS AUTOIMMUNE THYROIDITIS IN NOD MICE.AUTOIMMUNITY. VOL. 33. ISSUE 2. P. 79 -+ 23 85% 1
8 CONSTANTINESCU, SE , CONSTANTINESCU, CS , (2016) LAQUINIMOD (ABR-215062) FOR THE TREATMENT OF RELAPSING MULTIPLE SCLEROSIS.EXPERT REVIEW OF CLINICAL PHARMACOLOGY. VOL. 9. ISSUE 1. P. 49 -57 19 63% 1
9 LEHMANN, D , KARUSSIS, DM , FLURESCO, D , MIZRACHIKOLL, R , OVADIA, H , SHEZEN, E , KALLAND, T , ABRAMSKY, O , (1997) IMMUNOMODULATION OF AUTOIMMUNITY BY LINOMIDE: INHIBITION OF ANTIGEN PRESENTATION THROUGH DOWN REGULATION OF MACROPHAGE ACTIVITY IN THE MODEL OF EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS.JOURNAL OF NEUROIMMUNOLOGY. VOL. 74. ISSUE 1-2. P. 102-110 24 86% 31
10 BOYKO, AN , GUSEV, EI , (2013) LAQUINIMOD IS AN ORAL DRUG WITH A MARKED NEUROPROTECTIVE EFFECT FOR PATHOGENETIC TREATMENT OF MULTIPLE SCLEROSIS (REVIEW).ZHURNAL NEVROLOGII I PSIKHIATRII IMENI S S KORSAKOVA. VOL. 113. ISSUE 2. P. 93 -99 16 80% 0

Classes with closest relation at Level 1


Rank Class id link
1 35824 INO 2628 CZ//EFFICIENCY OF ENTEROHEPATIC CIRCULATION//MNP001
2 22413 ALEMTUZUMAB//DACLIZUMAB//MS CLIN CENT TEXAS
3 17038 ORGAN SYNTH GRP//4 HYDROXY 2 OXO 1 2 DIHYDROQUINOLINE 3 CARBOXAMIDES//4 HYDROXY 2 OXOQUINOLINE 3 CARBOXYLIC ACIDS
4 10755 S100A9//S100A8//CALPROTECTIN
5 1131 INTERFERON BETA//MULTIPLE SCLEROSIS//GLATIRAMER ACETATE
6 20983 DEOXYSPERGUALIN//15 DEOXYSPERGUALIN//AXE IMMUNOL
7 14186 GLATIRAMER ACETATE//PROTECTIVE AUTOIMMUNITY//COPOLYMER 1
8 37653 VARITRIOL//ORGAN CHEM CPC 2//LUNG CARCINOMA A549 CELL LINE
9 28360 LOBUND//3 2 DIMETHYL 4 AMINOBIPHENYL//PROSTATE SEMINAL VESICLE CANCER
10 22994 DIMETHYL FUMARATE//FUMARIC ACID ESTERS//MONOMETHYL FUMARATE

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