Class information for:
Level 1: DIPYRONE//METAMIZOL//PIFIR MODEL

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
21214 428 25.3 52%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
11 4 NEUROSCIENCES//CLINICAL NEUROLOGY//NEUROL 1112395
59 3       ANESTHESIOLOGY//PAIN//CHRONIC PAIN 88506
2563 2             TRAMADOL//DIPYRONE//TAPENTADOL 3711
21214 1                   DIPYRONE//METAMIZOL//PIFIR MODEL 428

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 DIPYRONE authKW 2547058 20% 41% 87
2 METAMIZOL authKW 965613 7% 44% 31
3 PIFIR MODEL authKW 411063 3% 52% 11
4 NON OPIOID TOLERANCE authKW 356717 1% 100% 5
5 ANALGIN authKW 351223 2% 62% 8
6 4 METHYLAMINOANTIPYRINE authKW 297262 1% 83% 5
7 ARACHIDONIC ACID AMIDES authKW 142687 0% 100% 2
8 LEUCOGEN authKW 142687 0% 100% 2
9 MORPHINE CROSS TOLERANCE authKW 142687 0% 100% 2
10 NON OPIOID ANALGESIC authKW 142687 0% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Pharmacology & Pharmacy 1616 37% 0% 157
2 Chemistry, Analytical 1037 22% 0% 94
3 Chemistry, Medicinal 153 6% 0% 27
4 Anesthesiology 103 3% 0% 14
5 Medicine, Research & Experimental 68 6% 0% 25
6 Toxicology 49 4% 0% 17
7 Chemistry, Multidisciplinary 47 10% 0% 42
8 Medicine, General & Internal 42 6% 0% 27
9 Neurosciences 42 8% 0% 36
10 Biology 35 3% 0% 14

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 DOLOR ANALGESIA 7 95119 1% 33% 4
2 ABT NEUROGERIATRIE REMOBILISAT 71343 0% 100% 1
3 AQUAT GENET OURCES AQUACULTURAL ECO 71343 0% 100% 1
4 CHAIR GEN BIOORGAN CHEM 71343 0% 100% 1
5 CROMATOG ELETROFO E C ILAR 71343 0% 100% 1
6 ENVIRONM ENGN QUAL 71343 0% 100% 1
7 ESCUELA PREPARATORIA MELCHOR OCAMPO 71343 0% 100% 1
8 GLOBAL DRUG SURVEILLANCE PHARMACOEPIDEMIOL 71343 0% 100% 1
9 MOL CHARACTERIZAT BIOMOL 71343 0% 100% 1
10 NACL MED NUTR SALVADOR SUBIRAN INVEST 71343 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 INVESTIGACION MEDICA INTERNACIONAL 12818 1% 4% 4
2 EGYPTIAN JOURNAL OF GENETICS AND CYTOLOGY 6200 0% 4% 2
3 JOURNAL OF ANALYTICAL CHEMISTRY 4572 4% 0% 17
4 DRUG DEVELOPMENT RESEARCH 2408 2% 0% 10
5 BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH 1742 3% 0% 12
6 EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY 1688 3% 0% 13
7 CHEMIA ANALITYCZNA 1347 2% 0% 7
8 ARCHIV FUR EXPERIMENTELLE VETERINARMEDIZIN 1069 1% 0% 4
9 EUROPEAN JOURNAL OF PHARMACOLOGY 710 4% 0% 17
10 MICROCHEMICAL JOURNAL 580 1% 0% 6

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 DIPYRONE 2547058 20% 41% 87 Search DIPYRONE Search DIPYRONE
2 METAMIZOL 965613 7% 44% 31 Search METAMIZOL Search METAMIZOL
3 PIFIR MODEL 411063 3% 52% 11 Search PIFIR+MODEL Search PIFIR+MODEL
4 NON OPIOID TOLERANCE 356717 1% 100% 5 Search NON+OPIOID+TOLERANCE Search NON+OPIOID+TOLERANCE
5 ANALGIN 351223 2% 62% 8 Search ANALGIN Search ANALGIN
6 4 METHYLAMINOANTIPYRINE 297262 1% 83% 5 Search 4+METHYLAMINOANTIPYRINE Search 4+METHYLAMINOANTIPYRINE
7 ARACHIDONIC ACID AMIDES 142687 0% 100% 2 Search ARACHIDONIC+ACID+AMIDES Search ARACHIDONIC+ACID+AMIDES
8 LEUCOGEN 142687 0% 100% 2 Search LEUCOGEN Search LEUCOGEN
9 MORPHINE CROSS TOLERANCE 142687 0% 100% 2 Search MORPHINE+CROSS+TOLERANCE Search MORPHINE+CROSS+TOLERANCE
10 NON OPIOID ANALGESIC 142687 0% 100% 2 Search NON+OPIOID+ANALGESIC Search NON+OPIOID+ANALGESIC

