Class information for:
Level 2: INTERLEUKIN 2//GRANZYME B//PERFORIN

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
1213 8727 34.7 70%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 3)


ID, lev.
above		 Publications Label for level above
198 48841 CELLULAR IMMUNOLOGY//THYMOSIN BETA 4//INTERLEUKIN 2

Classes in level below (level 1)


ID, lev. below Publications Label for level below
1219 2684 MHC AF//IMMUNODIAG//CARBOHYDRATE COMPONENT
1306 2627 INTERLEUKIN 2//LYMPHOKINE ACTIVATED KILLER CELLS//RECOMBINANT INTERLEUKIN 2
3970 1796 GRANZYME B//GRANZYME//PERFORIN
18650 475 MHC NONRESTRICTED CYTOTOXICITY//HISTAMINE DIHYDROCHLORIDE//BOWYER ONCOL
19142 453 OK 432//OK432//PROD LIFECYCLE MED INFORMAT
21360 363 BIOCHIM GEN GLYCOBIOL//3 3 DIOCTADECYLOXACARBOCYANINE PERCHLORATE//CONJUGATE FORMATION
22316 329 PIT CELLS//ACTIVATED NATURAL KILLER CELLS//A NK CELLS

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 INTERLEUKIN 2 Author keyword 117 17% 7% 609
2 GRANZYME B Author keyword 55 33% 2% 140
3 PERFORIN Author keyword 53 26% 2% 174
4 GRANZYME Author keyword 50 46% 1% 81
5 OK 432 Author keyword 45 38% 1% 95
6 LYMPHOKINE ACTIVATED KILLER CELLS Author keyword 29 36% 1% 64
7 LAK CELLS Author keyword 23 37% 1% 50
8 GRANZYME A Author keyword 19 49% 0% 28
9 RECOMBINANT INTERLEUKIN 2 Author keyword 18 47% 0% 29
10 GRANZYME M Author keyword 18 89% 0% 8

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 INTERLEUKIN 2 117 17% 7% 609 Search INTERLEUKIN+2 Search INTERLEUKIN+2
2 GRANZYME B 55 33% 2% 140 Search GRANZYME+B Search GRANZYME+B
3 PERFORIN 53 26% 2% 174 Search PERFORIN Search PERFORIN
4 GRANZYME 50 46% 1% 81 Search GRANZYME Search GRANZYME
5 OK 432 45 38% 1% 95 Search OK+432 Search OK+432
6 LYMPHOKINE ACTIVATED KILLER CELLS 29 36% 1% 64 Search LYMPHOKINE+ACTIVATED+KILLER+CELLS Search LYMPHOKINE+ACTIVATED+KILLER+CELLS
7 LAK CELLS 23 37% 1% 50 Search LAK+CELLS Search LAK+CELLS
8 GRANZYME A 19 49% 0% 28 Search GRANZYME+A Search GRANZYME+A
9 RECOMBINANT INTERLEUKIN 2 18 47% 0% 29 Search RECOMBINANT+INTERLEUKIN+2 Search RECOMBINANT+INTERLEUKIN+2
10 GRANZYME M 18 89% 0% 8 Search GRANZYME+M Search GRANZYME+M

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 RECOMBINANT INTERLEUKIN 2 275 33% 8% 675
2 ACTIVATED KILLER CELLS 263 34% 7% 629
3 LAK CELLS 87 49% 1% 128
4 RECOMBINANT HUMAN INTERLEUKIN 2 86 50% 1% 124
5 HIGH DOSE INTERLEUKIN 2 80 33% 2% 204
6 REPETITIVE WEEKLY CYCLES 80 84% 0% 43
7 PERFORIN 76 26% 3% 255
8 CONTINUOUS INFUSION INTERLEUKIN 2 69 66% 1% 65
9 PORE FORMING PROTEIN 61 42% 1% 112
10 TARGET CELLS 58 16% 4% 337

Journals


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 JOURNAL OF BIOLOGICAL RESPONSE MODIFIERS 13 16% 1% 76
2 NATURAL IMMUNITY AND CELL GROWTH REGULATION 12 26% 0% 40
3 BIOTHERAPY 5 13% 0% 38
4 NATURAL IMMUNITY 5 17% 0% 24
5 CANCER BIOTHERAPY 3 18% 0% 17

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
BIOLOGY OF NATURAL-KILLER CELLS 1989 2463 930 57%
Death by a thousand cuts: Granzyme pathways of programmed cell death 2008 179 202 74%
The ABCs of granule-mediated cytotoxicity: New weapons in the arsenal 2003 363 105 70%
Lymphocyte-mediated cytotoxicity 2002 554 256 48%
A quarter century of granzymes 2012 33 106 88%
INTERLEUKIN-2 TOXICITY 1991 352 69 75%
PERFORIN - STRUCTURE AND FUNCTION 1995 281 80 81%
Cytotoxic T lymphocytes: All roads lead to death 2002 365 99 57%
Functional significance of the perforin/granzyme cell death pathway 2002 472 123 43%
Are all granzymes cytotoxic in vivo? 2014 8 171 80%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 CANC CELL DEATH 14 64% 0.2% 14
2 JOHN CONNELL 12 86% 0.1% 6
3 CANC IMMUNOL PROGRAM 10 14% 0.7% 65
4 BIOCHIM GEN GLYCOBIOL 9 83% 0.1% 5
5 MET NIKOFF 7 44% 0.1% 12
6 PROD LIFECYCLE MED INFORMAT 6 100% 0.0% 4
7 RUPPERT 6 100% 0.0% 4
8 PROD S 5 54% 0.1% 7
9 BOWYER ONCOL 4 75% 0.0% 3
10 IMMUNODIAG 3 57% 0.0% 4

Related classes at same level (level 2)


Rank Relatedness score Related classes
1 0.0000033237 TUMOR DORMANCY//DORN VA MED//CONCOMITANT RESISTANCE
2 0.0000025543 P15E//IMMUNE SUPPRESSOR CELLS//IRX 2
3 0.0000021764 THYMUS//THYMIC NURSE CELLS//INTERLEUKIN 2 RECEPTOR
4 0.0000016286 HLA G//KIR//NKG2D
5 0.0000015986 JOURNAL OF THE RETICULOENDOTHELIAL SOCIETY//MANNOSE RECEPTOR//ENDO180
6 0.0000013722 IMMUNOTHERAPY//DENDRITIC CELLS//CANCER IMMUNOLOGY IMMUNOTHERAPY
7 0.0000012848 IMEXON//LEVAMISOLE//TYROSERLEUTIDE
8 0.0000011745 EOSINOPHIL CHEMOTACTIC FACTOR//LEUKOREGULIN//RYBINSK RESERVOIR
9 0.0000009681 JOURNAL OF INTERFERON RESEARCH//ISG15//JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
10 0.0000009065 UKRAIN//ANTITUMOR RESISTANCE//RE KAVETSKY EXPT PATHOL ONCOL RADIOBIOL