Class information for:
Level 1: METFORMIN//LACTIC ACIDOSIS//METFORMIN ASSOCIATED LACTIC ACIDOSIS

Basic class information

ID Publications Average number
of references
Avg. shr. active
ref. in WoS
8937 1135 35.3 69%



Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)



ID, lev.
above
Publications Label for level above
1662 6318 METFORMIN//ACARBOSE//GLIMEPIRIDE

Terms with highest relevance score



Rank Term Type of term Relevance score
(tfidf)
Class's shr.
of term's tot.
occurrences
Shr. of publ.
in class containing
term
Num. of
publ. in
class
1 METFORMIN Author keyword 84 16% 44% 496
2 LACTIC ACIDOSIS Author keyword 19 16% 9% 105
3 METFORMIN ASSOCIATED LACTIC ACIDOSIS Author keyword 8 100% 0% 5
4 BIGUANIDES Author keyword 6 21% 2% 23
5 BIGUANIDE Author keyword 4 20% 1% 17
6 EXTENDED RELEASE METFORMIN Author keyword 3 100% 0% 3
7 NAZL INFORMAZ TOSSICOL Address 3 100% 0% 3
8 BOWEL UPTAKE Author keyword 3 60% 0% 3
9 CAS 657 24 9 Author keyword 2 67% 0% 2
10 ORAL ANTI DIABETIC THERAPY Author keyword 2 67% 0% 2

Web of Science journal categories

Author Key Words



Rank Web of Science journal category Relevance score
(tfidf)
Class's shr.
of term's tot.
occurrences
Shr. of publ.
in class containing
term
Num. of
publ. in
class
LCSH search Wikipedia search
1 METFORMIN 84 16% 44% 496 Search METFORMIN Search METFORMIN
2 LACTIC ACIDOSIS 19 16% 9% 105 Search LACTIC+ACIDOSIS Search LACTIC+ACIDOSIS
3 METFORMIN ASSOCIATED LACTIC ACIDOSIS 8 100% 0% 5 Search METFORMIN+ASSOCIATED+LACTIC+ACIDOSIS Search METFORMIN+ASSOCIATED+LACTIC+ACIDOSIS
4 BIGUANIDES 6 21% 2% 23 Search BIGUANIDES Search BIGUANIDES
5 BIGUANIDE 4 20% 1% 17 Search BIGUANIDE Search BIGUANIDE
6 EXTENDED RELEASE METFORMIN 3 100% 0% 3 Search EXTENDED+RELEASE+METFORMIN Search EXTENDED+RELEASE+METFORMIN
7 BOWEL UPTAKE 3 60% 0% 3 Search BOWEL+UPTAKE Search BOWEL+UPTAKE
8 CAS 657 24 9 2 67% 0% 2 Search CAS+657+24+9 Search CAS+657+24+9
9 ORAL ANTI DIABETIC THERAPY 2 67% 0% 2 Search ORAL+ANTI+DIABETIC+THERAPY Search ORAL+ANTI+DIABETIC+THERAPY
10 PHENFORMIN 2 20% 1% 9 Search PHENFORMIN Search PHENFORMIN

Key Words Plus



Rank Web of Science journal category Relevance score
(tfidf)
Class's shr.
of term's tot.
occurrences
Shr. of publ.
in class containing
term
Num. of
publ. in
class
1 BIGUANIDES 33 50% 4% 47
2 CONTRAINDICATIONS 10 24% 3% 36
3 INDUCED LACTIC ACIDOSIS 7 36% 1% 15
4 INTRACELLULAR POOL 6 26% 2% 18
5 PHENFORMIN 5 30% 1% 13
6 LOW DOSE METFORMIN 4 75% 0% 3
7 OBESE NONDIABETIC SUBJECTS 4 75% 0% 3
8 INSULIN RECEPTOR BINDING 3 35% 1% 8
9 FREMANTLE 3 100% 0% 3
10 PROLONGED HEMODIALYSIS 2 67% 0% 2

Journals

Reviews



Title Publ. year Cit. Active references % act. ref.
to same field
Drug therapy - Metformin 1996 980 52 65%
Use of Metformin in the Setting of Mild-to-Moderate Renal Insufficiency 2011 89 43 65%
Metformin: An update 2002 444 93 52%
Clinical Pharmacokinetics of Metformin 2011 158 80 35%
Metformin and other antidiabetic agents in renal failure patients 2015 6 110 29%
Metformin in Patients With Type 2 Diabetes and Kidney Disease A Systematic Review 2014 12 66 86%
Acute Metformin Overdose: Examining Serum pH, Lactate Level, and Metformin Concentrations in Survivors Versus Nonsurvivors: A Systematic Review of the Literature 2009 35 6 83%
Metformin and lactic acidosis: cause or coincidence? A review of case reports 2004 95 31 94%
Metformin revisited: A critical review of the benefit-risk balance in at-risk patients with type 2 diabetes 2013 36 83 40%
Metformin-Associated Lactic Acidosis 2015 1 38 74%

Address terms



Rank Address term Relevance score
(tfidf)
Class's shr.
of term's tot.
occurrences
Shr. of publ.
in class containing
term
Num. of
publ.
in class
1 NAZL INFORMAZ TOSSICOL 3 100% 0.3% 3
2 COMPARAT BIOCHEM PHYSIOL 2 50% 0.3% 3
3 DINO FERRARIDIPARTIMENTO SCI NEUROL 1 50% 0.2% 2
4 INT PHARMACOL SUPPORT 1 100% 0.2% 2
5 LYONNAISE IND PHARMACEUT 1 100% 0.2% 2
6 METAB CLIN DESIGN EVALUAT 1 100% 0.2% 2
7 ANESTHESIA INTENS 1 50% 0.1% 1
8 ARRHYTHMIA MANAGEMENT CLIN OUTCOMES 1 50% 0.1% 1
9 ATENC PRIMARIA LA MINA 1 50% 0.1% 1
10 BEIJING CHAOYANG HOSP AFFILIATED 1 50% 0.1% 1

Related classes at same level (level 1)



Rank Relatedness score Related classes
1 0.0000138728 GLIMEPIRIDE//JTT 608//SECONDARY FAILURE
2 0.0000134366 METFORMIN HYDROCHLORIDE//PIOGLITAZONE HYDROCHLORIDE//ROSIGLITAZONE MALEATE
3 0.0000110810 NATEGLINIDE//KAD 1229//REPAGLINIDE
4 0.0000108224 PIOGLITAZONE//ROSIGLITAZONE//THIAZOLIDINEDIONES
5 0.0000098774 TROGLITAZONE//JTT 501//CAS 97322 87 7
6 0.0000096658 TYPE B LACTIC ACIDOSIS//SODIUM DICHLOROACETATE DCA//ACID BASE EQUILIBRIUM METABOLIC ACIDOSIS
7 0.0000089392 INSULIN GLARGINE//INSULIN DETEMIR//BIPHASIC INSULIN ASPART 30
8 0.0000083074 ACARBOSE//ALPHA GLUCOSIDASE INHIBITOR//MIGLITOL
9 0.0000080093 AMPK//AMP ACTIVATED PROTEIN KINASE//AICAR
10 0.0000079733 GLICLAZIDE//INTERNAL MED DIABETOL CLIN PHARMACOL//DRUG QUAL CONTROL PHARMACOVIGILANC