Class information for:
Level 1: PICTET SPENGLER REACTION//PICTET SPENGLER//TETRAHYDRO BETA CARBOLINE

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
12350 912 27.8 56%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
3 4 PLANT SCIENCES//AGRONOMY//FOOD SCIENCE & TECHNOLOGY 1882812
409 3       BERBERINE//ALKALOIDS//RUTACEAE 29426
2345 2             AMARYLLIDACEAE//TRABECTEDIN//AMARYLLIDACEAE ALKALOIDS 4395
12350 1                   PICTET SPENGLER REACTION//PICTET SPENGLER//TETRAHYDRO BETA CARBOLINE 912

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PICTET SPENGLER REACTION authKW 639852 6% 33% 58
2 PICTET SPENGLER authKW 164804 2% 31% 16
3 TETRAHYDRO BETA CARBOLINE authKW 150006 2% 20% 22
4 CALYCOTOMINE authKW 107135 0% 80% 4
5 TETRAHYDROISOQUINOLINE authKW 95174 4% 9% 32
6 1 ARYLTETRAHYDROISOQUINOLINE ALKALOIDS authKW 66961 0% 100% 2
7 1 BENZYLTETRA HYDROISOQUINOLINES authKW 66961 0% 100% 2
8 CIENCIAS QUIM ARTADO 644 address 66961 0% 100% 2
9 DIFORMAMIDES authKW 66961 0% 100% 2
10 N TOSYLIMINIUM IONS authKW 66961 0% 100% 2

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Chemistry, Organic 20342 66% 0% 606
2 Chemistry, Medicinal 931 10% 0% 92
3 Chemistry, Multidisciplinary 915 22% 0% 205
4 Crystallography 284 5% 0% 49
5 Chemistry, Inorganic & Nuclear 102 5% 0% 44
6 Pharmacology & Pharmacy 28 6% 0% 55
7 Chemistry, Applied 26 2% 0% 22
8 Chemistry, Physical 8 6% 0% 51
9 Plant Sciences 1 2% 0% 21
10 Spectroscopy 0 1% 0% 8

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CIENCIAS QUIM ARTADO 644 66961 0% 100% 2
2 ANALYT S YOKOGAWA KU 33480 0% 100% 1
3 ASYMMET SYNTH 33480 0% 100% 1
4 CHIM SESO 3 33480 0% 100% 1
5 CIC QUIM CIENCIAS EXATAS 33480 0% 100% 1
6 CIENCIAS CRISTALOGR MINERAL 33480 0% 100% 1
7 CIENCIAS ORGAN 33480 0% 100% 1
8 CIENCIAS QUIM INORGAN ORGAN ANALIT 33480 0% 100% 1
9 CIENCIAS QUIM ORGAN DO 644 33480 0% 100% 1
10 CIENCIAS QUIM ORGAN POB 644 33480 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 HETEROCYCLES 14258 8% 1% 75
2 TETRAHEDRON-ASYMMETRY 5947 5% 0% 43
3 TETRAHEDRON LETTERS 5774 12% 0% 113
4 TETRAHEDRON 4498 8% 0% 71
5 JOURNAL OF HETEROCYCLIC CHEMISTRY 3113 4% 0% 32
6 POLISH JOURNAL OF PHARMACOLOGY AND PHARMACY 2745 1% 1% 8
7 JOURNAL OF COMBINATORIAL CHEMISTRY 2435 1% 1% 10
8 SYNTHETIC COMMUNICATIONS 2382 4% 0% 32
9 JOURNAL OF ORGANIC CHEMISTRY 2365 7% 0% 61
10 EUROPEAN JOURNAL OF ORGANIC CHEMISTRY 1938 3% 0% 27

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 PICTET SPENGLER REACTION 639852 6% 33% 58 Search PICTET+SPENGLER+REACTION Search PICTET+SPENGLER+REACTION
2 PICTET SPENGLER 164804 2% 31% 16 Search PICTET+SPENGLER Search PICTET+SPENGLER
3 TETRAHYDRO BETA CARBOLINE 150006 2% 20% 22 Search TETRAHYDRO+BETA+CARBOLINE Search TETRAHYDRO+BETA+CARBOLINE
4 CALYCOTOMINE 107135 0% 80% 4 Search CALYCOTOMINE Search CALYCOTOMINE
5 TETRAHYDROISOQUINOLINE 95174 4% 9% 32 Search TETRAHYDROISOQUINOLINE Search TETRAHYDROISOQUINOLINE
6 1 ARYLTETRAHYDROISOQUINOLINE ALKALOIDS 66961 0% 100% 2 Search 1+ARYLTETRAHYDROISOQUINOLINE+ALKALOIDS Search 1+ARYLTETRAHYDROISOQUINOLINE+ALKALOIDS
7 1 BENZYLTETRA HYDROISOQUINOLINES 66961 0% 100% 2 Search 1+BENZYLTETRA+HYDROISOQUINOLINES Search 1+BENZYLTETRA+HYDROISOQUINOLINES
8 DIFORMAMIDES 66961 0% 100% 2 Search DIFORMAMIDES Search DIFORMAMIDES
9 N TOSYLIMINIUM IONS 66961 0% 100% 2 Search N+TOSYLIMINIUM+IONS Search N+TOSYLIMINIUM+IONS
10 PYRIDO3 4 BINDOLE DERIVATIVES 66961 0% 100% 2 Search PYRIDO3+4+BINDOLE+DERIVATIVES Search PYRIDO3+4+BINDOLE+DERIVATIVES

