Class information for:
Level 1: EPOTHILONES//EPOTHILONE//IXABEPILONE

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
8975 1132 42.0 80%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
299 17980 ANNONACEOUS ACETOGENINS//PRINS CYCLIZATION//ACETOGENINS

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 EPOTHILONES Author keyword 140 71% 10% 113
2 EPOTHILONE Author keyword 104 69% 8% 89
3 IXABEPILONE Author keyword 71 61% 7% 76
4 DISCODERMOLIDE Author keyword 65 84% 3% 36
5 ELEUTHEROBIN Author keyword 53 95% 2% 18
6 PELORUSIDE A Author keyword 53 95% 2% 18
7 LAULIMALIDE Author keyword 42 76% 3% 29
8 PATUPILONE Author keyword 40 76% 2% 28
9 SAGOPILONE Author keyword 26 80% 1% 16
10 PELORUSIDE Author keyword 23 86% 1% 12

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 EPOTHILONES 140 71% 10% 113 Search EPOTHILONES Search EPOTHILONES
2 EPOTHILONE 104 69% 8% 89 Search EPOTHILONE Search EPOTHILONE
3 IXABEPILONE 71 61% 7% 76 Search IXABEPILONE Search IXABEPILONE
4 DISCODERMOLIDE 65 84% 3% 36 Search DISCODERMOLIDE Search DISCODERMOLIDE
5 ELEUTHEROBIN 53 95% 2% 18 Search ELEUTHEROBIN Search ELEUTHEROBIN
6 PELORUSIDE A 53 95% 2% 18 Search PELORUSIDE+A Search PELORUSIDE+A
7 LAULIMALIDE 42 76% 3% 29 Search LAULIMALIDE Search LAULIMALIDE
8 PATUPILONE 40 76% 2% 28 Search PATUPILONE Search PATUPILONE
9 SAGOPILONE 26 80% 1% 16 Search SAGOPILONE Search SAGOPILONE
10 PELORUSIDE 23 86% 1% 12 Search PELORUSIDE Search PELORUSIDE

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 MICROTUBULE STABILIZING AGENTS 243 62% 22% 249
2 DESOXYEPOTHILONE B 164 89% 7% 74
3 MARINE SPONGE ORIGIN 135 97% 3% 37
4 DISCODERMOLIDE 131 65% 11% 123
5 OLEFIN METATHESIS APPROACH 122 95% 4% 40
6 BMS 247550 94 76% 6% 65
7 TAXOID SITE 84 78% 5% 56
8 EPOTHILONE B 68 64% 6% 67
9 DAILY SCHEDULE 65 90% 2% 28
10 MICROTUBULE STABILIZING MACROLIDE 64 88% 3% 30

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Discovery of Ixabepilone 2009 43 13 85%
Recent progress with microtubule stabilizers: new compounds, binding modes and cellular activities 2014 11 158 49%
Epothilones as lead structures for the synthesis-based discovery of new chemotypes for microtubule stabilization 2008 48 21 67%
The structure activity relationship of discodermolide analogues 2008 22 42 100%
Novel Drugs Targeting Microtubules: the Role of Epothilones 2012 15 71 59%
Epothilones and related structures - a new class of microtubule inhibitors with potent in vivo antitumor activity 2000 152 44 80%
Anticancer drugs from nature - natural products as a unique source of new microtubule-stabilizing agents 2007 107 320 50%
Epothilones: tubulin polymerization as a novel target for prostate cancer therapy 2009 19 40 75%
Recent developments in the chemical biology of epothilones 2005 62 94 81%
Epothilones: a noel class of microtubule-stabilizing drugs for the treatment of cancer 2008 20 69 90%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 PRECLIN PHARMACOL CORE IL 8 62% 0.7% 8
2 BIODISCOVERY 7 23% 2.2% 25
3 ANALYT PHARMACOL CORE IL 6 71% 0.4% 5
4 ONCOL DA 4 75% 0.3% 3
5 TA ONCOL 3 43% 0.5% 6
6 GLOBAL MED DEV ONCOL 3 100% 0.3% 3
7 ABT NAT STOFFCHEM 2 31% 0.4% 5
8 BIODISCOVERY CHEM PHYS SCI 1 100% 0.2% 2
9 ABT NATURSTOFFCHEM 1 23% 0.4% 5
10 ECCELLENZA CISI 1 18% 0.5% 6

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000102550 ERIBULIN MESYLATE//ERIBULIN//HALICHONDRIN B
2 0.0000097392 MYXOBACTERIA//TUBULYSIN//TUBULYSINS
3 0.0000082029 DOLASTATIN 10//DIDEMNIN B//TZT 1027
4 0.0000081248 HEMATOL ONCOLWINSHIP CANC//MICROTUBULE ACTIVE DRUGS//PHARMACOLRAMMELKAMP EDUC
5 0.0000080144 COMBRETASTATIN//COMBRETASTATIN A 4//COMBRETASTATINS
6 0.0000070909 TUBULIN ISOTYPES//TYROSINATION//DETYROSINATION
7 0.0000065098 TAXACEAE//TAXOIDS//TAXOID
8 0.0000060177 METASTATIC BREAST CANCER//VINORELBINE//DOCETAXEL
9 0.0000059175 NON CROSS LINKED POLYSTYRENE//TITANIUM ENOLATES//THIAZOLIDINETHIONES
10 0.0000053131 APLYRONINE A//THEONELLA SWINHOEI//BISTRAMIDE A