Class information for:
Level 1: MONOCROTALINE//RIGHT VENTRICULAR HYPERTROPHY//MONOCROTALINE PNEUMOTOXICITY

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
21379 421 33.6 63%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
8 4 CARDIAC & CARDIOVASCULAR SYSTEM//PERIPHERAL VASCULAR DISEASES//CARDIOL 1276458
290 3       PULMONARY EMBOLISM//VENOUS THROMBOEMBOLISM//PULMONARY HYPERTENSION 41767
484 2             PULMONARY HYPERTENSION//PULMONARY ARTERIAL HYPERTENSION//CHRONIC THROMBOEMBOLIC PULMONARY HYPERTENSION 15572
21379 1                   MONOCROTALINE//RIGHT VENTRICULAR HYPERTROPHY//MONOCROTALINE PNEUMOTOXICITY 421

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MONOCROTALINE authKW 1052468 18% 19% 76
2 RIGHT VENTRICULAR HYPERTROPHY authKW 189714 5% 12% 22
3 MONOCROTALINE PNEUMOTOXICITY authKW 145059 0% 100% 2
4 PULMONARY HYPERTENSION authKW 83919 20% 1% 85
5 ABT INNERE UMWELT ERKRANKUNGEN address 72530 0% 100% 1
6 AIRWAY LUNG DYSFUNCTION authKW 72530 0% 100% 1
7 ALPHA SYNUCLEIN ASN authKW 72530 0% 100% 1
8 ATRIAL NATRIUREMIC PEPTIDE authKW 72530 0% 100% 1
9 BENJAMIN FRANKLIN MED HOSP address 72530 0% 100% 1
10 CATALYTIC UNIT OF ADENYLATE CYCLASE authKW 72530 0% 100% 1

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Physiology 1512 21% 0% 89
2 Respiratory System 1276 15% 0% 62
3 Pharmacology & Pharmacy 796 27% 0% 113
4 Cardiac & Cardiovascular System 693 17% 0% 71
5 Peripheral Vascular Diseases 450 10% 0% 43
6 Sport Sciences 398 8% 0% 32
7 Toxicology 389 10% 0% 41
8 Medicine, Research & Experimental 170 9% 0% 36
9 Pathology 148 6% 0% 25
10 Critical Care Medicine 19 2% 0% 7

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ABT INNERE UMWELT ERKRANKUNGEN 72530 0% 100% 1
2 BENJAMIN FRANKLIN MED HOSP 72530 0% 100% 1
3 CTEDRA BIOL CELULAR HISTOL 72530 0% 100% 1
4 HLTH SCI MED CARDIOVASC PULM 72530 0% 100% 1
5 HLTH SCI PEDIAT DEV LUNG BIOL 72530 0% 100% 1
6 HOP PEDIAT NEONATOL CIC PEDIAT 72530 0% 100% 1
7 IFR IMAGERIE FONCT 135 MED 72530 0% 100% 1
8 IMAGERIE EXPLORAT FONCT 72530 0% 100% 1
9 INSERM CEDRE 72530 0% 100% 1
10 INSERMU127 572 72530 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 JOURNAL OF APPLIED PHYSIOLOGY 3556 8% 0% 32
2 TOXICOLOGY AND APPLIED PHARMACOLOGY 3554 5% 0% 22
3 EXPERIMENTAL LUNG RESEARCH 2003 2% 0% 7
4 JAPANESE CIRCULATION JOURNAL-ENGLISH EDITION 1429 2% 0% 8
5 AMERICAN REVIEW OF RESPIRATORY DISEASE 1409 3% 0% 11
6 PROCEEDINGS OF THE SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE 1134 2% 0% 8
7 AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY 1126 3% 0% 14
8 BASIC RESEARCH IN CARDIOLOGY 915 1% 0% 6
9 CARDIOVASCULAR RESEARCH 913 2% 0% 10
10 CHINESE JOURNAL OF PHYSIOLOGY 893 1% 0% 3

