Class information for:
Level 1: EZH2//POLYCOMB//BMI 1

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
1710 2524 52.3 94%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
71 3       GENETICS & HEREDITY//CHROMATIN//CELL BIOLOGY 83302
343 2             EZH2//CHROMATIN//POLYCOMB 17754
1710 1                   EZH2//POLYCOMB//BMI 1 2524

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 EZH2 authKW 2556085 13% 62% 340
2 POLYCOMB authKW 1472631 10% 51% 241
3 BMI 1 authKW 941457 5% 65% 120
4 BMI1 authKW 724981 4% 56% 107
5 POLYCOMB GROUP authKW 704220 3% 67% 87
6 POLYCOMB GROUP PROTEINS authKW 456253 3% 58% 65
7 POLYCOMB GROUP GENES authKW 337935 1% 76% 37
8 ENHANCER OF ZESTE HOMOLOG 2 authKW 328517 2% 70% 39
9 PRC2 authKW 281462 2% 48% 48
10 DZNEP authKW 240247 1% 83% 24

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Cell Biology 12975 37% 0% 936
2 Developmental Biology 8602 12% 0% 303
3 Oncology 6820 28% 0% 706
4 Genetics & Heredity 5067 20% 0% 493
5 Biochemistry & Molecular Biology 3390 33% 0% 826
6 Cell & Tissue Engineering 970 2% 0% 48
7 Hematology 545 5% 0% 133
8 Pathology 238 3% 0% 87
9 Medicine, Research & Experimental 176 4% 0% 109
10 Biophysics 91 3% 0% 84

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CANC EPIGENET DISCOVERY PERFORMANCE UNIT 81305 0% 61% 11
2 EQUIPE CHROMATINE DEV 38706 0% 80% 4
3 DEV EPIGENET GRP 29627 0% 35% 7
4 CHROMATIN BIOL TRANSCRIPT 24192 0% 100% 2
5 CHROMATIN CHROMOSOME BIOL 24192 0% 100% 2
6 DESARROLLO BIOL CELULAR 24192 0% 100% 2
7 EPIGENET CELLULAR SENESCENCE GRP 24192 0% 100% 2
8 TOUSEI KU 24192 0% 100% 2
9 DIFFERENTIAT CANC 24188 0% 50% 4
10 CANC BIOL DRUG DISCOVERY PHD PROGRAM 21771 0% 60% 3

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MOLECULAR CELL 6869 2% 1% 56
2 GENES & DEVELOPMENT 6360 2% 1% 63
3 DEVELOPMENT 5554 3% 1% 77
4 EPIGENOMICS 4400 1% 3% 13
5 ONCOTARGET 3696 2% 1% 62
6 MOLECULAR AND CELLULAR BIOLOGY 3447 3% 0% 81
7 CELL STEM CELL 3445 1% 2% 17
8 EPIGENETICS & CHROMATIN 2663 0% 3% 8
9 MECHANISMS OF DEVELOPMENT 2579 1% 1% 26
10 COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY SERIES 1742 1% 1% 27

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 EZH2 2556085 13% 62% 340 Search EZH2 Search EZH2
2 POLYCOMB 1472631 10% 51% 241 Search POLYCOMB Search POLYCOMB
3 BMI 1 941457 5% 65% 120 Search BMI+1 Search BMI+1
4 BMI1 724981 4% 56% 107 Search BMI1 Search BMI1
5 POLYCOMB GROUP 704220 3% 67% 87 Search POLYCOMB+GROUP Search POLYCOMB+GROUP
6 POLYCOMB GROUP PROTEINS 456253 3% 58% 65 Search POLYCOMB+GROUP+PROTEINS Search POLYCOMB+GROUP+PROTEINS
7 POLYCOMB GROUP GENES 337935 1% 76% 37 Search POLYCOMB+GROUP+GENES Search POLYCOMB+GROUP+GENES
8 ENHANCER OF ZESTE HOMOLOG 2 328517 2% 70% 39 Search ENHANCER+OF+ZESTE+HOMOLOG+2 Search ENHANCER+OF+ZESTE+HOMOLOG+2
9 PRC2 281462 2% 48% 48 Search PRC2 Search PRC2
10 DZNEP 240247 1% 83% 24 Search DZNEP Search DZNEP

