Class information for:
Level 1: CADASIL//NOTCH3//NOTCH3 GENE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
14523 765 33.1 86%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
27 3       DEVELOPMENTAL BIOLOGY//DEVELOPMENT//AGR2 109777
2542 2             CADASIL//NOTCH3//NOTCH 3755
14523 1                   CADASIL//NOTCH3//NOTCH3 GENE 765

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CADASIL authKW 13257286 51% 85% 393
2 NOTCH3 authKW 2665089 16% 53% 125
3 NOTCH3 GENE authKW 1398071 5% 97% 36
4 CARASIL authKW 521543 2% 93% 14
5 CEREBRAL AUTOSOMAL DOMINANT ARTERIOPATHY WITH SUBCORTICAL INFARCTS AND LEUKOENCEPHALOPATHY authKW 460181 2% 82% 14
6 U740 address 443472 3% 56% 20
7 GOM authKW 421588 2% 81% 13
8 CEREBRAL AUTOSOMAL DOMINANT ARTERIOPATHY WITH SUBCORTICAL INFARCTS AND LEUKOENCEPHALOPATHY CADASIL authKW 319313 1% 100% 8
9 NOTCH3 MUTATIONS authKW 283832 1% 89% 8
10 GRANULAR OSMIOPHILIC MATERIAL authKW 244472 1% 88% 7

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Clinical Neurology 16334 63% 0% 481
2 Neurosciences 2744 36% 0% 273
3 Peripheral Vascular Diseases 1706 14% 0% 110
4 Pathology 942 10% 0% 80
5 Neuroimaging 373 3% 0% 22
6 Psychiatry 159 6% 0% 48
7 Geriatrics & Gerontology 88 2% 0% 16
8 Genetics & Heredity 63 5% 0% 40
9 Medicine, General & Internal 46 5% 0% 41
10 Radiology, Nuclear Medicine & Medical Imaging 16 3% 0% 24

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 U740 443472 3% 56% 20
2 UMRS 1161 239485 1% 100% 6
3 GENET PATHOGENESIS CEREBROVASC DIS 159656 1% 100% 4
4 STROKE DEMENTIA 112591 4% 10% 29
5 U1161 89799 1% 38% 6
6 DOCTORAL COURSE ENVIRONM SCI PUBL HLTH 79828 0% 100% 2
7 EA 2691 MENRT 79828 0% 100% 2
8 REFERENCE MALAD RA VAISSEAUX CERVEAU CEI 79828 0% 100% 2
9 REFERENCE MALAD VASC RA CERVEAU OEIL CER 71843 0% 60% 3
10 UMR740 71843 0% 60% 3

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 STROKE 11057 8% 0% 63
2 NEUROLOGY 5246 7% 0% 53
3 FOLIA NEUROPATHOLOGICA 4709 1% 1% 10
4 JOURNAL OF STROKE & CEREBROVASCULAR DISEASES 3333 2% 1% 14
5 JOURNAL OF THE NEUROLOGICAL SCIENCES 3292 4% 0% 29
6 CEREBROVASCULAR DISEASES 2987 2% 1% 15
7 JOURNAL OF HEADACHE AND PAIN 2516 1% 1% 7
8 ACTA NEUROPATHOLOGICA 2195 2% 0% 18
9 NEUROLOGICAL SCIENCES 2072 2% 0% 13
10 JOURNAL OF NEUROLOGY 1875 2% 0% 17

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 CADASIL 13257286 51% 85% 393 Search CADASIL Search CADASIL
2 NOTCH3 2665089 16% 53% 125 Search NOTCH3 Search NOTCH3
3 NOTCH3 GENE 1398071 5% 97% 36 Search NOTCH3+GENE Search NOTCH3+GENE
4 CARASIL 521543 2% 93% 14 Search CARASIL Search CARASIL
5 CEREBRAL AUTOSOMAL DOMINANT ARTERIOPATHY WITH SUBCORTICAL INFARCTS AND LEUKOENCEPHALOPATHY 460181 2% 82% 14 Search CEREBRAL+AUTOSOMAL+DOMINANT+ARTERIOPATHY+WITH+SUBCORTICAL+INFARCTS+AND+LEUKOENCEPHALOPATHY Search CEREBRAL+AUTOSOMAL+DOMINANT+ARTERIOPATHY+WITH+SUBCORTICAL+INFARCTS+AND+LEUKOENCEPHALOPATHY
6 GOM 421588 2% 81% 13 Search GOM Search GOM
7 CEREBRAL AUTOSOMAL DOMINANT ARTERIOPATHY WITH SUBCORTICAL INFARCTS AND LEUKOENCEPHALOPATHY CADASIL 319313 1% 100% 8 Search CEREBRAL+AUTOSOMAL+DOMINANT+ARTERIOPATHY+WITH+SUBCORTICAL+INFARCTS+AND+LEUKOENCEPHALOPATHY+CADASIL Search CEREBRAL+AUTOSOMAL+DOMINANT+ARTERIOPATHY+WITH+SUBCORTICAL+INFARCTS+AND+LEUKOENCEPHALOPATHY+CADASIL
8 NOTCH3 MUTATIONS 283832 1% 89% 8 Search NOTCH3+MUTATIONS Search NOTCH3+MUTATIONS
9 GRANULAR OSMIOPHILIC MATERIAL 244472 1% 88% 7 Search GRANULAR+OSMIOPHILIC+MATERIAL Search GRANULAR+OSMIOPHILIC+MATERIAL
10 CEREBRAL AUTOSOMAL RECESSIVE ARTERIOPATHY WITH SUBCORTICAL INFARCTS AND LEUKOENCEPHALOPATHY 199571 1% 100% 5 Search CEREBRAL+AUTOSOMAL+RECESSIVE+ARTERIOPATHY+WITH+SUBCORTICAL+INFARCTS+AND+LEUKOENCEPHALOPATHY Search CEREBRAL+AUTOSOMAL+RECESSIVE+ARTERIOPATHY+WITH+SUBCORTICAL+INFARCTS+AND+LEUKOENCEPHALOPATHY

