Class information for:
Level 1: SOLID DISPERSION//SOLID DISPERSIONS//HOT MELT EXTRUSION

Basic class information
Class id #P Avg. number of
references		 Database coverage
of references
1023 2897 32.9 70%


Bar chart of Publication_year

Last years might be incomplete

Hierarchy of classes
The table includes all classes above and classes immediately below the current class.


Cluster id Level Cluster label #P
12 4 POLYMER SCIENCE//MATERIALS SCIENCE, PAPER & WOOD//CHEMISTRY, PHYSICAL 1084170
41 3       INTERNATIONAL JOURNAL OF PHARMACEUTICS//DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY//PHARMACOLOGY & PHARMACY 99449
157 2             DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY//SOLID DISPERSION//INTERNATIONAL JOURNAL OF PHARMACEUTICS 22895
1023 1                   SOLID DISPERSION//SOLID DISPERSIONS//HOT MELT EXTRUSION 2897

Terms with highest relevance score


rank Term termType Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 SOLID DISPERSION authKW 5921594 26% 74% 763
2 SOLID DISPERSIONS authKW 1768382 8% 75% 224
3 HOT MELT EXTRUSION authKW 1451933 7% 67% 205
4 AMORPHOUS SOLID DISPERSION authKW 1182750 4% 91% 124
5 AMORPHOUS authKW 539852 14% 13% 404
6 IND PHYS PHARM address 332895 5% 22% 144
7 DISSOLUTION authKW 307290 13% 8% 382
8 CO AMORPHOUS authKW 305616 1% 100% 29
9 DISSOLUTION ENHANCEMENT authKW 305134 2% 55% 53
10 PHYSICAL STABILITY authKW 275234 4% 23% 112

Web of Science journal categories


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with term
in class
1 Pharmacology & Pharmacy 62540 84% 0% 2420
2 Chemistry, Medicinal 22232 26% 0% 759
3 Chemistry, Multidisciplinary 3562 25% 0% 710
4 Medicine, Research & Experimental 506 6% 0% 176
5 Thermodynamics 211 3% 0% 81
6 Chemistry, Analytical 49 3% 0% 98
7 Engineering, Chemical 48 3% 0% 94
8 Crystallography 43 2% 0% 50
9 Materials Science, Biomaterials 34 1% 0% 24
10 Polymer Science 29 2% 0% 72

Address terms


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 IND PHYS PHARM 332895 5% 22% 144
2 FARMACOTECHNOL BIOFARM 160640 1% 42% 36
3 PII PHARMACEUT TECHNOL 159381 1% 69% 22
4 PHARMACEUT TECHNOL FORMULAT 86424 1% 37% 22
5 PHARMACOTECHNOL BIOPHARM 70774 1% 20% 34
6 DRUG DELIVERY BIOMAT GRP 58538 0% 56% 10
7 GLOBAL DEV TECH MKT 54196 0% 86% 6
8 PHARMACEUT 52572 13% 1% 384
9 PHARMACEUT DRUG DELIVERY 52291 1% 21% 24
10 BIOAVAI IL CONTROL 50361 0% 34% 14

Journals


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class
1 INTERNATIONAL JOURNAL OF PHARMACEUTICS 145365 16% 3% 467
2 DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY 143612 9% 5% 271
3 MOLECULAR PHARMACEUTICS 88834 6% 5% 163
4 EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS 74521 6% 4% 162
5 JOURNAL OF PHARMACEUTICAL SCIENCES 72629 10% 2% 278
6 AAPS PHARMSCITECH 57367 3% 5% 100
7 PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY 30523 2% 5% 63
8 EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES 27500 3% 3% 96
9 PHARMACEUTICAL RESEARCH 24236 5% 2% 136
10 JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY 12503 1% 3% 35

Author Key Words


Rank Term Chi square Shr. of publ. in
class containing
term		 Class's shr. of
term's tot. occurrences		 #P with
term in
class		 LCSH search Wikipedia search
1 SOLID DISPERSION 5921594 26% 74% 763 Search SOLID+DISPERSION Search SOLID+DISPERSION
2 SOLID DISPERSIONS 1768382 8% 75% 224 Search SOLID+DISPERSIONS Search SOLID+DISPERSIONS
3 HOT MELT EXTRUSION 1451933 7% 67% 205 Search HOT+MELT+EXTRUSION Search HOT+MELT+EXTRUSION
4 AMORPHOUS SOLID DISPERSION 1182750 4% 91% 124 Search AMORPHOUS+SOLID+DISPERSION Search AMORPHOUS+SOLID+DISPERSION
5 AMORPHOUS 539852 14% 13% 404 Search AMORPHOUS Search AMORPHOUS
6 DISSOLUTION 307290 13% 8% 382 Search DISSOLUTION Search DISSOLUTION
7 CO AMORPHOUS 305616 1% 100% 29 Search CO+AMORPHOUS Search CO+AMORPHOUS
8 DISSOLUTION ENHANCEMENT 305134 2% 55% 53 Search DISSOLUTION+ENHANCEMENT Search DISSOLUTION+ENHANCEMENT
9 PHYSICAL STABILITY 275234 4% 23% 112 Search PHYSICAL+STABILITY Search PHYSICAL+STABILITY
10 SUPERSATURATION 232817 5% 17% 134 Search SUPERSATURATION Search SUPERSATURATION

Core articles
The table includes core articles in the class. The following variables is taken into account for the relevance score of an article in a cluster c:
(1) Number of references referring to publications in the class.
(2) Share of total number of active references referring to publications in the class.
(3) Age of the article. New articles get higher score than old articles.
(4) Citation rate, normalized to year.


