Class information for:
Level 2: TRAMADOL//BREAKTHROUGH PAIN//MORPHINE 6 GLUCURONIDE

Basic class information

ID Publications Average number
of references
Avg. shr. active
ref. in WoS
1638 6431 31.5 66%



Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 3)



ID, lev.
above
Publications Label for level above
63 87056 ANESTHESIOLOGY//FIBROMYALGIA//PAIN

Classes in level below (level 1)



ID, lev. below Publications Label for level below
5260 1581 BREAKTHROUGH PAIN//OPIOID ROTATION//CANCER PAIN
5992 1478 MORPHINE 6 GLUCURONIDE//MORPHINE 3 GLUCURONIDE//MORPHINE GLUCURONIDES
8459 1182 TRAMADOL//O DESMETHYLTRAMADOL//TAPENTADOL
14293 713 OPRM1//A118G//OPRM1 GENE
15331 648 METHADONE//EDDP//2 ETHYLIDENE 1 5 DIMETHYL 3 3 DIPHENYLPYRROLIDINE
19616 432 NALBUPHINE//MEPTAZINOL//DEZOCINE
28331 170 NORMEPERIDINE//PETHIDINE//COMPLICATIONS NORPETHIDINE TOXICITY
30913 131 CONCEPTUAL SEARCHING//CURRICULUM HISTORY//DESIGNATED CANCER HOSPITAL
33184 96 KETOBEMIDONE//BUTYLENE CARBONATE//CATECHOL METABOLITE

Terms with highest relevance score



Rank Term Type of term Relevance score
(tfidf)
Class's shr.
of term's tot.
occurrences
Shr. of publ.
in class containing
term
Num. of
publ. in
class
1 TRAMADOL Author keyword 402 53% 8% 525
2 BREAKTHROUGH PAIN Author keyword 251 84% 2% 137
3 MORPHINE 6 GLUCURONIDE Author keyword 116 68% 2% 102
4 MORPHINE 3 GLUCURONIDE Author keyword 106 74% 1% 78
5 CANCER PAIN Author keyword 86 25% 5% 302
6 O DESMETHYLTRAMADOL Author keyword 86 96% 0% 26
7 OXYCODONE Author keyword 77 37% 3% 167
8 OPIOID ROTATION Author keyword 76 77% 1% 51
9 METHADONE Author keyword 65 17% 5% 352
10 TAPENTADOL Author keyword 62 67% 1% 56

Web of Science journal categories

Author Key Words



Rank Web of Science journal category Relevance score
(tfidf)
Class's shr.
of term's tot.
occurrences
Shr. of publ.
in class containing
term
Num. of
publ. in
class
LCSH search Wikipedia search
1 TRAMADOL 402 53% 8% 525 Search TRAMADOL Search TRAMADOL
2 BREAKTHROUGH PAIN 251 84% 2% 137 Search BREAKTHROUGH+PAIN Search BREAKTHROUGH+PAIN
3 MORPHINE 6 GLUCURONIDE 116 68% 2% 102 Search MORPHINE+6+GLUCURONIDE Search MORPHINE+6+GLUCURONIDE
4 MORPHINE 3 GLUCURONIDE 106 74% 1% 78 Search MORPHINE+3+GLUCURONIDE Search MORPHINE+3+GLUCURONIDE
5 CANCER PAIN 86 25% 5% 302 Search CANCER+PAIN Search CANCER+PAIN
6 O DESMETHYLTRAMADOL 86 96% 0% 26 Search O+DESMETHYLTRAMADOL Search O+DESMETHYLTRAMADOL
7 OXYCODONE 77 37% 3% 167 Search OXYCODONE Search OXYCODONE
8 OPIOID ROTATION 76 77% 1% 51 Search OPIOID+ROTATION Search OPIOID+ROTATION
9 METHADONE 65 17% 5% 352 Search METHADONE Search METHADONE
10 TAPENTADOL 62 67% 1% 56 Search TAPENTADOL Search TAPENTADOL

