Class information for:
Level 1: GUANYLIN//UROGUANYLIN//GUANYLYL CYCLASE C

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
13902 806 38.5 74%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
7 4 INFECTIOUS DISEASES//MICROBIOLOGY//VIROLOGY 1353914
368 3       THROMBOTIC THROMBOCYTOPENIC PURPURA//HEMOLYTIC UREMIC SYNDROME//SHIGA TOXIN 33921
403 2             STEC//ESCHERICHIA COLI//SHIGA TOXIN 16672
13902 1                   GUANYLIN//UROGUANYLIN//GUANYLYL CYCLASE C 806

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 GUANYLIN authKW 2606702 11% 79% 87
2 UROGUANYLIN authKW 2495668 10% 86% 77
3 GUANYLYL CYCLASE C authKW 1612330 7% 80% 53
4 HEAT STABLE ENTEROTOXIN authKW 1515306 7% 67% 60
5 GUANYLATE CYCLASE C authKW 690696 3% 65% 28
6 E COLI HEAT STABLE ENTEROTOXIN authKW 227302 1% 100% 6
7 GUCY2C authKW 220410 1% 73% 8
8 ESCHERICHIA COLI HEAT STABLE ENTEROTOXIN authKW 206252 1% 78% 7
9 PROGUANYLIN authKW 189418 1% 100% 5
10 HEAT STABLE ENTEROTOXIN RECEPTOR authKW 151535 0% 100% 4

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Infectious Diseases 963 11% 0% 88
2 Immunology 655 15% 0% 122
3 Biochemistry & Molecular Biology 632 26% 0% 212
4 Gastroenterology & Hepatology 476 8% 0% 65
5 Biophysics 468 10% 0% 78
6 Physiology 455 9% 0% 73
7 Microbiology 344 10% 0% 80
8 Medicine, Research & Experimental 164 6% 0% 52
9 Cell Biology 160 9% 0% 74
10 Urology & Nephrology 57 3% 0% 26

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PROT YAMADA OKA 32 151535 0% 100% 4
2 MED PATHOL ANAT SCI 113651 0% 100% 3
3 SUPER CIENCIAS BIOMED ISCB 75767 0% 100% 2
4 JOHN M DALTON 50510 0% 67% 2
5 MOL REPROD DEV GENET 42505 3% 5% 23
6 AGR MICROBIOL BIOCHEM 37884 0% 100% 1
7 BAYER TURK 37884 0% 100% 1
8 BIOL MACROMOL ENZYMOL 37884 0% 100% 1
9 BIOMED CLIN UNIT 37884 0% 100% 1
10 COMPLEXO HOSP UNIV SANTIAGO CHUS SERGAS 14 37884 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 INFECTION AND IMMUNITY 7139 9% 0% 71
2 JAPANESE JOURNAL OF MEDICAL SCIENCE & BIOLOGY 5895 1% 2% 9
3 ACTA MICROBIOLOGICA ACADEMIAE SCIENTIARUM HUNGARICAE 1412 0% 2% 2
4 AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY 1168 2% 0% 14
5 CTS-CLINICAL AND TRANSLATIONAL SCIENCE 1098 0% 1% 4
6 JOURNAL OF PEPTIDE RESEARCH 1024 1% 1% 5
7 GASTROENTEROLOGY 902 2% 0% 18
8 BIOMARKERS IN MEDICINE 869 0% 1% 4
9 MICROBIAL PATHOGENESIS 830 1% 0% 8
10 REGULATORY PEPTIDES 786 1% 0% 10

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 GUANYLIN 2606702 11% 79% 87 Search GUANYLIN Search GUANYLIN
2 UROGUANYLIN 2495668 10% 86% 77 Search UROGUANYLIN Search UROGUANYLIN
3 GUANYLYL CYCLASE C 1612330 7% 80% 53 Search GUANYLYL+CYCLASE+C Search GUANYLYL+CYCLASE+C
4 HEAT STABLE ENTEROTOXIN 1515306 7% 67% 60 Search HEAT+STABLE+ENTEROTOXIN Search HEAT+STABLE+ENTEROTOXIN
5 GUANYLATE CYCLASE C 690696 3% 65% 28 Search GUANYLATE+CYCLASE+C Search GUANYLATE+CYCLASE+C
6 E COLI HEAT STABLE ENTEROTOXIN 227302 1% 100% 6 Search E+COLI+HEAT+STABLE+ENTEROTOXIN Search E+COLI+HEAT+STABLE+ENTEROTOXIN
7 GUCY2C 220410 1% 73% 8 Search GUCY2C Search GUCY2C
8 ESCHERICHIA COLI HEAT STABLE ENTEROTOXIN 206252 1% 78% 7 Search ESCHERICHIA+COLI+HEAT+STABLE+ENTEROTOXIN Search ESCHERICHIA+COLI+HEAT+STABLE+ENTEROTOXIN
9 PROGUANYLIN 189418 1% 100% 5 Search PROGUANYLIN Search PROGUANYLIN
10 HEAT STABLE ENTEROTOXIN RECEPTOR 151535 0% 100% 4 Search HEAT+STABLE+ENTEROTOXIN+RECEPTOR Search HEAT+STABLE+ENTEROTOXIN+RECEPTOR

