Class information for:
Level 1: DSP 4//DSP 4 N 2 CHLOROETHYL N ETHYL 2 BROMOBENZYLAMINE//LOCUS COERULEUS

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
16972 624 47.6 61%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
8 4 CARDIAC & CARDIOVASCULAR SYSTEM//PERIPHERAL VASCULAR DISEASES//CARDIOL 1276458
57 3       ANGIOTENSIN II//HYPERTENSION//PERIPHERAL VASCULAR DISEASES 89232
1516 2             DEXMEDETOMIDINE//AGMATINE//IMIDAZOLINE RECEPTORS 7504
16972 1                   DSP 4//DSP 4 N 2 CHLOROETHYL N ETHYL 2 BROMOBENZYLAMINE//LOCUS COERULEUS 624

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 DSP 4 authKW 544895 6% 32% 35
2 DSP 4 N 2 CHLOROETHYL N ETHYL 2 BROMOBENZYLAMINE authKW 284700 1% 73% 8
3 LOCUS COERULEUS authKW 257152 14% 6% 85
4 XYLAMINE authKW 174760 1% 71% 5
5 DSP4 authKW 171847 2% 29% 12
6 NEUROBIOL 1 address 114169 1% 33% 7
7 N 2 CHLOROETHYL N ETHYL 2 BROMOBENZYLAMINE authKW 94097 1% 38% 5
8 DEXEFAROXAN authKW 88078 0% 60% 3
9 NORADRENALINE authKW 85615 13% 2% 83
10 NW NETWORK MENTAL ILLNESS EDUC CLIN address 81549 1% 33% 5

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Neurosciences 9317 70% 0% 435
2 Behavioral Sciences 2073 13% 0% 83
3 Pharmacology & Pharmacy 837 23% 0% 144
4 Geriatrics & Gerontology 304 4% 0% 25
5 Clinical Neurology 258 10% 0% 64
6 Psychology, Biological 185 2% 0% 13
7 Psychiatry 129 6% 0% 39
8 Psychology 86 3% 0% 19
9 Medicine, Research & Experimental 17 3% 0% 20
10 Biochemistry & Molecular Biology 15 9% 0% 57

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 NEUROBIOL 1 114169 1% 33% 7
2 NW NETWORK MENTAL ILLNESS EDUC CLIN 81549 1% 33% 5
3 9 QUAI ST BERNARD 48934 0% 100% 1
4 ANAL MOVIMENTO LAMB 48934 0% 100% 1
5 BIO AGROFOOD SCI 48934 0% 100% 1
6 BIOPSYCHOL BEHAV NEUROSCI DO OL PROGRAM 48934 0% 100% 1
7 BRAIN AGIGN DEMENTIA 48934 0% 100% 1
8 CNRS NEUROSCI NEUROPHYSIOL COMPAREE 48934 0% 100% 1
9 DEV PSYCHOBIOL PSYCHOL 48934 0% 100% 1
10 EXPT EPIDEMIOL 48934 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BEHAVIORAL AND NEURAL BIOLOGY 3873 2% 1% 10
2 NEUROBIOLOGY OF AGING 3046 3% 0% 19
3 BRAIN RESEARCH 2433 8% 0% 49
4 JOURNAL OF NEURAL TRANSMISSION 2332 2% 0% 14
5 BEHAVIOURAL BRAIN RESEARCH 2037 3% 0% 21
6 PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR 1879 4% 0% 22
7 JOURNAL OF COMPARATIVE AND PHYSIOLOGICAL PSYCHOLOGY 1550 0% 1% 3
8 NEUROTOXICITY RESEARCH 1240 1% 1% 5
9 NEURODEGENERATION 1175 0% 1% 2
10 PSYCHOPHARMACOLOGY 1146 3% 0% 17

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 DSP 4 544895 6% 32% 35 Search DSP+4 Search DSP+4
2 DSP 4 N 2 CHLOROETHYL N ETHYL 2 BROMOBENZYLAMINE 284700 1% 73% 8 Search DSP+4+N+2+CHLOROETHYL+N+ETHYL+2+BROMOBENZYLAMINE Search DSP+4+N+2+CHLOROETHYL+N+ETHYL+2+BROMOBENZYLAMINE
3 LOCUS COERULEUS 257152 14% 6% 85 Search LOCUS+COERULEUS Search LOCUS+COERULEUS
4 XYLAMINE 174760 1% 71% 5 Search XYLAMINE Search XYLAMINE
5 DSP4 171847 2% 29% 12 Search DSP4 Search DSP4
6 N 2 CHLOROETHYL N ETHYL 2 BROMOBENZYLAMINE 94097 1% 38% 5 Search N+2+CHLOROETHYL+N+ETHYL+2+BROMOBENZYLAMINE Search N+2+CHLOROETHYL+N+ETHYL+2+BROMOBENZYLAMINE
7 DEXEFAROXAN 88078 0% 60% 3 Search DEXEFAROXAN Search DEXEFAROXAN
8 NORADRENALINE 85615 13% 2% 83 Search NORADRENALINE Search NORADRENALINE
9 ABLATION STRATEGY 48934 0% 100% 1 Search ABLATION+STRATEGY Search ABLATION+STRATEGY
10 ADRA2B POLYMORPHISMS 48934 0% 100% 1 Search ADRA2B+POLYMORPHISMS Search ADRA2B+POLYMORPHISMS

