Class information for:
Level 1: STEROIDS//STEROIDAL OXIMES//HETEROSTEROIDS

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
13518 831 29.4 65%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
3 4 PLANT SCIENCES//AGRONOMY//FOOD SCIENCE & TECHNOLOGY 1882812
553 3       BRASSINOSTEROIDS//NA K ATPASE//OUABAIN 17999
1738 2             BRASSINOSTEROIDS//24 EPIBRASSINOLIDE//BRASSINOLIDE 6531
13518 1                   STEROIDS//STEROIDAL OXIMES//HETEROSTEROIDS 831

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 STEROIDS journal 281193 22% 4% 182
2 STEROIDAL OXIMES authKW 261288 1% 89% 8
3 HETEROSTEROIDS authKW 248017 1% 75% 9
4 ANDROSTANE DERIVATIVES authKW 235158 1% 80% 8
5 D HOMOSTEROIDS authKW 225055 1% 88% 7
6 PHARMACODYNAM BIOPHARM address 206137 4% 17% 34
7 FUSED STEROIDS authKW 183719 1% 100% 5
8 13 ALPHA ESTRONE authKW 153098 1% 83% 5
9 16 17 SECOSTEROIDS authKW 146976 0% 100% 4
10 17 ALPHA HYDROXYLASE 17 20 LYASE CYP17 INHIBITORS authKW 146976 0% 100% 4

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Chemistry, Medicinal 6214 26% 0% 215
2 Endocrinology & Metabolism 3622 26% 0% 216
3 Chemistry, Organic 3100 28% 0% 235
4 Biochemistry & Molecular Biology 1166 33% 0% 277
5 Chemistry, Multidisciplinary 522 19% 0% 154
6 Crystallography 109 4% 0% 31
7 Pharmacology & Pharmacy 61 8% 0% 64
8 Chemistry, Applied 2 1% 0% 11
9 Oncology 0 3% 0% 22
10 Biophysics 0 1% 0% 11

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PHARMACODYNAM BIOPHARM 206137 4% 17% 34
2 I KUTATELADZE PHARMACEUT CHEM 110232 0% 100% 3
3 IG KUTATELADZE PHARMACEUT CHEM 75009 1% 29% 7
4 HORMONES 56429 2% 12% 13
5 CHEM BIOCHEM ENVIRONM PROTECT 43887 2% 6% 19
6 AFFILIATED HOSP HUANGHE SANMENXIA 36744 0% 100% 1
7 BCH LSCO 36744 0% 100% 1
8 BEIBU GULF MINIST EDUC 36744 0% 100% 1
9 BEIBU GULFENVIRONM CHANGE OURCES UTI 36744 0% 100% 1
10 BIOCHEM ENVIRONM PROTECT 36744 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 STEROIDS 281193 22% 4% 182
2 JOURNAL OF MEDICINAL CHEMISTRY 2828 5% 0% 41
3 ACTA CHIMICA ACADEMIAE SCIENTARIUM HUNGARICAE 2732 1% 1% 5
4 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 2315 3% 0% 24
5 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 2239 3% 0% 24
6 CHEMISTRY OF NATURAL COMPOUNDS 2156 2% 0% 15
7 BIOORGANIC & MEDICINAL CHEMISTRY 1732 3% 0% 25
8 LETTERS IN DRUG DESIGN & DISCOVERY 1731 1% 1% 8
9 ARCHIV DER PHARMAZIE 1651 2% 0% 14
10 CHINESE JOURNAL OF ORGANIC CHEMISTRY 1453 2% 0% 14

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 STEROIDAL OXIMES 261288 1% 89% 8 Search STEROIDAL+OXIMES Search STEROIDAL+OXIMES
2 HETEROSTEROIDS 248017 1% 75% 9 Search HETEROSTEROIDS Search HETEROSTEROIDS
3 ANDROSTANE DERIVATIVES 235158 1% 80% 8 Search ANDROSTANE+DERIVATIVES Search ANDROSTANE+DERIVATIVES
4 D HOMOSTEROIDS 225055 1% 88% 7 Search D+HOMOSTEROIDS Search D+HOMOSTEROIDS
5 FUSED STEROIDS 183719 1% 100% 5 Search FUSED+STEROIDS Search FUSED+STEROIDS
6 13 ALPHA ESTRONE 153098 1% 83% 5 Search 13+ALPHA+ESTRONE Search 13+ALPHA+ESTRONE
7 16 17 SECOSTEROIDS 146976 0% 100% 4 Search 16+17+SECOSTEROIDS Search 16+17+SECOSTEROIDS
8 17 ALPHA HYDROXYLASE 17 20 LYASE CYP17 INHIBITORS 146976 0% 100% 4 Search 17+ALPHA+HYDROXYLASE+17+20+LYASE+CYP17+INHIBITORS Search 17+ALPHA+HYDROXYLASE+17+20+LYASE+CYP17+INHIBITORS
9 HETEROCYCLIC STEROIDS 146972 1% 67% 6 Search HETEROCYCLIC+STEROIDS Search HETEROCYCLIC+STEROIDS
10 ANDROST 5 ENE DERIVATIVES 117579 0% 80% 4 Search ANDROST+5+ENE+DERIVATIVES Search ANDROST+5+ENE+DERIVATIVES