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 FORTE, LR , (2004) UROGUANYLIN AND GUANYLIN PEPTIDES: PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS.PHARMACOLOGY & THERAPEUTICS. VOL. 104. ISSUE 2. P. 137-162 158 79% 83
2 VAANDRAGER, AB , (2002) STRUCTURE AND FUNCTION OF THE HEAT-STABLE ENTEROTOXIN RECEPTOR/GUANYLYL CYCLASE C.MOLECULAR AND CELLULAR BIOCHEMISTRY. VOL. 230. ISSUE 1-2. P. 73-83 96 85% 70
3 BELTOWSKI, J , (2001) GUANYLIN AND RELATED PEPTIDES.JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY. VOL. 52. ISSUE 3. P. 351-375 98 88% 27
4 WEIGLMEIER, PR , ROSCH, P , BERKNER, H , (2010) CURE AND CURSE: E-COLI HEAT-STABLE ENTEROTOXIN AND ITS RECEPTOR GUANYLYL CYCLASE C.TOXINS. VOL. 2. ISSUE 9. P. 2213-2229 85 76% 11
5 FORTE, LR , (1999) GUANYLIN REGULATORY PEPTIDES: STRUCTURES, BIOLOGICAL ACTIVITIES MEDIATED BY CYCLIC GMP AND PATHOBIOLOGY.REGULATORY PEPTIDES. VOL. 81. ISSUE 1-3. P. 25-39 85 90% 82
6 BASU, N , ARSHAD, N , VISWESWARIAH, SS , (2010) RECEPTOR GUANYLYL CYCLASE C (GC-C): REGULATION AND SIGNAL TRANSDUCTION.MOLECULAR AND CELLULAR BIOCHEMISTRY. VOL. 334. ISSUE 1-2. P. 67 -80 91 64% 17
7 SINDIC, A , SCHLATTER, E , (2007) RENAL ELECTROLYTE EFFECTS OF GUANYLIN AND UROGUANYLIN.CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION. VOL. 16. ISSUE 1. P. 10-15 59 89% 16
8 ROZENFELD, J , TAL, O , KLADNITSKY, O , ADLER, L , EFRATI, E , CARRITHERS, SL , ALPER, SL , ZELIKOVIC, I , (2013) PENDRIN, A NOVEL TRANSCRIPTIONAL TARGET OF THE UROGUANYLIN SYSTEM.CELLULAR PHYSIOLOGY AND BIOCHEMISTRY. VOL. 32. ISSUE 7. P. 221-237 69 65% 2
9 QIAN, X , MOSS, NG , FELLNER, RC , TAYLOR-BLAKE, B , GOY, MF , (2011) THE RAT KIDNEY CONTAINS HIGH LEVELS OF PROUROGUANYLIN (THE UROGUANYLIN PRECURSOR) BUT DOES NOT EXPRESS GC-C (THE ENTERIC UROGUANYLIN RECEPTOR).AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY. VOL. 300. ISSUE 2. P. F561 -F573 59 78% 6
10 SINDIC, A , SCHLATTER, E , (2006) CELLULAR EFFECTS OF GUANYLIN AND UROGUANYLIN.JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. VOL. 17. ISSUE 3. P. 607 -616 63 79% 36

Classes with closest relation at Level 1


Rank Class id link
1 9723 ETEC//ENTEROTOXIGENIC ESCHERICHIA COLI//COLONIZATION FACTOR
2 5940 ENTEROTOXIGENIC ESCHERICHIA COLI//F4 FIMBRIAE//K88
3 5760 INTESTINAL SECRETION//SORBIN//E COLI STA
4 16151 CGMP DEPENDENT PROTEIN KINASE//TYPE II CGMP DEPENDENT PROTEIN KINASE//CANC MOL BIOL SECT
5 2353 C TYPE NATRIURETIC PEPTIDE//NATRIURETIC PEPTIDE RECEPTOR//NATRIURETIC PEPTIDES
6 26434 STN GENE//BALI STARLING//SALMONELLA ENTEROTOXIN
7 10086 YC 1//SOLUBLE GUANYLYL CYCLASE//BAY 41 2272
8 3572 CHOLERA TOXIN//HEAT LABILE ENTEROTOXIN//MUCOSAL ADJUVANT
9 9084 CL SECRETION//RAT DISTAL COLON//CHLORIDE SECRETION
10 17256 CDX2//CDX1//CDX

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