Class information for:
Level 1: PYROGEN TEST//PYROGEN//MONOCYTE ACTIVATION TEST

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
16708 640 30.2 59%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
449 3       FAMILIAL MEDITERRANEAN FEVER//TOLL LIKE RECEPTORS//INFLAMMASOME 25887
1872 2             LIPID A//ENDOTOXIN//LIPID A ANALOG 6024
16708 1                   PYROGEN TEST//PYROGEN//MONOCYTE ACTIVATION TEST 640

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PYROGEN TEST authKW 678542 3% 89% 16
2 PYROGEN authKW 585166 6% 31% 39
3 MONOCYTE ACTIVATION TEST authKW 572523 2% 100% 12
4 RABBIT PYROGEN TEST authKW 481076 2% 92% 11
5 LAL TEST authKW 213799 2% 41% 11
6 LIMULUS AMEBOCYTE LYSATE authKW 186210 2% 35% 11
7 AMEBOCYTE LYSATE authKW 143131 0% 100% 3
8 MONOCYTOID CELL LINES authKW 143131 0% 100% 3
9 HORSESHOE CRAB authKW 141173 3% 14% 21
10 LIMULUS TEST authKW 134238 2% 26% 11

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Microbiology 482 13% 0% 81
2 Biochemical Research Methods 422 9% 0% 60
3 Biochemistry & Molecular Biology 399 24% 0% 154
4 Immunology 372 13% 0% 84
5 Pharmacology & Pharmacy 315 15% 0% 97
6 Integrative & Complementary Medicine 243 3% 0% 16
7 Biotechnology & Applied Microbiology 230 9% 0% 60
8 Chemistry, Analytical 196 9% 0% 57
9 BIOLOGY, MISCELLANEOUS 120 0% 0% 2
10 Biophysics 108 6% 0% 37

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 LAL DEV GRP 95420 0% 100% 2
2 AEROB VET BACTERIAL VACCINE 47710 0% 100% 1
3 AESCUL 47710 0% 100% 1
4 AFSNIT 7641 INFECT DISENDOTOXIN 47710 0% 100% 1
5 BIOCHEM PHARMACOL STEINBEIS TECHNOL TRANSFER CT 47710 0% 100% 1
6 BIOPHARMACEUT PREPARAT 47710 0% 100% 1
7 BIOTECH OPERAT 47710 0% 100% 1
8 CEIT IK TECNUN 4 47710 0% 100% 1
9 CELL RECOGNIT PONSEAOBA KU 47710 0% 100% 1
10 COUNCILIDEHU PHARM BIOCHEM 47710 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ALTEX-ALTERNATIVEN ZU TIEREXPERIMENTEN 32501 2% 5% 15
2 JOURNAL OF PARENTERAL SCIENCE AND TECHNOLOGY 19632 1% 6% 7
3 JOURNAL OF ENDOTOXIN RESEARCH 10456 2% 2% 11
4 PDA JOURNAL OF PHARMACEUTICAL SCIENCE AND TECHNOLOGY 6397 1% 2% 6
5 BIOLOGICALS 3491 2% 1% 10
6 BIOLOGICAL BULLETIN 2524 2% 0% 13
7 ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION 2505 0% 2% 3
8 JOURNAL OF IMMUNOLOGICAL METHODS 2364 3% 0% 22
9 INNATE IMMUNITY 2324 1% 1% 5
10 JOURNAL OF IMMUNOASSAY 1823 1% 1% 4

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 PYROGEN TEST 678542 3% 89% 16 Search PYROGEN+TEST Search PYROGEN+TEST
2 PYROGEN 585166 6% 31% 39 Search PYROGEN Search PYROGEN
3 MONOCYTE ACTIVATION TEST 572523 2% 100% 12 Search MONOCYTE+ACTIVATION+TEST Search MONOCYTE+ACTIVATION+TEST
4 RABBIT PYROGEN TEST 481076 2% 92% 11 Search RABBIT+PYROGEN+TEST Search RABBIT+PYROGEN+TEST
5 LAL TEST 213799 2% 41% 11 Search LAL+TEST Search LAL+TEST
6 LIMULUS AMEBOCYTE LYSATE 186210 2% 35% 11 Search LIMULUS+AMEBOCYTE+LYSATE Search LIMULUS+AMEBOCYTE+LYSATE
7 AMEBOCYTE LYSATE 143131 0% 100% 3 Search AMEBOCYTE+LYSATE Search AMEBOCYTE+LYSATE
8 MONOCYTOID CELL LINES 143131 0% 100% 3 Search MONOCYTOID+CELL+LINES Search MONOCYTOID+CELL+LINES
9 HORSESHOE CRAB 141173 3% 14% 21 Search HORSESHOE+CRAB Search HORSESHOE+CRAB
10 LIMULUS TEST 134238 2% 26% 11 Search LIMULUS+TEST Search LIMULUS+TEST

