Class information for:
Level 1: INDOLE 3 CARBINOL//3 3 DIINDOLYLMETHANE//DIINDOLYLMETHANE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
17382 602 42.6 83%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
468 3       GLUCOSINOLATES//BILIRUBIN//HEME OXYGENASE 24157
2122 2             GLUCOSINOLATES//SULFORAPHANE//ISOTHIOCYANATES 5091
17382 1                   INDOLE 3 CARBINOL//3 3 DIINDOLYLMETHANE//DIINDOLYLMETHANE 602

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 INDOLE 3 CARBINOL authKW 4175332 23% 60% 137
2 3 3 DIINDOLYLMETHANE authKW 2016919 9% 76% 52
3 DIINDOLYLMETHANE authKW 634000 4% 50% 25
4 I3C authKW 521708 2% 86% 12
5 INDOLE 3 CARBINOL I3C authKW 384410 2% 63% 12
6 3 3 DIINDOLYLMETHANE DIM authKW 316031 1% 69% 9
7 OSU A9 authKW 202888 1% 100% 4
8 DAVID ALICE JURIST address 202884 1% 67% 6
9 DIM authKW 190471 2% 29% 13
10 3 DIINDOLYLMETHANE authKW 135256 1% 67% 4

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Oncology 3161 38% 0% 229
2 Toxicology 1367 15% 0% 89
3 Nutrition & Dietetics 456 8% 0% 47
4 Pharmacology & Pharmacy 447 18% 0% 108
5 Food Science & Technology 149 7% 0% 41
6 Chemistry, Medicinal 123 5% 0% 30
7 Biochemistry & Molecular Biology 90 15% 0% 88
8 Medicine, Research & Experimental 47 4% 0% 27
9 Endocrinology & Metabolism 37 4% 0% 26
10 Cell Biology 28 6% 0% 34

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 DAVID ALICE JURIST 202884 1% 67% 6
2 NUTR SCI TOXICOL 74656 5% 5% 30
3 BLOOD BIOPHARMACEUT VIRAL DETECT 67628 0% 67% 2
4 DAVID ALICE JURIST MED 67628 0% 67% 2
5 BIOCHEM CANC STUDIES 50722 0% 100% 1
6 BIOORGAN CHEM PHARMACEUT UNIT 50722 0% 100% 1
7 DEARPARTMANT TOXICOL 50722 0% 100% 1
8 DEP BIOCHEM MOL GENET 50722 0% 100% 1
9 ENDOCRINOL DIABET METAB DAD 50722 0% 100% 1
10 ENVIRONM MOL TOXICOL MARINE 50722 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CARCINOGENESIS 5024 6% 0% 34
2 CANCER PREVENTION RESEARCH 4131 2% 1% 10
3 FOOD AND CHEMICAL TOXICOLOGY 3150 4% 0% 23
4 NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL 1509 1% 0% 9
5 BIOCHEMICAL PHARMACOLOGY 1298 4% 0% 22
6 CHEMICO-BIOLOGICAL INTERACTIONS 1274 2% 0% 12
7 CANCER LETTERS 1188 3% 0% 17
8 JOURNAL OF NUTRITION 962 3% 0% 16
9 JOURNAL OF NUTRITIONAL BIOCHEMISTRY 759 1% 0% 7
10 ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY 755 1% 0% 4