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 YIN, LN , HU, QZ , EMMERICH, J , LO, MMC , METZGER, E , ALI, A , HARTMANN, RW , (2014) NOVEL PYRIDYL- OR ISOQUINOLINYL-SUBSTITUTED INDOLINES AND INDOLES AS POTENT AND SELECTIVE ALDOSTERONE SYNTHASE INHIBITORS.JOURNAL OF MEDICINAL CHEMISTRY. VOL. 57. ISSUE 12. P. 5179 -5189 34 77% 12
2 MOREIRA, VM , SALVADOR, JAR , VASAITIS, TS , NJAR, VCO , (2008) CYP17 INHIBITORS FOR PROSTATE CANCER TREATMENT - AN UPDATE.CURRENT MEDICINAL CHEMISTRY. VOL. 15. ISSUE 9. P. 868-899 73 34% 25
3 ZHU, WX , HU, QZ , HANKE, N , VAN KOPPEN, CJ , HARTMANN, RW , (2014) POTENT 11 BETA-HYDROXYLASE INHIBITORS WITH INVERSE METABOLIC STABILITY IN HUMAN PLASMA AND HEPATIC S9 FRACTIONS TO PROMOTE WOUND HEALING.JOURNAL OF MEDICINAL CHEMISTRY. VOL. 57. ISSUE 18. P. 7811 -7817 29 76% 1
4 HARTMANN, RW , HOYT, S , METZGER, E , LO, MMC , RATCLIFFE, P , BENNETT, J , COOKE, AJ , ALI, A , YIN, LN , HU, QZ , (2015) NOVEL PYRIDYL SUBSTITUTED 4,5-DIHYDRO-[1,2,4]TRIAZOLO[4,3-A]QUINOLINES AS POTENT AND SELECTIVE ALDOSTERONE SYNTHASE INHIBITORS WITH IMPROVED IN VITRO METABOLIC STABILITY.JOURNAL OF MEDICINAL CHEMISTRY. VOL. 58. ISSUE 5. P. 2530 -2537 27 75% 4
5 HARTMANN, RW , HANKE, N , HU, QZ , KUNDE, J , (2015) IDENTIFICATION OF 4-(4-NITRO-2-PHENETHOXYPHENYL)PYRIDINE AS A PROMISING NEW LEAD FOR DISCOVERING INHIBITORS OF BOTH HUMAN AND RAT 11 BETA-HYDROXYLASE.EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. VOL. 96. ISSUE . P. 139 -150 30 70% 2
6 GROMBEIN, CM , HU, QZ , RAU, S , ZIMMER, C , HARTMANN, RW , (2015) HETEROATOM INSERTION INTO 3,4-DIHYDRO-1H-QUINOLIN-2-ONES LEADS TO POTENT AND SELECTIVE INHIBITORS OF HUMAN AND RAT ALDOSTERONE SYNTHASE.EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. VOL. 90. ISSUE . P. 788 -796 31 65% 4
7 GROMBEIN, CM , HU, QZ , HEIM, R , RAU, S , ZIMMER, C , HARTMANN, RW , (2015) 1-PHENYLSULFINYL-3-(PYRIDIN-3-YL)NAPHTHALEN-2-OLS: A NEW CLASS OF POTENT AND SELECTIVE ALDOSTERONE SYNTHASE INHIBITORS.EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. VOL. 89. ISSUE . P. 597 -605 29 63% 2
8 KAKU, T , TSUJIMOTO, S , MATSUNAGA, N , TANAKA, T , HARA, T , YAMAOKA, M , KUSAKA, M , TASAKA, A , (2011) 17,20-LYASE INHIBITORS. PART 3: DESIGN, SYNTHESIS, AND STRUCTURE-ACTIVITY RELATIONSHIPS OF BIPHENYLYLMETHYLIMIDAZOLE DERIVATIVES AS NOVEL 17,20-LYASE INHIBITORS.BIOORGANIC & MEDICINAL CHEMISTRY. VOL. 19. ISSUE 7. P. 2428 -2442 29 67% 5
9 LEROUX, F , (2005) INHIBITION OF P450 17 AS A NEW STRATEGY FOR THE TREATMENT OF PROSTATE CANCER.CURRENT MEDICINAL CHEMISTRY. VOL. 12. ISSUE 14. P. 1623-1629 31 72% 25
10 HU, QZ , YIN, LN , HARTMANN, RW , (2014) ALDOSTERONE SYNTHASE INHIBITORS AS PROMISING TREATMENTS FOR MINERALOCORTICOID DEPENDENT CARDIOVASCULAR AND RENAL DISEASES.JOURNAL OF MEDICINAL CHEMISTRY. VOL. 57. ISSUE 12. P. 5011 -5022 33 47% 16

Classes with closest relation at Level 1


Rank Class id link
1 8508 HUMAN PLACENTAL MICROSOMES//19 OXYGENATION//SUICIDE SUBSTRATE
2 24051 PENTACYCLIC STEROIDS//IMIDE REDUCTION//13 16 DIAZASTEROIDS
3 27087 HOMO AZA STEROIDAL ESTERS//STEROIDAL ESTERS//HOMO AZA STEROIDS
4 32550 1 3 BIPOLAR CYCLOADDITION OF NITRILE OXIDES//17 20 DIOLS//17 ALPHA PREGNA 2 4 DIEN 2 3 DISOXAZOL 17 BETA OL
5 5097 AROMATASE INHIBITORS//ANASTROZOLE//EXEMESTANE
6 13102 17 BETA HYDROXYSTEROID DEHYDROGENASE//17 BETA HSD2//17 BETA HSD1
7 10101 ANTLEY BIXLER SYNDROME//ADRENARCHE//17 ALPHA HYDROXYLASE DEFICIENCY
8 17767 PENTARANES//GRP CHEM STEROIDS OXYLIPINES//PROGESTERONE ANALOGS
9 22853 14 ALPHA 15 ALPHA METHYLENE ESTRADIOL//SIMMONS SMITH ADDITION//SPIRO STEROIDS
10 5864 FINASTERIDE//5 ALPHA REDUCTASE//5 ALPHA REDUCTASE INHIBITORS

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