Class information for:
Level 1: CONGENITAL ADRENAL HYPERPLASIA//21 HYDROXYLASE DEFICIENCY//CYP21A2

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
2552 2210 29.6 69%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
284 3       POLYCYSTIC OVARY SYNDROME//ENDOCRINOLOGY & METABOLISM//CORTISOL 42633
909 2             CONGENITAL ADRENAL HYPERPLASIA//21 HYDROXYLASE DEFICIENCY//ENDOCRINE RESEARCH 11246
2552 1                   CONGENITAL ADRENAL HYPERPLASIA//21 HYDROXYLASE DEFICIENCY//CYP21A2 2210

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CONGENITAL ADRENAL HYPERPLASIA authKW 4194865 23% 59% 514
2 21 HYDROXYLASE DEFICIENCY authKW 2436919 10% 84% 210
3 CYP21A2 authKW 650682 3% 77% 61
4 11 BETA HYDROXYLASE DEFICIENCY authKW 388546 1% 94% 30
5 21 HYDROXYLASE authKW 381223 2% 56% 49
6 CAH authKW 370173 2% 62% 43
7 17 HYDROXYPROGESTERONE authKW 369812 2% 51% 52
8 CYP21 authKW 288686 1% 65% 32
9 CYP21A2 GENE authKW 276302 1% 100% 20
10 STEROID 21 HYDROXYLASE authKW 215681 1% 71% 22

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Endocrinology & Metabolism 37180 50% 0% 1099
2 Pediatrics 5269 17% 0% 386
3 Medical Laboratory Technology 1992 5% 0% 115
4 Genetics & Heredity 1081 10% 0% 231
5 Obstetrics & Gynecology 1009 7% 0% 159
6 Medicine, General & Internal 311 7% 0% 158
7 Reproductive Biology 275 3% 0% 56
8 Medicine, Research & Experimental 84 4% 0% 78
9 Andrology 57 0% 0% 8
10 Biochemistry & Molecular Biology 24 8% 0% 176

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ADRENAL STEROID DISORDERS PROGRAM 117015 1% 71% 12
2 PAEDIAT ENDOCRINOL 833 55260 0% 100% 4
3 PEDIAT ENDOCRINOL 54184 6% 3% 130
4 YUAN SHAN 48642 0% 39% 9
5 DISCIPLINA ENDOCRINOL HORMONIOS GENET MOL 41445 0% 100% 3
6 ENDOCRINOL INFANTILE 41445 0% 100% 3
7 ENDOCRINOL MOL MALAD RA 33149 0% 40% 6
8 ADRENAL STEROID DISORDERS 28776 0% 42% 5
9 ADRENAL STEROID DISORDER PROGRAM 27630 0% 100% 2
10 ENDOCRINOL DIABETOL METAB PEDIAT 27630 0% 100% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 37270 11% 1% 253
2 HORMONE RESEARCH 32092 4% 3% 90
3 JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM 23477 4% 2% 78
4 CLINICAL ENDOCRINOLOGY 14189 4% 1% 88
5 HORMONE RESEARCH IN PAEDIATRICS 12170 1% 3% 27
6 JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION 6393 2% 1% 48
7 EUROPEAN JOURNAL OF ENDOCRINOLOGY 5583 2% 1% 46
8 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 4557 2% 1% 55
9 ENDOCRINE RESEARCH 4027 1% 1% 20
10 STEROIDS 3209 1% 1% 32