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 YOUN, SW , (2006) THE PICTET-SPENGLER REACTION: EFFICIENT CARBON-CARBON BOND FORMING REACTION IN HETEROCYCLIC SYNTHESIS.ORGANIC PREPARATIONS AND PROCEDURES INTERNATIONAL. VOL. 38. ISSUE 6. P. 505-+ 127 45% 41
2 CHRZANOWSKA, M , ROZWADOWSKA, MD , (2004) ASYMMETRIC SYNTHESIS OF ISOQUINOLINE ALKALOIDS.CHEMICAL REVIEWS. VOL. 104. ISSUE 7. P. 3341 -3370 58 43% 465
3 INGALLINA, C , D'ACQUARICA, I , DELLE MONACHE, G , GHIRGA, F , QUAGLIO, D , GHIRGA, P , BERARDOZZI, S , MARKOVIC, V , BOTTA, B , (2016) THE PICTET-SPENGLER REACTION STILL ON STAGE.CURRENT PHARMACEUTICAL DESIGN. VOL. 22. ISSUE 12. P. 1808 -1850 67 30% 2
4 DALPOZZO, R , (2016) THE CHIRAL POOL IN THE PICTET-SPENGLER REACTION FOR THE SYNTHESIS OF BETA-CARBOLINES.MOLECULES. VOL. 21. ISSUE 6. P. - 32 46% 1
5 STOCKIGT, J , ANTONCHICK, AP , WU, FR , WALDMANN, H , (2011) THE PICTET-SPENGLER REACTION IN NATURE AND IN ORGANIC CHEMISTRY.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. VOL. 50. ISSUE 37. P. 8538 -8564 44 25% 198
6 CZARNOCKI, Z , SIWICKA, A , SZAWKALO, J , (2005) SELECTED RECENT ADVANCES IN THE STEREOSELECTIVE SYNTHESIS OF ISOQUINOLINE AND BETA-CARBOLINE DERIVATIVES WITH THE USE OF CHIRAL AUXILIARIES OF NATURAL ORIGIN.CURRENT ORGANIC SYNTHESIS. VOL. 2. ISSUE 3. P. 301 -331 38 47% 28
7 VICARIO, JL , BADIA, D , CARRILLO, L , ETXEBARRIA, J , (2003) ALPHA-AMINO ACIDS AND DERIVATIVES IN THE ASYMMETRIC SYNTHESIS OF TETRAHYDROISOQUINOLINE ALKALOIDS.CURRENT ORGANIC CHEMISTRY. VOL. 7. ISSUE 18. P. 1775 -1792 49 38% 23
8 KUNDU, B , AGARWAL, PK , SHARMA, SK , SAWANT, D , MANDADAPU, AK , SAIFUDDIN, M , GUPTA, S , (2012) PICTET-SPENGLER REACTION REVISITED: ENGINEERING OF TETHERD BIHETEROCYCLES INTO ANNULATED POLYHETEROCYCLES.CURRENT ORGANIC SYNTHESIS. VOL. 9. ISSUE 3. P. 357 -376 38 38% 9
9 BRACCA, ABJ , KAUFMAN, TS , (2004) SYNTHETIC APPROACHES TO CARNEGINE, A SIMPLE TETRAHYDROISOQUINOLINE ALKALOID.TETRAHEDRON. VOL. 60. ISSUE 47. P. 10575 -10610 44 39% 31
10 YAN, S , LAM, KT , MO, KT , WONG, WY , CHAN, WH , LEE, AWM , (2005) CHIRAL ACETYLENIC SULFOXIDE IN ORGANIC SYNTHESIS: ADDITION OF CHIRAL SECONDARY AMINES.LETTERS IN ORGANIC CHEMISTRY. VOL. 2. ISSUE 1. P. 33-36 22 79% 3

Classes with closest relation at Level 1


Rank Class id link
1 27715 NOREPINEPHRINE POTENTIATOR//REDUCTIVE N METHYLATION//TETRAHYDROISOQUINOLIN 4 OL
2 19544 RENIERAMYCIN//QUINOCARCIN//SAFRAMYCIN
3 14447 ERYTHRINA ALKALOID//DIOXOPYRROLINE//ERYTHRINA VELUTINA
4 23853 STEPWISE 33 ANNULATION//CINCHOLOIPON//OXAZOLOISOQUINOLINONES
5 8632 BETA CARBOLINE//HARMINE//NORHARMAN
6 25887 MOBILE PHASE SELECTION//HOMOPHTHALIC ANHYDRIDE//CIS ISOQUINOLONIC ACIDS
7 28309 BHUTANESE TRADITIONAL MEDICINE//FUMARIA//MANJONG SORIG PHARMACEUT
8 25388 RONGALITE//DIVERSITY ORIENTED APPROACH//BENZOCTAMINE
9 16574 BISTRIMETHYLSILYLKETENE ACETALS//N ACTIVATION//GAMMA AND DELTA LACTONES
10 3507 APORPHINE ALKALOIDS//APORPHINE//ANNONACEAE

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