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 INDOLE 3 CARBINOL 4175332 23% 60% 137 Search INDOLE+3+CARBINOL Search INDOLE+3+CARBINOL
2 3 3 DIINDOLYLMETHANE 2016919 9% 76% 52 Search 3+3+DIINDOLYLMETHANE Search 3+3+DIINDOLYLMETHANE
3 DIINDOLYLMETHANE 634000 4% 50% 25 Search DIINDOLYLMETHANE Search DIINDOLYLMETHANE
4 I3C 521708 2% 86% 12 Search I3C Search I3C
5 INDOLE 3 CARBINOL I3C 384410 2% 63% 12 Search INDOLE+3+CARBINOL+I3C Search INDOLE+3+CARBINOL+I3C
6 3 3 DIINDOLYLMETHANE DIM 316031 1% 69% 9 Search 3+3+DIINDOLYLMETHANE+DIM Search 3+3+DIINDOLYLMETHANE+DIM
7 OSU A9 202888 1% 100% 4 Search OSU+A9 Search OSU+A9
8 DIM 190471 2% 29% 13 Search DIM Search DIM
9 3 DIINDOLYLMETHANE 135256 1% 67% 4 Search 3+DIINDOLYLMETHANE Search 3+DIINDOLYLMETHANE
10 TETRAHYDROINDENOINDOLE 114123 0% 75% 3 Search TETRAHYDROINDENOINDOLE Search TETRAHYDROINDENOINDOLE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 AGGARWAL, BB , ICHIKAWA, H , (2005) MOLECULAR TARGETS AND ANTICANCER POTENTIAL OF INDOLE-3-CARBINOL AND ITS DERIVATIVES.CELL CYCLE. VOL. 4. ISSUE 9. P. 1201-1215 96 78% 215
2 AHMAD, A , SAKR, WA , RAHMAN, KMW , (2010) ANTICANCER PROPERTIES OF INDOLE COMPOUNDS: MECHANISM OF APOPTOSIS INDUCTION AND ROLE IN CHEMOTHERAPY.CURRENT DRUG TARGETS. VOL. 11. ISSUE 6. P. 652-666 118 58% 46
3 WENG, JR , TSAI, CH , KULP, SK , CHEN, CS , (2008) INDOLE-3-CARBINOL AS A CHEMOPREVENTIVE AND ANTI-CANCER AGENT.CANCER LETTERS. VOL. 262. ISSUE 2. P. 153-163 75 74% 120
4 BANERJEE, S , KONG, DJ , WANG, ZW , BAO, B , HILLMAN, GG , SARKAR, FH , (2011) ATTENUATION OF MULTI-TARGETED PROLIFERATION-LINKED SIGNALING BY 3,3 '-DIINDOLYLMETHANE (DIM): FROM BENCH TO CLINIC.MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH. VOL. 728. ISSUE 1-2. P. 47 -66 73 55% 40
5 WENG, JR , OMAR, HA , KULP, K , CHEN, CS , (2010) PHARMACOLOGICAL EXPLOITATION OF INDOLE-3-CARBINOL TO DEVELOP POTENT ANTITUMOR AGENTS.MINI-REVIEWS IN MEDICINAL CHEMISTRY. VOL. 10. ISSUE 5. P. 398-404 56 74% 16
6 SAFE, S , PAPINENI, S , CHINTHARLAPALLI, S , (2008) CANCER CHEMOTHERAPY WITH INDOLE-3-CARBINOL, BIS(3 '-INDOLYL)METHANE AND SYNTHETIC ANALOGS.CANCER LETTERS. VOL. 269. ISSUE 2. P. 326-338 66 53% 124
7 NGUYEN, HH , LAVRENOV, SN , SUNDAR, SN , NGUYEN, DHH , TSENG, M , MARCONETT, CN , KUNG, J , STAUB, RE , PREOBRAZHENSKAYA, MN , BJELDANES, LF , ET AL (2010) 1-BENZYL-INDOLE-3-CARBINOL IS A NOVEL INDOLE-3-CARBINOL DERIVATIVE WITH SIGNIFICANTLY ENHANCED POTENCY OF ANTI-PROLIFERATIVE AND ANTI-ESTROGENIC PROPERTIES IN HUMAN BREAST CANCER CELLS.CHEMICO-BIOLOGICAL INTERACTIONS. VOL. 186. ISSUE 3. P. 255-266 35 83% 13
8 ANDERTON, MJ , MANSON, MM , VERSCHOYLE, RD , GESCHER, A , LAMB, JH , FARMER, PB , STEWARD, WP , WILLIAMS, ML , (2004) PHARMACOKINETICS AND TISSUE DISPOSITION OF INDOLE-3-CARBINOL AND ITS ACID CONDENSATION PRODUCTS AFTER ORAL ADMINISTRATION TO MICE.CLINICAL CANCER RESEARCH. VOL. 10. ISSUE 15. P. 5233-5241 33 83% 108
9 AHMAD, A , BIERSACK, B , LI, YW , KONG, DJ , BAO, B , SCHOBERT, R , PADHYE, SB , SARKAR, FH , (2013) TARGETED REGULATION OF PI3K/AKT/MTOR/NF-KAPPA B SIGNALING BY INDOLE COMPOUNDS AND THEIR DERIVATIVES: MECHANISTIC DETAILS AND BIOLOGICAL IMPLICATIONS FOR CANCER THERAPY.ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY. VOL. 13. ISSUE 7. P. 1002-1013 48 44% 29
10 KIM, SM , (2016) CELLULAR AND MOLECULAR MECHANISMS OF 3,3-DIINDOLYLMETHANE IN GASTROINTESTINAL CANCER.INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. VOL. 17. ISSUE 7. P. - 41 51% 0

Classes with closest relation at Level 1


Rank Class id link
1 11452 BISINDOLYLMETHANES//BISINDOLYL METHANES//INDOLE
2 892 SULFORAPHANE//GLUCOSINOLATES//ISOTHIOCYANATES
3 5815 CATECHOLESTROGENS//16 ALPHA HYDROXYESTRONE//ESTROGEN METABOLITES
4 27601 ASCORBIGEN//1 METHYLASCORBIGEN//METHYLASCORBIGEN
5 31935 DIETARY COMPOUNDS//MIR 1260B//3 UTR LUCIFERASE ASSAY
6 23738 M 3M3FBS//CHRON DIS HLTH PROMOT//FURA 2
7 355 ARYL HYDROCARBON RECEPTOR//TCDD//AHR
8 28538 2 7 BIINDOLYLS//FORMALDEHYDE EXTRUSION//IPSO SUBSTITUTION REACTIONS
9 27941 2 HYDROXY 2 2 BIINDAN 1 1 3 3 TETRONE//NINHYDRIN//AGR NAT OURCES BORAZJAN
10 33267 ATTA UR RAHMAN NAT PROD DISCOVERY//UCSS//COMPUTAT MED CHEM

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