Class information for:
Level 2: CONGENITAL ADRENAL HYPERPLASIA//21 HYDROXYLASE DEFICIENCY//CYP21A2

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
928 10457 35.2 64%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 3)


ID, lev.
above		 Publications Label for level above
252 41951 PHEOCHROMOCYTOMA//NEUROBLASTOMA//ALDOSTERONE

Classes in level below (level 1)


ID, lev. below Publications Label for level below
2723 2088 CONGENITAL ADRENAL HYPERPLASIA//21 HYDROXYLASE DEFICIENCY//CYP21A2
6247 1444 ALDOSTERONE BIOSYNTHESIS//ALDOSTERONE SYNTHASE DEFICIENCY//ALDOSTERONE SYNTHESIS
7744 1254 ADRENAL HYPOPLASIA CONGENITA//DAX 1//STEROIDOGENIC FACTOR 1
10195 1020 PNEUMADIN//ADRENAL INNERVATION//LIPID CYTOPLASM RATIO
11363 920 STEROIDOGENIC ACUTE REGULATORY PROTEIN//STARD6//STEROIDOGENIC ACUTE REGULATORY PROTEIN STAR
12270 854 17 ALPHA HYDROXYLASE 17 20 LYASE DEFICIENCY//17 ALPHA HYDROXYLASE DEFICIENCY//ADRENARCHE
15815 621 ADRENODOXIN//CYTOCHROME P450SCC//ADRENODOXIN REDUCTASE
17013 558 STUDIES REPROD//MED STUDIES REPROD PHYSIOL//FETAL ZONE
20973 377 19 NORDEOXYCORTICOSTERONE//ADRENAL RENAL PORTAL CIRCULATION//19 NORALDOSTERONE
21241 367 C 19 STEROIDS//CYP2D16//EMI105
22192 333 MRC MOLEC ENDOCRINOL GRP//3 BETA HYDROXYSTEROID DEHYDROGENASE//HSD3B2 GENE
25597 229 SKIN ONTOGENY//LIVER GROWTH//4 APP
25976 219 Y 1 ADRENAL CELLS//DOMESTIC MALLARD//ADRENAL CHOLESTEROL
28186 173 ADLAY BRAN//ZONA FASCICULATA RETICULARIS CELLS//ADLAY SEED

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 CONGENITAL ADRENAL HYPERPLASIA Author keyword 537 64% 5% 523
2 21 HYDROXYLASE DEFICIENCY Author keyword 335 82% 2% 194
3 CYP21A2 Author keyword 122 86% 1% 62
4 ENDOCRINE RESEARCH Journal 84 24% 3% 309
5 DAX 1 Author keyword 76 81% 0% 46
6 ADRENAL CORTEX Author keyword 73 30% 2% 209
7 ADRENODOXIN Author keyword 64 64% 1% 63
8 STEROIDOGENESIS Author keyword 64 18% 3% 317
9 11 BETA HYDROXYLASE DEFICIENCY Author keyword 62 90% 0% 27
10 ADRENAL HYPOPLASIA CONGENITA Author keyword 60 83% 0% 34

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 CONGENITAL ADRENAL HYPERPLASIA 537 64% 5% 523 Search CONGENITAL+ADRENAL+HYPERPLASIA Search CONGENITAL+ADRENAL+HYPERPLASIA
2 21 HYDROXYLASE DEFICIENCY 335 82% 2% 194 Search 21+HYDROXYLASE+DEFICIENCY Search 21+HYDROXYLASE+DEFICIENCY
3 CYP21A2 122 86% 1% 62 Search CYP21A2 Search CYP21A2
4 DAX 1 76 81% 0% 46 Search DAX+1 Search DAX+1
5 ADRENAL CORTEX 73 30% 2% 209 Search ADRENAL+CORTEX Search ADRENAL+CORTEX
6 ADRENODOXIN 64 64% 1% 63 Search ADRENODOXIN Search ADRENODOXIN
7 STEROIDOGENESIS 64 18% 3% 317 Search STEROIDOGENESIS Search STEROIDOGENESIS
8 11 BETA HYDROXYLASE DEFICIENCY 62 90% 0% 27 Search 11+BETA+HYDROXYLASE+DEFICIENCY Search 11+BETA+HYDROXYLASE+DEFICIENCY
9 ADRENAL HYPOPLASIA CONGENITA 60 83% 0% 34 Search ADRENAL+HYPOPLASIA+CONGENITA Search ADRENAL+HYPOPLASIA+CONGENITA
10 STEROIDOGENIC ACUTE REGULATORY PROTEIN 60 54% 1% 77 Search STEROIDOGENIC+ACUTE+REGULATORY+PROTEIN Search STEROIDOGENIC+ACUTE+REGULATORY+PROTEIN