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 MONOCROTALINE 1052468 18% 19% 76 Search MONOCROTALINE Search MONOCROTALINE
2 RIGHT VENTRICULAR HYPERTROPHY 189714 5% 12% 22 Search RIGHT+VENTRICULAR+HYPERTROPHY Search RIGHT+VENTRICULAR+HYPERTROPHY
3 MONOCROTALINE PNEUMOTOXICITY 145059 0% 100% 2 Search MONOCROTALINE+PNEUMOTOXICITY Search MONOCROTALINE+PNEUMOTOXICITY
4 PULMONARY HYPERTENSION 83919 20% 1% 85 Search PULMONARY+HYPERTENSION Search PULMONARY+HYPERTENSION
5 AIRWAY LUNG DYSFUNCTION 72530 0% 100% 1 Search AIRWAY+LUNG+DYSFUNCTION Search AIRWAY+LUNG+DYSFUNCTION
6 ALPHA SYNUCLEIN ASN 72530 0% 100% 1 Search ALPHA+SYNUCLEIN+ASN Search ALPHA+SYNUCLEIN+ASN
7 ATRIAL NATRIUREMIC PEPTIDE 72530 0% 100% 1 Search ATRIAL+NATRIUREMIC+PEPTIDE Search ATRIAL+NATRIUREMIC+PEPTIDE
8 CATALYTIC UNIT OF ADENYLATE CYCLASE 72530 0% 100% 1 Search CATALYTIC+UNIT+OF+ADENYLATE+CYCLASE Search CATALYTIC+UNIT+OF+ADENYLATE+CYCLASE
9 CENTRAL INSULIN LIKE GROWTH FACTORS 72530 0% 100% 1 Search CENTRAL+INSULIN+LIKE+GROWTH+FACTORS Search CENTRAL+INSULIN+LIKE+GROWTH+FACTORS
10 CIRCULATING GROWTH FACTORS 72530 0% 100% 1 Search CIRCULATING+GROWTH+FACTORS Search CIRCULATING+GROWTH+FACTORS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 SCHULTZE, AE , ROTH, RA , (1998) CHRONIC PULMONARY HYPERTENSION - THE MONOCROTALINE MODEL AND INVOLVEMENT OF THE HEMOSTATIC SYSTEM.JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS. VOL. 1. ISSUE 4. P. 271 -346 101 44% 57
2 HUXTABLE, RJ , (1990) ACTIVATION AND PULMONARY TOXICITY OF PYRROLIZIDINE ALKALOIDS.PHARMACOLOGY & THERAPEUTICS. VOL. 47. ISSUE 3. P. 371-389 60 69% 57
3 WILSON, DW , SEGALL, HJ , PAN, LC , LAME, MW , ESTEP, JE , MORIN, D , (1992) MECHANISMS AND PATHOLOGY OF MONOCROTALINE PULMONARY TOXICITY.CRITICAL REVIEWS IN TOXICOLOGY. VOL. 22. ISSUE 5-6. P. 307-325 36 51% 99
4 CASSIS, L , SHENOY, U , LIPKE, D , BAUGHN, J , FETTINGER, M , GILLESPIE, M , (1997) LUNG ANGIOTENSIN RECEPTOR BINDING CHARACTERISTICS DURING THE DEVELOPMENT OF MONOCROTALINE-INDUCED PULMONARY HYPERTENSION.BIOCHEMICAL PHARMACOLOGY. VOL. 54. ISSUE 1. P. 27-31 20 71% 19
5 HESSEL, MHM , STEENDIJK, P , DEN ADEL, B , SCHUTTE, CI , VAN DER LAARSE, A , (2006) CHARACTERIZATION OF RIGHT VENTRICULAR FUNCTION AFTER MONOCROTALINE-INDUCED PULMONARY HYPERTENSION IN THE INTACT RAT.AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY. VOL. 291. ISSUE 5. P. H2424-H2430 20 48% 58
6 MADDEN, JA , KELLER, PA , EFFROS, RM , SEAVITTE, C , CHOY, JS , HACKER, AD , (1994) RESPONSES TO PRESSURE AND VASOACTIVE AGENTS BY ISOLATED PULMONARY-ARTERIES FROM MONOCROTALINE-TREATED RATS.JOURNAL OF APPLIED PHYSIOLOGY. VOL. 76. ISSUE 4. P. 1589-1593 16 84% 17
7 REINDEL, JF , GANEY, PE , WAGNER, JG , SLOCOMBE, RF , ROTH, RA , (1990) DEVELOPMENT OF MORPHOLOGICAL, HEMODYNAMIC, AND BIOCHEMICAL-CHANGES IN LUNGS OF RATS GIVEN MONOCROTALINE PYRROLE.TOXICOLOGY AND APPLIED PHARMACOLOGY. VOL. 106. ISSUE 2. P. 179-200 17 89% 46
8 KANAI, Y , HORI, S , TANAKA, T , YASUOKA, M , WATANABE, K , AIKAWA, N , HOSODA, Y , (1993) ROLE OF 5-HYDROXYTRYPTAMINE IN THE PROGRESSION OF MONOCROTALINE-INDUCED PULMONARY-HYPERTENSION IN RATS.CARDIOVASCULAR RESEARCH. VOL. 27. ISSUE 9. P. 1619-1623 18 69% 51
9 MOLTENI, A , WARD, WF , TSAO, C , SOLLIDAY, NH , (1988) MONOCROTALINE-INDUCED CARDIOPULMONARY INJURY IN RATS - MODIFIED BY THE NONTHIOL ACE INHIBITORS CGS13945 AND CGS16617.ARCHIVES INTERNATIONALES DE PHARMACODYNAMIE ET DE THERAPIE. VOL. 291. ISSUE . P. 21-40 25 64% 13
10 PAN, LC , WILSON, DW , SEGALL, HJ , (1993) STRAIN DIFFERENCES IN THE RESPONSE OF FISCHER-344 AND SPRAGUE-DAWLEY RATS TO MONOCROTALINE INDUCED PULMONARY VASCULAR-DISEASE.TOXICOLOGY. VOL. 79. ISSUE 1. P. 21-35 17 71% 17

