Class information for:
Level 1: EFAROXAN//CELLULAR PHARMACOL GRP//IMIDAZOLINE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
20381 463 30.6 61%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
297 3       DIABETES//ISLET TRANSPLANTATION//BETA CELL 41297
457 2             BETA CELL//INSULIN SECRETION//PANCREATIC ISLETS 16005
20381 1                   EFAROXAN//CELLULAR PHARMACOL GRP//IMIDAZOLINE 463

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 EFAROXAN authKW 755603 6% 44% 26
2 CELLULAR PHARMACOL GRP address 586601 3% 68% 13
3 IMIDAZOLINE authKW 490226 12% 13% 57
4 KU14R authKW 211039 1% 80% 4
5 CAS 66529 17 7 authKW 197850 1% 100% 3
6 DERIGLIDOLE authKW 197850 1% 100% 3
7 DG 5128 authKW 197850 1% 100% 3
8 S 22068 authKW 197850 1% 100% 3
9 SL 840418 authKW 197850 1% 100% 3
10 IMIDAZOLINE COMPOUNDS authKW 197844 1% 50% 6

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Pharmacology & Pharmacy 2154 40% 0% 187
2 Endocrinology & Metabolism 1766 24% 0% 113
3 Physiology 307 10% 0% 45
4 Biochemistry & Molecular Biology 92 16% 0% 74
5 Biophysics 80 6% 0% 27
6 Chemistry, Medicinal 76 5% 0% 21
7 Medicine, Research & Experimental 73 6% 0% 27
8 Cell Biology 54 8% 0% 35
9 Chemistry, Organic 10 4% 0% 18
10 Engineering, Ocean 1 0% 0% 1

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CELLULAR PHARMACOL GRP 586601 3% 68% 13
2 BIOL SCI CELLULAR PHARMACOL GRP 131900 0% 100% 2
3 BELOZERSKY PHYSICOCHEM BIO 65950 0% 100% 1
4 BIOL SCIQUEENS MED 65950 0% 100% 1
5 COMPLEMENTARY MED MED 65950 0% 100% 1
6 INTERGRATED PHYSIOL 65950 0% 100% 1
7 MED MITAKA 65950 0% 100% 1
8 MED PHARMACOL AVE CAMPO CHARRO SN 65950 0% 100% 1
9 NUTR PHSYIOL CHEM 65950 0% 100% 1
10 ROLF LUFT DIABET ENDOCRIONL 65950 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 EUROPEAN JOURNAL OF PHARMACOLOGY 4114 9% 0% 42
2 DIABETES 3141 5% 0% 24
3 NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 2431 3% 0% 15
4 BRITISH JOURNAL OF PHARMACOLOGY 1774 5% 0% 22
5 JOURNAL OF PHARMACOBIO-DYNAMICS 1003 1% 0% 5
6 JOURNAL OF MOLECULAR ENDOCRINOLOGY 781 1% 0% 5
7 ARCHIVUM HISTOLOGICUM JAPONICUM 765 0% 1% 2
8 JAPANESE JOURNAL OF PHARMACOLOGY 726 2% 0% 7
9 BIOSCIENCE REPORTS 701 1% 0% 5
10 ACTA PHYSIOLOGICA SCANDINAVICA 581 2% 0% 7

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 EFAROXAN 755603 6% 44% 26 Search EFAROXAN Search EFAROXAN
2 IMIDAZOLINE 490226 12% 13% 57 Search IMIDAZOLINE Search IMIDAZOLINE
3 KU14R 211039 1% 80% 4 Search KU14R Search KU14R
4 CAS 66529 17 7 197850 1% 100% 3 Search CAS+66529+17+7 Search CAS+66529+17+7
5 DERIGLIDOLE 197850 1% 100% 3 Search DERIGLIDOLE Search DERIGLIDOLE
6 DG 5128 197850 1% 100% 3 Search DG+5128 Search DG+5128
7 S 22068 197850 1% 100% 3 Search S+22068 Search S+22068
8 SL 840418 197850 1% 100% 3 Search SL+840418 Search SL+840418
9 IMIDAZOLINE COMPOUNDS 197844 1% 50% 6 Search IMIDAZOLINE+COMPOUNDS Search IMIDAZOLINE+COMPOUNDS
10 BL11282 87932 0% 67% 2 Search BL11282 Search BL11282