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 NIKOLOVA, I , TENCHEVA, J , VOINIKOV, J , PETKOVA, V , BENBASAT, N , DANCHEV, N , (2012) METAMIZOLE: A REVIEW PROFILE OF A WELL-KNOWN "FORGOTTEN" DRUG. PART I: PHARMACEUTICAL AND NONCLINICAL PROFILE.BIOTECHNOLOGY & BIOTECHNOLOGICAL EQUIPMENT. VOL. 26. ISSUE 6. P. 3329-3337 58 64% 13
2 HERNANDEZ-DELGADILLO, GP , CRUZ, SL , (2006) ENDOGENOUS OPIOIDS ARE INVOLVED IN MORPHINE AND DIPYRONE ANALGESIC POTENTIATION IN THE TAIL FLICK TEST IN RATS.EUROPEAN JOURNAL OF PHARMACOLOGY. VOL. 546. ISSUE 1-3. P. 54-59 23 85% 22
3 RUMIN, M , SMAJDOR, J , PACZOSA-BATOR, B , PIECH, R , (2016) VOLTAMMETRY AND FLOW INJECTION ANALYSIS WITH AMPEROMETRIC DETECTION FOR SENSITIVE SODIUM METAMIZOLE DETERMINATION ON GLASSY CARBON ELECTRODE MODIFIED WITH SWCNTS/NAFION.ECS JOURNAL OF SOLID STATE SCIENCE AND TECHNOLOGY. VOL. 5. ISSUE 8. P. M3005 -M3011 18 82% 0
4 JASIECKA, A , MASLANKA, T , JAROSZEWSKI, JJ , (2014) PHARMACOLOGICAL CHARACTERISTICS OF METAMIZOLE.POLISH JOURNAL OF VETERINARY SCIENCES. VOL. 17. ISSUE 1. P. 207-214 25 54% 4
5 LEVY, M , ZYLBERKATZ, E , ROSENKRANZ, B , (1995) CLINICAL PHARMACOKINETICS OF DIPYRONE AND ITS METABOLITES.CLINICAL PHARMACOKINETICS. VOL. 28. ISSUE 3. P. 216-234 27 75% 101
6 LOPEZ-MUNOZ, FJ , GODINEZ-CHAPARRO, B , HUERTA-CRUZ, JC , GUEVARA-LOPEZ, U , DOMINGUEZ-RAMIREZ, AM , CORTES-ARROYO, AR , (2008) THE ANTINOCICEPTIVE EFFICACY OF MORPHINE, METAMIZOL, OR THEIR COMBINATION IN AN EXPERIMENTAL RAT MODEL WITH DIFFERENT LEVELS OF INFLAMMATORY PAIN.PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR. VOL. 91. ISSUE 1. P. 196-201 21 70% 3
7 MORENO-ROCHA, LA , LOPEZ-MUNOZ, FJ , MEDINA-LOPEZ, JR , DOMINGUEZ-RAMIREZ, AM , (2016) EFFECT OF TRAMADOL ON METAMIZOL PHARMACOKINETICS AND PHARMACODYNAMICS AFTER SINGLE AND REPEATED ADMINISTRATIONS IN ARTHRITIC RATS.SAUDI PHARMACEUTICAL JOURNAL. VOL. 24. ISSUE 6. P. 674 -684 15 75% 0
8 GAN, XJ , LIU, SP , LIU, ZF , WANG, YQ , CUI, ZP , HU, XL , (2012) FLUORESCENCE QUENCHING METHOD FOR THE DETERMINATION OF ANALGIN AND METABOLIN WITH SOME AROMATIC AMINO ACIDS AS PROBES.ACTA CHIMICA SINICA. VOL. 70. ISSUE 1. P. 58 -64 13 93% 2
9 LAMPL, C , LIKAR, R , (2014) METAMIZOLE (DIPYRONE): MODE OF ACTION, DRUG-DRUG INTERACTIONS, AND RISK OF AGRANULOCYTOSIS.SCHMERZ. VOL. 28. ISSUE 6. P. 584 -+ 18 60% 1
10 MARCOLINO, LH , BONIFACIO, VG , FATIBELLO-FILHO, O , TEIXEIRA, MFS , (2005) FLOW INJECTION TURBIDIMETRIC DETERMINATION OF DIPYRONE USING A SOLID-PHASE REACTOR CONTAINING SILVER CHLORIDE IMMOBILIZED IN A POLYESTER RESIN..QUIMICA NOVA. VOL. 28. ISSUE 5. P. 783-787 17 77% 12

Classes with closest relation at Level 1


Rank Class id link
1 17750 PHARMACOL PROGRAM//ALGESIOMETRIC TESTS//BRAIN SEROTONIN RECEPTORS
2 16177 AGRANULOCYTOSIS//DRUG INDUCED AGRANULOCYTOSIS//EVALUATION SCORE
3 17600 INTRAVENOUS ACETAMINOPHEN//PARACETAMOL//PROPACETAMOL
4 31737 2 HYDROXY 5 METHOXYBENZOIC ACID//4 HYDROXY OXYPHENBUTAZONE//ANTIPYRINE DERIVATIVES PHARMACOLOGY SYNTHESIS
5 7455 PARACETAMOL//METHOCARBAMOL//ACETAMINOPHEN
6 9386 PAIN NUFFIELD ANAESTHET//THIRD MOLAR SURGERY//DENTAL PAIN
7 35783 PANTOTHENOL//DEXPANTHENOL//CARBOXYVINYL POLYMERS
8 36227 ORAL PHARMACOL THER EUT//1 3 BISELECTROPHILES//AMPICILLIN BINDING
9 37077 INJECTION SOLVENT//ALVEOLAR MACROPHAGE GUINEA PIG//ANALYTE SOLVENT
10 14997 GRP NEUROFARMACOL MOL//PERIPHERAL ANTINOCICEPTION//ANTINOCICEPTION

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