Class information for:
Level 2: ELAFIN//SLPI//SECRETORY LEUKOCYTE PROTEASE INHIBITOR

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
2487 3478 32.3 57%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 3)


ID, lev.
above		 Publications Label for level above
25 108416 RESPIRATORY SYSTEM//CYSTIC FIBROSIS//CHRONIC OBSTRUCTIVE PULMONARY DISEASE

Classes in level below (level 1)


ID, lev. below Publications Label for level below
4608 1683 ELAFIN//SLPI//SECRETORY LEUKOCYTE PROTEASE INHIBITOR
12939 807 PROTEINASE K INHIBITOR//HUMAN LEUKOCYTE ELASTASE//HUMAN LEUKOCYTE ELASTASE HLE
24004 273 AMINONAPHTHALENESULFONAMIDES//ORTHO AMINOBENZOIC ACID//UMR5616LEDSS
26177 215 NAFAMOSTAT MESILATE//PHARM PHARMACEUT HIGASHINADA KU//MED HOSP PHARM CHUO KU
27128 194 AMIDOLYSIS//ELASTASE ALPHA1 PROTEINASE INHIBITOR//CLOT LYSIS ASSAY
30073 143 ALLIED MED SCI SUMA KU//MED FUKUSHIMA KU//TARUMI KU
32852 101 MUCOPOLYSACCHARIDE POLYSULFATE//CAS 530 78 9//PERFUSED PIG EAR
34795 62 FIBRINOGEN THROMBIN CLOTTING//FIBRIN ALPHA CHAIN//COLLAGEN RELATED SYNTHETIC PEPTIDE

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 ELAFIN Author keyword 112 80% 2% 69
2 SLPI Author keyword 55 63% 2% 55
3 SECRETORY LEUKOCYTE PROTEASE INHIBITOR Author keyword 51 69% 1% 44
4 NEUTROPHIL ELASTASE Author keyword 33 26% 3% 109
5 SIVELESTAT Author keyword 22 55% 1% 28
6 TRAPPIN 2 Author keyword 18 83% 0% 10
7 NEUTROPHIL ELASTASE INHIBITOR Author keyword 18 55% 1% 22
8 SECRETORY LEUKOCYTE PROTEINASE INHIBITOR Author keyword 17 75% 0% 12
9 ELASTASE Author keyword 14 10% 4% 124
10 NAFAMOSTAT MESILATE Author keyword 13 36% 1% 30

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 ELAFIN 112 80% 2% 69 Search ELAFIN Search ELAFIN
2 SLPI 55 63% 2% 55 Search SLPI Search SLPI
3 SECRETORY LEUKOCYTE PROTEASE INHIBITOR 51 69% 1% 44 Search SECRETORY+LEUKOCYTE+PROTEASE+INHIBITOR Search SECRETORY+LEUKOCYTE+PROTEASE+INHIBITOR
4 NEUTROPHIL ELASTASE 33 26% 3% 109 Search NEUTROPHIL+ELASTASE Search NEUTROPHIL+ELASTASE
5 SIVELESTAT 22 55% 1% 28 Search SIVELESTAT Search SIVELESTAT
6 TRAPPIN 2 18 83% 0% 10 Search TRAPPIN+2 Search TRAPPIN+2
7 NEUTROPHIL ELASTASE INHIBITOR 18 55% 1% 22 Search NEUTROPHIL+ELASTASE+INHIBITOR Search NEUTROPHIL+ELASTASE+INHIBITOR
8 SECRETORY LEUKOCYTE PROTEINASE INHIBITOR 17 75% 0% 12 Search SECRETORY+LEUKOCYTE+PROTEINASE+INHIBITOR Search SECRETORY+LEUKOCYTE+PROTEINASE+INHIBITOR
9 ELASTASE 14 10% 4% 124 Search ELASTASE Search ELASTASE
10 NAFAMOSTAT MESILATE 13 36% 1% 30 Search NAFAMOSTAT+MESILATE Search NAFAMOSTAT+MESILATE