Rank Reference # ref. in
cl.		 Shr. of ref. in
cl.		 Citations
1 BAGHEL, S , CATHCART, H , O'REILLY, NJ , (2016) POLYMERIC AMORPHOUS SOLID DISPERSIONS: A REVIEW OF AMORPHIZATION, CRYSTALLIZATION, STABILIZATION, SOLID-STATE CHARACTERIZATION, AND AQUEOUS SOLUBILIZATION OF BIOPHARMACEUTICAL CLASSIFICATION SYSTEM CLASS II DRUGS.JOURNAL OF PHARMACEUTICAL SCIENCES. VOL. 105. ISSUE 9. P. 2527 -2544 134 78% 7
2 PAUDEL, A , WORKU, ZA , GUNS, JMS , GUNS, S , VAN DEN MOOTER, G , (2013) MANUFACTURING OF SOLID DISPERSIONS OF POORLY WATER SOLUBLE DRUGS BY SPRAY DRYING: FORMULATION AND PROCESS CONSIDERATIONS.INTERNATIONAL JOURNAL OF PHARMACEUTICS. VOL. 453. ISSUE 1. P. 253 -284 136 62% 92
3 LI, YC , PANG, HS , GUO, ZF , LIN, L , DONG, YX , LI, G , LU, M , WU, CB , (2014) INTERACTIONS BETWEEN DRUGS AND POLYMERS INFLUENCING HOT MELT EXTRUSION.JOURNAL OF PHARMACY AND PHARMACOLOGY. VOL. 66. ISSUE 2. P. 148-166 112 85% 11
4 VO, CLN , PARK, C , LEE, BJ , (2013) CURRENT TRENDS AND FUTURE PERSPECTIVES OF SOLID DISPERSIONS CONTAINING POORLY WATER-SOLUBLE DRUGS.EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS. VOL. 85. ISSUE 3. P. 799-813 96 74% 93
5 SINGH, A , VAN DEN MOOTER, G , (2016) SPRAY DRYING FORMULATION OF AMORPHOUS SOLID DISPERSIONS.ADVANCED DRUG DELIVERY REVIEWS. VOL. 100. ISSUE . P. 27 -50 116 59% 6
6 LU, M , GUO, ZF , LI, YC , PANG, HS , LIN, L , LIU, X , PAN, X , WU, CB , (2014) APPLICATION OF HOT MELT EXTRUSION FOR POORLY WATER-SOLUBLE DRUGS: LIMITATIONS, ADVANCES AND FUTURE PROSPECTS.CURRENT PHARMACEUTICAL DESIGN. VOL. 20. ISSUE 3. P. 369 -387 116 80% 6
7 VASCONCELOS, T , MARQUES, S , DAS NEVES, J , SARMENTO, B , (2016) AMORPHOUS SOLID DISPERSIONS: RATIONAL SELECTION OF A MANUFACTURING PROCESS.ADVANCED DRUG DELIVERY REVIEWS. VOL. 100. ISSUE . P. 85 -101 97 67% 6
8 SHAH, S , MADDINENI, S , LU, JN , REPKA, MA , (2013) MELT EXTRUSION WITH POORLY SOLUBLE DRUGS.INTERNATIONAL JOURNAL OF PHARMACEUTICS. VOL. 453. ISSUE 1. P. 233 -252 105 71% 54
9 MENG, F , GALA, U , CHAUHAN, H , (2015) CLASSIFICATION OF SOLID DISPERSIONS: CORRELATION TO (I) STABILITY AND SOLUBILITY (II) PREPARATION AND CHARACTERIZATION TECHNIQUES.DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY. VOL. 41. ISSUE 9. P. 1401 -1415 103 83% 2
10 ALI, R , AL-JENOOBI, FI , AL-MOHIZEA, AM , ALAM, MA , (2012) SOLID DISPERSIONS: A STRATEGY FOR POORLY AQUEOUS SOLUBLE DRUGS AND TECHNOLOGY UPDATES.EXPERT OPINION ON DRUG DELIVERY. VOL. 9. ISSUE 11. P. 1419 -1440 92 88% 36

Classes with closest relation at Level 1


Rank Class id link
1 33826 LIQUISOLID COMPACTS//LIQUISOLID TABLETS//LIQUISOLID
2 10143 NANOSUSPENSION//ANTISOLVENT PRECIPITATION//DRUG NANOPARTICLES
3 24183 ISOTHERMAL MICROCALORIMETRY//AMORPHOUS CONTENT//SORPTION CALORIMETRY
4 22082 SPRAY CONGEALING//SOLID LIPID EXTRUSION//LIPID IMPLANTS
5 34022 DRUG PRINTING//SULPHOALUMINATE MDF CEMENT//THERMAL INK JET
6 4374 POLYMORPH//HYDRATE//PSEUDOPOLYMORPHISM
7 6445 SELF EMULSIFYING DRUG DELIVERY SYSTEM//SELF MICROEMULSIFYING DRUG DELIVERY SYSTEM//SMEDDS
8 24435 SPHERICAL CRYSTALLIZATION//CRYSTALLO CO AGGLOMERATION//SPHERICAL AGGLOMERATION
9 29091 NANOMAT MICROSYST GRP//GLASSY ANOMALIES//GRP NANOMATS MICROSYST
10 855 INCLUSION COMPLEX//CYCLODEXTRIN//HYDROXYPROPYL BETA CYCLODEXTRIN

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