Class information for:
Level 3: NOONAN SYNDROME//COSTELLO SYNDROME//PROTEIN TYROSINE PHOSPHATASE

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
630 9614 41.1 83%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 4)


ID, lev.
above		 Publications Label for level above
0 3633673 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//MED

Classes in level below (level 2)


ID, lev.
below		 Publications Label for level below
2255 4236 PTP1B//PROTEIN TYROSINE PHOSPHATASE//PRL 3
2325 4032 NOONAN SYNDROME//COSTELLO SYNDROME//THROMBOSPONDIN 1
3304 1346 SPARC//GROWTH DIFFERENTIATION FACTOR 15//GDF 15

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 NOONAN SYNDROME Author keyword 474 78% 3% 314
2 COSTELLO SYNDROME Author keyword 271 88% 1% 127
3 PROTEIN TYROSINE PHOSPHATASE Author keyword 182 41% 4% 345
4 THROMBOSPONDIN 1 Author keyword 174 55% 2% 219
5 SPARC Author keyword 173 55% 2% 216
6 PTPN11 Author keyword 152 76% 1% 107
7 THROMBOSPONDIN Author keyword 138 49% 2% 204
8 PTP1B Author keyword 135 59% 2% 153
9 PRL 3 Author keyword 116 88% 1% 56
10 SHP 2 Author keyword 115 50% 2% 166

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 NOONAN SYNDROME 474 78% 3% 314 Search NOONAN+SYNDROME Search NOONAN+SYNDROME
2 COSTELLO SYNDROME 271 88% 1% 127 Search COSTELLO+SYNDROME Search COSTELLO+SYNDROME
3 PROTEIN TYROSINE PHOSPHATASE 182 41% 4% 345 Search PROTEIN+TYROSINE+PHOSPHATASE Search PROTEIN+TYROSINE+PHOSPHATASE
4 THROMBOSPONDIN 1 174 55% 2% 219 Search THROMBOSPONDIN+1 Search THROMBOSPONDIN+1
5 SPARC 173 55% 2% 216 Search SPARC Search SPARC
6 PTPN11 152 76% 1% 107 Search PTPN11 Search PTPN11
7 THROMBOSPONDIN 138 49% 2% 204 Search THROMBOSPONDIN Search THROMBOSPONDIN
8 PTP1B 135 59% 2% 153 Search PTP1B Search PTP1B
9 PRL 3 116 88% 1% 56 Search PRL+3 Search PRL+3
10 SHP 2 115 50% 2% 166 Search SHP+2 Search SHP+2

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 INTEGRIN ASSOCIATED PROTEIN 268 67% 3% 245
2 PTPN11 MUTATIONS 199 81% 1% 121
3 PLATELET THROMBOSPONDIN 188 76% 1% 132
4 PROTEIN TYROSINE PHOSPHATASE 147 21% 6% 618
5 SH2 CONTAINING PHOSPHOTYROSINE PHOSPHATASE 136 64% 1% 133
6 NOONAN SYNDROME 129 43% 2% 231
7 FACIO CUTANEOUS SYNDROME 124 60% 1% 134
8 SECRETE THROMBOSPONDIN 123 91% 1% 51
9 MIC 1 122 88% 1% 58
10 MACROPHAGE INHIBITORY CYTOKINE 1 118 65% 1% 112

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
The Interaction Between Signal Regulatory Protein Alpha (SIRP alpha) and CD47: Structure, Function, and Therapeutic Target 2014 18 148 74%
Inside the human cancer tyrosine phosphatome 2011 133 182 64%
PTP1B as a drug target: recent developments in PTP1B inhibitor discovery 2007 238 69 90%
The 'Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling 2003 596 92 67%
Protein tyrosine phosphatases: from genes, to function, to disease 2006 618 126 44%
Noonan Syndrome: Clinical Features, Diagnosis, and Management Guidelines 2010 91 110 95%
The RASopathies 2013 47 63 57%
Protein tyrosine phosphatases in the human genome 2004 929 69 32%
Protein-tyrosine phosphatases and cancer 2006 283 154 72%
The RASopathies: developmental syndromes of Ras/MAPK pathway dysregulation 2009 206 49 47%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 BIOSIGNAL SCI 75 83% 0.4% 43
2 BARBARA JANE LEVY MOL NEUROONCOL 15 71% 0.1% 12
3 SPECIAL HEMATOL 14 51% 0.2% 20
4 HOPE HEART PROGRAM 14 32% 0.4% 37
5 BIOPATHOL IMAGING DIAGNOST 13 39% 0.3% 27
6 SECT HISTOL CELL BIOL 11 38% 0.2% 23
7 EDMOND H FI ER SIGNAL TRANSDUCT 11 40% 0.2% 21
8 CHEM GENOM CORE IL 10 57% 0.1% 12
9 BIOPATHOL HUMAN POPULAT ENVIRONM PATHOL 9 67% 0.1% 8
10 DIPARTIMENTO BIOL CELLULARE NEUROSCI 8 24% 0.3% 28

Related classes at same level (level 3)


Rank Relatedness score Related classes
1 0.0000004729 HER 2//TRASTUZUMAB//CHRONIC MYELOID LEUKEMIA
2 0.0000002789 CD44//HYALURONAN//INTEGRIN
3 0.0000002550 HEPARANASE//MIDKINE//HEPARAN SULFATE
4 0.0000002471 TRANSCRIPTION FACTOR//ETS 1//C JUN
5 0.0000002344 HYPOPHOSPHATASIA//ALKALINE PHOSPHATASE//TISSUE NONSPECIFIC ALKALINE PHOSPHATASE
6 0.0000002124 PROSTATE CANCER//PROSTATIC NEOPLASMS//RADICAL PROSTATECTOMY
7 0.0000001979 POMPE DISEASE//PROTEIN KINASE CK2//GLYCOGEN STORAGE DISEASE TYPE II
8 0.0000001904 OPHTHALMOLOGY//RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES//OPHTHALMOL
9 0.0000001765 EXPERIMENTAL HEMATOLOGY//THROMBOPOIETIN//JOURNAL OF INTERFERON RESEARCH
10 0.0000001686 DEVELOPMENTAL BIOLOGY//DEVELOPMENT//DROSOPHILA