Class information for:
Level 1: SCLEROSTIN//SOST//LRP5

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
7900 1238 47.6 90%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
1396 7607 GENET CELL BIOL SECTCHUO KU//WNT//GENET CELL BIOL SECT

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 SCLEROSTIN Author keyword 194 64% 15% 190
2 SOST Author keyword 45 68% 3% 40
3 LRP5 Author keyword 39 48% 5% 59
4 SCLEROSTEOSIS Author keyword 33 83% 2% 19
5 SCLEROSTIN ANTIBODY Author keyword 21 71% 1% 17
6 VAN BUCHEM DISEASE Author keyword 15 77% 1% 10
7 OSTEOPOROSIS PSEUDOGLIOMA SYNDROME Author keyword 12 86% 0% 6
8 HIGH BONE MASS Author keyword 10 54% 1% 13
9 BLOSOZUMAB Author keyword 9 83% 0% 5
10 ROMOSOZUMAB Author keyword 8 70% 1% 7

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 SCLEROSTIN 194 64% 15% 190 Search SCLEROSTIN Search SCLEROSTIN
2 SOST 45 68% 3% 40 Search SOST Search SOST
3 LRP5 39 48% 5% 59 Search LRP5 Search LRP5
4 SCLEROSTEOSIS 33 83% 2% 19 Search SCLEROSTEOSIS Search SCLEROSTEOSIS
5 SCLEROSTIN ANTIBODY 21 71% 1% 17 Search SCLEROSTIN+ANTIBODY Search SCLEROSTIN+ANTIBODY
6 VAN BUCHEM DISEASE 15 77% 1% 10 Search VAN+BUCHEM+DISEASE Search VAN+BUCHEM+DISEASE
7 OSTEOPOROSIS PSEUDOGLIOMA SYNDROME 12 86% 0% 6 Search OSTEOPOROSIS+PSEUDOGLIOMA+SYNDROME Search OSTEOPOROSIS+PSEUDOGLIOMA+SYNDROME
8 HIGH BONE MASS 10 54% 1% 13 Search HIGH+BONE+MASS Search HIGH+BONE+MASS
9 BLOSOZUMAB 9 83% 0% 5 Search BLOSOZUMAB Search BLOSOZUMAB
10 ROMOSOZUMAB 8 70% 1% 7 Search ROMOSOZUMAB Search ROMOSOZUMAB

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 VAN BUCHEM DISEASE 159 72% 10% 126
2 SOST GENE 156 83% 7% 88
3 RECEPTOR RELATED PROTEIN 5 142 41% 22% 267
4 SOST 102 83% 5% 58
5 SERUM SCLEROSTIN 99 87% 4% 48
6 BMP ANTAGONIST 61 49% 7% 89
7 CIRCULATING SCLEROSTIN 50 84% 2% 27
8 LRP5 GENE 34 55% 3% 43
9 HIGH BONE MASS 33 55% 3% 42
10 SCLEROSTIN 30 38% 5% 62

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
WNT signaling in bone homeostasis and disease: from human mutations to treatments 2013 167 221 56%
Sclerostin: Current Knowledge and Future Perspectives 2010 118 58 79%
Update on Wnt signaling in bone cell biology and bone disease 2012 110 270 47%
Sclerostin and Dickkopf-1 as Therapeutic Targets in Bone Diseases 2012 73 211 55%
Involvement of WNT/beta-catenin Signaling in the Treatment of Osteoporosis 2013 24 88 73%
Regulation of bone mass by Wnt signaling 2006 522 88 41%
Anti-sclerostin antibodies: Utility in treatment of osteoporosis 2014 5 21 86%
Wnt signalling in osteoporosis: mechanisms and novel therapeutic approaches 2013 25 125 54%
Minireview: Targeting the Wnt/beta-catenin pathway to regulate bone formation in the adult skeleton 2007 225 82 41%
Wnt signaling in bone metabolism 2009 62 80 75%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 GENE FUNCT TARGET VALIDAT 5 63% 0.4% 5
2 MUSCULOSKELETAL DIS AREA 3 32% 0.6% 8
3 UMR 1132 3 40% 0.5% 6
4 CELL SIGNALING CARCINOGENESIS 2 20% 0.8% 10
5 ABS BIOMED SCI 2 67% 0.2% 2
6 COCA COLA ANTI AGING MED 2 67% 0.2% 2
7 IFIMAVRETICEF 2 50% 0.2% 3
8 EXCELLENCE OSTEOPOROSIS 2 40% 0.3% 4
9 HOSP U RIO HORTEGA 1 38% 0.2% 3
10 ENDOCRINOL METAB NUTR DIABET 1 50% 0.2% 2

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000197917 DKK 3//REIC//REIC DKK 3
2 0.0000128973 TERIPARATIDE//PTH//REG BONE
3 0.0000121765 BETA CATENIN//AXIN//WNT
4 0.0000115801 MOL STAT GENET//OSTEOPROTEGERIN GENE//OSTEOPOROSIS
5 0.0000115759 BARWON BIOMED//SEROTONIN 2B RECEPTOR//BONE QCT MICROCT
6 0.0000112038 OSTEOCYTE//OSTEOCYTES//BONE FLUID FLOW
7 0.0000103705 CLEIDOCRANIAL DYSPLASIA//RUNX2//OSTERIX
8 0.0000090421 ROR2//ROBINOW SYNDROME//WNT5A
9 0.0000086909 MIR 140//MICRORNA 140//MICRORNA TARGET IDENTIFICATION
10 0.0000073386 NORRIE DISEASE//FAMILIAL EXUDATIVE VITREORETINOPATHY//FRIZZLED 4