Class information for:
Level 3: DIHYDROPYRIMIDINE DEHYDROGENASE//5 FLUOROURACIL//THYMIDINE PHOSPHORYLASE

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
499 19953 32.5 70%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 4)


ID, lev.
above		 Publications Label for level above
0 3633673 BIOCHEMISTRY & MOLECULAR BIOLOGY//CELL BIOLOGY//MED

Classes in level below (level 2)


ID, lev.
below		 Publications Label for level below
903 10618 DIHYDROPYRIMIDINE DEHYDROGENASE//5 FLUOROURACIL//THYMIDINE PHOSPHORYLASE
2118 4652 BINUCLEATED LYMPHOCYTES//HUMANIZED MICE//CHEMOSENSITIVITY TEST
2795 2580 CAMPTOTHECIN//SN 38//TOPOTECAN
2999 2103 CHEMOTHERAPY INDUCED PERIPHERAL NEUROPATHY//VINFLUNINE//VINCRISTINE

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of publ.
in class
1 DIHYDROPYRIMIDINE DEHYDROGENASE Author keyword 554 84% 1% 298
2 5 FLUOROURACIL Author keyword 531 33% 7% 1349
3 THYMIDINE PHOSPHORYLASE Author keyword 494 74% 2% 368
4 IRINOTECAN Author keyword 354 39% 4% 718
5 S 1 Author keyword 332 55% 2% 412
6 OXALIPLATIN Author keyword 292 34% 3% 693
7 THYMIDYLATE SYNTHASE Author keyword 289 48% 2% 443
8 CAMPTOTHECIN Author keyword 236 40% 2% 466
9 LEUCOVORIN Author keyword 228 54% 1% 291
10 CAPECITABINE Author keyword 226 36% 3% 505

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of publ.
in class		 LCSH search Wikipedia search
1 DIHYDROPYRIMIDINE DEHYDROGENASE 554 84% 1% 298 Search DIHYDROPYRIMIDINE+DEHYDROGENASE Search DIHYDROPYRIMIDINE+DEHYDROGENASE
2 5 FLUOROURACIL 531 33% 7% 1349 Search 5+FLUOROURACIL Search 5+FLUOROURACIL
3 THYMIDINE PHOSPHORYLASE 494 74% 2% 368 Search THYMIDINE+PHOSPHORYLASE Search THYMIDINE+PHOSPHORYLASE
4 IRINOTECAN 354 39% 4% 718 Search IRINOTECAN Search IRINOTECAN
5 S 1 332 55% 2% 412 Search S+1 Search S+1
6 OXALIPLATIN 292 34% 3% 693 Search OXALIPLATIN Search OXALIPLATIN
7 THYMIDYLATE SYNTHASE 289 48% 2% 443 Search THYMIDYLATE+SYNTHASE Search THYMIDYLATE+SYNTHASE
8 CAMPTOTHECIN 236 40% 2% 466 Search CAMPTOTHECIN Search CAMPTOTHECIN
9 LEUCOVORIN 228 54% 1% 291 Search LEUCOVORIN Search LEUCOVORIN
10 CAPECITABINE 226 36% 3% 505 Search CAPECITABINE Search CAPECITABINE

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of publ.
in class
1 FLUOROURACIL 868 30% 12% 2404
2 5 FLUOROURACIL 664 27% 11% 2121
3 FOLINIC ACID 471 47% 4% 741
4 LEUCOVORIN 456 33% 6% 1123
5 DIHYDROPYRIMIDINE DEHYDROGENASE 402 60% 2% 434
6 BIOCHEMICAL MODULATION 365 76% 1% 258
7 HIGH DOSE LEUCOVORIN 319 58% 2% 369
8 CPT 11 297 50% 2% 432
9 5 DEOXY 5 FLUOROURIDINE 263 80% 1% 165
10 ADVANCED COLORECTAL CANCER 259 40% 3% 510

Journals


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 CANCER CHEMOTHERAPY AND PHARMACOLOGY 82 11% 4% 734
2 CLINICAL COLORECTAL CANCER 16 20% 0% 75
3 GASTRIC CANCER 15 16% 0% 85
4 GI CANCER 2 13% 0% 13

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
5-Fluorouracil: Mechanisms of action and clinical strategies 2003 1149 96 70%
A Review of the Evolution of Systemic Chemotherapy in the Management of Colorectal Cancer 2015 3 61 69%
Humanized mice for immune system investigation: progress, promise and challenges 2012 112 123 65%
Patient-derived tumour xenografts as models for oncology drug development 2012 142 106 46%
Chemotherapy-induced peripheral neuropathy: What do we know about mechanisms? 2015 4 187 47%
Chemotherapy-induced neuropathy: A comprehensive survey 2014 22 99 66%
Humanized mice in translational biomedical research 2007 460 125 35%
Basic science and clinical management of painful and non-painful chemotherapy-related neuropathy 2015 3 80 46%
Clinical pharmacokinetics and metabolism of irinotecan (CPT-11) 2001 339 132 70%
Chemotherapy-induced peripheral neuropathy: Prevention and treatment strategies 2008 165 52 73%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 PATHOGEN BIOCHEM MED 41 100% 0.1% 15
2 CANC 2 19 74% 0.1% 14
3 UNIT NEUROONCOL 16 61% 0.1% 17
4 GASTROINTESTINAL ONCOL 15 13% 0.5% 105
5 GERCOR 15 77% 0.1% 10
6 STEHLIN FDN CANC 13 69% 0.1% 11
7 EPIDEMIOL CLIN INFORMAT MANAGEMENT 11 38% 0.1% 23
8 DANIEL DEN HOED KLIN 11 28% 0.2% 33
9 TOKUSHIMA 11 18% 0.3% 53
10 ONCOPHARMACOL 10 22% 0.2% 38

Related classes at same level (level 3)


Rank Relatedness score Related classes
1 0.0000004278 NM23//RIBONUCLEOTIDE REDUCTASE//DEOXYCYTIDINE KINASE
2 0.0000003895 COLONOSCOPY//BARRETTS ESOPHAGUS//ESOPHAGEAL CANCER
3 0.0000003150 NON SMALL CELL LUNG CANCER//BRAIN METASTASES//LUNG CANCER
4 0.0000002626 SOLID LIPID NANOPARTICLES//L ASPARAGINASE//NANOSTRUCTURED LIPID CARRIERS
5 0.0000002257 KERNICTERUS//HYPERBILIRUBINEMIA//BILIRUBIN
6 0.0000002142 RECTAL CANCER//INCISIONAL HERNIA//TOTAL MESORECTAL EXCISION
7 0.0000002055 P GLYCOPROTEIN//MULTIDRUG RESISTANCE//SGLT2 INHIBITOR
8 0.0000001972 BREAST CANCER//BREAST//BRCA1
9 0.0000001936 HOMOCYSTEINE//FOLATE//FOLIC ACID
10 0.0000001919 CYTOMETRY//ANALYTICAL AND QUANTITATIVE CYTOLOGY AND HISTOLOGY//CYTOMETRY PART A