Class information for:
Level 1: LYNCH SYNDROME//MICROSATELLITE INSTABILITY//HNPCC

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
201 3943 38.2 90%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
6 4 GASTROENTEROLOGY & HEPATOLOGY//ONCOLOGY//SURGERY 1371034
109 3       RECTAL CANCER//COLORECTAL CANCER//COLONOSCOPY 71522
1071 2             LYNCH SYNDROME//MICROSATELLITE INSTABILITY//HNPCC 9941
201 1                   LYNCH SYNDROME//MICROSATELLITE INSTABILITY//HNPCC 3943

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 LYNCH SYNDROME authKW 3547131 16% 73% 627
2 MICROSATELLITE INSTABILITY authKW 2842869 22% 43% 850
3 HNPCC authKW 2232400 10% 71% 404
4 HEREDITARY NONPOLYPOSIS COLORECTAL CANCER authKW 1604417 7% 72% 289
5 MLH1 authKW 881380 5% 54% 211
6 MSH2 authKW 666275 4% 52% 167
7 HMLH1 authKW 592281 4% 53% 144
8 HMSH2 authKW 589371 3% 64% 119
9 MISMATCH REPAIR authKW 574179 7% 28% 262
10 MISMATCH REPAIR GENES authKW 557425 3% 67% 107

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Oncology 34255 48% 0% 1902
2 Genetics & Heredity 9980 22% 0% 857
3 Gastroenterology & Hepatology 8100 14% 0% 563
4 Pathology 5051 11% 0% 420
5 Surgery 728 9% 0% 372
6 Obstetrics & Gynecology 435 4% 0% 157
7 Medicine, Research & Experimental 111 3% 0% 127
8 Medicine, General & Internal 83 4% 0% 156
9 Cell Biology 77 4% 0% 177
10 Medical Laboratory Technology 75 1% 0% 39

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 DANISH HNPCC REGISTER 114017 0% 82% 18
2 NETHERLANDS FDN DETECT HEREDITARY TUMOURS 101260 1% 59% 22
3 ONCOL SPERIMENTALE 1 64516 0% 83% 10
4 HNPCC REGISTER 63217 0% 58% 14
5 FAMILIAL GASTROINTESTINAL CANC REGISTRY 62693 0% 45% 18
6 NEW ZEALAND FAMILIAL GASTROINTESTINAL CANC REGIST 62449 0% 73% 11
7 HEREDITARY GASTROINTESTINAL CANC REGISTRY 55297 0% 71% 10
8 U434 47953 1% 20% 31
9 COLORECTAL MED GENET 42973 0% 29% 19
10 GRP HUMAN GENET 36014 0% 29% 16

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 FAMILIAL CANCER 274119 4% 20% 176
2 HEREDITARY CANCER IN CLINICAL PRACTICE 35728 1% 16% 29
3 HUMAN MUTATION 10570 2% 2% 74
4 GENES CHROMOSOMES & CANCER 7039 1% 2% 54
5 JOURNAL OF MOLECULAR DIAGNOSTICS 6472 1% 3% 31
6 INTERNATIONAL JOURNAL OF CANCER 6109 3% 1% 128
7 JOURNAL OF MEDICAL GENETICS 5549 2% 1% 65
8 GASTROENTEROLOGY 4932 2% 1% 93
9 CLINICAL GENETICS 4679 1% 1% 56
10 CANCER RESEARCH 4073 4% 0% 147

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 LYNCH SYNDROME 3547131 16% 73% 627 Search LYNCH+SYNDROME Search LYNCH+SYNDROME
2 MICROSATELLITE INSTABILITY 2842869 22% 43% 850 Search MICROSATELLITE+INSTABILITY Search MICROSATELLITE+INSTABILITY
3 HNPCC 2232400 10% 71% 404 Search HNPCC Search HNPCC
4 HEREDITARY NONPOLYPOSIS COLORECTAL CANCER 1604417 7% 72% 289 Search HEREDITARY+NONPOLYPOSIS+COLORECTAL+CANCER Search HEREDITARY+NONPOLYPOSIS+COLORECTAL+CANCER
5 MLH1 881380 5% 54% 211 Search MLH1 Search MLH1
6 MSH2 666275 4% 52% 167 Search MSH2 Search MSH2
7 HMLH1 592281 4% 53% 144 Search HMLH1 Search HMLH1
8 HMSH2 589371 3% 64% 119 Search HMSH2 Search HMSH2
9 MISMATCH REPAIR 574179 7% 28% 262 Search MISMATCH+REPAIR Search MISMATCH+REPAIR
10 MISMATCH REPAIR GENES 557425 3% 67% 107 Search MISMATCH+REPAIR+GENES Search MISMATCH+REPAIR+GENES

