Class information for:
Level 1: MCL 1//ABT 737//BCL 2 FAMILY

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
864 2915 50.7 95%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
169 21476 TRAIL//SURVIVIN//BCL 2

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 MCL 1 Author keyword 84 35% 7% 192
2 ABT 737 Author keyword 52 56% 2% 63
3 BCL 2 FAMILY Author keyword 46 28% 5% 143
4 BH3 ONLY Author keyword 45 69% 1% 38
5 BH3 ONLY PROTEINS Author keyword 37 57% 2% 44
6 BH3 Author keyword 33 58% 1% 38
7 BH3 MIMETICS Author keyword 30 64% 1% 29
8 OBATOCLAX Author keyword 29 66% 1% 27
9 BH3 DOMAIN Author keyword 29 58% 1% 33
10 BAK Author keyword 27 28% 3% 83

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 MCL 1 84 35% 7% 192 Search MCL+1 Search MCL+1
2 ABT 737 52 56% 2% 63 Search ABT+737 Search ABT+737
3 BCL 2 FAMILY 46 28% 5% 143 Search BCL+2+FAMILY Search BCL+2+FAMILY
4 BH3 ONLY 45 69% 1% 38 Search BH3+ONLY Search BH3+ONLY
5 BH3 ONLY PROTEINS 37 57% 2% 44 Search BH3+ONLY+PROTEINS Search BH3+ONLY+PROTEINS
6 BH3 33 58% 1% 38 Search BH3 Search BH3
7 BH3 MIMETICS 30 64% 1% 29 Search BH3+MIMETICS Search BH3+MIMETICS
8 OBATOCLAX 29 66% 1% 27 Search OBATOCLAX Search OBATOCLAX
9 BH3 DOMAIN 29 58% 1% 33 Search BH3+DOMAIN Search BH3+DOMAIN
10 BAK 27 28% 3% 83 Search BAK Search BAK

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 BH3 ONLY PROTEINS 317 52% 15% 431
2 BH3 MIMETIC ABT 737 250 72% 7% 196
3 BH3 DOMAINS 231 74% 6% 169
4 BH3 DOMAIN 130 49% 7% 193
5 X L 106 53% 5% 142
6 BCL XL 83 20% 13% 382
7 MCL 1 77 32% 7% 197
8 BCL 2 FAMILY MEMBERS 75 28% 8% 226
9 BAX 69 14% 16% 461
10 CYTOCHROME C RELEASE 66 11% 19% 557

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy 2014 141 212 72%
Small molecule Mcl-1 inhibitors for the treatment of cancer 2015 12 84 85%
The BCL-2 protein family: opposing activities that mediate cell death 2008 1715 161 68%
The Bcl-2 apoptotic switch in cancer development and therapy 2007 856 133 60%
Mitochondria in Apoptosis: Bcl-2 Family Members and Mitochondrial Dynamics 2011 346 114 49%
Many players in BCL-2 family affairs 2014 31 94 72%
Building blocks of the apoptotic pore: how Bax and Bak are activated and oligomerize during apoptosis 2014 21 118 89%
The BCL-2 Family Reunion 2010 481 87 37%
The pathophysiology of mitochondrial cell death 2004 1715 38 39%
How do BCL-2 proteins induce mitochondrial outer membrane permeabilization? 2008 444 51 65%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 TEAM CELL SURVIVAL TUMOR ESC E BREAST CANC 8 12 86% 0.2% 6
2 MOL GENET CANC 11 34% 0.9% 27
3 UMR601 8 70% 0.2% 7
4 PROGRAM CANC CHEM BIOL 4 28% 0.4% 13
5 SERONO PHARMACEUT 4 32% 0.4% 11
6 PLATEFORME IMPACT 4 75% 0.1% 3
7 HOWARD HUGHES MED PATHOL 3 37% 0.2% 7
8 LINDE PROGRAM CANC CHEM BIOL 3 45% 0.2% 5
9 BIOGENOUEST RECH THER EUT 2 67% 0.1% 2
10 BIOL INNOVAT THER EUT LOCALLY AGG S CANC UNI 2 67% 0.1% 2

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000189700 TAT BH4//MOL CELLULAR SIGNALING//BIOEMERGENCES IBISA
2 0.0000141549 BCL 2//BCL 2 PROTEIN//BCL X
3 0.0000122825 MGDC//VERRUCARIN A//RADIAT TUMOR PHYSIOL
4 0.0000115234 BCL2L12//BCL2 FAMILY//G P ANICOLAOU ONCOL
5 0.0000114737 BIKDD//MITOCHONDRIAL CYTOCHROME C RELEASE//BAX OVEREXPRESSION
6 0.0000086138 APAF 1//CASPASE 2//RAIDD
7 0.0000084874 BNIP3//BCH DOMAIN//HGTD P
8 0.0000078135 PLATELET APOPTOSIS//COATED PLATELET//STUDY HUMAN OPERATOR PERFORMANCE
9 0.0000071146 APOPTOSIS INDUCING FACTOR//AIF//AMID
10 0.0000066926 HEMATOL ONCOLWINSHIP CANC//MICROTUBULE ACTIVE DRUGS//PHARMACOLRAMMELKAMP EDUC