Class information for:
Level 2: FOXP3//CTLA 4//REGULATORY T CELLS

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
353 16852 47.7 94%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 3)


ID, lev.
above		 Publications Label for level above
18 119602 JOURNAL OF IMMUNOLOGY//IMMUNOL//DENDRITIC CELLS

Classes in level below (level 1)


ID, lev. below Publications Label for level below
105 4258 FOXP3//REGULATORY T CELLS//REGULATORY T CELL
1794 2413 INTERDISCIPLINARY PROGRAM IMMUNOL//INTEGRATED IMMUNOL VACCINE//T CELL COMPETITION
3827 1826 CD28//CD80//B7
3840 1824 B7 H4//PD 1//PD L1
6162 1457 4 1BB//OX40//CD137
6333 1432 CTLA 4//IPILIMUMAB//CYTOTOXIC T LYMPHOCYTE ANTIGEN 4
10617 981 INTERLEUKIN 21//IL 21//FOLLICULAR HELPER T CELLS
15120 661 REGULATORY B CELLS//CD40 ACTIVATED B CELLS//REGULATORY B CELL
18266 495 TIM 3//GALECTIN 9//TIM 1
19159 453 T CELL METABOLISM//UAB MITOCHONDRIAL MED//BZ 423
19757 427 SECRETION INHIBITION//RNF13//PROTEASE ASSOCIATED DOMAIN
22748 314 ICOS//B7RP 1//ICOSL
22825 311 MULTI ORGAN TRANSPLANTAT PROGRAM//TROGOCYTOSIS//CLINICIAN SCIENTIST TRAINING PROGRAM

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 FOXP3 Author keyword 348 43% 4% 627
2 CTLA 4 Author keyword 348 59% 2% 388
3 REGULATORY T CELLS Author keyword 298 28% 5% 905
4 COSTIMULATION Author keyword 284 45% 3% 473
5 PD 1 Author keyword 203 55% 1% 251
6 B7 H4 Author keyword 168 93% 0% 64
7 TIM 3 Author keyword 149 79% 1% 95
8 CD28 Author keyword 147 41% 2% 275
9 4 1BB Author keyword 139 78% 1% 93
10 PD L1 Author keyword 136 58% 1% 158

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 FOXP3 348 43% 4% 627 Search FOXP3 Search FOXP3
2 CTLA 4 348 59% 2% 388 Search CTLA+4 Search CTLA+4
3 REGULATORY T CELLS 298 28% 5% 905 Search REGULATORY+T+CELLS Search REGULATORY+T+CELLS
4 COSTIMULATION 284 45% 3% 473 Search COSTIMULATION Search COSTIMULATION
5 PD 1 203 55% 1% 251 Search PD+1 Search PD+1
6 B7 H4 168 93% 0% 64 Search B7+H4 Search B7+H4
7 TIM 3 149 79% 1% 95 Search TIM+3 Search TIM+3
8 CD28 147 41% 2% 275 Search CD28 Search CD28
9 4 1BB 139 78% 1% 93 Search 4+1BB Search 4+1BB
10 PD L1 136 58% 1% 158 Search PD+L1 Search PD+L1

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of publ.
in class
1 TRANSCRIPTION FACTOR FOXP3 832 56% 6% 1020
2 IMMUNOLOGICAL SELF TOLERANCE 788 56% 6% 957
3 CD28 642 55% 5% 810
4 CTLA 4 599 56% 4% 730
5 B7 FAMILY 513 74% 2% 382
6 CUTTING EDGE 372 18% 11% 1899
7 FOXP3 319 42% 3% 585
8 CHRONIC VIRAL INFECTION 314 50% 3% 458
9 B7 H1 296 77% 1% 201
10 PD 1 286 61% 2% 306

Journals


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 IMMUNITY 43 11% 2% 356
2 NATURE IMMUNOLOGY 25 11% 1% 218
3 CANCER IMMUNOLOGY RESEARCH 10 18% 0% 49

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
The blockade of immune checkpoints in cancer immunotherapy 2012 699 119 80%
Regulatory T cells and immune tolerance 2008 1357 112 75%
Regulatory T Cells: Mechanisms of Differentiation and Function 2012 476 227 72%
FOXP3(+) regulatory T cells in the human immune system 2010 627 117 82%
PD-1 and its ligands in tolerance and immunity 2008 859 149 85%
The evolution of checkpoint blockade as a cancer therapy: what's here, what's next? 2015 19 177 67%
Mechanisms of Foxp3(+) T Regulatory Cell-Mediated Suppression 2009 701 62 84%
The future of immune checkpoint therapy 2015 15 63 78%
Naturally arising CD4(+) regulatory T cells for immunologic self-tolerance and negative control of immune responses 2004 2036 120 73%
Naturally arising Foxp3-expressing CD25(+) CD4(+) regulatory T cells in immunological tolerance to self and non-self 2005 1516 102 81%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 LUDWIG CANC IMMUNOTHER Y 47 56% 0.3% 57
2 EMORY VACCINE 40 19% 1.1% 184
3 IMMUNOMODULAT 29 32% 0.4% 75
4 EARLE A CHILES 25 33% 0.4% 64
5 INTERDISCIPLINARY PROGRAM IMMUNOL 22 24% 0.5% 81
6 RD CANC THER EUT 21 73% 0.1% 16
7 UNIT IMMUNE HOMEOSTASIS 19 71% 0.1% 15
8 IMMUNOL IMMUNOPATHOL 17 29% 0.3% 51
9 INTEGRATED IMMUNOL VACCINE 17 72% 0.1% 13
10 CELL SIGNALLING SECT 16 65% 0.1% 15

Related classes at same level (level 2)


Rank Relatedness score Related classes
1 0.0000020851 ORAL TOLERANCE//DC SIGN//DENDRITIC CELLS
2 0.0000018825 IMMUNOTHERAPY//DENDRITIC CELLS//CANCER IMMUNOLOGY IMMUNOTHERAPY
3 0.0000015745 INTERLEUKIN 18//IL 18//IL 17
4 0.0000013053 CD40//BAFF//CD40 LIGAND
5 0.0000011996 TRANSPLANTATION//HAND TRANSPLANTATION//COMPOSITE TISSUE ALLOTRANSPLANTATION
6 0.0000011584 X LINKED AGAMMAGLOBULINEMIA//BRUTONS TYROSINE KINASE//BTK
7 0.0000009977 HLA G//KIR//NKG2D
8 0.0000009079 STAT3//INTERLEUKIN 7//SOCS
9 0.0000008078 IMMUNOSENESCENCE//NUTRIENT MIXTURE//IMMUNITY & AGEING
10 0.0000007854 TYPE 1 DIABETES//DIABETIC KETOACIDOSIS//BARBARA DAVIS CHILDHOOD DIABET