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 COLAS, C , COULET, F , SVRCEK, M , COLLURA, A , FLEJOU, JF , DUVAL, A , HAMELIN, R , (2012) LYNCH OR NOT LYNCH? IS THAT ALWAYS A QUESTION?.ADVANCES IN CANCER RESEARCH, VOL 113. VOL. 113. ISSUE . P. 121-166 185 84% 14
2 GIARDIELLO, FM , ALLEN, JI , AXILBUND, JE , BOLAND, CR , BURKE, CA , BURT, RW , CHURCH, JM , DOMINITZ, JA , JOHNSON, DA , KALTENBACH, T , ET AL (2014) GUIDELINES ON GENETIC EVALUATION AND MANAGEMENT OF LYNCH SYNDROME: A CONSENSUS STATEMENT BY THE US MULTI-SOCIETY TASK FORCE ON COLORECTAL CANCERE.AMERICAN JOURNAL OF GASTROENTEROLOGY. VOL. 109. ISSUE 8. P. 1159 -1179 115 85% 53
3 GIARDIELLO, FM , ALLEN, JI , AXILBUND, JE , BOLAND, CR , BURKE, CA , BURT, RW , CHURCH, JM , DOMINITZ, JA , JOHNSON, DA , KALTENBACH, T , ET AL (2014) GUIDELINES ON GENETIC EVALUATION AND MANAGEMENT OF LYNCH SYNDROME: A CONSENSUS STATEMENT BY THE US MULTI-SOCIETY TASK FORCE ON COLORECTAL CANCER.GASTROENTEROLOGY. VOL. 147. ISSUE 2. P. 502 -526 116 85% 46
4 BUZA, N , ZIAI, J , HUI, P , (2016) MISMATCH REPAIR DEFICIENCY TESTING IN CLINICAL PRACTICE.EXPERT REVIEW OF MOLECULAR DIAGNOSTICS. VOL. 16. ISSUE 5. P. 591 -604 138 87% 0
5 LADABAUM, U , FORD, JM , MARTEL, M , BARKUN, AN , (2015) AMERICAN GASTROENTEROLOGICAL ASSOCIATION TECHNICAL REVIEW ON THE DIAGNOSIS AND MANAGEMENT OF LYNCH SYNDROME.GASTROENTEROLOGY. VOL. 149. ISSUE 3. P. 783 -+ 124 86% 4
6 LYNCH, HT , SNYDER, CL , SHAW, TG , HEINEN, CD , HITCHINS, MP , (2015) MILESTONES OF LYNCH SYNDROME: 1895-2015.NATURE REVIEWS CANCER. VOL. 15. ISSUE 3. P. 181 -194 115 65% 31
7 SIJMONS, RH , HOFSTRA, RMW , (2016) REVIEW: CLINICAL ASPECTS OF HEREDITARY DNA MISMATCH REPAIR GENE MUTATIONS.DNA REPAIR. VOL. 38. ISSUE . P. 155 -162 82 90% 6
8 GIARDIELLO, FM , ALLEN, JI , AXILBUND, JE , BOLAND, CR , BURKE, CA , BURT, RW , CHURCH, JM , DOMINITZ, JA , JOHNSON, DA , KALTENBACH, T , ET AL (2014) GUIDELINES ON GENETIC EVALUATION AND MANAGEMENT OF LYNCH SYNDROME: A CONSENSUS STATEMENT BY THE US MULTI-SOCIETY TASK FORCE ON COLORECTAL CANCER.DISEASES OF THE COLON & RECTUM. VOL. 57. ISSUE 8. P. 1025 -1048 115 84% 14
9 HUXLEY, N , HOYLE, M , JONES-HUGHES, T , COELHO, H , COOPER, C , FRAYLING, I , HYDE, C , SNOWSILL, T , (2014) A SYSTEMATIC REVIEW AND ECONOMIC EVALUATION OF DIAGNOSTIC STRATEGIES FOR LYNCH SYNDROME.HEALTH TECHNOLOGY ASSESSMENT. VOL. 18. ISSUE 58. P. 1 -+ 135 63% 25
10 GIARDIELLO, FM , ALLEN, JI , AXILBUND, JE , BOLAND, CR , BURKE, CA , BURT, RW , CHURCH, JM , DOMINITZ, JA , JOHNSON, DA , KALTENBACH, T , ET AL (2014) GUIDELINES ON GENETIC EVALUATION AND MANAGEMENT OF LYNCH SYNDROME: A CONSENSUS STATEMENT BY THE U.S. MULTI-SOCIETY TASK FORCE ON COLORECTAL CANCER.GASTROINTESTINAL ENDOSCOPY. VOL. 80. ISSUE 2. P. 197 -220 115 84% 8

Classes with closest relation at Level 1


Rank Class id link
1 4599 MISMATCH REPAIR//MUTS//DNA MISMATCH REPAIR
2 5374 FAMILIAL ADENOMATOUS POLYPOSIS//APC GENE//MUTYH
3 9828 SERRATED ADENOMA//SESSILE SERRATED ADENOMA//HYPERPLASTIC POLYP
4 15816 DCC GENE//BIOPHYS CYTOMETRY//DCC
5 12234 GASTRIC CANCER//MICROSATELLITE INSTABILITY//HUMAN GASTRIC MUCIN
6 9911 MUCINOUS HISTOLOGY//MUCINOUS ADENOCARCINOMA//PROXIMAL SHIFT
7 13169 SEBACEOUS CARCINOMA//MUIR TORRE SYNDROME//SEBACEOMA
8 29607 SYNCHRONOUS PRIMARY CANCERS//SYNCHRONOUS CARCINOMA//SYNCHRONOUS PRIMARY CANCER
9 23203 HEREDITARY DIFFUSE GASTRIC CANCER//PROPHYLACTIC GASTRECTOMY//HDGC
10 27700 JOINT SERV BIOMARKER EVALUAT ONCOL//KI67 SCORE//LOCDIR

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