Class information for:
Level 2: STATINS//EZETIMIBE//SIMVASTATIN

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
408 16067 37.8 78%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 3)


ID, lev.
above		 Publications Label for level above
118 66796 JOURNAL OF LIPID RESEARCH//HIGH DENSITY LIPOPROTEIN//STATINS

Classes in level below (level 1)


ID, lev. below Publications Label for level below
233 3776 STATINS//LOW DENSITY LIPOPROTEIN CHOLESTEROL//ATORVASTATIN
3781 1833 FLUVASTATIN//PLEIOTROPIC EFFECTS//HMG COA REDUCTASE INHIBITOR
4101 1771 OATP1B1//SLCO1B1//OATP
6263 1442 PRAVASTATIN//HMG COA REDUCTASE INHIBITOR//COMPACTIN
8325 1195 LAROPIPRANT//NIACIN//HM74A
9022 1128 LOVASTATIN//BB BIOCYT//PEDIAT PNEUMONOL ALLERG DIS HEMATOL
10393 1001 FENOFIBRIC ACID//FENOFIBRATE//FIBRATES
10828 964 STATIN MYOPATHY//STATIN INTOLERANCE//MYALGIA
11704 897 EZETIMIBE//CHOLESTEROL ABSORPTION INHIBITOR//COLESEVELAM
13885 743 P DIS TB INTERNAL MED//3 HYDROXY 3 METHYLGLUTARYL CO ENZYME A REDUCTASE INHIBITOR//INTER PROGRAM IMMUNOL
18625 477 NK 104//PITAVASTATIN//CAS 147526 32 7
18678 474 ROSUVASTATIN CALCIUM//ATORVASTATIN CALCIUM//EZETIMIBE GLUCURONIDE
21265 366 PROBUCOL//AGI 1067//SUCCINOBUCOL

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of publ.
in class
1 STATINS Author keyword 890 37% 12% 1896
2 EZETIMIBE Author keyword 494 65% 3% 466
3 SIMVASTATIN Author keyword 406 41% 5% 780
4 STATIN Author keyword 388 37% 5% 837
5 ATORVASTATIN Author keyword 358 41% 4% 684
6 PRAVASTATIN Author keyword 291 53% 2% 387
7 HMG COA REDUCTASE INHIBITORS Author keyword 258 55% 2% 322
8 ROSUVASTATIN Author keyword 192 47% 2% 299
9 HMG COA REDUCTASE INHIBITOR Author keyword 183 54% 1% 234
10 FLUVASTATIN Author keyword 150 52% 1% 204

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of publ.
in class		 LCSH search Wikipedia search
1 STATINS 890 37% 12% 1896 Search STATINS Search STATINS
2 EZETIMIBE 494 65% 3% 466 Search EZETIMIBE Search EZETIMIBE
3 SIMVASTATIN 406 41% 5% 780 Search SIMVASTATIN Search SIMVASTATIN
4 STATIN 388 37% 5% 837 Search STATIN Search STATIN
5 ATORVASTATIN 358 41% 4% 684 Search ATORVASTATIN Search ATORVASTATIN
6 PRAVASTATIN 291 53% 2% 387 Search PRAVASTATIN Search PRAVASTATIN
7 HMG COA REDUCTASE INHIBITORS 258 55% 2% 322 Search HMG+COA+REDUCTASE+INHIBITORS Search HMG+COA+REDUCTASE+INHIBITORS
8 ROSUVASTATIN 192 47% 2% 299 Search ROSUVASTATIN Search ROSUVASTATIN
9 HMG COA REDUCTASE INHIBITOR 183 54% 1% 234 Search HMG+COA+REDUCTASE+INHIBITOR Search HMG+COA+REDUCTASE+INHIBITOR
10 FLUVASTATIN 150 52% 1% 204 Search FLUVASTATIN Search FLUVASTATIN