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 STEROID 21 HYDROXYLASE DEFICIENCY 338 76% 2% 236
2 SIDE CHAIN CLEAVAGE 249 45% 4% 421
3 21 HYDROXYLASE DEFICIENCY 243 46% 4% 393
4 CONGENITAL ADRENAL HYPERPLASIA 228 31% 6% 615
5 LIPOID ADRENAL HYPERPLASIA 185 77% 1% 125
6 DISEASE MANIFESTATION 154 92% 1% 60
7 STEROIDOGENIC FACTOR I 147 36% 3% 324
8 CYP21 134 86% 1% 68
9 ACUTE REGULATORY PROTEIN 134 32% 3% 343
10 MOLECULAR GENOTYPE 114 93% 0% 42

Journals


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 ENDOCRINE RESEARCH 84 24% 3% 309

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
The Molecular Biology, Biochemistry, and Physiology of Human Steroidogenesis and Its Disorders 2011 237 664 53%
Regulation of the adrenocortical stem cell niche: implications for disease 2015 6 162 48%
Congenital adrenal hyperplasia due to 21-hydroxylase deficiency 2000 566 475 67%
Congenital adrenal hyperplasia 2003 329 80 81%
StAR protein and the regulation of steroid hormone biosynthesis 2001 383 143 80%
Acute and chronic regulation of aldosterone production 2012 49 154 73%
Regulation of the acute production of steroids in steroidogenic cells 1996 626 186 52%
Minireview: Steroidogenic Factor 1: Its Roles in Differentiation, Development, and Disease 2010 83 170 72%
Congenital adrenal hyperplasia 2005 242 124 73%
Premature adrenarche: Etiology, clinical findings, and consequences 2015 2 120 68%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 STUDIES REPROD 14 41% 0.2% 26
2 ADRENAL STEROID DISORDERS PROGRAM 13 69% 0.1% 11
3 HLTH SCI SW MED BIOCHEM 11 49% 0.2% 17
4 REPROD ENDOCRINOL SIGNALING GRP 11 69% 0.1% 9
5 REPROD DEV SCI CLIN BIOCHEM 9 64% 0.1% 9
6 MRC MOLEC ENDOCRINOL GRP 8 70% 0.1% 7
7 MED STUDIES REPROD PHYSIOL 8 75% 0.1% 6
8 HLTH SCI BIOCHEM CELL BIOL 6 80% 0.0% 4
9 EA 3739 6 71% 0.0% 5
10 STUDIES REPRODB SLER S 11 019 6 71% 0.0% 5

Related classes at same level (level 2)


Rank Relatedness score Related classes
1 0.0000011501 NUR77//NURR1//TR4
2 0.0000011226 11 BETA HYDROXYSTEROID DEHYDROGENASE//ALDOSTERONE//EPLERENONE
3 0.0000009605 POLYCYSTIC OVARY SYNDROME//PCOS//HYPERANDROGENISM
4 0.0000009171 TESTIS//SERTOLI CELLS//SPERMATOGENESIS
5 0.0000008319 PHEOCHROMOCYTOMA//NEUROBLASTOMA//PRIMARY ALDOSTERONISM
6 0.0000008132 ALDOSE REDUCTASE//ALDO KETO REDUCTASE//17 BETA HYDROXYSTEROID DEHYDROGENASE
7 0.0000007950 PERIPHERAL BENZODIAZEPINE RECEPTORS//TSPO//DIAZEPAM BINDING INHIBITOR
8 0.0000007914 DOPING CONTROL//EPITESTOSTERONE//DOPING ANALYSIS
9 0.0000007682 APECED//AIRE//ADRENAL INSUFFICIENCY
10 0.0000007555 JOURNAL OF DEVELOPMENTAL PHYSIOLOGY//INTRAMEMBRANOUS ABSORPTION//FETAL SHEEP