Class information for:
Level 1: COMT//CATECHOL O METHYLTRANSFERASE//COMT VAL158MET

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
10637 1046 52.7 85%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
11 4 NEUROSCIENCES//CLINICAL NEUROLOGY//NEUROL 1112395
76 3       NEUROSCIENCES//DOPAMINE//SEROTONIN 81359
446 2             AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS//5 HTTLPR//PSYCHIATRIC GENETICS 16189
10637 1                   COMT//CATECHOL O METHYLTRANSFERASE//COMT VAL158MET 1046

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 COMT authKW 3391675 28% 39% 296
2 CATECHOL O METHYLTRANSFERASE authKW 1939936 19% 33% 203
3 COMT VAL158MET authKW 480385 2% 69% 24
4 COMT GENE authKW 305077 2% 58% 18
5 CATECHOL O METHYLTRANSFERASE COMT authKW 258646 2% 37% 24
6 VAL158MET authKW 191057 1% 55% 12
7 COMT VAL158MET POLYMORPHISM authKW 182436 1% 63% 10
8 RS4680 authKW 169834 1% 73% 8
9 VAL158MET POLYMORPHISM authKW 168884 1% 64% 9
10 PSYCHIAT NEUROSCI GRP address 136206 1% 33% 14

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 Psychiatry 12891 40% 0% 419
2 Neurosciences 7597 50% 0% 518
3 Genetics & Heredity 1124 15% 0% 154
4 Behavioral Sciences 999 7% 0% 77
5 Neuroimaging 620 3% 0% 33
6 Psychology 542 5% 0% 57
7 Clinical Neurology 521 11% 0% 116
8 Pharmacology & Pharmacy 368 13% 0% 139
9 Psychology, Experimental 165 3% 0% 33
10 Psychology, Developmental 100 2% 0% 21

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PSYCHIAT NEUROSCI GRP 136206 1% 33% 14
2 GENES COGNIT PSYCHOSIS PROGRAM 111047 3% 14% 28
3 CLIN BRAIN DISORDERS BRANCH 89429 4% 7% 43
4 UNIT DYNAM IMAGING GENET 65678 0% 75% 3
5 SECT MENTAL DISORDERS 52120 0% 36% 5
6 SERV PSIQUIATRIA SERGAS 38920 0% 67% 2
7 PLICAT PSYCHOL 34744 0% 24% 5
8 AG GEDACHTNISSTORUNGEN PLASTIZITAT 29191 0% 100% 1
9 AGHIA SOPHIA CHILDREN HOSP 29191 0% 100% 1
10 ANTHROPOL UNITIBUBCIBERSAM 29191 0% 100% 1

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 PSYCHIATRIC GENETICS 39753 3% 4% 35
2 AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS 29426 4% 2% 43
3 GENES BRAIN AND BEHAVIOR 10833 2% 2% 20
4 MOLECULAR PSYCHIATRY 8638 2% 1% 26
5 BIOLOGICAL PSYCHIATRY 3685 3% 0% 34
6 NEUROPSYCHOPHARMACOLOGY 3280 2% 0% 24
7 PSYCHIATRY RESEARCH 3104 3% 0% 29
8 SCHIZOPHRENIA RESEARCH 1968 2% 0% 20
9 BEHAVIORAL AND BRAIN FUNCTIONS 1934 1% 1% 6
10 PHARMACOGENOMICS JOURNAL 1799 1% 1% 7

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 COMT 3391675 28% 39% 296 Search COMT Search COMT
2 CATECHOL O METHYLTRANSFERASE 1939936 19% 33% 203 Search CATECHOL+O+METHYLTRANSFERASE Search CATECHOL+O+METHYLTRANSFERASE
3 COMT VAL158MET 480385 2% 69% 24 Search COMT+VAL158MET Search COMT+VAL158MET
4 COMT GENE 305077 2% 58% 18 Search COMT+GENE Search COMT+GENE
5 CATECHOL O METHYLTRANSFERASE COMT 258646 2% 37% 24 Search CATECHOL+O+METHYLTRANSFERASE+COMT Search CATECHOL+O+METHYLTRANSFERASE+COMT
6 VAL158MET 191057 1% 55% 12 Search VAL158MET Search VAL158MET
7 COMT VAL158MET POLYMORPHISM 182436 1% 63% 10 Search COMT+VAL158MET+POLYMORPHISM Search COMT+VAL158MET+POLYMORPHISM
8 RS4680 169834 1% 73% 8 Search RS4680 Search RS4680
9 VAL158MET POLYMORPHISM 168884 1% 64% 9 Search VAL158MET+POLYMORPHISM Search VAL158MET+POLYMORPHISM
10 COMT POLYMORPHISM 93401 1% 40% 8 Search COMT+POLYMORPHISM Search COMT+POLYMORPHISM