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 STADLBAUER, K , LEHNER, Z , STAMENKOVIC, N , RUSTENBECK, I , SURMAN, L , LUGER, A , FURNSINN, C , (2014) DISSECTION OF MECHANISMS THAT ACCOUNT FOR IMIDAZOLINE-INDUCED LOWERING OF BLOOD GLUCOSE IN MICE.EUROPEAN JOURNAL OF PHARMACOLOGY. VOL. 741. ISSUE . P. 178 -185 23 88% 0
2 LEHNER, Z , STADLBAUER, K , ADORJAN, I , RUSTENBECK, I , BELZ, M , FENZL, A , DE CILLIA, VAM , GRUBER, D , BAUER, L , FROBEL, K , ET AL (2012) MECHANISMS OF ANTIHYPERGLYCAEMIC ACTION OF EFAROXAN IN MICE: TIME FOR REAPPRAISAL OF ALPHA(2A)-ADRENERGIC ANTAGONISM IN THE TREATMENT OF TYPE 2 DIABETES?.DIABETOLOGIA. VOL. 55. ISSUE 11. P. 3071 -3082 29 71% 1
3 MORGAN, NG , CHAN, SLF , MOURTADA, M , MONKS, LK , RAMSDEN, CA , (1999) IMIDAZOLINES AND PANCREATIC HORMONE SECRETION.IMIDAZOLINE RECEPTORS AND THEIR ENDOGENOUS LIGANDS. VOL. 881. ISSUE . P. 217-228 28 82% 45
4 FAGERHOLM, V , SCHEININ, M , HAAPARANTA, M , (2008) ALPHA(2A)-ADRENOCEPTOR ANTAGONISM INCREASES INSULIN SECRETION AND SYNERGISTICALLY AUGMENTS THE INSULINOTROPIC EFFECT OF GLIBENCLAMIDE IN MICE.BRITISH JOURNAL OF PHARMACOLOGY. VOL. 154. ISSUE 6. P. 1287 -1296 32 57% 13
5 MOURTADA, M , CHAN, SLF , SMITH, SA , MORGAN, NG , (1999) MULTIPLE EFFECTOR PATHWAYS REGULATE THE INSULIN SECRETORY RESPONSE TO THE IMIDAZOLINE RX871024 IN ISOLATED RAT PANCREATIC ISLETS.BRITISH JOURNAL OF PHARMACOLOGY. VOL. 127. ISSUE 5. P. 1279 -1287 27 75% 9
6 MAYER, G , TABERNER, PV , (2002) EFFECTS OF THE IMIDAZOLINE LIGANDS EFAROXAN AND KU14R ON BLOOD GLUCOSE HOMEOSTASIS IN THE MOUSE.EUROPEAN JOURNAL OF PHARMACOLOGY. VOL. 454. ISSUE 1. P. 95-102 21 81% 14
7 DEVEDJIAN, JC , PUJOL, A , CAYLA, C , GEORGE, M , CASELLAS, A , PARIS, H , BOSCH, F , (2000) TRANSGENIC MICE OVEREXPRESSING ALPHA(2A)-ADRENOCEPTORS IN PANCREATIC BETA-CELLS SHOW ALTERED REGULATION OF GLUCOSE HOMEOSTASIS.DIABETOLOGIA. VOL. 43. ISSUE 7. P. 899 -906 25 66% 44
8 BLECK, C , WIENBERGEN, A , RUSTENBECK, I , (2005) ESSENTIAL ROLE OF THE IMIDAZOLINE MOIETY IN THE INSULINOTROPIC EFFECT BUT NOT THE K-ATP CHANNEL-BLOCKING EFFECT OF IMIDAZOLINES; A COMPARISON OF THE EFFECTS OF EFAROXAN AND ITS IMIDAZOLE ANALOGUE, KU14R.DIABETOLOGIA. VOL. 48. ISSUE 12. P. 2567-2575 21 64% 14
9 HATLAPATKA, K , WIENBERGEN, A , KUHNE, C , JORNS, A , WILLENBORG, M , RUSTENBECK, I , (2009) SELECTIVE ENHANCEMENT OF NUTRIENT-INDUCED INSULIN SECRETION BY ATP-SENSITIVE K+ CHANNEL-BLOCKING IMIDAZOLINES.JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. VOL. 331. ISSUE 3. P. 1033-1041 21 57% 2
10 CHAN, SLF , PALLETT, AL , CLEWS, J , RAMSDEN, CA , CHAPMAN, JC , KANE, C , DUNNE, MJ , MORGAN, NG , (1998) CHARACTERISATION OF NEW EFAROXAN DERIVATIVES FOR USE IN PURIFICATION OF IMIDAZOLINE-BINDING SITES.EUROPEAN JOURNAL OF PHARMACOLOGY. VOL. 355. ISSUE 1. P. 67-76 23 70% 14

Classes with closest relation at Level 1


Rank Class id link
1 11202 INSULIN SECRETION//TIME DEPENDENT SUPPRESSION//MOL MED L6 01BENDOCRINE DIABET UNIT
2 5229 AGMATINE//IMIDAZOLINE RECEPTORS//MOXONIDINE
3 31316 ADENOSINE 5 O 2 THIODIPHOSPHATE ADP BETA S//UNIT UP EA 1677//2 METHYLTHIOADENOSINE
4 4911 PULSATILE INSULIN SECRETION//PANCREATIC BETA CELL//UNITE ENDOCRINOL METAB
5 27091 EYE CHAMBER//SAN DIEGO MICROSURG//PANCREATIC INNERVATION
6 4912 D GLUCOSE METABOLISM//CHILDRENS DIABET//PANCREATIC ISLETS
7 22680 GK RAT//INSULIN GLUCOSE CLAMP//PHOSPHORYLATIVE SYSTEM
8 28963 TREATING COMMUNICATION DISORDERS//AFFILIATIVE AROUSAL//AGING EMPLOYEES
9 9490 ALPHA2 ADRENOCEPTOR SUBTYPES//ALPHA2C ADRENOCEPTOR//ALPHA2A ADRENOCEPTOR
10 29175 ISLET BLOOD FLOW//PANCREATIC BLOOD FLOW//ISLET BLOOD PERFUSION

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