Class information for:
Level 2: CAMPTOTHECIN//SN 38//TOPOTECAN

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
2795 2580 34.3 75%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 3)


ID, lev.
above		 Publications Label for level above
499 19953 DIHYDROPYRIMIDINE DEHYDROGENASE//5 FLUOROURACIL//THYMIDINE PHOSPHORYLASE

Classes in level below (level 1)


ID, lev. below Publications Label for level below
2077 2298 CAMPTOTHECIN//SN 38//TOPOTECAN
27015 197 NOTHAPODYTES FOETIDA//CAMPTOTHECA ACUMINATA//OPHIORRHIZA PUMILA
33766 85 CHROMONE ALKALOIDS//ROHITUKINE//LDOC1

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 CAMPTOTHECIN Author keyword 226 39% 18% 457
2 SN 38 Author keyword 108 55% 5% 137
3 TOPOTECAN Author keyword 107 33% 10% 267
4 CPT 11 Author keyword 61 36% 5% 138
5 9 NITROCAMPTOTHECIN Author keyword 53 78% 1% 35
6 CAMPTOTHECINS Author keyword 47 61% 2% 50
7 9 AMINOCAMPTOTHECIN Author keyword 47 79% 1% 30
8 HOMOCAMPTOTHECIN Author keyword 41 87% 1% 20
9 IRINOTECAN Author keyword 36 13% 10% 248
10 NOTHAPODYTES FOETIDA Author keyword 24 68% 1% 21

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 CAMPTOTHECIN 226 39% 18% 457 Search CAMPTOTHECIN Search CAMPTOTHECIN
2 SN 38 108 55% 5% 137 Search SN+38 Search SN+38
3 TOPOTECAN 107 33% 10% 267 Search TOPOTECAN Search TOPOTECAN
4 CPT 11 61 36% 5% 138 Search CPT+11 Search CPT+11
5 9 NITROCAMPTOTHECIN 53 78% 1% 35 Search 9+NITROCAMPTOTHECIN Search 9+NITROCAMPTOTHECIN
6 CAMPTOTHECINS 47 61% 2% 50 Search CAMPTOTHECINS Search CAMPTOTHECINS
7 9 AMINOCAMPTOTHECIN 47 79% 1% 30 Search 9+AMINOCAMPTOTHECIN Search 9+AMINOCAMPTOTHECIN
8 HOMOCAMPTOTHECIN 41 87% 1% 20 Search HOMOCAMPTOTHECIN Search HOMOCAMPTOTHECIN
9 IRINOTECAN 36 13% 10% 248 Search IRINOTECAN Search IRINOTECAN
10 NOTHAPODYTES FOETIDA 24 68% 1% 21 Search NOTHAPODYTES+FOETIDA Search NOTHAPODYTES+FOETIDA

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 NSC 100880 193 79% 5% 125
2 CAMPTOTHECIN 180 27% 22% 577
3 CPT 11 168 39% 13% 339
4 DNA TOPOISOMERASE I 164 34% 15% 399
5 PLANT ANTITUMOR AGENTS 145 73% 4% 110
6 CARBOXYLATE FORMS 144 89% 3% 65
7 TOPOISOMERASE I INHIBITOR 123 58% 5% 140
8 RING MODIFIED CAMPTOTHECIN 115 83% 3% 66
9 SN 38 101 53% 5% 133
10 20S CAMPTOTHECIN 99 88% 2% 46

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Perspectives on Biologically Active Camptothecin Derivatives 2015 1 115 74%
Cancer Therapies Utilizing the Camptothecins: A Review of the in Vivo Literature 2010 84 285 66%
Clinical pharmacokinetics and metabolism of irinotecan (CPT-11) 2001 339 132 67%
Current perspectives on the clinical experience, pharmacology, and continued development of the camptothecins 2002 271 155 71%
Camptothecin: current perspectives 2004 204 133 61%
Review Camptothecin: Current Perspectives 2006 98 94 71%
Towards new anticancer drugs: a decade of advances in synthesis of camptothecins and related alkaloids 2003 130 118 80%
Camptothecins - A review of their chemotherapeutic potential 2002 141 144 63%
Chromone and Flavonoid Alkaloids: Occurrence and Bioactivity 2012 50 36 25%
Camptothecin and its analogues: a review on their chemotherapeutic potential 2005 44 67 82%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 STEHLIN FDN CANC 13 69% 0.4% 11
2 DANIEL DEN HOED KLIN 9 26% 1.2% 31
3 CAROLINA CANC NANOTECHOL EXCELLENCE 4 75% 0.1% 3
4 PEDIAT PHARMACOKINET THER EUT 3 17% 0.7% 18
5 GYNECOL ONCOL OUTREACH PROGRAM 3 100% 0.1% 3
6 JOINT GREEN CHEM 3 60% 0.1% 3
7 PROGRAM MOL THER EUT DRUG DISCOVERY 2 33% 0.2% 6
8 MED ON AB EXPT CHEMOTHER Y PHARMACOL 2 67% 0.1% 2
9 PLANT BIOTECHNOL SECONDARY PROD SECT 2 27% 0.2% 6
10 EXPT CHEMOTHER Y PHARMACOL 2 33% 0.2% 4

Related classes at same level (level 2)


Rank Relatedness score Related classes
1 0.0000025614 FLUOROQUINOLONES//CIPROFLOXACIN//QUINOLONES
2 0.0000018283 DIHYDROPYRIMIDINE DEHYDROGENASE//5 FLUOROURACIL//THYMIDINE PHOSPHORYLASE
3 0.0000017435 HPMA COPOLYMERS//HPMA COPOLYMER//PEGYLATION
4 0.0000015824 INTRAPERITONEAL CHEMOTHERAPY//CYTOREDUCTIVE SURGERY//PERITONEAL CARCINOMATOSIS
5 0.0000015707 SMALL CELL LUNG CANCER//BOMBESIN//GASTRIN RELEASING PEPTIDE
6 0.0000012303 KERNICTERUS//BILIRUBIN//HYPERBILIRUBINEMIA
7 0.0000010881 SOLID LIPID NANOPARTICLES//NANOSTRUCTURED LIPID CARRIERS//NANOSUSPENSION
8 0.0000010654 CONVECTION ENHANCED DELIVERY//GLIADEL//CARMUSTINE WAFERS
9 0.0000009714 P GLYCOPROTEIN//MULTIDRUG RESISTANCE//ABCG2
10 0.0000009237 BUTYRYLCHOLINESTERASE//ACETYLCHOLINESTERASE//BIS7 TACRINE