Class information for:
Level 1: APELIN//APJ//APELIN 13

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
14760 752 41.9 92%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
66 3       LEPTIN//ADIPONECTIN//ENDOCRINOLOGY & METABOLISM 84415
320 2             LEPTIN//ADIPONECTIN//RESISTIN 18237
14760 1                   APELIN//APJ//APELIN 13 752

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 APELIN authKW 12035408 48% 81% 364
2 APJ authKW 4228625 14% 96% 108
3 APELIN 13 authKW 1597377 6% 91% 43
4 APJ RECEPTOR authKW 1138268 4% 97% 29
5 APELIN RECEPTOR authKW 906337 3% 89% 25
6 LEARNING PHARMACOPROTE address 442128 2% 78% 14
7 APELIN 12 authKW 328892 1% 90% 9
8 APELIN APJ authKW 208820 1% 86% 6
9 U691 address 137028 1% 38% 9
10 AGTRL1 authKW 121812 0% 100% 3

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Endocrinology & Metabolism 2228 22% 0% 163
2 Peripheral Vascular Diseases 720 10% 0% 73
3 Cardiac & Cardiovascular System 592 12% 0% 91
4 Physiology 467 9% 0% 71
5 Biochemistry & Molecular Biology 350 22% 0% 162
6 Medicine, Research & Experimental 267 8% 0% 61
7 Cell Biology 200 10% 0% 77
8 Pharmacology & Pharmacy 178 11% 0% 86
9 Developmental Biology 97 3% 0% 20
10 Biophysics 77 5% 0% 36

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 LEARNING PHARMACOPROTE 442128 2% 78% 14
2 U691 137028 1% 38% 9
3 CENT NEUROPEPTIDES REGULAT WATER BALANCE 81208 0% 100% 2
4 UNITE ENVIRONM PERINATAL CROISSANCEEA 4489 81208 0% 100% 2
5 UNITE INSERM U397 81208 0% 100% 2
6 UNITE U589 81208 0% 100% 2
7 CENT NEUROPEPTIDES REGULAT BODY FLUID HOMEOST 64962 1% 40% 4
8 UNITE ENVIRONM PERINATAL SANTE 54138 0% 67% 2
9 HUNAN PROV COOPERAT INNOVAT MOL TARGET NEW DR 49729 1% 18% 7
10 US006 45676 0% 38% 3

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 REGULATORY PEPTIDES 4522 3% 0% 23
2 PEPTIDES 4421 4% 0% 31
3 ACTA BIOCHIMICA ET BIOPHYSICA SINICA 1190 1% 0% 9
4 BIOMARKERS IN MEDICINE 932 1% 1% 4
5 INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS 671 0% 1% 3
6 JOURNAL OF NEUROENDOCRINOLOGY 615 1% 0% 7
7 JOURNAL OF CARDIAC FAILURE 584 1% 0% 5
8 MINERVA ENDOCRINOLOGICA 566 0% 1% 2
9 HYPERTENSION IN PREGNANCY 435 0% 0% 3
10 OBESITY AND METABOLISM-MILAN 421 0% 1% 1

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 APELIN 12035408 48% 81% 364 Search APELIN Search APELIN
2 APJ 4228625 14% 96% 108 Search APJ Search APJ
3 APELIN 13 1597377 6% 91% 43 Search APELIN+13 Search APELIN+13
4 APJ RECEPTOR 1138268 4% 97% 29 Search APJ+RECEPTOR Search APJ+RECEPTOR
5 APELIN RECEPTOR 906337 3% 89% 25 Search APELIN+RECEPTOR Search APELIN+RECEPTOR
6 APELIN 12 328892 1% 90% 9 Search APELIN+12 Search APELIN+12
7 APELIN APJ 208820 1% 86% 6 Search APELIN+APJ Search APELIN+APJ
8 AGTRL1 121812 0% 100% 3 Search AGTRL1 Search AGTRL1
9 APELIN APJ SYSTEM 121812 0% 100% 3 Search APELIN+APJ+SYSTEM Search APELIN+APJ+SYSTEM
10 APELIN PROTEIN 121812 0% 100% 3 Search APELIN+PROTEIN Search APELIN+PROTEIN