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of publ.
in class
1 PRAVASTATIN 1255 50% 11% 1825
2 SIMVASTATIN 928 43% 10% 1666
3 COA REDUCTASE INHIBITORS 665 45% 7% 1105
4 ATORVASTATIN 576 38% 7% 1198
5 PRIMARY HYPERCHOLESTEROLEMIA 574 75% 3% 415
6 LOVASTATIN 563 49% 5% 835
7 AVERAGE CHOLESTEROL LEVELS 451 51% 4% 626
8 HMG COA REDUCTASE 375 35% 5% 857
9 STATINS 361 31% 6% 979
10 SCANDINAVIAN SIMVASTATIN SURVIVAL 282 55% 2% 357

Journals


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 JOURNAL OF CLINICAL LIPIDOLOGY 28 23% 1% 110
2 ATHEROSCLEROSIS SUPPLEMENTS 11 19% 0% 51
3 AMERICAN JOURNAL OF CARDIOVASCULAR DRUGS 7 13% 0% 48
4 CURRENT ATHEROSCLEROSIS REPORTS 6 10% 0% 57
5 JOURNAL OF CARDIOVASCULAR RISK 3 11% 0% 27

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Risk of Incident Diabetes With Intensive-Dose Compared With Moderate-Dose Statin Therapy A Meta-analysis 2011 326 30 70%
Membrane transporters in drug development 2010 789 205 35%
Impact of OATP transporters on pharmacokinetics 2009 262 147 86%
Organic Anion Transporting Polypeptide 1B1: a Genetically Polymorphic Transporter of Major Importance for Hepatic Drug Uptake 2011 164 220 79%
Statins and All-Cause Mortality in High-Risk Primary Prevention A Meta-analysis of 11 Randomized Controlled Trials Involving 65 229 Participants 2010 188 31 84%
Statin myotoxicity: A review of genetic susceptibility factors 2014 27 127 77%
Drug interactions with lipid-lowering drugs: Mechanisms and clinical relevance 2006 325 143 88%
Pleiotropic Effects of Statins - Basic Research and Clinical Perspectives 2010 207 121 60%
Statins and cancer risk - A meta-analysis 2006 329 42 83%
Effect of statins on risk of coronary disease - A meta-analysis of randomized controlled trials 1999 758 41 73%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 MOL PHARMACOKINET 35 39% 0.4% 71
2 INTERNAL MED CLIN PHARMACOL 22 35% 0.3% 51
3 OFF HLTH PROMOT DIS PREVENT 18 55% 0.1% 23
4 HEART DIS PREVENT CLIN 14 64% 0.1% 14
5 SECT ATHEROSCLEROSIS LIPID 9 83% 0.0% 5
6 LIPID CLIN 9 13% 0.4% 61
7 RIKEN INNOVAT 8 43% 0.1% 15
8 VASC MED ATHEROSCLEROSIS UNIT 8 29% 0.1% 24
9 TOKYO NEW DRUG S 1 8 60% 0.1% 9
10 ANAL COST EFFECT CARE 8 39% 0.1% 15

Related classes at same level (level 2)


Rank Relatedness score Related classes
1 0.0000015039 MEDICATION ADHERENCE//JOURNAL OF HUMAN HYPERTENSION//BLOOD PRESSURE CONTROL
2 0.0000014217 CHOLESTERYL ESTER TRANSFER PROTEIN//JOURNAL OF LIPID RESEARCH//HIGH DENSITY LIPOPROTEIN
3 0.0000011512 POLICOSANOL//OCTACOSANOL//DECALEPIS HAMILTONII
4 0.0000010108 PLANT STEROLS//PHYTOSTEROLS//SITOSTANOL
5 0.0000009842 BOVINE HIPPOCAMPUS//SEROTONIN1A RECEPTOR//P MPPF
6 0.0000008979 INFLAMMASOME//C REACTIVE PROTEIN//NLRP3
7 0.0000008852 INTIMA MEDIA THICKNESS//CAROTID ARTERIES//VASA VASORUM
8 0.0000008688 PEPT1//PEPT2//HPEPT1
9 0.0000007866 LIPOPROTEINA//APOLIPOPROTEINA//LIPOPROTEIN A
10 0.0000007838 LOX 1//OXIDIZED LDL//SCAVENGER RECEPTOR