Class information for:
Level 1: AMBROXOL//BROMHEXINE//AMBROXOL HYDROCHLORIDE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
24616 306 24.7 53%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
285 3       ERDOSTEINE//PEROXIREDOXIN//GLUTATHIONE 42405
3501 2             AMBROXOL//ERDOSTEINE//N ACETYLCYSTEINE 1436
24616 1                   AMBROXOL//BROMHEXINE//AMBROXOL HYDROCHLORIDE 306

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 AMBROXOL authKW 5395937 32% 56% 97
2 BROMHEXINE authKW 800502 6% 42% 19
3 AMBROXOL HYDROCHLORIDE authKW 748397 5% 50% 15
4 BROMHEXINE HYDROCHLORIDE authKW 271637 2% 39% 7
5 PECTIN GELS authKW 256592 2% 43% 6
6 MUCOKINETIC ACTIVITY authKW 199577 1% 100% 2
7 IN SITU GELATION authKW 132490 3% 15% 9
8 2 WAY CROSSOVER DESIGN authKW 99788 0% 100% 1
9 44 DIMETHYLAMINO BENZYLIDENE AMINO BENZENE SULPHONAMIDE authKW 99788 0% 100% 1
10 96 WELL FORMAT LLE authKW 99788 0% 100% 1

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Pharmacology & Pharmacy 1312 39% 0% 119
2 Chemistry, Analytical 913 24% 0% 74
3 Respiratory System 450 10% 0% 32
4 Chemistry, Medicinal 147 7% 0% 22
5 Biochemical Research Methods 88 7% 0% 20
6 Obstetrics & Gynecology 20 3% 0% 10
7 Chemistry, Multidisciplinary 16 8% 0% 24
8 Immunology 14 5% 0% 16
9 Medicine, Research & Experimental 12 4% 0% 11
10 CYTOLOGY & HISTOLOGY 11 0% 0% 1

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CHINA FOOD DRUG ADM 99788 0% 100% 1
2 CLIN PHARMACOL INTERNAL DIS PROPEDEUT 99788 0% 100% 1
3 FAOYUM BRANCH 99788 0% 100% 1
4 QUAL CONTROL NUCL 99788 0% 100% 1
5 YB CHAYAN PHARM 99788 0% 100% 1
6 A BOADILLA MONTE CC EXPT TECN 49893 0% 50% 1
7 SPETTROSCOPIA RAMAN 33261 0% 33% 1
8 NEONATOL CHARITE 24946 0% 25% 1
9 BIOL FOR 19956 0% 20% 1
10 MODERN MED 17956 1% 6% 3

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 INVESTIGACION MEDICA INTERNACIONAL 10085 1% 3% 3
2 REVIEWS IN PERINATAL MEDICINE 9070 0% 9% 1
3 JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS 3633 7% 0% 20
4 RESPIRATION 3368 4% 0% 11
5 BOLLETTINO DELL ISTITUTO SIEROTERAPICO MILANESE 2402 1% 1% 3
6 INFLAMMATION RESEARCH 2273 3% 0% 8
7 ARZNEIMITTEL-FORSCHUNG/DRUG RESEARCH 1442 3% 0% 8
8 ZENTRALBLATT FUR GYNAKOLOGIE 1391 1% 0% 4
9 LUNG 1281 2% 0% 5
10 BRAZILIAN JOURNAL OF PHARMACEUTICAL SCIENCES 1273 1% 0% 3