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 O'CARROLL, AM , LOLAIT, SJ , HARRIS, LE , POPE, GR , (2013) THE APELIN RECEPTOR APJ: JOURNEY FROM AN ORPHAN TO A MULTIFACETED REGULATOR OF HOMEOSTASIS.JOURNAL OF ENDOCRINOLOGY. VOL. 219. ISSUE 1. P. R13-R35 156 85% 58
2 PITKIN, SL , MAGUIRE, JJ , BONNER, TI , DAVENPORT, AP , (2010) INTERNATIONAL UNION OF BASIC AND CLINICAL PHARMACOLOGY. LXXIV. APELIN RECEPTOR NOMENCLATURE, DISTRIBUTION, PHARMACOLOGY, AND FUNCTION.PHARMACOLOGICAL REVIEWS. VOL. 62. ISSUE 3. P. 331-342 133 94% 50
3 CHAVES-ALMAGRO, C , CASTAN-LAURELL, I , DRAY, C , KNAUF, C , VALET, P , MASRI, B , (2015) APELIN RECEPTORS: FROM SIGNALING TO ANTIDIABETIC STRATEGY.EUROPEAN JOURNAL OF PHARMACOLOGY. VOL. 763. ISSUE . P. 149 -159 111 90% 5
4 YU, XH , TANG, ZB , LIU, LJ , QIAN, H , TANG, SL , ZHANG, DW , TIAN, GP , TANG, CK , (2014) APELIN AND ITS RECEPTOR APJ IN CARDIOVASCULAR DISEASES.CLINICA CHIMICA ACTA. VOL. 428. ISSUE . P. 1-8 84 92% 14
5 YANG, PR , MAGUIRE, JJ , DAVENPORT, AP , (2015) APELIN, ELABELA/TODDLER, AND BIASED AGONISTS AS NOVEL THERAPEUTIC AGENTS IN THE CARDIOVASCULAR SYSTEM.TRENDS IN PHARMACOLOGICAL SCIENCES. VOL. 36. ISSUE 9. P. 560 -567 90 88% 3
6 CARPENE, C , DRAY, C , ATTANE, C , VALET, P , PORTILLO, MP , CHURRUCA, I , MILAGRO, FI , CASTAN-LAURE, I , (2007) EXPANDING ROLE FOR THE APELIN/APJ SYSTEM IN PHYSIOPATHOLOGY.JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY. VOL. 63. ISSUE 4. P. 359 -373 89 95% 62
7 FALCAO-PIRES, I , LADEIRAS-LOPES, R , LEITE-MOREIRA, AF , (2010) THE APELINERGIC SYSTEM: A PROMISING THERAPEUTIC TARGET.EXPERT OPINION ON THERAPEUTIC TARGETS. VOL. 14. ISSUE 6. P. 633-645 83 87% 19
8 NARAYANAN, S , HARRIS, DL , MAITRA, R , RUNYON, SP , (2015) REGULATION OF THE APELINERGIC SYSTEM AND ITS POTENTIAL IN CARDIOVASCULAR DISEASE: PEPTIDES AND SMALL MOLECULES AS TOOLS FOR DISCOVERY.JOURNAL OF MEDICINAL CHEMISTRY. VOL. 58. ISSUE 20. P. 7913 -7927 64 94% 5
9 CHARLES, CJ , (2011) UPDATE ON APELIN PEPTIDES AS PUTATIVE TARGETS FOR CARDIOVASCULAR DRUG DISCOVERY.EXPERT OPINION ON DRUG DISCOVERY. VOL. 6. ISSUE 6. P. 633 -644 77 92% 3
10 DALZELL, JR , ROCCHICCIOLI, JP , WEIR, RAP , JACKSON, CE , PADMANABHAN, N , GARDNER, RS , PETRIE, MC , MCMURRAY, JJV , (2015) THE EMERGING POTENTIAL OF THE APELIN-APJ SYSTEM IN HEART FAILURE.JOURNAL OF CARDIAC FAILURE. VOL. 21. ISSUE 6. P. 489 -498 75 80% 4

Classes with closest relation at Level 1


Rank Class id link
1 16106 CHEMERIN//VASPIN//OMENTIN
2 11974 VISFATIN//NAMPT//NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE
3 36613 PROLYLCARBOXYPEPTIDASE//PRCP//ANGIOTENSINASE C
4 6313 ANGIOTENSIN 1 7//ANGIOTENSIN CONVERTING ENZYME 2//MAS RECEPTOR
5 22727 NESFATIN 1//NUCB2//NUCLEOBINDIN 2
6 29958 SALUSIN//SALUSIN ALPHA//SALUSIN BETA
7 11468 RESISTIN//RESISTIN LIKE MOLECULE BETA//RELM ALPHA
8 10443 LEPTIN//SPECIALIZED HYPERTENS GENET//HYPERTENS GENET SPECIALIZED
9 28909 GPRC5A//GPR12//GPR139
10 9142 RECEPTOR MOSAICS//HETEROMER//RECEPTOR RECEPTOR INTERACTIONS

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