Class information for:
Level 1: CRUZAIN//PLASMEPSIN//CRUZIPAIN

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
9727 1061 40.5 83%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
131 22844 TRYPANOSOMA CRUZI//CHAGAS DISEASE//TRYPANOSOMA EVANSI

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 CRUZAIN Author keyword 62 90% 3% 27
2 PLASMEPSIN Author keyword 62 80% 4% 39
3 CRUZIPAIN Author keyword 41 56% 5% 50
4 FALCIPAIN Author keyword 38 78% 2% 25
5 FALCIPAIN 2 Author keyword 38 78% 2% 25
6 PLASMEPSIN II Author keyword 28 81% 2% 17
7 FALCIPAIN 2 INHIBITORS Author keyword 27 92% 1% 11
8 CHAGASIN Author keyword 15 82% 1% 9
9 PLASMEPSINS Author keyword 15 77% 1% 10
10 RHODESAIN Author keyword 11 69% 1% 9

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 CRUZAIN 62 90% 3% 27 Search CRUZAIN Search CRUZAIN
2 PLASMEPSIN 62 80% 4% 39 Search PLASMEPSIN Search PLASMEPSIN
3 CRUZIPAIN 41 56% 5% 50 Search CRUZIPAIN Search CRUZIPAIN
4 FALCIPAIN 38 78% 2% 25 Search FALCIPAIN Search FALCIPAIN
5 FALCIPAIN 2 38 78% 2% 25 Search FALCIPAIN+2 Search FALCIPAIN+2
6 PLASMEPSIN II 28 81% 2% 17 Search PLASMEPSIN+II Search PLASMEPSIN+II
7 FALCIPAIN 2 INHIBITORS 27 92% 1% 11 Search FALCIPAIN+2+INHIBITORS Search FALCIPAIN+2+INHIBITORS
8 CHAGASIN 15 82% 1% 9 Search CHAGASIN Search CHAGASIN
9 PLASMEPSINS 15 77% 1% 10 Search PLASMEPSINS Search PLASMEPSINS
10 RHODESAIN 11 69% 1% 9 Search RHODESAIN Search RHODESAIN

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 RECOMBINANT FALCIPAIN 2 126 95% 4% 41
2 HEMOGLOBIN DEGRADATION 68 49% 10% 102
3 CYSTEINE PROTEASE FALCIPAIN 2 65 93% 2% 25
4 FOOD VACUOLE 42 57% 5% 50
5 GP57 51 33 83% 2% 19
6 HEMOGLOBINASE 24 57% 3% 29
7 FALCIPARUM FOOD VACUOLE 23 74% 2% 17
8 CYSTEINE PROTEASE INHIBITORS 22 28% 6% 68
9 PLASMEPSIN II 20 39% 4% 41
10 PROTEINASE CRUZIPAIN 19 80% 1% 12

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Falcipain Inhibition as a Promising Antimalarial Target 2012 18 109 72%
Hemoglobin degradation 2005 94 65 77%
Falcipain-2 Inhibitors 2010 45 114 46%
Falcipain inhibitors as potential therapeutics for resistant strains of malaria: a patent review 2013 4 40 88%
The peptidases of Trypanosoma cruzi: Digestive enzymes, virulence factors, and mediators of autophagy and programmed cell death 2012 25 138 43%
Falcipains, Plasmodium falciparum Cysteine Proteases as Key Drug Targets Against Malaria 2011 30 122 48%
Plasmepsins as potential targets for new antimalarial therapy 2006 92 138 59%
Recent Advances in Plasmepsin Medicinal Chemistry and Implications for Future Antimalarial Drug Discovery Efforts 2012 11 57 70%
Cysteine proteases of parasitic organisms 2002 427 97 29%
Plasmodium falciparum neutral aminopeptidases: new targets for anti-malarials 2010 23 55 58%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 MALARIA BIOL 7 35% 1.5% 16
2 SANDLER BASIC PARASIT DIS 6 24% 2.0% 21
3 BIOL MOL DOENCAS ENDEM 4 21% 1.8% 19
4 ESTUDIO PROTEINAS 4 67% 0.4% 4
5 BIOQUIM PROTEASES 3 50% 0.5% 5
6 CELLULAR MOL PHARMACOL MED 3 100% 0.3% 3
7 CIENCIA TECNOL DR CESAR MILSTEIN ICT MILST 3 100% 0.3% 3
8 DIPARTMENTO SCI BIOCHIM A ROSSI FANELLI 3 100% 0.3% 3
9 TECNOL FARMACOS FARMANGUINHOS 3 19% 1.2% 13
10 BIOL CELULAR PARASITOS 3 60% 0.3% 3

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000149081 BETA HEMATIN//HEMOZOIN//4 AMINOQUINOLINE
2 0.0000109363 CATHEPSIN B//CATHEPSIN L//CATHEPSIN X
3 0.0000088869 METACASPASE//DYSKINETOPLASTIDY//APOPTOSIS LIKE PROGRAMMED CELL DEATH
4 0.0000083385 LIPOPHOSPHOGLYCAN//LEISHMANIA//GP63
5 0.0000083284 NEW PERMEABILITY PATHWAYS//CHOLINE ANALOGUES//PFHT
6 0.0000078311 TRANS SIALIDASE//METACYCLIC TRYPOMASTIGOTES//PREDIO INTI
7 0.0000062684 NECATOR AMERICANUS//HOOKWORM//HAEMONCHUS CONTORTUS
8 0.0000060356 NITRO RADICAL ANION//NIFURTIMOX//BIOELE OCHEM
9 0.0000059417 CRYPTOBIA SALMOSITICA//PHYTOMONAS//TRYPANOPLASMA BORRELI
10 0.0000051034 PFEMP1//UNITE BIOL INTERACT HOTE PARASITE//CYTOADHERENCE