Class information for:
Level 1: TEV PROTEASE//FUSION TAG//AFFINITY TAG

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
11813 952 36.1 86%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
0 4 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//ONCOLOGY 4064930
478 3       PHAGE DISPLAY//CELL FREE PROTEIN SYNTHESIS//ANTIBODY ENGINEERING 23687
1537 2             CELL FREE PROTEIN SYNTHESIS//INTEIN//PROTEIN SPLICING 7453
11813 1                   TEV PROTEASE//FUSION TAG//AFFINITY TAG 952

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 TEV PROTEASE authKW 321607 2% 53% 19
2 FUSION TAG authKW 241649 2% 42% 18
3 AFFINITY TAG authKW 224783 3% 26% 27
4 SOLUBILITY ENHANCER authKW 216804 1% 52% 13
5 PROT ENGN SECT address 208464 1% 50% 13
6 STRUCTURAL GENOMICS authKW 136759 5% 9% 48
7 PROTEIN EXPRESSION AND PURIFICATION journal 136063 15% 3% 140
8 TOBACCO ETCH VIRUS PROTEASE authKW 128286 1% 50% 8
9 TAG REMOVAL authKW 120886 1% 54% 7
10 POLY HISTIDINE FUSION TAG CLEAVAGE authKW 96220 0% 100% 3

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Biochemical Research Methods 18133 46% 0% 436
2 Biochemistry & Molecular Biology 6733 68% 0% 647
3 Biotechnology & Applied Microbiology 5118 32% 0% 300
4 Biophysics 2062 18% 0% 167
5 Crystallography 582 7% 0% 69
6 Cell Biology 97 7% 0% 69
7 Chemistry, Analytical 94 6% 0% 55
8 Mathematical & Computational Biology 90 2% 0% 20
9 Genetics & Heredity 34 4% 0% 38
10 Multidisciplinary Sciences 7 1% 0% 7

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PROT ENGN SECT 208464 1% 50% 13
2 ISRAEL STRUCT PROTEOM 82468 1% 43% 6
3 PLANT BIOMED 64147 0% 100% 2
4 SECSG 64147 0% 100% 2
5 SERV TECHNOL UNIT 64147 0% 100% 2
6 UNIT VIRUS HOST CELL INTERACTUMI3265 57730 0% 60% 3
7 ARCHITECTURE FONCT MACROMOL BIOL UMR 6098 51313 0% 40% 4
8 MACROMOL CRYSTALLOG 45885 3% 5% 27
9 EMBL GRENOBLE 42763 0% 67% 2
10 HIGH THROUGHPUT PROT 42763 0% 67% 2

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PROTEIN EXPRESSION AND PURIFICATION 136063 15% 3% 140
2 PROTEIN SCIENCE 11247 5% 1% 47
3 BIOTECHNIQUES 8003 4% 1% 39
4 ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY 7382 2% 1% 17
5 NATURE STRUCTURAL BIOLOGY 5185 2% 1% 16
6 ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY 4892 3% 1% 26
7 JOURNAL OF STRUCTURAL BIOLOGY 2060 2% 0% 15
8 ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS 2037 1% 0% 14
9 MICROBIAL CELL FACTORIES 1907 1% 1% 9
10 ANALYTICAL BIOCHEMISTRY 1522 3% 0% 30

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 TEV PROTEASE 321607 2% 53% 19 Search TEV+PROTEASE Search TEV+PROTEASE
2 FUSION TAG 241649 2% 42% 18 Search FUSION+TAG Search FUSION+TAG
3 AFFINITY TAG 224783 3% 26% 27 Search AFFINITY+TAG Search AFFINITY+TAG
4 SOLUBILITY ENHANCER 216804 1% 52% 13 Search SOLUBILITY+ENHANCER Search SOLUBILITY+ENHANCER
5 STRUCTURAL GENOMICS 136759 5% 9% 48 Search STRUCTURAL+GENOMICS Search STRUCTURAL+GENOMICS
6 TOBACCO ETCH VIRUS PROTEASE 128286 1% 50% 8 Search TOBACCO+ETCH+VIRUS+PROTEASE Search TOBACCO+ETCH+VIRUS+PROTEASE
7 TAG REMOVAL 120886 1% 54% 7 Search TAG+REMOVAL Search TAG+REMOVAL
8 POLY HISTIDINE FUSION TAG CLEAVAGE 96220 0% 100% 3 Search POLY+HISTIDINE+FUSION+TAG+CLEAVAGE Search POLY+HISTIDINE+FUSION+TAG+CLEAVAGE
9 AFFINITY TAGS 86586 1% 30% 9 Search AFFINITY+TAGS Search AFFINITY+TAGS
10 SURFACE ENTROPY REDUCTION 80179 1% 50% 5 Search SURFACE+ENTROPY+REDUCTION Search SURFACE+ENTROPY+REDUCTION