Key Words Plus



Rank Web of Science journal category Relevance score
(tfidf)
Class's shr.
of term's tot.
occurrences
Shr. of publ.
in class containing
term
Num. of
publ. in
class
1 MORPHINE 6 GLUCURONIDE 366 64% 6% 361
2 MORPHINE 3 GLUCURONIDE 256 76% 3% 181
3 O DESMETHYLTRAMADOL 151 88% 1% 72
4 ORAL MORPHINE 103 51% 2% 146
5 CANCER PAIN 95 20% 7% 438
6 TRANSDERMAL FENTANYL 79 41% 2% 149
7 MORPHINE 6 BETA GLUCURONIDE 77 82% 1% 45
8 CODEINE 76 27% 4% 237
9 ORAL METHADONE 72 66% 1% 67
10 A118G POLYMORPHISM 69 73% 1% 53

Journals

Reviews



Title Publ. year Cit. Active references % act. ref.
to same field
Use of opioid analgesics in the treatment of cancer pain: evidence-based recommendations from the EAPC 2012 143 68 69%
The effect of ondansetron on the efficacy of postoperative tramadol: a systematic review and meta-analysis of a drug interaction 2015 4 23 57%
Cellular signalling of non-synonymous single-nucleotide polymorphisms of the human mu-opioid receptor (OPRM1) 2015 4 104 36%
Clinical pharmacology of tramadol 2004 320 225 82%
The management of cancer-related breakthrough pain: Recommendations of a task group of the Science Committee of the Association for Palliative Medicine of Great Britain and Ireland 2009 114 36 81%
Prevalence of Breakthrough Cancer Pain: A Systematic Review and a Pooled Analysis of Published Literature 2014 10 49 59%
A Network Meta-Analysis of the Efficacy of Opioid Analgesics for the Management of Breakthrough Cancer Pain Episodes 2014 8 42 67%
Tramadol - A review of its use in perioperative pain 2000 225 89 79%
A review of morphine and morphine-6-glucuronide's pharmacokinetic-pharmacodynamic relationships in experimental and clinical pain 2015 1 85 65%
Pharmacotherapy for Breakthrough Cancer Pain 2012 20 34 100%

Address terms



Rank Address term Relevance score
(tfidf)
Class's shr.
of term's tot.
occurrences
Shr. of publ.
in class containing
term
Num. of
publ. in
class
1 PAIN RELIEF PALLIAT CARE UNIT 38 41% 1.1% 73
2 RUSH PAIN 14 100% 0.1% 7
3 CHAIR PALLIAT MED 10 47% 0.2% 16
4 ANESTHESIA INTENS CARE UNIT 8 19% 0.6% 40
5 CHRON PAIN DAY PROGRAM 6 100% 0.1% 4
6 MED AFFAIRS EUROPE AUSTRALIA 6 100% 0.1% 4
7 PAIN PALLIAT GRP 5 26% 0.3% 17
8 PAIN MED PALLIAT CARE 5 17% 0.4% 27
9 ANAESTHESIOL EMERGENCY MED 4 31% 0.2% 12
10 TOR VERGATA POLYCLIN 4 47% 0.1% 7

Related classes at same level (level 2)



Rank Relatedness score Related classes
1 0.0000037573 NONMEDICAL USE//PRESCRIPTION DRUG ABUSE//PRESCRIPTION OPIOIDS
2 0.0000016552 FIBROMYALGIA//FIBROMYALGIA SYNDROME//PAIN
3 0.0000013298 ANESTHESIOLOGY//REGIONAL ANESTHESIA AND PAIN MEDICINE//BUPIVACAINE
4 0.0000012808 XYLAZINE//VETERINARY ANAESTHESIA AND ANALGESIA//MEDETOMIDINE
5 0.0000012412 NOCICEPTIN//ORPHANIN FQ//NOCICEPTIN ORPHANIN FQ
6 0.0000011998 MDMA//ECSTASY//3 4 METHYLENEDIOXYMETHAMPHETAMINE
7 0.0000010618 HYPERALGESIA//NEUROPATHIC PAIN//ANTINOCICEPTION
8 0.0000007526 SPINAL CORD STIMULATION//COMPLEX REGIONAL PAIN SYNDROME//REFLEX SYMPATHETIC DYSTROPHY
9 0.0000007284 SUBSTANCE ABUSE//JOURNAL OF SUBSTANCE ABUSE TREATMENT//BUPRENORPHINE
10 0.0000007270 ANESTHESIOLOGY//PROPOFOL//DEXMEDETOMIDINE