Class information for:
Level 2: CELL CYCLE//CDK5//E2F

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
521 14318 46.4 90%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 3)


ID, lev.
above		 Publications Label for level above
244 42700 MERKEL CELL CARCINOMA//P53//JC VIRUS

Classes in level below (level 1)


ID, lev. below Publications Label for level below
2301 2220 E2F//P107//P130
3485 1894 CYCLIN D1//CYCLIN E//CCND1
3711 1847 P14ARF//P16//P16INK4A
3974 1795 CAK//CDC2//CYCLIN A1
5202 1589 SKP2//P27KIP1//P27
6779 1368 FLAVOPIRIDOL//CELL CYCLE REGULAT GRP//ROSCOVITINE
8348 1193 P21//P21WAF1 CIP1//WAF1
11814 888 CDK5//P35//CYCLIN DEPENDENT KINASE 5
13986 736 PEDIAT CHILDREN SURG//SOMATIC GENOME VARIATIONS//HUMAN PERIPHERAL CELLS
24786 252 UCN 01//7 HYDROXYSTAUROSPORINE//7 HYDROXYSTAUROSPORINE UCN 01
25390 235 CCNG2//CYCLIN G2//CYCLIN G
27801 181 ARID3B//JUMONJI//AT RICH INTERACTION DOMAIN
31665 120 GANKYRIN//P28GANK//PSMD10

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of publ.
in class
1 CELL CYCLE Author keyword 212 11% 13% 1801
2 CDK5 Author keyword 206 56% 2% 250
3 E2F Author keyword 200 49% 2% 300
4 CYCLIN D1 Author keyword 174 26% 4% 574
5 P27 Author keyword 154 36% 2% 345
6 CYCLIN DEPENDENT KINASE Author keyword 152 40% 2% 297
7 SKP2 Author keyword 145 63% 1% 145
8 P27KIP1 Author keyword 144 37% 2% 309
9 FLAVOPIRIDOL Author keyword 125 63% 1% 126
10 CDK Author keyword 103 39% 1% 205

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of publ.
in class		 LCSH search Wikipedia search
1 CELL CYCLE 212 11% 13% 1801 Search CELL+CYCLE Search CELL+CYCLE
2 CDK5 206 56% 2% 250 Search CDK5 Search CDK5
3 E2F 200 49% 2% 300 Search E2F Search E2F
4 CYCLIN D1 174 26% 4% 574 Search CYCLIN+D1 Search CYCLIN+D1
5 P27 154 36% 2% 345 Search P27 Search P27
6 CYCLIN DEPENDENT KINASE 152 40% 2% 297 Search CYCLIN+DEPENDENT+KINASE Search CYCLIN+DEPENDENT+KINASE
7 SKP2 145 63% 1% 145 Search SKP2 Search SKP2
8 P27KIP1 144 37% 2% 309 Search P27KIP1 Search P27KIP1
9 FLAVOPIRIDOL 125 63% 1% 126 Search FLAVOPIRIDOL Search FLAVOPIRIDOL
10 CDK 103 39% 1% 205 Search CDK Search CDK

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of publ.
in class
1 RETINOBLASTOMA PROTEIN 513 32% 9% 1348
2 DEPENDENT KINASE INHIBITOR 472 41% 6% 901
3 P27 305 57% 3% 360
4 S PHASE ENTRY 287 59% 2% 324
5 CDK INHIBITORS 281 42% 4% 520
6 P27KIP1 280 34% 5% 675
7 DEPENDENT KINASES 273 38% 4% 576
8 CYCLIN DEPENDENT KINASES 229 27% 5% 723
9 CELL CYCLE 212 10% 14% 1965
10 CYCLIN DEPENDENT KINASE 5 206 41% 3% 395

Journals


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 CELL DIVISION 3 13% 0% 24

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
The history and future of targeting cyclin-dependent kinases in cancer therapy 2015 11 176 68%
Cyclin D as a therapeutic target in cancer 2011 254 182 66%
Cancer cell cycles 1996 3982 180 69%
Cell cycle, CDKs and cancer: a changing paradigm 2009 832 164 35%
The Cdk inhibitor p27 in human cancer: prognostic potential and relevance to anticancer therapy 2008 387 198 71%
p21 in cancer: intricate networks and multiple activities 2009 602 223 47%
Cyclin-dependent kinase pathways as targets for cancer treatment 2006 455 185 79%
Molecular mechanisms underlying RB protein function 2013 67 89 76%
The regulation of E2F by pRB-family proteins 1998 1610 183 89%
CDK inhibitors: Cell cycle regulators and beyond 2008 397 133 60%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 CELL CYCLE REGULAT GRP 37 67% 0.2% 34
2 DTP CLIN TRIALS UNIT 15 88% 0.0% 7
3 MOLEC BIOL MB7 14 100% 0.0% 7
4 MOL THER EUT UNIT 13 58% 0.1% 15
5 HOTEL RECH 12 86% 0.0% 6
6 PERINATOGYNECOL 11 69% 0.1% 9
7 TUMOR CELL BIOL 9 11% 0.6% 82
8 SBARRO CANC MOL MED 9 13% 0.4% 64
9 PEDIAT CHILDREN SURG 7 56% 0.1% 9
10 GENET CANC GRP 6 80% 0.0% 4

Related classes at same level (level 2)


Rank Relatedness score Related classes
1 0.0000023865 RETINOBLASTOMA//CHEMOREDUCTION//OPHTHALM ONCOL SERV
2 0.0000018057 P73//MDM2//P53
3 0.0000012232 ASTROCYTE ELEVATED GENE 1//AEG 1//DREF
4 0.0000011144 ID 1//NRSF//MYC
5 0.0000010094 GEMININ//DNA REPLICATION//CDC6
6 0.0000009608 E1A//BIOL MOL ELADIO VINUELA//PHAGE PHI 29
7 0.0000008903 MIDBLASTULA TRANSITION//FROG OOCYTE//GLYCOGEN BODY
8 0.0000007580 ARECA NUT//ORAL SUBMUCOUS FIBROSIS//ORAL CANCER
9 0.0000007513 KINETOCHORE//MITOSIS//CENTROSOME
10 0.0000007276 PROTEASOME//UBIQUITIN//NEDD8