Class information for:
Level 1: ED B//ONCOFETAL FIBRONECTIN//PHILOCHEM AG

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
14450 769 43.9 86%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
307 3       INTEGRIN//ALPORT SYNDROME//LAMININ 40384
683 2             INTEGRIN//FOCAL ADHESION KINASE//TENASCIN C 13145
14450 1                   ED B//ONCOFETAL FIBRONECTIN//PHILOCHEM AG 769

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 ED B authKW 516184 2% 100% 13
2 ONCOFETAL FIBRONECTIN authKW 515000 3% 62% 21
3 PHILOCHEM AG address 424994 2% 63% 17
4 IMMUNOCYTOKINE authKW 323120 3% 35% 23
5 FIBRONECTIN ISOFORMS authKW 282609 1% 65% 11
6 EDB DOMAIN OF FIBRONECTIN authKW 277945 1% 100% 7
7 EXTRA DOMAIN A CONTAINING FIBRONECTIN authKW 277945 1% 100% 7
8 FIBRONECTIN authKW 272850 22% 4% 172
9 ARMED ANTIBODY authKW 243200 1% 88% 7
10 F8 ANTIBODY authKW 238239 1% 100% 6

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Cell Biology 1054 20% 0% 156
2 Oncology 958 20% 0% 152
3 Biochemistry & Molecular Biology 686 28% 0% 213
4 Rheumatology 204 3% 0% 25
5 Pathology 176 5% 0% 38
6 Biophysics 119 6% 0% 43
7 Peripheral Vascular Diseases 104 4% 0% 32
8 Hematology 85 4% 0% 31
9 Biochemical Research Methods 83 4% 0% 34
10 Developmental Biology 74 2% 0% 18

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PHILOCHEM AG 424994 2% 63% 17
2 UNIT INNOVAT THER IES 238239 1% 100% 6
3 CHEM PL BIOSCI 155416 14% 4% 108
4 RECOMBINANT THER EUT PROT 127059 1% 80% 4
5 ANTI ANGIOGENESIS 39706 0% 100% 1
6 ATOPY ALLER 39706 0% 100% 1
7 BIOCHEM CARDIAC MUSCLE 39706 0% 100% 1
8 BIOCHEM CELL MATRIX BIOL 39706 0% 100% 1
9 BIOMED SCI BIOTECHNOL BIOL GENET 39706 0% 100% 1
10 BIOMED SCI BIOTECHNOL HISTOL 39706 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CELL ADHESION AND COMMUNICATION 2319 1% 1% 4
2 MATRIX BIOLOGY 1436 1% 1% 7
3 CANCER IMMUNOLOGY RESEARCH 1407 1% 1% 4
4 PROTEIN ENGINEERING DESIGN & SELECTION 1365 1% 1% 6
5 INTERNATIONAL JOURNAL OF CANCER 920 3% 0% 22
6 EXPERIMENTAL CELL RESEARCH 774 2% 0% 16
7 HISTOCHEMISTRY AND CELL BIOLOGY 731 1% 0% 7
8 QUARTERLY JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING 656 0% 1% 3
9 JOURNAL OF PATHOLOGY 561 1% 0% 9
10 JOURNAL OF CELL BIOLOGY 536 2% 0% 15

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 ED B 516184 2% 100% 13 Search ED+B Search ED+B
2 ONCOFETAL FIBRONECTIN 515000 3% 62% 21 Search ONCOFETAL+FIBRONECTIN Search ONCOFETAL+FIBRONECTIN
3 IMMUNOCYTOKINE 323120 3% 35% 23 Search IMMUNOCYTOKINE Search IMMUNOCYTOKINE
4 FIBRONECTIN ISOFORMS 282609 1% 65% 11 Search FIBRONECTIN+ISOFORMS Search FIBRONECTIN+ISOFORMS
5 EDB DOMAIN OF FIBRONECTIN 277945 1% 100% 7 Search EDB+DOMAIN+OF+FIBRONECTIN Search EDB+DOMAIN+OF+FIBRONECTIN
6 EXTRA DOMAIN A CONTAINING FIBRONECTIN 277945 1% 100% 7 Search EXTRA+DOMAIN+A+CONTAINING+FIBRONECTIN Search EXTRA+DOMAIN+A+CONTAINING+FIBRONECTIN
7 FIBRONECTIN 272850 22% 4% 172 Search FIBRONECTIN Search FIBRONECTIN
8 ARMED ANTIBODY 243200 1% 88% 7 Search ARMED+ANTIBODY Search ARMED+ANTIBODY
9 F8 ANTIBODY 238239 1% 100% 6 Search F8+ANTIBODY Search F8+ANTIBODY
10 APTIDES 216177 1% 78% 7 Search APTIDES Search APTIDES

