Class information for:
Level 1: PANITUMUMAB//CETUXIMAB//KRAS

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
2234 2314 41.7 87%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
6 4 GASTROENTEROLOGY & HEPATOLOGY//ONCOLOGY//SURGERY 1371034
109 3       RECTAL CANCER//COLORECTAL CANCER//COLONOSCOPY 71522
1071 2             LYNCH SYNDROME//MICROSATELLITE INSTABILITY//HNPCC 9941
2234 1                   PANITUMUMAB//CETUXIMAB//KRAS 2314

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PANITUMUMAB authKW 2026444 10% 64% 240
2 CETUXIMAB authKW 1602379 19% 27% 442
3 KRAS authKW 1341608 16% 27% 381
4 METASTATIC COLORECTAL CANCER authKW 510814 7% 23% 167
5 KRAS MUTATION authKW 445694 5% 27% 124
6 COLORECTAL CANCER authKW 367712 33% 4% 759
7 BRAF authKW 305888 8% 13% 183
8 ANTI EGFR THERAPY authKW 155735 1% 54% 22
9 DIGEST ONCOL UNIT address 152687 2% 24% 48
10 ANTI EGFR MONOCLONAL ANTIBODIES authKW 141213 1% 63% 17

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Oncology 38383 66% 0% 1521
2 Pathology 2318 10% 0% 220
3 Medical Laboratory Technology 779 3% 0% 76
4 Gastroenterology & Hepatology 617 6% 0% 132
5 Medicine, Research & Experimental 233 5% 0% 114
6 Pharmacology & Pharmacy 192 8% 0% 185
7 Surgery 43 5% 0% 110
8 Genetics & Heredity 35 3% 0% 73
9 Biotechnology & Applied Microbiology 31 3% 0% 73
10 Cell Biology 30 4% 0% 95

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 DIGEST ONCOL UNIT 152687 2% 24% 48
2 FALCK MED ONCOL 112478 1% 47% 18
3 NIGUARDA CANC 90968 1% 34% 20
4 CELL BIOL BIOTHER Y UNIT 88132 1% 32% 21
5 MOL DIGEST ONCOL 76331 0% 64% 9
6 UNIT MED ONCOL 1 60309 0% 57% 8
7 UK NEQAS MOL GENET 58769 0% 64% 7
8 MED ONCOL 52885 19% 1% 432
9 RADIAT ONCOL MED PHYS BIOPHYS 52776 0% 100% 4
10 DNA REPAIR GENOME STABIL RADIAT ONCOL 47119 0% 71% 5

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CLINICAL COLORECTAL CANCER 129416 3% 14% 68
2 TARGETED ONCOLOGY 15421 1% 5% 22
3 ANNALS OF ONCOLOGY 8223 3% 1% 72
4 JOURNAL OF MOLECULAR DIAGNOSTICS 7191 1% 2% 25
5 CLINICAL CANCER RESEARCH 5442 3% 1% 79
6 BRITISH JOURNAL OF CANCER 5087 4% 0% 84
7 BMC CANCER 4850 2% 1% 52
8 JOURNAL OF CLINICAL ONCOLOGY 3890 3% 0% 70
9 MOLECULAR DIAGNOSIS & THERAPY 3495 0% 2% 11
10 ONCOLOGIST 3396 1% 1% 24

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 PANITUMUMAB 2026444 10% 64% 240 Search PANITUMUMAB Search PANITUMUMAB
2 CETUXIMAB 1602379 19% 27% 442 Search CETUXIMAB Search CETUXIMAB
3 KRAS 1341608 16% 27% 381 Search KRAS Search KRAS
4 METASTATIC COLORECTAL CANCER 510814 7% 23% 167 Search METASTATIC+COLORECTAL+CANCER Search METASTATIC+COLORECTAL+CANCER
5 KRAS MUTATION 445694 5% 27% 124 Search KRAS+MUTATION Search KRAS+MUTATION
6 COLORECTAL CANCER 367712 33% 4% 759 Search COLORECTAL+CANCER Search COLORECTAL+CANCER
7 BRAF 305888 8% 13% 183 Search BRAF Search BRAF
8 ANTI EGFR THERAPY 155735 1% 54% 22 Search ANTI+EGFR+THERAPY Search ANTI+EGFR+THERAPY
9 ANTI EGFR MONOCLONAL ANTIBODIES 141213 1% 63% 17 Search ANTI+EGFR+MONOCLONAL+ANTIBODIES Search ANTI+EGFR+MONOCLONAL+ANTIBODIES
10 MCRC 128713 1% 51% 19 Search MCRC Search MCRC