Classes with closest relation at Level 1


Rank Class id link
1 3288 PULMONARY ARTERIAL HYPERTENSION//PULMONARY HYPERTENSION//BMPR2
2 5949 PYRROLIZIDINE ALKALOIDS//COMFREY//SENECIONINE
3 4305 PULMONARY CIRCULATION//HYPOXIC PULMONARY VASOCONSTRICTION//PULMONARY VASCULAR RESISTANCE
4 16038 LUNG METABOLIC FUNCTION//LUNG DRUG UPTAKE//PULMONARY CAPILLARY ENDOTHELIUM
5 30098 ADRENAL GLAND CORTICOSTERONE//BIOCHEMICAL INDICATOR ANALYSIS//CARDIO GREEN
6 28825 CONGENITAL HEART DISEASE WITH LEFT TO RIGHT SHUNT//AND METABOLIC ACIDOSIS AND INBORN METABOLIC ERROR//CARDIAC MEASUREMENT
7 32705 LEUKOCYTE ENDOTHELIAL ADHESIVE INTERACTIONS//ALVEOLAR HYPOXIA//LEUKOCYTE ENDOTHELIAL ADHERENCE
8 8270 PULMONARY HYPERTENSION//COR PULMONALE//MAIN PULMONARY ARTERY DIAMETER
9 1299 PULMONARY ARTERIAL HYPERTENSION//PULMONARY HYPERTENSION//TREPROSTINIL
10 13424 HYPOXIC PULMONARY VASOCONSTRICTION//VOLTAGE DEPENDENT K CHANNEL//OXIDATIVE DNA MODIFICATIONS

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