Class information for:
Level 1: FLAGELLIN//TLR5//TOLL LIKE RECEPTOR 5

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
21562 414 42.0 92%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
449 3       FAMILIAL MEDITERRANEAN FEVER//TOLL LIKE RECEPTORS//INFLAMMASOME 25887
543 2             TOLL LIKE RECEPTORS//INNATE IMMUNITY//CPG ODN 14712
21562 1                   FLAGELLIN//TLR5//TOLL LIKE RECEPTOR 5 414

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 FLAGELLIN authKW 1839259 27% 22% 113
2 TLR5 authKW 1364450 9% 50% 37
3 TOLL LIKE RECEPTOR 5 authKW 508636 5% 34% 20
4 EPITHELIAL PATHOBIOL address 301165 2% 58% 7
5 SALMONELLA FLAGELLIN authKW 236018 1% 80% 4
6 E COLI FLAGELLIN authKW 147512 0% 100% 2
7 SECT RECOMBINANT ALLERGEN THER EUT address 147512 0% 100% 2
8 HA GLOBULAR HEAD authKW 98340 0% 67% 2
9 TRUNCATED FORMS authKW 98340 0% 67% 2
10 ADJUVANT CANDIDATE authKW 73756 0% 100% 1

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Immunology 5701 56% 0% 231
2 Infectious Diseases 563 12% 0% 48
3 Microbiology 424 14% 0% 60
4 Medicine, Research & Experimental 235 10% 0% 41
5 Cell Biology 66 8% 0% 35
6 Gastroenterology & Hepatology 65 5% 0% 19
7 Physiology 51 5% 0% 20
8 Biochemistry & Molecular Biology 51 14% 0% 57
9 Respiratory System 39 3% 0% 13
10 Biotechnology & Applied Microbiology 29 5% 0% 21

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 EPITHELIAL PATHOBIOL 301165 2% 58% 7
2 SECT RECOMBINANT ALLERGEN THER EUT 147512 0% 100% 2
3 AKIRA INATE IMMUN PROJECT 73756 0% 100% 1
4 BACTERIOL VIROL HIGIENE 73756 0% 100% 1
5 BIODEF EMERGING INFECT DISSEALY VACCINE CT 73756 0% 100% 1
6 BIOINFORMAT DRUG DESIGN UNIT 73756 0% 100% 1
7 BIOL ARGENTINO BIOL 73756 0% 100% 1
8 BIOL LILLECNRS UMR 8161 73756 0% 100% 1
9 BIOMED SCI MICROBIOL GRP 73756 0% 100% 1
10 CNRS MOL IMMUNOL EMBRYOL 73756 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 INFECTION AND IMMUNITY 2996 8% 0% 33
2 VACCINE 2950 7% 0% 27
3 MUCOSAL IMMUNOLOGY 2315 1% 1% 5
4 CELLULAR & MOLECULAR IMMUNOLOGY 2241 1% 1% 5
5 JOURNAL OF IMMUNOLOGY 1853 9% 0% 37
6 AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY 1167 2% 0% 10
7 JOURNAL OF INNATE IMMUNITY 625 0% 0% 2
8 SEMINARS IN IMMUNOPATHOLOGY 602 0% 0% 2
9 MSPHERE 503 0% 1% 1
10 EXERCISE IMMUNOLOGY REVIEW 493 0% 1% 1

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 FLAGELLIN 1839259 27% 22% 113 Search FLAGELLIN Search FLAGELLIN
2 TLR5 1364450 9% 50% 37 Search TLR5 Search TLR5
3 TOLL LIKE RECEPTOR 5 508636 5% 34% 20 Search TOLL+LIKE+RECEPTOR+5 Search TOLL+LIKE+RECEPTOR+5
4 SALMONELLA FLAGELLIN 236018 1% 80% 4 Search SALMONELLA+FLAGELLIN Search SALMONELLA+FLAGELLIN
5 E COLI FLAGELLIN 147512 0% 100% 2 Search E+COLI+FLAGELLIN Search E+COLI+FLAGELLIN
6 HA GLOBULAR HEAD 98340 0% 67% 2 Search HA+GLOBULAR+HEAD Search HA+GLOBULAR+HEAD
7 TRUNCATED FORMS 98340 0% 67% 2 Search TRUNCATED+FORMS Search TRUNCATED+FORMS
8 ADJUVANT CANDIDATE 73756 0% 100% 1 Search ADJUVANT+CANDIDATE Search ADJUVANT+CANDIDATE
9 AMINO ACIDS 89 96 73756 0% 100% 1 Search AMINO+ACIDS+89+96 Search AMINO+ACIDS+89+96
10 ANTI FLAGELLIN SERUM 73756 0% 100% 1 Search ANTI+FLAGELLIN+SERUM Search ANTI+FLAGELLIN+SERUM