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 ROSS, SB , STENFORS, C , (2015) DSP4, A SELECTIVE NEUROTOXIN FOR THE LOCUS COERULEUS NORADRENERGIC SYSTEM. A REVIEW OF ITS MODE OF ACTION.NEUROTOXICITY RESEARCH. VOL. 27. ISSUE 1. P. 15 -30 49 55% 3
2 FEINSTEIN, DL , KALININ, S , BRAUN, D , (2016) CAUSES, CONSEQUENCES, AND CURES FOR NEUROINFLAMMATION MEDIATED VIA THE LOCUS COERULEUS: NORADRENERGIC SIGNALING SYSTEM.JOURNAL OF NEUROCHEMISTRY. VOL. 139. ISSUE . P. 154 -178 74 29% 1
3 KOIV, K , ZOBEL, R , RAUDKIVI, K , KIVASTIK, T , HARRO, J , (2011) THE EFFECT OF DENERVATION OF THE LOCUS COERULEUS PROJECTIONS WITH N-(2-CHLOROETHYL)-N-ETHYL-2-BROMOBENZYLAMINE (DSP-4) ON COCAINE-INDUCED LOCOMOTION AND PLACE PREFERENCE IN RATS.BEHAVIOURAL BRAIN RESEARCH. VOL. 216. ISSUE 1. P. 172-179 36 47% 3
4 SZOT, P , MIGUELEZ, C , WHITE, SS , FRANKLIN, A , SIKKEMA, C , WILKINSON, CW , UGEDO, L , RASKIND, MA , (2010) A COMPREHENSIVE ANALYSIS OF THE EFFECT OF DSP4 ON THE LOCUS COERULEUS NORADRENERGIC SYSTEM IN THE RAT.NEUROSCIENCE. VOL. 166. ISSUE 1. P. 279-291 32 48% 25
5 JARDANHAZI-KURUTZ, D , KUMMER, MP , TERWEL, D , VOGEL, K , THIELE, A , HENEKA, MT , (2011) DISTINCT ADRENERGIC SYSTEM CHANGES AND NEUROINFLAMMATION IN RESPONSE TO INDUCED LOCUS CERULEUS DEGENERATION IN APP/PS1 TRANSGENIC MICE.NEUROSCIENCE. VOL. 176. ISSUE . P. 396 -407 29 48% 26
6 POLAK, PE , KALININ, S , FEINSTEIN, DL , (2011) LOCUS COERULEUS DAMAGE AND NORADRENALINE REDUCTIONS IN MULTIPLE SCLEROSIS AND EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS.BRAIN. VOL. 134. ISSUE . P. 665 -677 30 46% 19
7 HARRO, J , MERIKULA, A , LEPIKU, M , MODIRI, AR , RINKEN, A , ORELAND, L , (2000) LESIONING OF LOCUS COERULEUS PROJECTIONS BY DSP-4 NEUROTOXIN TREATMENT: EFFECT ON AMPHETAMINE-INDUCED HYPERLOCOMOTION AND DOPAMINE D-2 RECEPTOR BINDING IN RATS.PHARMACOLOGY & TOXICOLOGY. VOL. 86. ISSUE 5. P. 197-202 25 76% 27
8 SZOT, P , FRANKLIN, A , SIKKEMA, C , WILKINSON, CW , RASKIND, MA , (2012) SEQUENTIAL LOSS OF LC NORADRENERGIC AND DOPAMINERGIC NEURONS RESULTS IN A CORRELATION OF DOPAMINERGIC NEURONAL NUMBER TO STRIATAL DOPAMINE CONCENTRATION.FRONTIERS IN PHARMACOLOGY. VOL. 3. ISSUE . P. - 30 45% 7
9 GANNON, M , CHE, PL , CHEN, YJ , JIAO, K , ROBERSON, ED , WANG, Q , (2015) NORADRENERGIC DYSFUNCTION IN ALZHEIMER'S DISEASE.FRONTIERS IN NEUROSCIENCE. VOL. 9. ISSUE . P. - 41 28% 6
10 WANG, Y , MUSICH, PR , CUI, K , ZOU, Y , ZHU, MY , (2015) NEUROTOXIN-INDUCED DNA DAMAGE IS PERSISTENT IN SH-SY5Y CELLS AND LC NEURONS.NEUROTOXICITY RESEARCH. VOL. 27. ISSUE 4. P. 368 -383 27 45% 0

Classes with closest relation at Level 1


Rank Class id link
1 9827 GUANFACINE//LOCUS COERULEUS//NORADRENERGIC AXON
2 17880 LATENT INHIBITION//CONDITIONED OLFACTORY AVERSION//KAMIN BLOCKING
3 33927 TURN ALTERNATION//AVOIDANCE FEAR//BRAIN DAMAGE RECOVERY
4 24601 PUSH PULL SUPERFUSION//PUSH PULL CANNULA//RU24722
5 31461 5 HYDROXYINDOLE ACETIC ACID CLEARANCE//ACUTE SAMPLING//ALZHEIMERS GAMMA SECRETASE
6 27403 EVANS BLUE//1 DEOXY 1 NITRO D MANNITOL//ADENYLATE CYSLASE
7 11228 SOMATOSTATIN LIKE IMMUNOREACTIVITY//IRREGULAR ORIENTATION//MED BIOMED SCI NEUROSCI
8 21116 METHYLAZOXYMETHANOL//MICRENCEPHALY//METHYLAZOXYMETHANOL ACETATE
9 4499 POLISH JOURNAL OF PHARMACOLOGY AND PHARMACY//ISOPRENALINE INDUCED DRINKING//ELECTROCONVULSIVE SHOCK
10 9490 ALPHA2 ADRENOCEPTOR SUBTYPES//ALPHA2C ADRENOCEPTOR//ALPHA2A ADRENOCEPTOR

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