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 COSTA, S , ALMEIDA, A , CASTRO, A , DOMINGUES, L , (2014) FUSION TAGS FOR PROTEIN SOLUBILITY, PURIFICATION, AND IMMUNOGENICITY IN ESCHERICHIA COLI: THE NOVEL FH8 SYSTEM.FRONTIERS IN MICROBIOLOGY. VOL. 5. ISSUE . P. - 75 42% 33
2 MALHOTRA, A , (2009) TAGGING FOR PROTEIN EXPRESSION.GUIDE TO PROTEIN PURIFICATION, SECOND EDITION. VOL. 463. ISSUE . P. 239 -258 48 58% 47
3 VINCENTELLI, R , CIMINO, A , GEERLOF, A , KUBO, A , SATOU, Y , CAMBILLAU, C , (2011) HIGH-THROUGHPUT PROTEIN EXPRESSION SCREENING AND PURIFICATION IN ESCHERICHIA COLI.METHODS. VOL. 55. ISSUE 1. P. 65 -72 32 70% 28
4 YADAV, DK , YADAV, N , YADAV, S , HAQUE, S , TUTEJA, N , (2016) AN INSIGHT INTO FUSION TECHNOLOGY AIDING EFFICIENT RECOMBINANT PROTEIN PRODUCTION FOR FUNCTIONAL PROTEOMICS.ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. VOL. 612. ISSUE . P. 57 -77 70 31% 0
5 YOUNG, CL , BRITTON, ZT , ROBINSON, AS , (2012) RECOMBINANT PROTEIN EXPRESSION AND PURIFICATION: A COMPREHENSIVE REVIEW OF AFFINITY TAGS AND MICROBIAL APPLICATIONS.BIOTECHNOLOGY JOURNAL. VOL. 7. ISSUE 5. P. 620 -634 55 31% 93
6 OHANA, RF , ENCELL, LP , ZHAO, K , SIMPSON, D , SLATER, MR , URH, M , WOOD, KV , (2009) HALOTAG7: A GENETICALLY ENGINEERED TAG THAT ENHANCES BACTERIAL EXPRESSION OF SOLUBLE PROTEINS AND IMPROVES PROTEIN PURIFICATION.PROTEIN EXPRESSION AND PURIFICATION. VOL. 68. ISSUE 1. P. 110-120 28 70% 52
7 COSTA, SJ , ALMEIDA, A , CASTRO, A , DOMINGUES, L , BESIR, H , (2013) THE NOVEL FH8 AND H FUSION PARTNERS FOR SOLUBLE PROTEIN EXPRESSION IN ESCHERICHIA COLI: A COMPARISON WITH THE TRADITIONAL GENE FUSION TECHNOLOGY.APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. VOL. 97. ISSUE 15. P. 6779-6791 23 74% 14
8 ESPOSITO, D , CHATTERJEE, DK , (2006) ENHANCEMENT OF SOLUBLE PROTEIN EXPRESSION THROUGH THE USE OF FUSION TAGS.CURRENT OPINION IN BIOTECHNOLOGY. VOL. 17. ISSUE 4. P. 353-358 27 56% 220
9 BIRD, LE , (2011) HIGH THROUGHPUT CONSTRUCTION AND SMALL SCALE EXPRESSION SCREENING OF MULTI-TAG VECTORS IN ESCHERICHIA COLI.METHODS. VOL. 55. ISSUE 1. P. 29 -37 26 65% 23
10 VINCENTELLI, R , ROMIER, C , (2016) COMPLEX RECONSTITUTION AND CHARACTERIZATION BY COMBINING CO-EXPRESSION TECHNIQUES IN ESCHERICHIA COLI WITH HIGH-THROUGHPUT.ADVANCED TECHNOLOGIES FOR PROTEIN COMPLEX PRODUCTION AND CHARACTERIZATION. VOL. 896. ISSUE . P. 43 -58 26 60% 0

Classes with closest relation at Level 1


Rank Class id link
1 26233 PLECTASIN//JIANGSU SUPERMOL MED MAT PLICAT//FUSION EXPRESSION
2 29611 ENTEROPEPTIDASE//DUODENASE//ENTEROKINASE
3 15795 AMPHIPOLS//UMR 7099//MEMBRANE PROTEIN
4 8183 INCLUSION BODIES//PROTEIN REFOLDING//REFOLDING
5 35810 BIFUNCTIONAL FUSION ENZYME//CELM2//END TO END FUSION
6 15110 IMMOBILIZED METAL AFFINITY CHROMATOGRAPHY//IMAC//IMMOBILIZED METAL ION AFFINITY CHROMATOGRAPHY
7 12753 T VECTOR//TA CLONING//GENE SYNTHESIS
8 12865 CELL FREE PROTEIN SYNTHESIS//CELL FREE EXPRESSION//CELL FREE
9 35565 MKIAA//ATAD3//ATAD3A
10 37492 UNIVERSAL STRESS PROTEIN//MJ0577//1JMV

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