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 KUMRA, H , REINHARDT, DP , (2016) FIBRONECTIN-TARGETED DRUG DELIVERY IN CANCER.ADVANCED DRUG DELIVERY REVIEWS. VOL. 97. ISSUE . P. 101 -110 85 64% 0
2 WHITE, ES , BARALLE, FE , MURO, AF , (2008) NEW INSIGHTS INTO FORM AND FUNCTION OF FIBRONECTIN SPLICE VARIANTS.JOURNAL OF PATHOLOGY. VOL. 216. ISSUE 1. P. 1-14 60 47% 133
3 NERI, D , SONDEL, PM , (2016) IMMUNOCYTOKINES FOR CANCER TREATMENT: PAST, PRESENT AND FUTURE.CURRENT OPINION IN IMMUNOLOGY. VOL. 40. ISSUE . P. 96 -102 36 62% 4
4 ELIA, G , FUGMANN, T , NERI, D , (2014) FROM TARGET DISCOVERY TO CLINICAL TRIALS WITH ARMED ANTIBODY PRODUCTS.JOURNAL OF PROTEOMICS. VOL. 107. ISSUE . P. 50 -55 36 77% 2
5 KASPAR, M , ZARDI, L , NERI, D , (2006) FIBRONECTIN AS TARGET FOR TUMOR THERAPY.INTERNATIONAL JOURNAL OF CANCER. VOL. 118. ISSUE 6. P. 1331-1339 47 58% 109
6 KIEFER, JD , NERI, D , (2016) IMMUNOCYTOKINES AND BISPECIFIC ANTIBODIES: TWO COMPLEMENTARY STRATEGIES FOR THE SELECTIVE ACTIVATION OF IMMUNE CELLS AT THE TUMOR SITE.IMMUNOLOGICAL REVIEWS. VOL. 270. ISSUE 1. P. 178 -192 50 36% 6
7 PRETTO, F , ELIA, G , CASTIONI, N , NERI, D , (2014) PRECLINICAL EVALUATION OF IL2-BASED IMMUNOCYTOKINES SUPPORTS THEIR USE IN COMBINATION WITH DACARBAZINE, PACLITAXEL AND TNF-BASED IMMUNOTHERAPY.CANCER IMMUNOLOGY IMMUNOTHERAPY. VOL. 63. ISSUE 9. P. 901 -910 33 69% 6
8 HEMMERLE, T , NERI, D , (2014) THE ANTIBODY-BASED TARGETED DELIVERY OF INTERLEUKIN-4 AND 12 TO THE TUMOR NEOVASCULATURE ERADICATES TUMORS IN THREE MOUSE MODELS OF CANCER.INTERNATIONAL JOURNAL OF CANCER. VOL. 134. ISSUE 2. P. 467 -477 31 65% 12
9 MENRAD, A , MENSSEN, HD , (2005) ED-B FIBRONECTIN AS A TARGET FOR ANTIBODY-BASED CANCER TREATMENTS.EXPERT OPINION ON THERAPEUTIC TARGETS. VOL. 9. ISSUE 3. P. 491-500 35 70% 60
10 HEMMERLE, T , NERI, D , (2014) THE DOSE-DEPENDENT TUMOR TARGETING OF ANTIBODY-IFN GAMMA FUSION PROTEINS REVEALS AN UNEXPECTED RECEPTOR-TRAPPING MECHANISM IN VIVO.CANCER IMMUNOLOGY RESEARCH. VOL. 2. ISSUE 6. P. 559 -567 27 75% 2

Classes with closest relation at Level 1


Rank Class id link
1 11609 FIBRONECTIN//FIBRONECTIN DOMAINS//FN PROTEINASE
2 28998 FIBRONECTIN FRAGMENTS//BUDO SPORTS STUDIES//RED CROSS BLOOD SERV BADEN WURTTEMBERG HESSEN GGM
3 4438 PLASMA FIBRONECTIN//FIBRONECTIN//AGR ANIM MORPHOL
4 36285 RECOMBINANT FIBRONECTIN FRAGMENT//CBD HEPII POLYPEPTIDE//ND2001
5 35790 FACS MQ//ABCG2 BCRP GENE//ADULT RESIDENT THYROID STEM PROGENITOR CELLS
6 7904 TENASCIN C//TENASCIN//TENASCIN X
7 35653 MD ANDERSON CANC MED//BIOSSCI TECHNOL//DIFFERENTIATION INDUCING EFFECT
8 11281 ANTIBODY DRUG CONJUGATE//GEMTUZUMAB OZOGAMICIN//MYLOTARG
9 2335 INTEGRIN//INTEGRIN ALPHA 6 BETA 4//VLA 1
10 13046 PHAGE DISPLAY//IN VIVO PHAGE DISPLAY//NGR HTNF

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