Class information for:
Level 1: DIRECTED EVOLUTION//DNA SHUFFLING//EPPCR

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
9662 1067 42.1 83%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
2410 3719 HYDANTOINASE//D HYDANTOINASE//DIRECTED EVOLUTION

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 DIRECTED EVOLUTION Author keyword 55 21% 22% 233
2 DNA SHUFFLING Author keyword 22 35% 5% 52
3 EPPCR Author keyword 9 83% 0% 5
4 RANDOM MUTAGENESIS Author keyword 7 14% 4% 44
5 CHEM CHEM ENGN 21041 Address 6 80% 0% 4
6 MUTATIONAL ADDITIVITY Author keyword 6 71% 0% 5
7 DIRECTED ENZYME EVOLUTION Author keyword 5 60% 1% 6
8 SATURATION MUTAGENESIS Author keyword 5 21% 2% 22
9 FENSKE 112 Address 4 67% 0% 4
10 INCREMENTAL TRUNCATION Author keyword 4 56% 0% 5

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 DIRECTED EVOLUTION 55 21% 22% 233 Search DIRECTED+EVOLUTION Search DIRECTED+EVOLUTION
2 DNA SHUFFLING 22 35% 5% 52 Search DNA+SHUFFLING Search DNA+SHUFFLING
3 EPPCR 9 83% 0% 5 Search EPPCR Search EPPCR
4 RANDOM MUTAGENESIS 7 14% 4% 44 Search RANDOM+MUTAGENESIS Search RANDOM+MUTAGENESIS
5 MUTATIONAL ADDITIVITY 6 71% 0% 5 Search MUTATIONAL+ADDITIVITY Search MUTATIONAL+ADDITIVITY
6 DIRECTED ENZYME EVOLUTION 5 60% 1% 6 Search DIRECTED+ENZYME+EVOLUTION Search DIRECTED+ENZYME+EVOLUTION
7 SATURATION MUTAGENESIS 5 21% 2% 22 Search SATURATION+MUTAGENESIS Search SATURATION+MUTAGENESIS
8 INCREMENTAL TRUNCATION 4 56% 0% 5 Search INCREMENTAL+TRUNCATION Search INCREMENTAL+TRUNCATION
9 ITCHY 3 57% 0% 4 Search ITCHY Search ITCHY
10 ERROR PRONE PCR 3 17% 2% 18 Search ERROR+PRONE+PCR Search ERROR+PRONE+PCR

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 IN VITRO RECOMBINATION 75 57% 8% 90
2 DIRECTED EVOLUTION 45 12% 33% 349
3 ITERATIVE SATURATION MUTAGENESIS 30 54% 4% 38
4 CHROMOGENIC SUBSTRATE ARRAYS 26 80% 1% 16
5 GENETIC SELECTION SYSTEM 18 89% 1% 8
6 SHUFFLING METHOD 17 100% 1% 8
7 RANDOM MUTAGENESIS 15 20% 6% 68
8 SATURATION MUTAGENESIS 14 26% 4% 48
9 ENANTIOSELECTIVE ENZYMES 13 62% 1% 13
10 ENZYME FINGERPRINTS 12 75% 1% 9

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Addressing the numbers problem in directed evolution 2008 127 96 58%
Strategies for the discovery and engineering of enzymes for biocatalysis 2013 36 47 51%
Advances in laboratory evolution of enzymes 2008 133 74 49%
Directed evolution drives the next generation of biocatalysts 2009 254 85 38%
Status of protein engineering for biocatalysts: how to design an industrially useful biocatalyst 2011 68 41 51%
Novel methods for directed evolution of enzymes: quality, not quantity 2004 125 47 66%
Laboratory Evolution of Stereoselective Enzymes: A Prolific Source of Catalysts for Asymmetric Reactions 2011 112 282 33%
Synthetic biology for the directed evolution of protein biocatalysts: navigating sequence space intelligently 2015 3 1134 16%
Exploring protein fitness landscapes by directed evolution 2009 203 107 36%
Directed evolution of enantioselective enzymes: Iterative cycles of CASTing for probing protein-sequence space 2006 146 75 43%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 CHEM CHEM ENGN 21041 6 80% 0.4% 4
2 FENSKE 112 4 67% 0.4% 4
3 BIOTECHNOL ENZYME CATALYSIS 3 14% 2.1% 22
4 ASCD 2 67% 0.2% 2
5 TECH CHEM BIOTECHNOL 2 19% 0.9% 10
6 CHEM CHEM ENGN 210 41 2 21% 0.7% 8
7 WARTIK 414 2 21% 0.7% 8
8 CHINA UK HUST R CROP GENET ENGN GENOM JOINT 1 50% 0.2% 2
9 UNITE CHIM ORGANURA 2128 1 100% 0.2% 2
10 MOL ENZYMTECHNOL 1 12% 0.8% 9

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000137068 COMPUTATIONAL PROTEIN DESIGN//DEAD END ELIMINATION//COMPUTATIONAL ENZYME DESIGN
2 0.0000125388 MEGAPRIMER//OVERLAP EXTENSION//MULTIPLE SITE DIRECTED MUTAGENESIS
3 0.0000094913 GENOME SHUFFLING//VITICULTURE WINE//BIOCHEM PHARMACEUT ENGN
4 0.0000094276 CELL FREE PROTEIN SYNTHESIS//RIBOSOME DISPLAY//S30 EXTRACT
5 0.0000085164 NAT MED IMMUNAL ENGN//BIOCHIRAL//EXCITON COUPLED CIRCULAR DICHROISM
6 0.0000085063 STAPHYLOCOCCAL NUCLEASE//THERMODYNAMIC MOLECULAR SWITCH//PROTEIN THERMOSTABILITY
7 0.0000085063 OMEGA TRANSAMINASE//DYNAMIC KINETIC RESOLUTION//TRANSAMINASE
8 0.0000076444 LIPASE//ALKALINE LIPASE//LIPASE PRODUCTION
9 0.0000075488 BIOCATALYTIC PROMISCUITY//4 OXALOCROTONATE TAUTOMERASE//TAUTOMERASE SUPERFAMILY
10 0.0000072876 BAEYER VILLIGER OXIDATION//BAEYER VILLIGER MONOOXYGENASE//CYCLOHEXANONE MONOOXYGENASE