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 WANG, W , QIN, JJ , VORUGANTI, S , NAG, S , ZHOU, JW , ZHANG, RW , (2015) POLYCOMB GROUP (PCG) PROTEINS AND HUMAN CANCERS: MULTIFACETED FUNCTIONS AND THERAPEUTIC IMPLICATIONS.MEDICINAL RESEARCH REVIEWS. VOL. 35. ISSUE 6. P. 1220 -1267 232 74% 3
2 KOPPENS, M , VAN LOHUIZEN, M , (2016) CONTEXT-DEPENDENT ACTIONS OF POLYCOMB REPRESSORS IN CANCER.ONCOGENE. VOL. 35. ISSUE 11. P. 1341 -1352 134 73% 12
3 SIMON, JA , KINGSTON, RE , (2013) OCCUPYING CHROMATIN: POLYCOMB MECHANISMS FOR GETTING TO GENOMIC TARGETS, STOPPING TRANSCRIPTIONAL TRAFFIC, AND STAYING PUT.MOLECULAR CELL. VOL. 49. ISSUE 5. P. 808 -824 113 74% 244
4 KIM, KH , ROBERTS, CWM , (2016) TARGETING EZH2 IN CANCER.NATURE MEDICINE. VOL. 22. ISSUE 2. P. 128 -134 82 70% 36
5 SIMON, JA , KINGSTON, RE , (2009) MECHANISMS OF POLYCOMB GENE SILENCING: KNOWNS AND UNKNOWNS.NATURE REVIEWS MOLECULAR CELL BIOLOGY. VOL. 10. ISSUE 10. P. 697 -708 110 66% 665
6 SCELFO, A , PIUNTI, A , PASINI, D , (2015) THE CONTROVERSIAL ROLE OF THE POLYCOMB GROUP PROTEINS IN TRANSCRIPTION AND CANCER: HOW MUCH DO WE NOT UNDERSTAND POLYCOMB PROTEINS?.FEBS JOURNAL. VOL. 282. ISSUE 9. P. 1703 -1722 147 78% 11
7 BAUER, M , TRUPKE, J , RINGROSE, L , (2016) THE QUEST FOR MAMMALIAN POLYCOMB RESPONSE ELEMENTS: ARE WE THERE YET?.CHROMOSOMA. VOL. 125. ISSUE 3. P. 471 -496 146 70% 4
8 SCHWARTZ, YB , PIRROTTA, V , (2013) A NEW WORLD OF POLYCOMBS: UNEXPECTED PARTNERSHIPS AND EMERGING FUNCTIONS.NATURE REVIEWS GENETICS. VOL. 14. ISSUE 12. P. 853 -864 111 78% 88
9 VOLKEL, P , DUPRET, B , LE BOURHIS, X , ANGRAND, PO , (2015) DIVERSE INVOLVEMENT OF EZH2 IN CANCER EPIGENETICS.AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH. VOL. 7. ISSUE 2. P. 175 -193 113 70% 35
10 PIUNTI, A , PASINI, D , (2011) EPIGENETIC FACTORS IN CANCER DEVELOPMENT: POLYCOMB GROUP PROTEINS.FUTURE ONCOLOGY. VOL. 7. ISSUE 1. P. 57 -75 141 77% 28

Classes with closest relation at Level 1


Rank Class id link
1 33345 MIR 101//MIR 26B//MICRORNA 101
2 12023 SET8//HISTONE//PR SET7
3 11594 CTCF//CONTROL GENET PROC//SUHW
4 14125 USP22//SET1//UBIQUITIN SPECIFIC PROTEASE 22
5 8082 HISTONE DEMETHYLASE//LSD1//HISTONE DEMETHYLATION
6 26432 YY1//YIN YANG 1//YY2
7 7575 HP1//POSITION EFFECT VARIEGATION//HETEROCHROMATIN
8 31526 ARID3B//JUMONJI//AT RICH INTERACTION DOMAIN
9 2738 ULTRABITHORAX//EXTRADENTICLE//HOMOTHORAX
10 5481 ARGININE METHYLATION//PROTEIN ARGININE METHYLTRANSFERASE//PRMT

Go to start page