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 KAWABATA, S , MUTA, T , (2010) SADAAKI IWANAGA: DISCOVERY OF THE LIPOPOLYSACCHARIDE- AND BETA-1,3-D-GLUCAN-MEDIATED PROTEOLYTIC CASCADE AND UNIQUE PROTEINS IN INVERTEBRATE IMMUNITY.JOURNAL OF BIOCHEMISTRY. VOL. 147. ISSUE 5. P. 611 -618 39 76% 6
2 IWANAGA, S , KAWABATA, S , MUTA, T , (1998) NEW TYPES OF CLOTTING FACTORS AND DEFENSE MOLECULES FOUND IN HORSESHOE CRAB HEMOLYMPH: THEIR STRUCTURES AND FUNCTIONS.JOURNAL OF BIOCHEMISTRY. VOL. 123. ISSUE 1. P. 1 -15 49 53% 177
3 OSAKI, T , KAWABATA, S , (2004) STRUCTURE AND FUNCTION OF COAGULOGEN, A CLOTTABLE PROTEIN IN HORSESHOE CRABS.CELLULAR AND MOLECULAR LIFE SCIENCES. VOL. 61. ISSUE 11. P. 1257-1265 50 48% 36
4 KAWABATA, S , (2010) IMMUNOCOMPETENT MOLECULES AND THEIR RESPONSE NETWORK IN HORSESHOE CRABS.INVERTEBRATE IMMUNITY. VOL. 708. ISSUE . P. 122 -136 39 52% 10
5 HARTUNG, T , (2015) THE HUMAN WHOLE BLOOD PYROGEN TEST - LESSONS LEARNED IN TWENTY YEARS.ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION. VOL. 32. ISSUE 2. P. 79 -100 43 38% 4
6 HARTUNG, T , HASIWA, N , DANESHIAN, M , HOLTKAMP, B , SCHMITZ, G , HOSSFELD, A , (2013) A TRUELY HUMAN(E) DETERMINATION OF ENDOTOXINS AND NON-ENDOTOXIN PYROGENS.PHARMAZEUTISCHE INDUSTRIE. VOL. 75. ISSUE 5. P. 825-834 46 40% 0
7 IWANAGA, S , MIYATA, T , TOKUNAGA, F , MUTA, T , (1992) MOLECULAR MECHANISM OF HEMOLYMPH CLOTTING SYSTEM IN LIMULUS.THROMBOSIS RESEARCH. VOL. 68. ISSUE 1. P. 1-32 43 72% 69
8 SU, WQ , DING, XT , (2015) METHODS OF ENDOTOXIN DETECTION.JALA. VOL. 20. ISSUE 4. P. 354 -364 36 39% 4
9 SUN, HX , MIAO, P , TANG, YG , WANG, BD , QIAN, J , WANG, DY , (2015) AN ELASTOGRAPHY ANALYTICAL METHOD FOR THE RAPID DETECTION OF ENDOTOXIN.ANALYST. VOL. 140. ISSUE 13. P. 4374 -4378 19 76% 1
10 DA SILVA, CC , PRESGRAVE, OAF , HARTUNG, T , DE MORAES, AML , DELGADO, IF , (2016) APPLICABILITY OF THE MONOCYTE ACTIVATION TEST (MAT) FOR HYPERIMMUNE SERA IN THE ROUTINE OF THE QUALITY CONTROL LABORATORY: COMPARISON WITH THE RABBIT PYROGEN TEST (RPT).TOXICOLOGY IN VITRO. VOL. 32. ISSUE . P. 70 -75 16 89% 0

Classes with closest relation at Level 1


Rank Class id link
1 25445 ENDOTOXIN REMOVAL//HUMAN LIKE COLLAGEN//SHAANXI DE ABLE BIOMED MAT
2 36835 TOXICITY ASSESSMENT OF TREATED WASTEWATER//2 KETO 3 DEOXYOCTULOSONIC ACID KDO//ACTIVATED SLUDGE DECAY PROCESS
3 20506 LEIBNIZ ZENTRUM MED BIOWISSEN//LALF//LIPID A
4 10017 ANTILIPID A//ANTIBIOTIC INDUCED ENDOTOXIN RELEASE//ANTILIPOPOLYSACCHARIDE
5 25102 POLYMYXIN B IMMOBILIZED FIBER//PMX DHP//ENDOTOXIN ACTIVITY ASSAY
6 8690 PROPHENOLOXIDASE//CLIP DOMAIN//PHENOLOXIDASE
7 21738 HORSESHOE CRAB//LIMULUS POLYPHEMUS//TACHYPLEUS TRIDENTATUS
8 12343 C TYPE LECTIN//RHAMNOSE BINDING LECTIN//CUCUMARIA ECHINATA
9 37139 CISPLATIN PHOSPHONIC ACIDS//COLONY STIMULATING FACTOR CSF//COLONY FORMING UNIT CFU
10 34818 ANDROGEN DISRUPTING CHEMICALS//CARDIOMYOPATHY DILATED MYOCARDITIS//CLOSTRIDIAL GENETICS

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