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 CHABRIAT, H , JOUTEL, A , DICHGANS, M , TOURNIER-LASSERVE, E , BOUSSER, MG , (2009) CADASIL.LANCET NEUROLOGY. VOL. 8. ISSUE 7. P. 643-653 102 89% 237
2 ANDRE, C , (2010) CADASIL PATHOGENESIS, CLINICAL AND RADIOLOGICAL FINDINGS AND TREATMENT.ARQUIVOS DE NEURO-PSIQUIATRIA. VOL. 68. ISSUE 2. P. 287-299 111 90% 18
3 TIKKA, S , BAUMANN, M , SIITONEN, M , PASANEN, P , POYHONEN, M , MYLLYKANGAS, L , VIITANEN, M , FUKUTAKE, T , COGNAT, E , JOUTEL, A , ET AL (2014) CADASIL AND CARASIL.BRAIN PATHOLOGY. VOL. 24. ISSUE 5. P. 525 -544 94 83% 13
4 RUTTEN, JW , HAAN, J , TERWINDT, GM , VAN DUINEN, SG , BOON, EMJ , OBERSTEIN, SAJL , (2014) INTERPRETATION OF NOTCH3 MUTATIONS IN THE DIAGNOSIS OF CADASIL.EXPERT REVIEW OF MOLECULAR DIAGNOSTICS. VOL. 14. ISSUE 5. P. 593-603 77 95% 11
5 HERVE, D , CHABRIAT, H , (2010) CADASIL.JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY. VOL. 23. ISSUE 4. P. 269-276 81 92% 28
6 GUNDA, B , CHABRIAT, H , BERECZKI, D , (2011) CADASIL AND OTHER HEREDITARY SMALL VESSEL DISEASES OF THE BRAIN - INCREASINGLY DIAGNOSED CONDITIONS UNDERLYING FAMILIAL ISCHAEMIC STROKE AND DEMENTIA.IDEGGYOGYASZATI SZEMLE-CLINICAL NEUROSCIENCE. VOL. 64. ISSUE 3-4. P. 88 -100 83 84% 2
7 DEL RIO-ESPINOLA, A , MENDIOROZ, M , DOMINGUES-MONTANARI, S , POZO-ROSICH, P , SOLE, E , FERNANDEZ-MORALES, J , FERNANDEZ-CADENAS, I , MONTANER, J , (2009) CADASIL MANAGEMENT OR I REVIEWS WHAT TO DO WHEN THERE IS LITTLE ONE CAN DO.EXPERT REVIEW OF NEUROTHERAPEUTICS. VOL. 9. ISSUE 2. P. 197-210 89 79% 8
8 YAMAMOTO, Y , CRAGGS, L , BAUMANN, M , KALIMO, H , KALARIA, RN , (2011) MOLECULAR GENETICS AND PATHOLOGY OF HEREDITARY SMALL VESSEL DISEASES OF THE BRAIN.NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY. VOL. 37. ISSUE 1. P. 94-113 94 62% 35
9 CHOI, JC , (2010) CEREBRAL AUTOSOMAL DOMINANT ARTERIOPATHY WITH SUBCORTICAL INFARCTS AND LEUKOENCEPHALOPATHY: A GENETIC CAUSE OF CEREBRAL SMALL VESSEL DISEASE.JOURNAL OF CLINICAL NEUROLOGY. VOL. 6. ISSUE 1. P. 1-9 64 97% 15
10 OBERSTEIN, SAJL , HAAN, J , (2004) CEREBRAL AUTOSOMAL DOMINANT ARTERIOPATHY WITH SUBCORTICAL INFARCTS AND LEUKOENCEPHALOPATHY (CADASIL).PANMINERVA MEDICA. VOL. 46. ISSUE 4. P. 265-276 70 92% 7

Classes with closest relation at Level 1


Rank Class id link
1 933 LEUKOARAIOSIS//WHITE MATTER HYPERINTENSITIES//WHITE MATTER LESIONS
2 15606 PRKCH//CHROMOSOME 12P13//PDE4D
3 29174 VIRCHOW ROBIN SPACES//PERIVASCULAR SPACE//DILATED VIRCHOW ROBIN SPACES
4 11708 DLL4//VASC PATTERNING//DELTA LIKE LIGAND 4
5 4073 CEREBRAL AMYLOID ANGIOPATHY//CEREBRAL MICROBLEEDS//MICROBLEEDS
6 8676 FAMILIAL HEMIPLEGIC MIGRAINE//HEMIPLEGIC MIGRAINE//CACNA1A
7 11425 MIGRAINE//CEPHALALGIA//MIGRAINE WITH AURA
8 29320 SUSAC SYNDROME//BRANCH RETINAL ARTERY OCCLUSION//ENDOTHELIOPATHY
9 12781 ALEXANDER DISEASE//LEUKODYSTROPHY//ROSENTHAL FIBERS
10 3238 NOTCH//NEUROGENIC GENES//SUPPRESSOR OF HAIRLESS

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