Class information for:
Level 2: DNA METHYLATION//EPIGENETICS//HISTONE DEACETYLASE INHIBITOR

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
348 16958 49.3 88%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 3)


ID, lev.
above		 Publications Label for level above
96 73697 DNA METHYLATION//FRAGILE X SYNDROME//RETT SYNDROME

Classes in level below (level 1)


ID, lev. below Publications Label for level below
264 3709 HISTONE DEACETYLASE INHIBITOR//HISTONE DEACETYLASE INHIBITORS//HISTONE DEACETYLASE
2565 2134 RRBS//CPG ISLANDS//METHYLTRANSFERASE ACTIVITY
3145 1972 DNMT3B//DNA METHYLTRANSFERASE//DNMT1
6440 1418 DNA 5 METHYLCYTOSINE//DNA METHYLASE//5 METHYLDCMP DEAMINASE
6762 1371 SACKLER PROGRAM EPIGENET DEV PSYCHOBIOL//AGING COGNIT DIS//BONNEY 106
7506 1281 EPIGENETIC EPIDEMIOLOGY//EWAS//EPIGENETICS
10848 962 RASSF1A//RASSF2//RASSF1
13046 800 5 HYDROXYMETHYLCYTOSINE//5HMC//5 CARBOXYLCYTOSINE
14006 735 ZEBULARINE//DECITABINE//FAZARABINE
16473 587 TRAUMA EMERGENCY SURG SURG CRIT CAREMASSAC//HUNAN MED EPIGEN//TOLERANCE BREAKDOWN
16984 560 TRANSGENERATIONAL//METASTABLE EPIALLELE//TRANSGENERATIONAL EPIGENETIC INHERITANCE
19369 444 CHFR//EPIGENETCANC//P41 ARC
21009 376 DAP KINASE//DEATH ASSOCIATED PROTEIN KINASE//DAPK
28366 170 UHRF1//ICBP90//UHRF2
29272 155 METABOLIC MEMORY//HYPERGLYCEMIC MEMORY//EPIGEN PROFILING IL
30087 143 MIR 1260B//NOUVEL HOP ESTAING//DIETARY COMPOUNDS
30211 141 RLGS//RESTRICTION LANDMARK GENOMIC SCANNING//GENOMIC SCANNING

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of publ.
in class
1 DNA METHYLATION Author keyword 1004 32% 15% 2595
2 EPIGENETICS Author keyword 421 22% 10% 1658
3 HISTONE DEACETYLASE INHIBITOR Author keyword 348 56% 2% 422
4 HISTONE DEACETYLASE INHIBITORS Author keyword 258 57% 2% 304
5 HISTONE DEACETYLASE Author keyword 256 40% 3% 495
6 HDAC INHIBITOR Author keyword 180 56% 1% 221
7 DNA METHYLTRANSFERASE Author keyword 138 45% 1% 233
8 METHYLATION Author keyword 137 15% 5% 855
9 RASSF1A Author keyword 130 62% 1% 136
10 5 HYDROXYMETHYLCYTOSINE Author keyword 127 73% 1% 97

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of publ.
in class		 LCSH search Wikipedia search
1 DNA METHYLATION 1004 32% 15% 2595 Search DNA+METHYLATION Search DNA+METHYLATION
2 EPIGENETICS 421 22% 10% 1658 Search EPIGENETICS Search EPIGENETICS
3 HISTONE DEACETYLASE INHIBITOR 348 56% 2% 422 Search HISTONE+DEACETYLASE+INHIBITOR Search HISTONE+DEACETYLASE+INHIBITOR
4 HISTONE DEACETYLASE INHIBITORS 258 57% 2% 304 Search HISTONE+DEACETYLASE+INHIBITORS Search HISTONE+DEACETYLASE+INHIBITORS
5 HISTONE DEACETYLASE 256 40% 3% 495 Search HISTONE+DEACETYLASE Search HISTONE+DEACETYLASE
6 HDAC INHIBITOR 180 56% 1% 221 Search HDAC+INHIBITOR Search HDAC+INHIBITOR
7 DNA METHYLTRANSFERASE 138 45% 1% 233 Search DNA+METHYLTRANSFERASE Search DNA+METHYLTRANSFERASE
8 METHYLATION 137 15% 5% 855 Search METHYLATION Search METHYLATION
9 RASSF1A 130 62% 1% 136 Search RASSF1A Search RASSF1A
10 5 HYDROXYMETHYLCYTOSINE 127 73% 1% 97 Search 5+HYDROXYMETHYLCYTOSINE Search 5+HYDROXYMETHYLCYTOSINE