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 AMBROXOL 5395937 32% 56% 97 Search AMBROXOL Search AMBROXOL
2 BROMHEXINE 800502 6% 42% 19 Search BROMHEXINE Search BROMHEXINE
3 AMBROXOL HYDROCHLORIDE 748397 5% 50% 15 Search AMBROXOL+HYDROCHLORIDE Search AMBROXOL+HYDROCHLORIDE
4 BROMHEXINE HYDROCHLORIDE 271637 2% 39% 7 Search BROMHEXINE+HYDROCHLORIDE Search BROMHEXINE+HYDROCHLORIDE
5 PECTIN GELS 256592 2% 43% 6 Search PECTIN+GELS Search PECTIN+GELS
6 MUCOKINETIC ACTIVITY 199577 1% 100% 2 Search MUCOKINETIC+ACTIVITY Search MUCOKINETIC+ACTIVITY
7 IN SITU GELATION 132490 3% 15% 9 Search IN+SITU+GELATION Search IN+SITU+GELATION
8 2 WAY CROSSOVER DESIGN 99788 0% 100% 1 Search 2+WAY+CROSSOVER+DESIGN Search 2+WAY+CROSSOVER+DESIGN
9 44 DIMETHYLAMINO BENZYLIDENE AMINO BENZENE SULPHONAMIDE 99788 0% 100% 1 Search 44+DIMETHYLAMINO+BENZYLIDENE+AMINO+BENZENE+SULPHONAMIDE Search 44+DIMETHYLAMINO+BENZYLIDENE+AMINO+BENZENE+SULPHONAMIDE
10 96 WELL FORMAT LLE 99788 0% 100% 1 Search 96+WELL+FORMAT+LLE Search 96+WELL+FORMAT+LLE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 VUJOVIC, MM , JOKANOVIC, M , NIKOLIC, GM , (2016) DEVELOPMENT OF A NEW ULTRA-HIGH PERFORMANCE LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY METHOD FOR DETERMINATION OF AMBROXOL HYDROCHLORIDE IN SERUM WITH PHARMACOKINETIC APPLICATION.HEMIJSKA INDUSTRIJA. VOL. 70. ISSUE 4. P. 409 -418 23 72% 0
2 MALERBA, M , RAGNOLI, B , (2008) AMBROXOL IN THE 21ST CENTURY: PHARMACOLOGICAL AND CLINICAL UPDATE.EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY. VOL. 4. ISSUE 8. P. 1119-1129 30 49% 44
3 LI, J , BI, YW , WANG, L , SUN, FL , CHEN, Z , XU, GL , FAN, GR , (2012) BETA-CYCLODEXTRIN ENHANCED ON-LINE ORGANIC SOLVENT FIELD-AMPLIFIED SAMPLE STACKING IN CAPILLARY ZONE ELECTROPHORESIS FOR ANALYSIS OF AMBROXOL IN HUMAN PLASMA, FOLLOWING LIQUID-LIQUID EXTRACTION IN THE 96-WELL FORMAT.JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS. VOL. 66. ISSUE . P. 218 -224 18 67% 7
4 PALEARI, D , ROSSI, GA , NICOLINI, G , OLIVIERI, D , (2011) AMBROXOL: A MULTIFACETED MOLECULE WITH ADDITIONAL THERAPEUTIC POTENTIALS IN RESPIRATORY DISORDERS OF CHILDHOOD.EXPERT OPINION ON DRUG DISCOVERY. VOL. 6. ISSUE 11. P. 1203 -1214 29 43% 6
5 FELIX, FS , BRETT, CMA , ANGNES, L , (2008) FLOW INJECTION ANALYSIS USING CARBON FILM RESISTOR ELECTRODES FOR AMPEROMETRIC DETERMINATION OF AMBROXOL.TALANTA. VOL. 76. ISSUE 1. P. 128-133 23 58% 9
6 PRABU, SL , SHIRWAIKAR, AA , SHIRWAIKAR, A , KUMAR, CD , KUMAR, GA , (2008) SIMULTANEOUS UV SPECTROPHOTOMETRIC ESTIMATION OF AMBROXOL HYDROCHLORIDE AND LEVOCETIRIZINE DIHYDROCHLORIDE.INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES. VOL. 70. ISSUE 2. P. 236-U4 12 100% 8
7 SU, FL , WANG, F , GAO, W , LI, HD , (2007) DETERMINATION OF AMBROXOL IN HUMAN PLASMA BY HIGH PERFORMANCE LIQUID CHROMATOGRAPHY-ELECTROSPRAY IONIZATION MASS SPECTROMETRY (HPLC-MS/ESI).JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES. VOL. 853. ISSUE 1-2. P. 364-368 12 100% 14
8 EMARA, S , KAMAL, M , KAWI, MA , (2012) ON-LINE SAMPLE CLEANUP AND ENRICHMENT CHROMATOGRAPHIC TECHNIQUE FOR THE DETERMINATION OF AMBROXOL IN HUMAN SERUM.JOURNAL OF CHROMATOGRAPHIC SCIENCE. VOL. 50. ISSUE 2. P. 91 -96 13 81% 3
9 DEMIRCIGIL, BT , USLU, B , OZKAN, Y , OZKAN, SA , SENTURK, Z , (2003) VOLTAMMETRIC OXIDATION OF AMBROXOL AND APPLICATION TO ITS DETERMINATION IN PHARMACEUTICALS AND IN DRUG DISSOLUTION STUDIES.ELECTROANALYSIS. VOL. 15. ISSUE 3. P. 230 -234 15 83% 14
10 POSPISILOVA, M , POLASEK, M , JOKL, V , (2001) DETERMINATION OF AMBROXOL OF BROMHEXINE IN PHARMACEUTICALS BY CAPILLARY ISOTACHOPHORESIS.JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS. VOL. 24. ISSUE 3. P. 421-428 16 80% 28

Classes with closest relation at Level 1


Rank Class id link
1 30259 AMYLOCAINE//BARIUM LEAD SULFATE CO PRECIPITATE//CONTINUOUS ION PAIR EXTRACTION
2 23400 LORATADINE//CETIRIZINE DIHYDROCHLORIDE//FEXOFENADINE
3 24645 ERDOSTEINE//S CARBOXYMETHYL L CYSTEINE//FUDOSTEINE
4 18537 N ACETYLCYSTEINE//CARDIOVASC SURG CIRCULAT PHYSIOPATHOL//CYTIOLONE
5 35548 ANALPHYLACTIC SHOCK//DEXTRAN IMMUNOCONJUGATE//MASTER CELL
6 11040 ANTENATAL CORTICOSTEROIDS//BETAMETHASONE//ANTENATAL GLUCOCORTICOIDS
7 7455 PARACETAMOL//METHOCARBAMOL//ACETAMINOPHEN
8 30067 ZALTOPROFEN//CAS 18683 91 5//CHILLS DRUG THERAPY
9 37077 INJECTION SOLVENT//ALVEOLAR MACROPHAGE GUINEA PIG//ANALYTE SOLVENT
10 29282 DROTAVERINE HYDROCHLORIDE//DROTAVERINE//NIFUROXAZIDE

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