Class information for:
Level 2: PTEN//MTOR//LHERMITTE DUCLOS DISEASE

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
625 13166 47.2 91%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 3)


ID, lev.
above		 Publications Label for level above
100 72119 HER 2//TRASTUZUMAB//CHRONIC MYELOID LEUKEMIA

Classes in level below (level 1)


ID, lev. below Publications Label for level below
1139 2730 MTOR//RAPAMYCIN//CCI 779
2886 2047 P110 ALPHA//PIK3CA//PI3K ALPHA
3208 1961 PTEN//LHERMITTE DUCLOS DISEASE//COWDEN SYNDROME
5369 1565 PDK1//AKT ISOFORMS//AKT2
6016 1475 INSULIN RECEPTOR SUBSTRATE//INSULIN RECEPTOR SUBSTRATE 1//IRS 1
7283 1309 PIKFYVE//PTDINS5P//GOLPH3
14030 733 SHIP2//INOSITOL 5 PHOSPHATASE//SHIP1
15283 651 S6K2//S6 KINASE//RIBOSOMAL S6 KINASE 2 S6K2
19194 451 BIOL CHEMBUNKYO KU//DEMETHOXYVIRIDIN//2 4 MORPHOLINYL 8 PHENYLCHROMONE
25041 244 LOWE SYNDROME//OCULOCEREBRORENAL SYNDROME//OCRL1

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 PTEN Author keyword 365 36% 6% 817
2 MTOR Author keyword 202 24% 6% 746
3 LHERMITTE DUCLOS DISEASE Author keyword 143 87% 1% 71
4 COWDEN SYNDROME Author keyword 105 66% 1% 97
5 PI3K Author keyword 93 20% 3% 410
6 AKT Author keyword 88 11% 6% 729
7 RAPAMYCIN Author keyword 81 18% 3% 405
8 P110 ALPHA Author keyword 70 89% 0% 32
9 SHIP2 Author keyword 68 82% 0% 40
10 PIK3CA Author keyword 63 38% 1% 133

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 PTEN 365 36% 6% 817 Search PTEN Search PTEN
2 MTOR 202 24% 6% 746 Search MTOR Search MTOR
3 LHERMITTE DUCLOS DISEASE 143 87% 1% 71 Search LHERMITTE+DUCLOS+DISEASE Search LHERMITTE+DUCLOS+DISEASE
4 COWDEN SYNDROME 105 66% 1% 97 Search COWDEN+SYNDROME Search COWDEN+SYNDROME
5 PI3K 93 20% 3% 410 Search PI3K Search PI3K
6 AKT 88 11% 6% 729 Search AKT Search AKT
7 RAPAMYCIN 81 18% 3% 405 Search RAPAMYCIN Search RAPAMYCIN
8 P110 ALPHA 70 89% 0% 32 Search P110+ALPHA Search P110+ALPHA
9 SHIP2 68 82% 0% 40 Search SHIP2 Search SHIP2
10 PIK3CA 63 38% 1% 133 Search PIK3CA Search PIK3CA

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of publ.
in class
1 MAMMALIAN TARGET 573 31% 12% 1566
2 PHOSPHOINOSITIDE 3 KINASE 297 24% 8% 1061
3 PROTEIN KINASE B 260 29% 6% 755
4 PHOSPHATIDYLINOSITOL 3 KINASE 257 15% 12% 1618
5 PTEN MMAC1 237 71% 1% 192
6 COWDEN DISEASE 189 60% 2% 206
7 MTOR 171 25% 4% 588
8 P70 S6 KINASE 166 32% 3% 422
9 PTEN MMAC1 GENE 163 79% 1% 106
10 TUMOR SUPPRESSOR PTEN 162 42% 2% 303

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
mTOR Signaling in Growth Control and Disease 2012 1325 172 67%
mTOR: from growth signal integration to cancer, diabetes and ageing 2011 1183 170 52%
PI3K and cancer: lessons, challenges and opportunities 2014 149 215 51%
AKT/PKB signaling: Navigating downstream 2007 2173 109 46%
Targeting the phosphoinositide 3-kinase pathway in cancer 2009 779 195 81%
Targeting PI3K signalling in cancer: opportunities, challenges and limitations 2009 875 150 71%
Defining the role of mTOR in cancer 2007 1304 130 67%
TOR signaling in growth and metabolism 2006 2539 109 52%
PI3K in cancer: divergent roles of isoforms, modes of activation and therapeutic targeting 2015 9 195 80%
Making new contacts: the mTOR network in metabolism and signalling crosstalk 2014 77 81 67%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 SECT MOL SIGNAL TRANSDUCT 16 48% 0.2% 24
2 CLIN CANC GENET PROGRAM 15 31% 0.3% 41
3 INOSITIDE 14 31% 0.3% 37
4 STANLEY SHALOM ZIELONY NURSING EXCELLENCE 12 50% 0.1% 18
5 INOSITIDE SIGNALLING GRP 11 67% 0.1% 10
6 CRUK INOSITIDE 11 100% 0.0% 6
7 HIGH THROUGHPUT SCREENING MOL PHARMACOL 11 78% 0.1% 7
8 HUMAN CANC GENET GRP 10 26% 0.2% 32
9 STANLEY SHALOM ZIELONY NURSING 9 83% 0.0% 5
10 INFLAMMATORY CELL BIOL 9 67% 0.1% 8

Related classes at same level (level 2)


Rank Relatedness score Related classes
1 0.0000011693 ANGIOMYOLIPOMA//TUBEROUS SCLEROSIS//TUBEROUS SCLEROSIS COMPLEX
2 0.0000011180 AUTOPHAGY//BECLIN 1//LC3
3 0.0000011108 GLUCOSE TRANSPORTER//WARBURG EFFECT//GLUT1
4 0.0000010843 PHOSPHOLIPASE D//DIACYLGLYCEROL KINASE//PROTEIN KINASE C
5 0.0000009543 IRES//TRANSLATION INITIATION//EIF4E
6 0.0000009478 FOCAL ADHESION KINASE//INTEGRIN LINKED KINASE//FAK
7 0.0000008994 SIRT1//SIRTUIN//FOXM1
8 0.0000008867 PIM 2//TRANSLATIONALLY CONTROLLED TUMOR PROTEIN//TCTP
9 0.0000008830 COFFIN LOWRY SYNDROME//ERK5//JNK
10 0.0000008821 INSULIN DEGRADING ENZYME//GLYCOSYLPHOSPHATIDYLINOSITOL//NEPRILYSIN