Class information for:
Level 1: GM CSF RECEPTOR//CYTOKINE RECEPTOR//INTERLEUKIN 5 RECEPTOR

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
12037 936 44.5 88%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
51 3       HEMATOLOGY//BONE MARROW TRANSPLANTATION//BLOOD 91443
209 2             EXPERIMENTAL HEMATOLOGY//THROMBOPOIETIN//HEMATOLOGY 20851
12037 1                   GM CSF RECEPTOR//CYTOKINE RECEPTOR//INTERLEUKIN 5 RECEPTOR 936

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 GM CSF RECEPTOR authKW 278308 2% 37% 23
2 CYTOKINE RECEPTOR address 163089 2% 33% 15
3 INTERLEUKIN 5 RECEPTOR authKW 155425 1% 53% 9
4 INTERLEUKIN 5 authKW 129372 5% 8% 49
5 EOSINOPHIL DIFFERENTIATION FACTOR authKW 104388 0% 80% 4
6 IL 5 RECEPTOR authKW 99896 1% 44% 7
7 IL 3 RECEPTOR authKW 86981 1% 33% 8
8 HUMAN IMMUNOL address 73489 4% 7% 33
9 COMMON BETA SUBUNIT authKW 73397 0% 75% 3
10 HUMAN INTERLEUKIN 5 authKW 73397 0% 75% 3

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Hematology 4747 22% 0% 207
2 Immunology 2411 25% 0% 237
3 Biochemistry & Molecular Biology 2206 42% 0% 389
4 Cell Biology 1731 23% 0% 217
5 Allergy 389 3% 0% 30
6 Medicine, Research & Experimental 211 7% 0% 63
7 Biophysics 136 5% 0% 51
8 Oncology 95 7% 0% 69
9 Genetics & Heredity 82 5% 0% 50
10 Biochemical Research Methods 64 4% 0% 35

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 CYTOKINE RECEPTOR 163089 2% 33% 15
2 HUMAN IMMUNOL 73489 4% 7% 33
3 AJ DREXEL BASIC PL PROT SCI 65239 0% 50% 4
4 HANSON CANC 50593 2% 10% 15
5 AUSTRALIAN CANC FDN RAT DRUG DISCOVERY 43494 0% 67% 2
6 STELLAR CHANCE S 913 43494 0% 67% 2
7 ALBERTA BONE MARROW STEM CELL TRANSPLANT PROGRAM 32622 0% 100% 1
8 ALLERGY RHEUMATOL SECT 32622 0% 100% 1
9 BCM 285 32622 0% 100% 1
10 BIOCHEM 332 N LAUDERDALE ST 32622 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 BLOOD 12965 13% 0% 117
2 CYTOKINE 2365 2% 0% 18
3 JOURNAL OF BIOLOGICAL CHEMISTRY 2131 11% 0% 102
4 GROWTH FACTORS 1999 1% 1% 7
5 HYBRIDOMA 1861 1% 1% 11
6 HEMATOLOGIC PATHOLOGY 1479 0% 2% 2
7 EXPERIMENTAL HEMATOLOGY 1438 2% 0% 16
8 INTERNATIONAL IMMUNOLOGY 1150 1% 0% 12
9 EMBO JOURNAL 889 2% 0% 22
10 LEUKEMIA 824 1% 0% 14

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 GM CSF RECEPTOR 278308 2% 37% 23 Search GM+CSF+RECEPTOR Search GM+CSF+RECEPTOR
2 INTERLEUKIN 5 RECEPTOR 155425 1% 53% 9 Search INTERLEUKIN+5+RECEPTOR Search INTERLEUKIN+5+RECEPTOR
3 CYTOKINE RECEPTOR 148065 4% 12% 38 Search CYTOKINE+RECEPTOR Search CYTOKINE+RECEPTOR
4 INTERLEUKIN 5 129372 5% 8% 49 Search INTERLEUKIN+5 Search INTERLEUKIN+5
5 EOSINOPHIL DIFFERENTIATION FACTOR 104388 0% 80% 4 Search EOSINOPHIL+DIFFERENTIATION+FACTOR Search EOSINOPHIL+DIFFERENTIATION+FACTOR
6 IL 5 RECEPTOR 99896 1% 44% 7 Search IL+5+RECEPTOR Search IL+5+RECEPTOR
7 IL 3 RECEPTOR 86981 1% 33% 8 Search IL+3+RECEPTOR Search IL+3+RECEPTOR
8 COMMON BETA SUBUNIT 73397 0% 75% 3 Search COMMON+BETA+SUBUNIT Search COMMON+BETA+SUBUNIT
9 HUMAN INTERLEUKIN 5 73397 0% 75% 3 Search HUMAN+INTERLEUKIN+5 Search HUMAN+INTERLEUKIN+5
10 B CELL GROWTH FACTOR II 65243 0% 100% 2 Search B+CELL+GROWTH+FACTOR+II Search B+CELL+GROWTH+FACTOR+II