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 MIZEL, SB , BATES, JT , (2010) FLAGELLIN AS AN ADJUVANT: CELLULAR MECHANISMS AND POTENTIAL.JOURNAL OF IMMUNOLOGY. VOL. 185. ISSUE 10. P. 5677-5682 47 64% 122
2 ZGAIR, AK , (2012) ESCHERICHIA COLI FLAGELLIN STIMULATES PRO-INFLAMMATORY IMMUNE RESPONSE.WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY. VOL. 28. ISSUE 5. P. 2139-2146 29 69% 1
3 LOPEZ-YGLESIAS, AH , ZHAO, X , QUARLES, EK , LAI, MA , VANDENBOS, T , STRONG, RK , SMITH, KD , (2014) FLAGELLIN INDUCES ANTIBODY RESPONSES THROUGH A TLR5-AND INFLAMMASOME-INDEPENDENT PATHWAY.JOURNAL OF IMMUNOLOGY. VOL. 192. ISSUE 4. P. 1587-1596 38 43% 18
4 BATES, JT , GRAFF, AH , PHIPPS, JP , GRAYSON, JM , MIZEL, SB , (2011) ENHANCED ANTIGEN PROCESSING OF FLAGELLIN FUSION PROTEINS PROMOTES THE ANTIGEN-SPECIFIC CD8(+) T CELL RESPONSE INDEPENDENTLY OF TLR5 AND MYD88.JOURNAL OF IMMUNOLOGY. VOL. 186. ISSUE 11. P. 6255-6262 32 54% 16
5 ZHANG, L , PAN, ZM , KANG, XL , YANG, Y , KANG, H , ZHANG, N , ROSATI, JM , JIAO, XA , (2015) AMINO ACIDS 89-96 OF SALMONELLA TYPHIMURIUM FLAGELLIN REPRESENT THE MAJOR DOMAIN RESPONSIBLE FOR TLR5-INDEPENDENT ADJUVANTICITY IN THE HUMORAL IMMUNE RESPONSE.CELLULAR & MOLECULAR IMMUNOLOGY. VOL. 12. ISSUE 5. P. 625 -632 22 73% 2
6 SANDERS, CJ , MOORE, DA , WILLIAMS, IR , GEWIRTZ, AT , (2008) BOTH RADIORESISTANT AND HEMOPOIETIC CELLS PROMOTE INNATE AND ADAPTIVE IMMUNE RESPONSES TO FLAGELLIN.JOURNAL OF IMMUNOLOGY. VOL. 180. ISSUE 11. P. 7184-7192 27 63% 25
7 TERRON-EXPOSITO, R , DUDOGNON, B , GALINDO, I , QUETGLAS, JI , COLL, JM , ESCRIBANO, JM , GOMEZ-CASADO, E , (2012) ANTIBODIES AGAINST MARINOBACTER ALGICOLA AND SALMONELLA TYPHIMURIUM FLAGELLINS DO NOT CROSS-NEUTRALIZE TLR5 ACTIVATION.PLOS ONE. VOL. 7. ISSUE 11. P. - 29 53% 3
8 HONKO, AN , MIZEL, SB , (2004) MUCOSAL ADMINISTRATION OF FLAGELLIN INDUCES INNATE IMMUNITY IN THE MOUSE LUNG.INFECTION AND IMMUNITY. VOL. 72. ISSUE 11. P. 6676-6679 22 79% 67
9 MIZEL, SB , GRAFF, AH , SRIRANGANATHAN, N , ERVIN, S , LEES, CJ , LIVELY, MO , HANTGAN, RR , THOMAS, MJ , WOOD, J , BELL, B , (2009) FLAGELLIN-F1-V FUSION PROTEIN IS AN EFFECTIVE PLAGUE VACCINE IN MICE AND TWO SPECIES OF NONHUMAN PRIMATES.CLINICAL AND VACCINE IMMUNOLOGY. VOL. 16. ISSUE 1. P. 21 -28 21 68% 46
10 LI, W , YANG, JY , ZHANG, EJ , ZHONG, MH , XIAO, Y , YU, J , ZHOU, DH , CAO, Y , YANG, Y , LI, YM , ET AL (2016) ACTIVATION OF NLRC4 DOWNREGULATES TLR5-MEDIATED ANTIBODY IMMUNE RESPONSES AGAINST FLAGELLIN.CELLULAR & MOLECULAR IMMUNOLOGY. VOL. 13. ISSUE 4. P. 514 -523 25 48% 1

Classes with closest relation at Level 1


Rank Class id link
1 4753 TOLL LIKE RECEPTORS//TLR7//TOLL LIKE RECEPTOR 7
2 8282 BACTERIAL FLAGELLUM//DYNAM NANOMACHINE PROJECT//FLAGELLAR MOTOR
3 23416 INFLAMMAT REGENERAT MED//OCULAR PATHOPHYSIOL//NONA D ARGININE
4 1627 SALMONELLA//SALMONELLA CONTAINING VACUOLE//D BIOL
5 25523 EXPT LUNG//LUNG INFLAMMAT INFECT//PULM CRIT CARE MED INFECT DIS
6 4307 LUCILLE CASTORI MICROBES INFLAMMAT CANC//MUCOSAL IMMUNOLOGY//MICROBIOTA
7 11241 CYSTIC FIBROSIS//INFECT CYST FIBROSIS UNIT//ANTI INFLAMMATORY AGENTS ADMINISTRATION DOSAGE ADVERSE EFFECTS
8 13681 TOLL LIKE RECEPTORS//TOLL LIKE RECEPTOR 9//TLR4
9 9823 PSEUDOMONAS AERUGINOSA//PSEUDOMONAS VACCINE//RD BIOSCI
10 15523 HETEROPHILS//CHICKEN INTERFERON GAMMA//CHICKEN

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