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of publ.
in class
1 SUBEROYLANILIDE HYDROXAMIC ACID 802 65% 4% 762
2 DNA METHYLATION 612 18% 18% 3015
3 5 HYDROXYMETHYLCYTOSINE 482 73% 2% 368
4 5 METHYLCYTOSINE 453 59% 3% 513
5 HISTONE DEACETYLASE INHIBITORS 397 32% 6% 1044
6 HDAC INHIBITORS 391 65% 2% 369
7 HYPERMETHYLATION 374 30% 6% 1050
8 DE NOVO METHYLATION 369 51% 3% 523
9 TRICHOSTATIN A 343 50% 3% 500
10 MAMMALIAN DNA 291 66% 2% 267

Journals


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 EPIGENETICS 142 34% 2% 338
2 EPIGENOMICS 77 44% 1% 132
3 CLINICAL EPIGENETICS 39 41% 0% 74
4 EPIGENETICS & CHROMATIN 6 17% 0% 34

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Function and information content of DNA methylation 2015 26 115 69%
Functions of DNA methylation: islands, start sites, gene bodies and beyond 2012 627 96 65%
Reversing DNA Methylation: Mechanisms, Genomics, and Biological Functions 2014 104 209 77%
New and emerging HDAC inhibitors for cancer treatment 2014 90 123 76%
Epigenetics and human obesity 2015 11 111 72%
Anticancer activities of histone deacetylase inhibitors 2006 1390 198 73%
DNA methylation: roles in mammalian development 2013 277 196 48%
TET enzymes, TDG and the dynamics of DNA demethylation 2013 148 99 82%
Molecular origins of cancer: Epigenetics in cancer 2008 1320 91 44%
The fundamental role of epigenetic events in cancer 2002 2978 107 53%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 EPIGENET 62 29% 1.1% 183
2 CANC EPIGENET 42 30% 0.7% 117
3 EPIGENET GENE REGULAT CANC SECT 38 93% 0.1% 14
4 SACKLER PROGRAM EPIGENET DEV PSYCHOBIOL 38 86% 0.1% 19
5 KREMBIL FAMILY EPIGENET 20 63% 0.1% 20
6 STAT GENOM GRP 19 71% 0.1% 15
7 AG TUMORGENET MED FAK 18 89% 0.0% 8
8 EXCELLENCE MOL GENET CANC HUMAN DIS 17 49% 0.1% 25
9 ENVIRONM EPIGENET 16 56% 0.1% 19
10 GRP EPIGENET 15 67% 0.1% 14

Related classes at same level (level 2)


Rank Relatedness score Related classes
1 0.0000025846 GENOMIC IMPRINTING//H19//BECKWITH WIEDEMANN SYNDROME
2 0.0000024380 PROTEIN KINASE D//PROTEIN KINASE D PKD//MEF2C
3 0.0000018188 XIST//X CHROMOSOME INACTIVATION//TSIX
4 0.0000011853 CHROMATIN//EZH2//NUCLEOSOME
5 0.0000010595 RETT SYNDROME//MECP2//MECP2 GENE
6 0.0000008841 MASPIN//RARRES3//TIG3
7 0.0000007816 SIRT1//SIRTUIN//FOXM1
8 0.0000006724 HUMAN ENDOGENOUS RETROVIRUS//ADAR//ENDOGENOUS RETROVIRUS
9 0.0000006600 MICROSATELLITE INSTABILITY//LYNCH SYNDROME//HNPCC
10 0.0000006474 BRANCHIO OCULO FACIAL SYNDROME//RIZ1//BCL6