Class information for:
Level 1: SHIKIMATE KINASE//SHIKIMIC ACID//SHIKIMATE PATHWAY

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
12299 916 35.8 69%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
278 3       CORYNEBACTERIUM GLUTAMICUM//ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY//BIOCHEMISTRY & MOLECULAR BIOLOGY 43163
3021 2             SHIKIMATE PATHWAY//CHORISMATE MUTASE//ANTHRANILATE SYNTHASE 2519
12299 1                   SHIKIMATE KINASE//SHIKIMIC ACID//SHIKIMATE PATHWAY 916

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SHIKIMATE KINASE authKW 725929 3% 78% 28
2 SHIKIMIC ACID authKW 685201 7% 34% 61
3 SHIKIMATE PATHWAY authKW 648582 7% 32% 60
4 DEHYDROQUINASE authKW 466677 2% 100% 14
5 CHORISMATE SYNTHASE authKW 387878 2% 73% 16
6 SHIKIMATE DEHYDROGENASE authKW 360350 2% 54% 20
7 TAMIFLU authKW 303845 3% 33% 28
8 DEHYDROQUINATE SYNTHASE authKW 171431 1% 86% 6
9 DEHYDROQUINATE DEHYDRATASE authKW 166670 1% 100% 5
10 AROE authKW 138890 1% 83% 5

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Chemistry, Organic 1827 21% 0% 194
2 Biotechnology & Applied Microbiology 1558 18% 0% 169
3 Biochemistry & Molecular Biology 1126 32% 0% 289
4 Chemistry, Medicinal 399 7% 0% 63
5 Chemistry, Multidisciplinary 261 14% 0% 125
6 Microbiology 205 8% 0% 70
7 Biophysics 194 6% 0% 58
8 Biochemical Research Methods 161 5% 0% 49
9 Crystallography 48 3% 0% 24
10 Genetics & Heredity 37 4% 0% 38

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 INGN CELULAR BIOCATALISIS 101638 3% 11% 28
2 PEQUISAS BIOL MOL FUNC 66668 0% 100% 2
3 ESTRUCT MACROMOL 49485 1% 21% 7
4 NAT PROD ORGAN SYNTH UNIT NPOS 48481 0% 36% 4
5 BIOL INTEGRAT PLANTAS MICROORGANISMOS 44444 0% 67% 2
6 PESQUISA BIOL MOL FUNCT 44444 0% 67% 2
7 SINGULAR INVEST QUIM BIOL MAT MOL CIQUS 44420 2% 10% 14
8 BIO PLICAT SYST ENGINE 33334 0% 100% 1
9 BIOINFORMAT MODELAGEM SIMULACAO BIOSSIST 33334 0% 100% 1
10 BIOINFORMAT MODELAGEN SIMULACAO BIOSSISTEMA 33334 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MICROBIAL CELL FACTORIES 13017 3% 2% 23
2 CHEMMEDCHEM 2829 2% 1% 14
3 JOURNAL OF MOLECULAR MICROBIOLOGY AND BIOTECHNOLOGY 2641 1% 1% 8
4 METABOLIC ENGINEERING 2522 1% 1% 9
5 BIOCHEMICAL JOURNAL 1513 4% 0% 37
6 ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY 740 1% 0% 10
7 BIOTECHNOLOGY AND BIOENGINEERING 703 2% 0% 16
8 BIOTECHNOLOGY PROGRESS 702 1% 0% 10
9 MOLECULAR & GENERAL GENETICS 660 1% 0% 7
10 JOURNAL OF ORGANIC CHEMISTRY 579 3% 0% 31

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 SHIKIMATE KINASE 725929 3% 78% 28 Search SHIKIMATE+KINASE Search SHIKIMATE+KINASE
2 SHIKIMIC ACID 685201 7% 34% 61 Search SHIKIMIC+ACID Search SHIKIMIC+ACID
3 SHIKIMATE PATHWAY 648582 7% 32% 60 Search SHIKIMATE+PATHWAY Search SHIKIMATE+PATHWAY
4 DEHYDROQUINASE 466677 2% 100% 14 Search DEHYDROQUINASE Search DEHYDROQUINASE
5 CHORISMATE SYNTHASE 387878 2% 73% 16 Search CHORISMATE+SYNTHASE Search CHORISMATE+SYNTHASE
6 SHIKIMATE DEHYDROGENASE 360350 2% 54% 20 Search SHIKIMATE+DEHYDROGENASE Search SHIKIMATE+DEHYDROGENASE
7 TAMIFLU 303845 3% 33% 28 Search TAMIFLU Search TAMIFLU
8 DEHYDROQUINATE SYNTHASE 171431 1% 86% 6 Search DEHYDROQUINATE+SYNTHASE Search DEHYDROQUINATE+SYNTHASE
9 DEHYDROQUINATE DEHYDRATASE 166670 1% 100% 5 Search DEHYDROQUINATE+DEHYDRATASE Search DEHYDROQUINATE+DEHYDRATASE
10 AROE 138890 1% 83% 5 Search AROE Search AROE

