Class information for:
Level 1: MEDULLARY THYROID CARCINOMA//RET PROTO ONCOGENE//MEDULLARY THYROID CANCER

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
1110 2847 33.2 76%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
6 4 GASTROENTEROLOGY & HEPATOLOGY//ONCOLOGY//SURGERY 1371034
139 3       THYROID//THYROID CANCER//GRAVES DISEASE 64904
301 2             THYROID CANCER//THYROID NODULE//PAPILLARY THYROID CARCINOMA 18583
1110 1                   MEDULLARY THYROID CARCINOMA//RET PROTO ONCOGENE//MEDULLARY THYROID CANCER 2847

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 MEDULLARY THYROID CARCINOMA authKW 3364865 16% 67% 466
2 RET PROTO ONCOGENE authKW 1499027 7% 72% 195
3 MEDULLARY THYROID CANCER authKW 914965 5% 59% 144
4 RET authKW 619132 7% 30% 190
5 MULTIPLE ENDOCRINE NEOPLASIA TYPE 2 authKW 483624 2% 72% 63
6 MEN 2A authKW 467048 2% 78% 56
7 MULTIPLE ENDOCRINE NEOPLASIA authKW 382369 4% 34% 106
8 C CELL HYPERPLASIA authKW 343140 1% 80% 40
9 RET MUTATION authKW 332755 1% 97% 32
10 CALCITONIN authKW 311456 7% 15% 199

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Endocrinology & Metabolism 12764 26% 0% 750
2 Oncology 4148 21% 0% 603
3 Pathology 2504 9% 0% 255
4 Surgery 1739 15% 0% 429
5 Genetics & Heredity 1085 9% 0% 268
6 Medicine, General & Internal 1003 10% 0% 290
7 Medical Laboratory Technology 555 3% 0% 73
8 Cell Biology 294 7% 0% 207
9 Radiology, Nuclear Medicine & Medical Imaging 231 5% 0% 136
10 Otorhinolaryngology 133 2% 0% 53

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 GEN VISCERAL VASC SURG 58139 2% 11% 51
2 CHARLIE HAYS CANC 42894 0% 100% 4
3 ONCOL UROL SURG 42894 0% 100% 4
4 PLA HOSP 117 42894 0% 100% 4
5 HIGH TECHNOL STUDY ENVIRONM DAMAGE ENDOCRINE 33396 0% 35% 9
6 MOL TRANSLAT ENDOCRINOL 31186 0% 36% 8
7 AMBISEN 28968 0% 27% 10
8 SECT ENDOCRINOL DIABETOL 25425 0% 22% 11
9 UMR 5641 24500 0% 29% 8
10 HUMAN CANC GENET GRP 22291 1% 13% 16

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 THYROID 26200 3% 3% 95
2 ENDOCRINE PATHOLOGY 13760 1% 4% 35
3 JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 9741 5% 1% 148
4 ENDOCRINE-RELATED CANCER 8348 1% 2% 36
5 SURGERY 6629 3% 1% 79
6 CLINICAL ENDOCRINOLOGY 6523 2% 1% 68
7 ANNALES D ENDOCRINOLOGIE 5992 1% 2% 34
8 ONCOGENE 4166 3% 0% 85
9 EUROPEAN JOURNAL OF ENDOCRINOLOGY 4126 2% 1% 45
10 JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION 3081 1% 1% 38

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 MEDULLARY THYROID CARCINOMA 3364865 16% 67% 466 Search MEDULLARY+THYROID+CARCINOMA Search MEDULLARY+THYROID+CARCINOMA
2 RET PROTO ONCOGENE 1499027 7% 72% 195 Search RET+PROTO+ONCOGENE Search RET+PROTO+ONCOGENE
3 MEDULLARY THYROID CANCER 914965 5% 59% 144 Search MEDULLARY+THYROID+CANCER Search MEDULLARY+THYROID+CANCER
4 RET 619132 7% 30% 190 Search RET Search RET
5 MULTIPLE ENDOCRINE NEOPLASIA TYPE 2 483624 2% 72% 63 Search MULTIPLE+ENDOCRINE+NEOPLASIA+TYPE+2 Search MULTIPLE+ENDOCRINE+NEOPLASIA+TYPE+2
6 MEN 2A 467048 2% 78% 56 Search MEN+2A Search MEN+2A
7 MULTIPLE ENDOCRINE NEOPLASIA 382369 4% 34% 106 Search MULTIPLE+ENDOCRINE+NEOPLASIA Search MULTIPLE+ENDOCRINE+NEOPLASIA
8 C CELL HYPERPLASIA 343140 1% 80% 40 Search C+CELL+HYPERPLASIA Search C+CELL+HYPERPLASIA
9 RET MUTATION 332755 1% 97% 32 Search RET+MUTATION Search RET+MUTATION
10 CALCITONIN 311456 7% 15% 199 Search CALCITONIN Search CALCITONIN