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 CONGENITAL ADRENAL HYPERPLASIA 4194865 23% 59% 514 Search CONGENITAL+ADRENAL+HYPERPLASIA Search CONGENITAL+ADRENAL+HYPERPLASIA
2 21 HYDROXYLASE DEFICIENCY 2436919 10% 84% 210 Search 21+HYDROXYLASE+DEFICIENCY Search 21+HYDROXYLASE+DEFICIENCY
3 CYP21A2 650682 3% 77% 61 Search CYP21A2 Search CYP21A2
4 11 BETA HYDROXYLASE DEFICIENCY 388546 1% 94% 30 Search 11+BETA+HYDROXYLASE+DEFICIENCY Search 11+BETA+HYDROXYLASE+DEFICIENCY
5 21 HYDROXYLASE 381223 2% 56% 49 Search 21+HYDROXYLASE Search 21+HYDROXYLASE
6 CAH 370173 2% 62% 43 Search CAH Search CAH
7 17 HYDROXYPROGESTERONE 369812 2% 51% 52 Search 17+HYDROXYPROGESTERONE Search 17+HYDROXYPROGESTERONE
8 CYP21 288686 1% 65% 32 Search CYP21 Search CYP21
9 CYP21A2 GENE 276302 1% 100% 20 Search CYP21A2+GENE Search CYP21A2+GENE
10 STEROID 21 HYDROXYLASE 215681 1% 71% 22 Search STEROID+21+HYDROXYLASE Search STEROID+21+HYDROXYLASE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 WHITE, PC , SPEISER, PW , (2000) CONGENITAL ADRENAL HYPERPLASIA DUE TO 21-HYDROXYLASE DEFICIENCY.ENDOCRINE REVIEWS. VOL. 21. ISSUE 3. P. 245 -291 288 61% 607
2 SPEISER, PW , AZZIZ, R , BASKIN, LS , GHIZZONI, L , HENSLE, TW , MERKE, DP , MEYER-BAHLBURG, HFL , MILLER, WL , MONTORI, VM , OBERFIELD, SE , ET AL (2010) CONGENITAL ADRENAL HYPERPLASIA DUE TO STEROID 21-HYDROXYLASE DEFICIENCY: AN ENDOCRINE SOCIETY CLINICAL PRACTICE GUIDELINE.JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. VOL. 95. ISSUE 9. P. 4133 -4160 165 70% 271
3 FALHAMMAR, H , NORDENSTROM, A , (2015) NONCLASSIC CONGENITAL ADRENAL HYPERPLASIA DUE TO 21-HYDROXYLASE DEFICIENCY: CLINICAL PRESENTATION, DIAGNOSIS, TREATMENT, AND OUTCOME.ENDOCRINE. VOL. 50. ISSUE 1. P. 32 -50 143 82% 2
4 THOREN, M , FALHAMMAR, H , (2012) CLINICAL OUTCOMES IN THE MANAGEMENT OF CONGENITAL ADRENAL HYPERPLASIA.ENDOCRINE. VOL. 41. ISSUE 3. P. 355 -373 119 80% 14
5 RIEPE, FG , SIPPELL, WG , (2007) RECENT ADVANCES IN DIAGNOSIS, TREATMENT, AND OUTCOME OF CONGENITAL ADRENAL HYPERPLASIA DUE TO 21-HYDROXYLASE DEFICIENCY.REVIEWS IN ENDOCRINE & METABOLIC DISORDERS. VOL. 8. ISSUE 4. P. 349 -363 102 83% 36
6 TURCU, AF , AUCHUS, RJ , (2015) ADRENAL STEROIDOGENESIS AND CONGENITAL ADRENAL HYPERPLASIA.ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA. VOL. 44. ISSUE 2. P. 275 -+ 87 73% 6
7 REISCH, N , ARLT, W , KRONE, N , (2011) HEALTH PROBLEMS IN CONGENITAL ADRENAL HYPERPLASIA DUE TO 21-HYDROXYLASE DEFICIENCY.HORMONE RESEARCH IN PAEDIATRICS. VOL. 76. ISSUE 2. P. 73 -85 77 88% 32
8 PARSA, AA , NEW, MI , (2017) STEROID 21-HYDROXYLASE DEFICIENCY IN CONGENITAL ADRENAL HYPERPLASIA.JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. VOL. 165. ISSUE . P. 2 -11 60 67% 1
9 MERKE, DP , BORNSTEIN, SR , (2005) CONGENITAL ADRENAL HYPERPLASIA.LANCET. VOL. 365. ISSUE 9477. P. 2125-2136 88 71% 272
10 FALHAMMAR, H , WEDELL, A , NORDENSTROM, A , (2015) BIOCHEMICAL AND GENETIC DIAGNOSIS OF 21-HYDROXYLASE DEFICIENCY.ENDOCRINE. VOL. 50. ISSUE 2. P. 306 -314 69 88% 2

Classes with closest relation at Level 1


Rank Class id link
1 24408 3 BETA HYDROXYSTEROID DEHYDROGENASE//HSD3B2 GENE//SHORT CHAIN OXIDOREDUCTASE
2 10101 ANTLEY BIXLER SYNDROME//ADRENARCHE//17 ALPHA HYDROXYLASE DEFICIENCY
3 8842 DISORDERS OF SEX DEVELOPMENT//INTERSEX//AMBIGUOUS GENITALIA
4 33105 ECTOPIC ADRENAL//ECTOPIC ADRENAL TISSUE//ADRENOHEPATIC FUSION
5 31199 HLTH SCI SW MED BIOCHEM//HLTH SCI SW MED OBSTET GYNECOL//20A DIHYDROPROGESTERONE
6 13350 HIRSUTISM//IDIOPATHIC HIRSUTISM//ANDROSTANEDIOL GLUCURONIDE
7 11660 ADRENAL INSUFFICIENCY//ADDISONS DISEASE//ADRENAL CRISIS
8 14044 19 NORDEOXYCORTICOSTERONE//ALDOSTERONE BIOSYNTHESIS//ALDOSTERONE SYNTHASE DEFICIENCY
9 17026 FD LC MS MS METHOD//FLUOROGENIC DERIVATIZATION//DAABD CL
10 16461 CHRONIC LUNG DISEASE//BRONCHOPULMONARY DYSPLASIA//POSTNATAL STEROIDS

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