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 NIE, LD , WANG, FF , DING, W , SHI, XX , LU, X , (2013) A NOVEL AZIDE-FREE ASYMMETRIC SYNTHESIS OF OSELTAMIVIR PHOSPHATE (TAMIFLU) STARTING FROM ROCHE'S EPOXIDE.TETRAHEDRON-ASYMMETRY. VOL. 24. ISSUE 11. P. 638 -642 61 86% 8
2 MUKAIYAMA, T , ISHIKAWA, H , KOSHINO, H , HAYASHI, Y , (2013) ONE-POT SYNTHESIS OF (-)-OSELTAMIVIR AND MECHANISTIC INSIGHTS INTO THE ORGANOCATALYZED MICHAEL REACTION.CHEMISTRY-A EUROPEAN JOURNAL. VOL. 19. ISSUE 52. P. 17789 -17800 60 77% 28
3 NIE, LD , DING, W , SHI, XX , QUAN, N , LU, X , (2012) A NOVEL AND HIGH-YIELDING ASYMMETRIC SYNTHESIS OF OSELTAMIVIR PHOSPHATE (TAMIFLU) STARTING FROM (-)-SHIKIMIC ACID.TETRAHEDRON-ASYMMETRY. VOL. 23. ISSUE 10. P. 742 -747 58 91% 10
4 DUCATI, RG , BASSO, LA , SANTOS, DS , (2007) MYCOBACTERIAL SHIKIMATE PATHWAY ENZYMES AS TARGETS FOR DRUG DESIGN.CURRENT DRUG TARGETS. VOL. 8. ISSUE 3. P. 423-435 86 61% 33
5 FURUTACHI, M , KUMAGAI, N , WATANABE, T , SHIBASAKI, M , (2014) CHROMATOGRAPHY-FREE SYNTHESIS OF COREY'S INTERMEDIATE FOR TAMIFLU.TETRAHEDRON. VOL. 70. ISSUE 47. P. 9113 -9117 48 86% 1
6 PEEK, J , CHRISTENDAT, D , (2015) THE SHIKIMATE DEHYDROGENASE FAMILY: FUNCTIONAL DIVERSITY WITHIN A CONSERVED STRUCTURAL AND MECHANISTIC FRAMEWORK.ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. VOL. 566. ISSUE . P. 85 -99 64 62% 1
7 TRAJKOVIC, M , FERJANCIC, Z , SAICIC, RN , (2013) FORMAL SYNTHESIS OF (-)-OSELTAMIVIR PHOSPHATE.SYNTHESIS-STUTTGART. VOL. 45. ISSUE 3. P. 389 -395 50 78% 6
8 DEV, A , TAPAS, S , PRATAP, S , KUMAR, P , (2012) STRUCTURE AND FUNCTION OF ENZYMES OF SHIKIMATE PATHWAY.CURRENT BIOINFORMATICS. VOL. 7. ISSUE 4. P. 374 -391 64 64% 1
9 NIE, LD , SHI, XX , QUAN, N , WANG, FF , LU, X , (2011) NOVEL ASYMMETRIC SYNTHESIS OF OSELTAMIVIR PHOSPHATE (TAMIFLU) FROM (-)-SHIKIMIC ACID VIA CYCLIC SULFITE INTERMEDIATES.TETRAHEDRON-ASYMMETRY. VOL. 22. ISSUE 16-17. P. 1692 -1699 47 84% 9
10 GONZALEZ-BELLO, C , (2016) INHIBITION OF SHIKIMATE KINASE AND TYPE II DEHYDROQUINASE FOR ANTIBIOTIC DISCOVERY: STRUCTURE-BASED DESIGN AND SIMULATION STUDIES.CURRENT TOPICS IN MEDICINAL CHEMISTRY. VOL. 16. ISSUE 9. P. 960 -977 47 76% 0

Classes with closest relation at Level 1


Rank Class id link
1 9861 ANTHRANILATE SYNTHASE//CHORISMATE MUTASE//CHORISMATE
2 19782 KDO8P SYNTHASE//3 DEOXY D ARABINO HEPTULOSONATE 7 PHOSPHATE SYNTHASE//KDO8PS
3 8404 GLYPHOSATE RESISTANCE//GLYPHOSATE//EPSPS
4 9728 CARBASUGARS//VALIENAMINE//CYCLITOLS
5 4282 CORYNEBACTERIUM GLUTAMICUM//BIOTECHNOL 1//CHAIR GENET PROKARYOTES
6 1978 NEURAMINIDASE INHIBITORS//OSELTAMIVIR//ZANAMIVIR
7 16509 TYRR//LONG ACCURATE PCR//BACILLUS SUBTILIS GENOME SEQUENCING
8 6253 METABOLIC ENGINEERING//SYNTHETIC BIOLOGY//BIORENEWABLE CHEMICALS
9 21261 2 DEOXY SCYLLO INOSOSE SYNTHASE//BUTIROSIN//STREPTOMYCES KANAMYCETICUS
10 25859 PENEHYCLIDINE HYDROCHLORIDE//PHENCYNONATE//BISDIHYDROPYRANS

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