Class information for:
Level 2: BRCA1//BRCA2//CHEK2

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
1348 7852 36.4 84%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 3)


ID, lev.
above		 Publications Label for level above
148 59739 BREAST CANCER//BREAST//BRCA1

Classes in level below (level 1)


ID, lev. below Publications Label for level below
172 3978 BRCA1//BRCA2//HEREDITARY BREAST CANCER
8375 1190 RNASEL//HEREDITARY PROSTATE CANCER//8Q24
11082 943 MULTIPLE PRIMARY MALIGNANCIES//MULTIPLE PRIMARY MALIGNANT NEOPLASMS//MULTIPLE PRIMARY NEOPLASMS
11575 906 CHEK2//PALB2//SERV CIRUGIA GEN ESPECIALIDADES
15526 637 CONTRALATERAL PROPHYLACTIC MASTECTOMY//BILATERAL BREAST CANCER//CONTRALATERAL BREAST CANCER
26999 198 ARLTS1//HERITABLE CANCER//FAMILIAL RISK

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of publ.
in class
1 BRCA1 Author keyword 1093 56% 17% 1318
2 BRCA2 Author keyword 675 58% 10% 782
3 CHEK2 Author keyword 139 82% 1% 80
4 HEREDITARY BREAST CANCER Author keyword 136 62% 2% 141
5 CANC GENET EPIDEMIOL Address 89 54% 1% 114
6 INT HEREDITARY CANC Address 79 51% 1% 110
7 PALB2 Author keyword 74 78% 1% 49
8 BRCA1 GENE Author keyword 66 65% 1% 63
9 FAMILIAL BREAST CANCER Author keyword 58 50% 1% 83
10 FAMILY CANC CLIN Address 58 48% 1% 88

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of publ.
in class		 LCSH search Wikipedia search
1 BRCA1 1093 56% 17% 1318 Search BRCA1 Search BRCA1
2 BRCA2 675 58% 10% 782 Search BRCA2 Search BRCA2
3 CHEK2 139 82% 1% 80 Search CHEK2 Search CHEK2
4 HEREDITARY BREAST CANCER 136 62% 2% 141 Search HEREDITARY+BREAST+CANCER Search HEREDITARY+BREAST+CANCER
5 PALB2 74 78% 1% 49 Search PALB2 Search PALB2
6 BRCA1 GENE 66 65% 1% 63 Search BRCA1+GENE Search BRCA1+GENE
7 FAMILIAL BREAST CANCER 58 50% 1% 83 Search FAMILIAL+BREAST+CANCER Search FAMILIAL+BREAST+CANCER
8 BILATERAL BREAST CANCER 53 63% 1% 53 Search BILATERAL+BREAST+CANCER Search BILATERAL+BREAST+CANCER
9 BARD1 52 74% 0% 39 Search BARD1 Search BARD1
10 CONTRALATERAL BREAST CANCER 44 67% 1% 40 Search CONTRALATERAL+BREAST+CANCER Search CONTRALATERAL+BREAST+CANCER

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 FOUNDER MUTATIONS 231 80% 2% 145
2 FAMILIAL BREAST 206 57% 3% 245
3 BRCA2 MUTATION CARRIERS 182 48% 4% 281
4 GERMLINE MUTATIONS 156 20% 9% 701
5 CONFER SUSCEPTIBILITY 154 61% 2% 165
6 EARLY ONSET BREAST 147 92% 1% 58
7 ASHKENAZI JEWISH WOMEN 138 85% 1% 73
8 8Q24 134 61% 2% 144
9 CHROMOSOME 8Q24 131 66% 2% 120
10 UNKNOWN CLINICAL SIGNIFICANCE 126 79% 1% 80

Journals


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 FAMILIAL CANCER 28 18% 2% 138
2 HEREDITARY CANCER IN CLINICAL PRACTICE 14 28% 1% 44

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
BRCA1 and BRCA2: different roles in a common pathway of genome protection 2012 176 109 50%
Cancer susceptibility and the functions of BRCA1 and BRCA2 2002 898 72 54%
BRCA1 and BRCA2: 1994 and beyond 2004 411 162 72%
The genetic epidemiology of prostate cancer and its clinical implications 2014 16 166 67%
Skin cancer risk in BRCA1/2 mutation carriers 2015 2 50 82%
Assessing Women at High Risk of Breast Cancer: A Review of Risk Assessment Models 2010 124 96 60%
Next-generation sequencing for hereditary breast and gynecologic cancer risk assessment 2015 2 35 71%
A Review of a Multifactorial Probability-Based Model for Classification of BRCA1 and BRCA2 Variants of Uncertain Significance (VUS) 2012 26 22 95%
Genetic Susceptibility to Triple-Negative Breast Cancer 2013 27 45 64%
BRCA1 and its toolbox for the maintenance of genome integrity 2010 179 120 36%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 CANC GENET EPIDEMIOL 89 54% 1.5% 114
2 INT HEREDITARY CANC 79 51% 1.4% 110
3 FAMILY CANC CLIN 58 48% 1.1% 88
4 UNIT MOL BASES GENET RISK GENET TESTING 57 65% 0.7% 54
5 ONCOGENET TEAM 46 74% 0.4% 34
6 SERV CIRUGIA GEN ESPECIALIDADES 45 83% 0.3% 25
7 FAMILIAL BREAST OVARIAN CANC 41 69% 0.4% 35
8 PROGRAM CANC GENET 38 37% 1.0% 82
9 ONTARIO CANC GENET NETWORK 34 59% 0.5% 38
10 CANC GENET TUMOR BIOL 31 76% 0.3% 22

Related classes at same level (level 2)


Rank Relatedness score Related classes
1 0.0000027686 CHROMATIN SUPRAORGANIZATION//ZNF703//NUCLEAR PHENOTYPES
2 0.0000024552 GENETIC TESTING//JOURNAL OF GENETIC COUNSELING//GENETIC COUNSELING
3 0.0000017212 FANCONI ANEMIA//ATAXIA TELANGIECTASIA//WERNER SYNDROME
4 0.0000011841 MAMMOGRAPHIC DENSITY//BREAST DENSITY//CANCER CAUSES & CONTROL
5 0.0000011159 STRUMA OVARII//OVARIAN CANCER//OVARIAN NEOPLASMS
6 0.0000010552 MICROSATELLITE INSTABILITY//LYNCH SYNDROME//HNPCC
7 0.0000009293 BREAST//DUCTAL CARCINOMA IN SITU//NIPPLE DISCHARGE
8 0.0000008489 GENETIC EPIDEMIOLOGY//GENOMIC SELECTION//BMC GENETICS
9 0.0000008085 BREAST CANCER//ACCELERATED PARTIAL BREAST IRRADIATION//PARTIAL BREAST IRRADIATION
10 0.0000007683 P73//MDM2//P53