Class information for:
Level 1: CATHEPSIN K//PYCNODYSOSTOSIS//CATHEPSIN K INHIBITOR

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
9802 1054 38.1 81%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
1246 8504 CATHEPSIN B//CATHEPSIN K//CATHEPSIN D

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 CATHEPSIN K Author keyword 158 55% 19% 196
2 PYCNODYSOSTOSIS Author keyword 84 87% 4% 41
3 CATHEPSIN K INHIBITOR Author keyword 53 85% 3% 28
4 ONO 5334 Author keyword 23 100% 1% 10
5 ODANACATIB Author keyword 23 65% 2% 22
6 CATHEPSIN S INHIBITOR Author keyword 20 100% 1% 9
7 PYKNODYSOSTOSIS Author keyword 18 89% 1% 8
8 DISCOVERY COMPUTAT ANALYT STRUCT SCI Address 14 100% 1% 7
9 WORLD WIDE PHYS PROPERTIES Address 13 80% 1% 8
10 GENE EXP S PROT PURIFICAT Address 11 100% 1% 6

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 CATHEPSIN K 158 55% 19% 196 Search CATHEPSIN+K Search CATHEPSIN+K
2 PYCNODYSOSTOSIS 84 87% 4% 41 Search PYCNODYSOSTOSIS Search PYCNODYSOSTOSIS
3 CATHEPSIN K INHIBITOR 53 85% 3% 28 Search CATHEPSIN+K+INHIBITOR Search CATHEPSIN+K+INHIBITOR
4 ONO 5334 23 100% 1% 10 Search ONO+5334 Search ONO+5334
5 ODANACATIB 23 65% 2% 22 Search ODANACATIB Search ODANACATIB
6 CATHEPSIN S INHIBITOR 20 100% 1% 9 Search CATHEPSIN+S+INHIBITOR Search CATHEPSIN+S+INHIBITOR
7 PYKNODYSOSTOSIS 18 89% 1% 8 Search PYKNODYSOSTOSIS Search PYKNODYSOSTOSIS
8 CATHEPSIN K INHIBITORS 9 64% 1% 9 Search CATHEPSIN+K+INHIBITORS Search CATHEPSIN+K+INHIBITORS
9 CATHEPSIN S 9 12% 7% 69 Search CATHEPSIN+S Search CATHEPSIN+S
10 CTSK 7 67% 1% 6 Search CTSK Search CTSK

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 PYCNODYSOSTOSIS 125 79% 8% 81
2 ARYLAMINOETHYL AMIDES 72 100% 2% 23
3 PYKNODYSOSTOSIS 31 92% 1% 12
4 RESORBING COMPARTMENT 29 88% 1% 14
5 HUMAN OSTEOCLASTS 28 56% 3% 35
6 ODANACATIB 23 74% 2% 17
7 RESORBING AGENTS 17 79% 1% 11
8 CATHEPSIN K DEFICIENCY 15 68% 1% 13
9 LYSOSOMOTROPISM 15 88% 1% 7
10 CATHEPSIN K INHIBITOR 14 39% 3% 28

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Cathepsin K: its skeletal actions and role as a therapeutic target in osteoporosis 2011 56 80 81%
Cathepsin K inhibitors for osteoporosis and potential off-target effects 2009 53 124 72%
Clinical and radiographic maxillofacial features of pycnodysostosis 2014 2 13 100%
Cathepsin K: a unique collagenolytic cysteine peptidase 2013 14 123 60%
Cathepsin S inhibitors: 2004-2010 2011 19 54 76%
The role of cathepsins in osteoporosis and arthritis: Rationale for the design of new therapeutics 2005 146 142 39%
Clinical and animal research findings in pycnodysostosis and gene mutations of cathepsin K from 1996 to 2011 2011 16 85 79%
Cathepsins and cystatin C in atherosclerosis and obesity 2010 34 55 44%
Cathepsin cysteine proteases in cardiovascular disease 2007 122 91 34%
Recent Advances in the Design of Cathepsin S Inhibitors 2010 18 48 67%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 DISCOVERY COMPUTAT ANALYT STRUCT SCI 14 100% 0.7% 7
2 WORLD WIDE PHYS PROPERTIES 13 80% 0.8% 8
3 GENE EXP S PROT PURIFICAT 11 100% 0.6% 6
4 CLIN DEV PLANNING 5 63% 0.5% 5
5 EXPT ORAL BIOL GRP 4 75% 0.3% 3
6 SECT OXIDAT ST S INFLAMMAT 3 100% 0.3% 3
7 CLIN CELL BIOL KCB 3 50% 0.4% 4
8 VEJLE LILLEBAELT HOSP 3 60% 0.3% 3
9 PHYS STRUCT CHEM 2 18% 1.0% 11
10 BONE CARTILAGE BIOL 2 15% 1.1% 12

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000228799 CATHEPSIN B//CATHEPSIN L//CATHEPSIN X
2 0.0000129734 TARTRATE RESISTANT ACID PHOSPHATASE//SPECIAL HEMATOL//TARTRATE RESISTANT
3 0.0000097896 RANKL//OSTEOCLAST//OSTEOCLASTOGENESIS
4 0.0000094035 OSTEOPETROSIS//MALIGNANT INFANTILE OSTEOPETROSIS//TCIRG1
5 0.0000082060 TUMOR TISSUE PROGRESSION//FIBROBLAST COLLAGENASE//CARRAGEENAN GRANULOMA
6 0.0000048036 TERIPARATIDE//PTH//REG BONE
7 0.0000047900 ALLIED MED SCI SUMA KU//MED FUKUSHIMA KU//TARUMI KU
8 0.0000047775 DRYNARIA FORTUNEI//DRYNARIAE RHIZOMA//DRYNARIA QUERCIFOLIA
9 0.0000042186 POSITIVE BONE BALANCE//PROSTAGLANDIN ESTRADIOL PGE2//ENDOCRINOL METAB MC1850
10 0.0000040645 GROWTH HORMONE BIOL//IN SITU SETTING CEMENT//POLYD L LACTIDE COATING