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 MALAPELLE, U , CARLOMAGNO, C , DE LUCA, C , BELLEVICINE, C , TRONCONE, G , (2014) KRAS TESTING IN METASTATIC COLORECTAL CARCINOMA: CHALLENGES, CONTROVERSIES, BREAKTHROUGHS AND BEYOND.JOURNAL OF CLINICAL PATHOLOGY. VOL. 67. ISSUE 1. P. 1 -9 108 86% 11
2 CUSTODIO, A , FELIU, J , (2013) PROGNOSTIC AND PREDICTIVE BIOMARKERS FOR EPIDERMAL GROWTH FACTOR RECEPTOR-TARGETED THERAPY IN COLORECTAL CANCER: BEYOND KRAS MUTATIONS.CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY. VOL. 85. ISSUE 1. P. 45 -81 108 57% 45
3 YANG, M , LIU, BR , LIU, J , HU, J , CHENG, L , REN, W , XIE, L , QIAN, XP , (2016) BIOMARKERS PREDICTING RESISTANCE TO EPIDERMAL GROWTH FACTOR RECEPTOR-TARGETED THERAPY IN METASTATIC COLORECTAL CANCER WITH WILD-TYPE KRAS.ONCOTARGETS AND THERAPY. VOL. 9. ISSUE . P. 557 -565 73 76% 4
4 MISALE, S , DI NICOLANTONIO, F , SARTORE-BIANCHI, A , SIENA, S , BARDELLI, A , (2014) RESISTANCE TO ANTI-EGFR THERAPY IN COLORECTAL CANCER: FROM HETEROGENEITY TO CONVERGENT EVOLUTION.CANCER DISCOVERY. VOL. 4. ISSUE 11. P. 1269 -1280 66 80% 46
5 LUO, HY , XU, RH , (2014) PREDICTIVE AND PROGNOSTIC BIOMARKERS WITH THERAPEUTIC TARGETS IN ADVANCED COLORECTAL CANCER.WORLD JOURNAL OF GASTROENTEROLOGY. VOL. 20. ISSUE 14. P. 3858-3874 86 69% 9
6 BRONTE, G , SILVESTRIS, N , CASTIGLIA, M , GALVANO, A , PASSIGLIA, F , SORTINO, G , CICERO, G , ROLFO, C , PEETERS, M , BAZAN, V , ET AL (2015) NEW FINDINGS ON PRIMARY AND ACQUIRED RESISTANCE TO ANTI-EGFR THERAPY IN METASTATIC COLORECTAL CANCER: DO ALL ROADS LEAD TO RAS?.ONCOTARGET. VOL. 6. ISSUE 28. P. 24780 -24796 71 71% 14
7 HERREROS-VILLANUEVA, M , CHEN, CC , YUAN, SSF , LIU, TC , ER, TK , (2014) KRAS MUTATIONS: ANALYTICAL CONSIDERATIONS.CLINICA CHIMICA ACTA. VOL. 431. ISSUE . P. 211-220 81 71% 10
8 SIENA, S , SARTORE-BIANCHI, A , DI NICOLANTONIO, F , BALFOUR, J , BARDELLI, A , (2009) BIOMARKERS PREDICTING CLINICAL OUTCOME OF EPIDERMAL GROWTH FACTOR RECEPTOR-TARGETED THERAPY IN METASTATIC COLORECTAL CANCER.JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE. VOL. 101. ISSUE 19. P. 1308 -1324 66 64% 309
9 WARING, P , TIE, J , MARU, D , KARAPETIS, CS , (2016) RAS MUTATIONS AS PREDICTIVE BIOMARKERS IN CLINICAL MANAGEMENT OF METASTATIC COLORECTAL CANCER.CLINICAL COLORECTAL CANCER. VOL. 15. ISSUE 2. P. 95 -103 60 86% 2
10 TAN, C , DU, X , (2012) KRAS MUTATION TESTING IN METASTATIC COLORECTAL CANCER.WORLD JOURNAL OF GASTROENTEROLOGY. VOL. 18. ISSUE 37. P. 5171 -5180 66 85% 30

Classes with closest relation at Level 1


Rank Class id link
1 747 METASTATIC COLORECTAL CANCER//OXALIPLATIN//ADVANCED COLORECTAL CANCER
2 24187 RHGP//WHOLE GENOMIC OLIGONUCLEOTIDE MICROARRAY//12 GENE COLON CANCER ASSAY
3 4440 NIMOTUZUMAB//CETUXIMAB//EGFR
4 16698 TRICHOMEGALY//EPIDERMAL GROWTH FACTOR RECEPTOR INHIBITORS//SKIN TOXICITY
5 9828 SERRATED ADENOMA//SESSILE SERRATED ADENOMA//HYPERPLASTIC POLYP
6 15816 DCC GENE//BIOPHYS CYTOMETRY//DCC
7 21195 STOOL DNA//FECAL RNA//STOOL DNA TESTING
8 13462 HER2//GASTRIC CANCER//HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR 2
9 147 GEFITINIB//EGFR MUTATION//ERLOTINIB
10 27700 JOINT SERV BIOMARKER EVALUAT ONCOL//KI67 SCORE//LOCDIR

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