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref.
in cl.		 Shr. of ref. in
cl.		 Citations
1 WITTE, AV , FLOEL, A , (2012) EFFECTS OF COMT POLYMORPHISMS ON BRAIN FUNCTION AND BEHAVIOR IN HEALTH AND DISEASE.BRAIN RESEARCH BULLETIN. VOL. 88. ISSUE 5. P. 418 -428 99 74% 52
2 COSTAS, J , SANJUAN, J , RAMOS-RIOS, R , PAZ, E , AGRA, S , IVORRA, JL , PARAMO, M , BRENLLA, J , ARROJO, M , (2011) HETEROZYGOSITY AT CATECHOL-O-METHYLTRANSFERASE VAL158MET AND SCHIZOPHRENIA: NEW DATA AND META-ANALYSIS.JOURNAL OF PSYCHIATRIC RESEARCH. VOL. 45. ISSUE 1. P. 7-14 66 73% 30
3 GONZALEZ-CASTRO, TB , HERNANDEZ-DIAZ, Y , JUAREZ-ROJOP, IE , LOPEZ-NARVAEZ, ML , TOVILLA-ZARATE, CA , FRESAN, A , (2016) THE ROLE OF A CATECHOL-O-METHYLTRANSFERASE (COMT) VAL158MET GENETIC POLYMORPHISM IN SCHIZOPHRENIA: A SYSTEMATIC REVIEW AND UPDATED META-ANALYSIS ON 32,816 SUBJECTS.NEUROMOLECULAR MEDICINE. VOL. 18. ISSUE 2. P. 216 -231 58 78% 0
4 TIAN, T , QIN, W , LIU, B , WANG, DW , WANG, JP , JIANG, TZ , YU, CS , (2013) CATECHOL-O-METHYLTRANSFERASE VAL158MET POLYMORPHISM MODULATES GRAY MATTER VOLUME AND FUNCTIONAL CONNECTIVITY OF THE DEFAULT MODE NETWORK.PLOS ONE. VOL. 8. ISSUE 10. P. - 64 71% 5
5 CRADDOCK, N , OWEN, MJ , O'DONOVAN, MC , (2006) THE CATECHOL-O-METHYL TRANSFERASE (COMT) GENE AS A CANDIDATE FOR PSYCHIATRIC PHENOTYPES: EVIDENCE AND LESSONS.MOLECULAR PSYCHIATRY. VOL. 11. ISSUE 5. P. 446 -458 61 60% 131
6 KLEIN, M , SCHMOEGER, M , KASPER, S , SCHOSSER, A , (2016) META-ANALYSIS OF THE COMT VAL158MET POLYMORPHISM IN MAJOR DEPRESSIVE DISORDER: THE ROLE OF GENDER.WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY. VOL. 17. ISSUE 2. P. 147 -158 60 55% 1
7 DICKINSON, D , ELVEVAG, B , (2009) GENES, COGNITION AND BRAIN THROUGH A COMT LENS.NEUROSCIENCE. VOL. 164. ISSUE 1. P. 72 -87 63 54% 91
8 IRA, E , ZANONI, M , RUGGERI, M , DAZZAN, P , TOSATO, S , (2013) COMT, NEUROPSYCHOLOGICAL FUNCTION AND BRAIN STRUCTURE IN SCHIZOPHRENIA: A SYSTEMATIC REVIEW AND NEUROBIOLOGICAL INTERPRETATION.JOURNAL OF PSYCHIATRY & NEUROSCIENCE. VOL. 38. ISSUE 6. P. 366-380 72 50% 6
9 TAMMIMAKI, AE , MANNISTO, PT , (2010) ARE GENETIC VARIANTS OF COMT ASSOCIATED WITH ADDICTION?.PHARMACOGENETICS AND GENOMICS. VOL. 20. ISSUE 12. P. 717 -741 72 49% 27
10 OKOCHI, T , IKEDA, M , KISHI, T , KAWASHIMA, K , KINOSHITA, Y , KITAJIMA, T , YAMANOUCHI, Y , TOMITA, M , INADA, T , OZAKI, N , ET AL (2009) META-ANALYSIS OF ASSOCIATION BETWEEN GENETIC VARIANTS IN COMT AND SCHIZOPHRENIA: AN UPDATE.SCHIZOPHRENIA RESEARCH. VOL. 110. ISSUE 1-3. P. 140 -148 46 71% 67

Classes with closest relation at Level 1


Rank Class id link
1 13868 ENTACAPONE//TOLCAPONE//COMT INHIBITORS
2 20072 MAOA//MONOAMINE OXIDASE A//MAOA GENE
3 16064 OPRM1//A118G//OPRM1 GENE
4 8933 DRD2//DRD4//D2 DOPAMINE RECEPTOR GENE
5 7759 DAT1//DOPAMINE TRANSPORTER GENE//ADHD
6 12212 DELAY PERIOD ACTIVITY//PREFRONTAL CORTEX//CORT CIRCUITS COMPUTAT
7 21057 CONTEXT PROCESSING//FUNCT IMAGING SECT PSYCHIAT//SALIENCE ATTRIBUTION TEST
8 3903 5 HTTLPR//SEROTONIN TRANSPORTER//SEROTONIN TRANSPORTER GENE
9 12432 DRD3//TARDIVE DYSKINESIA//HTR2A
10 14933 CYP1B1//CYP2S1//CYP2W1

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