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 ANTILEUKOPROTEASE 186 81% 3% 110
2 LEUKOPROTEASE INHIBITOR 161 89% 2% 73
3 HUMAN LEUKOCYTE ELASTASE 153 38% 9% 320
4 ELASTASE SPECIFIC INHIBITOR 127 72% 3% 100
5 LEUKOCYTE PROTEASE INHIBITOR 55 31% 4% 148
6 SLPI 53 79% 1% 34
7 CATHEPSIN G 52 21% 6% 224
8 HUSI I 51 91% 1% 21
9 ONO 5046 49 66% 1% 46
10 BETA LACTAM INHIBITORS 48 73% 1% 36

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
SLPI and elafin: one glove, many fingers 2006 130 167 65%
SYNTHETIC INHIBITORS OF ELASTASE 1994 201 197 67%
TISSUE DESTRUCTION BY NEUTROPHILS 1989 3609 59 19%
Neutrophil Elastase, Proteinase 3, and Cathepsin G as Therapeutic Targets in Human Diseases 2010 98 393 27%
ELASTASES AND EMPHYSEMA - CURRENT ASSESSMENT OF THE PROTEASE-ANTIPROTEASE HYPOTHESIS 1985 754 135 57%
Irreversible inhibitors of serine, cysteine, and threonine proteases 2002 478 656 23%
Anti-inflammatory and antimicrobial roles of secretory leukocyte protease inhibitor 2005 65 51 78%
The trappin gene family: proteins defined by an N-terminal transglutaminase substrate domain and a C-terminal four-disulphide core 1999 123 67 72%
Neutrophil elastase inhibitors: recent advances in the development of mechanism-based and nonelectrophilic inhibitors 2012 7 29 86%
Neutrophil serine proteases: specific regulators of inflammation 2006 280 99 18%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 ALLIED MED SCI SUMA KU 11 100% 0.2% 6
2 MED FUKUSHIMA KU 11 78% 0.2% 7
3 TARUMI KU 10 46% 0.5% 17
4 KOBE PROJECTS THROMBOSIS HAEMOSTASIS 6 80% 0.1% 4
5 COMP AIDED MOL MODELING 6 100% 0.1% 4
6 PHARM PHARMACEUT HIGASHINADA KU 3 100% 0.1% 3
7 MED HOSP PHARM CHUO KU 3 35% 0.2% 6
8 NUTR NISHI KU 2 38% 0.1% 5
9 NUTR TARUMI KU 2 67% 0.1% 2
10 U618 PROTEASES VECTORISAT PULM 2 67% 0.1% 2

Related classes at same level (level 2)


Rank Relatedness score Related classes
1 0.0000042000 ALPHA1 ANTITRYPSIN DEFICIENCY//ALPHA 1 ANTITRYPSIN//EMPHYSEMA
2 0.0000013954 PULMONARY MICROCIRCULATION//PRESSURE FLOW PLOTS//CHRONIC INSTRUMENTATION
3 0.0000011905 MARFAN SYNDROME//FIBRILLIN//LYSYL OXIDASE
4 0.0000011818 BOWMAN BIRK INHIBITOR//PROTEASE ACTIVATED RECEPTOR//CYCLOTIDES
5 0.0000011288 RAPID EQUILIBRIUM//UNSTABLE PRODUCT//ELECT ENGN ELECT AUTOMAT COMMUN
6 0.0000009277 SULTAMS//AMINOALKANESULFONIC ACID//BETA SULTAM
7 0.0000009153 CATHEPSIN B//CATHEPSIN K//CATHEPSIN D
8 0.0000007980 CARBENE COMPLEXES//1 BETA METHYLCARBAPENEM//AZETIDIN 2 ONES
9 0.0000007434 CARDIOPULMONARY BYPASS//APROTININ//PERFUSION-UK
10 0.0000007171 CHRONIC GRANULOMATOUS DISEASE//NADPH OXIDASE//FORMYL PEPTIDE RECEPTOR