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 WELLS, SA , ASA, SL , DRALLE, H , ELISEI, R , EVANS, DB , GAGEL, RF , LEE, N , MACHENS, A , MOLEY, JF , PACINI, F , ET AL (2015) REVISED AMERICAN THYROID ASSOCIATION GUIDELINES FOR THE MANAGEMENT OF MEDULLARY THYROID CARCINOMA.THYROID. VOL. 25. ISSUE 6. P. 567 -610 226 74% 96
2 KLOOS, RT , ENG, C , EVANS, DB , FRANCIS, GL , GAGEL, RF , GHARIB, H , MOLEY, JF , PACINI, F , RINGEL, MD , SCHLUMBERGER, M , ET AL (2009) MEDULLARY THYROID CANCER: MANAGEMENT GUIDELINES OF THE AMERICAN THYROID ASSOCIATION.THYROID. VOL. 19. ISSUE 6. P. 565 -612 246 75% 474
3 WELLS, SA , PACINI, F , ROBINSON, BG , SANTORO, M , (2013) MULTIPLE ENDOCRINE NEOPLASIA TYPE 2 AND FAMILIAL MEDULLARY THYROID CARCINOMA: AN UPDATE.JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. VOL. 98. ISSUE 8. P. 3149 -3164 109 77% 62
4 MAIA, AL , SIQUEIRA, DR , KULCSAR, MAV , TINCANI, AJ , MAZETO, GMFS , MACIEL, LMZ , (2014) DIAGNOSIS, TREATMENT, AND FOLLOW-UP OF MEDULLARY THYROID CARCINOMA: RECOMMENDATIONS BY THE THYROID DEPARTMENT OF THE BRAZILIAN SOCIETY OF ENDOCRINOLOGY AND METABOLISM.ARQUIVOS BRASILEIROS DE ENDOCRINOLOGIA E METABOLOGIA. VOL. 58. ISSUE 7. P. 667 -700 159 68% 2
5 DE GROOT, JWB , LINKS, TP , PLUKKER, JTM , LIPS, CJM , HOFSTRA, RMW , (2006) RET AS A DIAGNOSTIC AND THERAPEUTIC TARGET IN SPORADIC AND HEREDITARY ENDOCRINE TUMORS.ENDOCRINE REVIEWS. VOL. 27. ISSUE 5. P. 535 -560 167 59% 156
6 MUKHERJEE, S , ZAKALIK, D , (2011) RET CODON 804 MUTATIONS IN MULTIPLE ENDOCRINE NEOPLASIA 2: GENOTYPE-PHENOTYPE CORRELATIONS AND IMPLICATIONS IN CLINICAL MANAGEMENT.CLINICAL GENETICS. VOL. 79. ISSUE 1. P. 1 -16 109 97% 9
7 FIGLIOLI, G , LANDI, S , ROMEI, C , ELISEI, R , GEMIGNANI, F , (2013) MEDULLARY THYROID CARCINOMA (MTC) AND RET PROTO-ONCOGENE: MUTATION SPECTRUM IN THE FAMILIAL CASES AND A META-ANALYSIS OF STUDIES ON THE SPORADIC FORM.MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH. VOL. 752. ISSUE 1. P. 36 -44 88 94% 22
8 SAKORAFAS, GH , FRIESS, H , PEROS, G , (2008) THE GENETIC BASIS OF HEREDITARY MEDULLARY THYROID CANCER: CLINICAL IMPLICATIONS FOR THE SURGEON, WITH A PARTICULAR EMPHASIS ON THE ROLE OF PROPHYLACTIC THYROIDECTOMY.ENDOCRINE-RELATED CANCER. VOL. 15. ISSUE 4. P. 871 -884 103 95% 20
9 ARIGHI, E , BORRELLO, MG , SARIOLA, H , (2005) RET TYROSINE KINASE SIGNALING IN DEVELOPMENT AND CANCER.CYTOKINE & GROWTH FACTOR REVIEWS. VOL. 16. ISSUE 4-5. P. 441-467 164 47% 187
10 MARGRAF, RL , CROCKETT, DK , KRAUTSCHEID, PMF , SEAMONS, R , CALDERON, FRO , WITTWER, CT , MAO, R , (2009) MULTIPLE ENDOCRINE NEOPLASIA TYPE 2 RET PROTOONCOGENE DATABASE: REPOSITORY OF MEN2-ASSOCIATED RET SEQUENCE VARIATION AND REFERENCE FOR GENOTYPE/PHENOTYPE CORRELATIONS.HUMAN MUTATION. VOL. 30. ISSUE 4. P. 548 -556 88 90% 38

Classes with closest relation at Level 1


Rank Class id link
1 13109 ANAPLASTIC THYROID CARCINOMA//ANAPLASTIC THYROID CANCER//LENVATINIB
2 18040 C CELLS//SEROTONIN BINDING PROTEINS//PARAFOLLICULAR CELLS
3 11097 ENTERIC NERVOUS SYSTEM//HIRSCHSPRUNGS DISEASE//HIRSCHSPRUNG DISEASE
4 8746 MENIN//MEN1//MULTIPLE ENDOCRINE NEOPLASIA TYPE 1
5 3413 PAPILLARY THYROID CARCINOMA//RET PTC//BRAFV600E MUTATION
6 24433 TC 99M V DMSA//BIOPHYS RADIOPHARMACEUT//PENTAVALENT TECHNETIUM 99M DIMERCAPTOSUCCINIC ACID
7 30013 ENDOCRINE SURG S//HASH1//CLIN SCI H4 750
8 17312 SOLID CELL NESTS//THYROID METASTASIS//THYROID METASTASES
9 25206 NONSPECIFIC STEROIDAL ESTERASE//V FES//TUMORICIDAL POTENTIAL
10 3831 GDNF//GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR//NEURTURIN

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