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 BROUGHTON, SE , DHAGAT, U , HERCUS, TR , NERO, TL , GRIMBALDESTON, MA , BONDER, CS , LOPEZ, AF , PARKER, MW , (2012) THE GM-CSF/IL-3/IL-5 CYTOKINE RECEPTOR FAMILY: FROM LIGAND RECOGNITION TO INITIATION OF SIGNALING.IMMUNOLOGICAL REVIEWS. VOL. 250. ISSUE . P. 277 -302 102 44% 41
2 HERCUS, TR , DHAGAT, U , KAN, WLT , BROUGHTON, SE , NERO, TL , PERUGINI, M , SANDOW, JJ , D'ANDREA, RJ , EKERT, PG , HUGHES, T , ET AL (2013) SIGNALLING BY THE BETA C FAMILY OF CYTOKINES.CYTOKINE & GROWTH FACTOR REVIEWS. VOL. 24. ISSUE 3. P. 189-201 75 41% 16
3 BROUGHTON, SE , NERO, TL , DHAGAT, U , KAN, WL , HERCUS, TR , TVOROGOV, D , LOPEZ, AF , PARKER, MW , (2015) THE BETA C RECEPTOR FAMILY - STRUCTURAL INSIGHTS AND THEIR FUNCTIONAL IMPLICATIONS.CYTOKINE. VOL. 74. ISSUE 2. P. 247 -258 53 52% 8
4 MIYAJIMA, A , MUI, ALF , OGOROCHI, T , SAKAMAKI, K , (1993) RECEPTORS FOR GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR, INTERLEUKIN-3, AND INTERLEUKIN-5.BLOOD. VOL. 82. ISSUE 7. P. 1960 -1974 75 46% 376
5 MURPHY, JM , YOUNG, IG , (2006) IL-3, IL-5, AND GM-CSF SIGNALING: CRYSTAL STRUCTURE OF THE HUMAN BETA-COMMON RECEPTOR.INTERLEUKINS. VOL. 74. ISSUE . P. 1-30 53 58% 29
6 ZAKS-ZILBERMAN, M , HARRINGTON, AE , ISHINO, T , CHAIKEN, IM , (2008) INTERLEUKIN-5 RECEPTOR SUBUNIT OLIGOMERIZATION AND REARRANGEMENT REVEALED BY FLUORESCENCE RESONANCE ENERGY TRANSFER IMAGING.JOURNAL OF BIOLOGICAL CHEMISTRY. VOL. 283. ISSUE 19. P. 13398-13406 42 67% 15
7 D'ANDREA, RJ , GONDA, TJ , (2000) A MODEL FOR ASSEMBLY AND ACTIVATION OF THE GM-CSF, IL-3 AND IL-5 RECEPTORS: INSIGHTS FROM ACTIVATED MUTANTS OF THE COMMON BETA SUBUNIT.EXPERIMENTAL HEMATOLOGY. VOL. 28. ISSUE 3. P. 231 -243 60 55% 31
8 BROUGHTON, SE , HERCUS, TR , NERO, TL , DOTTORE, M , MCCLURE, BJ , DHAGAT, U , TAING, H , GORMAN, MA , KING-SCOTT, J , LOPEZ, AF , ET AL (2016) CONFORMATIONAL CHANGES IN THE GM-CSF RECEPTOR SUGGEST A MOLECULAR MECHANISM FOR AFFINITY CONVERSION AND RECEPTOR SIGNALING.STRUCTURE. VOL. 24. ISSUE 8. P. 1271 -1281 25 76% 2
9 HANSEN, G , HERCUS, TR , MCCLURE, BJ , STOMSKI, FC , DOTTORE, M , POWELL, J , RAMSHAW, H , WOODCOCK, JM , XU, YB , GUTHRIDGE, M , ET AL (2008) THE STRUCTURE OF THE GM-CSF RECEPTOR COMPLEX REVEALS A DISTINCT MODE OF CYTOKINE RECEPTOR ACTIVATION.CELL. VOL. 134. ISSUE 3. P. 496-507 33 63% 115
10 KUSANO, S , KUKIMOTO-NIINO, M , HINO, N , OHSAWA, N , IKUTANI, M , TAKAKI, S , SAKAMOTO, K , HARA-YOKOYAMA, M , SHIROUZU, M , TAKATSU, K , ET AL (2012) STRUCTURAL BASIS OF INTERLEUKIN-5 DIMER RECOGNITION BY ITS A RECEPTOR.PROTEIN SCIENCE. VOL. 21. ISSUE 6. P. 850 -864 35 57% 9

Classes with closest relation at Level 1


Rank Class id link
1 17868 BLAST COLONIES//FDC P2//HEMATOPOIETIC REGULATORS
2 2206 G CSF//GM CSF//GRANULOCYTE COLONY STIMULATING FACTOR
3 25493 LEUKEMIA STEM CELLS//LEUKEMIC STEM CELLS//CD123
4 7880 ERYTHROPOIETIN RECEPTOR//ERYTHROPOIESIS//ERYTHROBLASTIC ISLAND
5 15258 PULMONARY ALVEOLAR PROTEINOSIS//WHOLE LUNG LAVAGE//ALVEOLAR PROTEINOSIS
6 5436 INTERLEUKIN 5//IL 5//EOSINOPHILS
7 1702 EOSINOPHILS//EOTAXIN//CCR3
8 27457 C FES//FER//ENDOTHELIAL CELL BIOL
9 18423 PIECEMEAL DEGRANULATION//ACUTE BASOPHILIC LEUKEMIA//CHARCOT LEYDEN CRYSTALS
10 5895 MOL TUMOR BIOL//CELLULAR GENE THER IES//INTERLEUKIN 13

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