Class information for:
Level 1: ANTIGEN PROCESSING MACHINERY//BIOQUIM BIOL MOL INMUNOL 3//HLA CLASS I

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
7789 1248 38.2 79%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
151 22214 IMMUNOTHERAPY//DENDRITIC CELLS//CANCER IMMUNOLOGY IMMUNOTHERAPY

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 ANTIGEN PROCESSING MACHINERY Author keyword 20 66% 2% 19
2 BIOQUIM BIOL MOL INMUNOL 3 Address 12 54% 1% 15
3 HLA CLASS I Author keyword 9 15% 4% 54
4 HOSP UNIV VIRGEN DE LAS NIEVES Address 8 70% 1% 7
5 HOSP UNIV VIRGEN NIEVES Address 7 39% 1% 14
6 SERV ANAL CLIN INMUNOL Address 4 38% 1% 9
7 HLA CLASS I ANTIGEN Author keyword 4 40% 1% 8
8 ANAL CLIN INMUNOL Address 3 100% 0% 3
9 BIOQUIM BIOL MOL 3 INMUNOL Address 3 100% 0% 3
10 HLA LOSS Author keyword 3 100% 0% 3

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 ANTIGEN PROCESSING MACHINERY 20 66% 2% 19 Search ANTIGEN+PROCESSING+MACHINERY Search ANTIGEN+PROCESSING+MACHINERY
2 HLA CLASS I 9 15% 4% 54 Search HLA+CLASS+I Search HLA+CLASS+I
3 HLA CLASS I ANTIGEN 4 40% 1% 8 Search HLA+CLASS+I+ANTIGEN Search HLA+CLASS+I+ANTIGEN
4 HLA LOSS 3 100% 0% 3 Search HLA+LOSS Search HLA+LOSS
5 HUMAN LEUKOCYTE ANTIGEN CLASS I MOLECULE 3 100% 0% 3 Search HUMAN+LEUKOCYTE+ANTIGEN+CLASS+I+MOLECULE Search HUMAN+LEUKOCYTE+ANTIGEN+CLASS+I+MOLECULE
6 TRANSPORTER ASSOCIATED WITH ANTIGEN PROCESSING 1 3 60% 0% 3 Search TRANSPORTER+ASSOCIATED+WITH+ANTIGEN+PROCESSING+1 Search TRANSPORTER+ASSOCIATED+WITH+ANTIGEN+PROCESSING+1
7 HLA I 3 30% 1% 7 Search HLA+I Search HLA+I
8 TAP 1 2 38% 0% 5 Search TAP+1 Search TAP+1
9 NK CELL ACTIVATING LIGAND 2 67% 0% 2 Search NK+CELL+ACTIVATING+LIGAND Search NK+CELL+ACTIVATING+LIGAND
10 HUMAN LEUKOCYTE ANTIGEN CLASS I 2 21% 1% 9 Search HUMAN+LEUKOCYTE+ANTIGEN+CLASS+I Search HUMAN+LEUKOCYTE+ANTIGEN+CLASS+I

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 HAPLOTYPE LOSS 47 86% 2% 24
2 ALTERED PHENOTYPES 26 100% 1% 11
3 BETA 2 MICROGLOBULIN MESSENGER RNA 21 73% 1% 16
4 HLA HAPLOTYPE LOSS 21 85% 1% 11
5 INTRALOCUS DETERMINANT 18 89% 1% 8
6 CLASS I PHENOTYPES 11 57% 1% 13
7 COORDINATED DOWN REGULATION 11 78% 1% 7
8 MARKEDLY DECREASED EXPRESSION 9 83% 0% 5
9 ANTIGEN PROCESSING MACHINERY 7 25% 2% 26
10 B2M GENE 7 64% 1% 7

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
"Hard" and "soft" lesions underlying the HLA Class I alterations in cancer cells: implications for immunotherapy 2010 49 64 81%
MHC class I antigens, immune surveillance, and tumor immune escape 2003 189 72 65%
NATURAL-HISTORY OF HLA EXPRESSION DURING TUMOR-DEVELOPMENT 1993 320 55 65%
LOSS OF HLA CLASS-I ANTIGENS BY MELANOMA-CELLS - MOLECULAR MECHANISMS, FUNCTIONAL-SIGNIFICANCE AND CLINICAL RELEVANCE 1995 364 46 50%
Implications for immunosurveillance of altered HLA class I phenotypes in human tumours 1997 462 59 36%
MHC antigens and tumor escape from immune surveillance 2001 135 165 67%
Targeting HLA class I expression to increase tumor immunogenicity 2012 16 49 63%
MHC Class I Antigen Processing and Presenting Machinery: Organization, Function, and Defects in Tumor Cells 2013 13 197 35%
HLA class I antigen downregulation in human cancers: T-cell immunotherapy revives an old story 1999 171 46 50%
Novel insights into the molecular mechanisms of HLA class I abnormalities 2012 15 48 58%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 BIOQUIM BIOL MOL INMUNOL 3 12 54% 1.2% 15
2 HOSP UNIV VIRGEN DE LAS NIEVES 8 70% 0.6% 7
3 HOSP UNIV VIRGEN NIEVES 7 39% 1.1% 14
4 SERV ANAL CLIN INMUNOL 4 38% 0.7% 9
5 ANAL CLIN INMUNOL 3 100% 0.2% 3
6 BIOQUIM BIOL MOL 3 INMUNOL 3 100% 0.2% 3
7 HOSP VIRGEN NIEVES 3 22% 0.9% 11
8 SHIONOGI BIOMED S 2 67% 0.2% 2
9 BIOCHEM MOL BIOL IMMUNOL 3 2 40% 0.3% 4
10 CLIN ANAL IMMUNOL 2 43% 0.2% 3

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000132234 TUMOR INFILTRATING LYMPHOCYTES//ADOPTIVE IMMUNOTHERAPY//AUTOLYMPHOCYTE THERAPY
2 0.0000115734 INTERDISCIPLINARY STUDIES SECT//BIOL SCI TUNIS//BLOOD TRANSFUS 1
3 0.0000112524 PED GENE//QA 2//CLASS IB
4 0.0000106999 TAPASIN//TRANSPORTER ASSOCIATED WITH ANTIGEN PROCESSING//PEPTIDE LOADING COMPLEX
5 0.0000102756 POLYVALENT ANTIGEN//AUTOLOGOUS ANTIBODY//B700
6 0.0000097891 ADV CELL MOL THER Y//SHUNDE PEOPLES HOSP//TUMOR VACCINE
7 0.0000082398 UROONCOL PROGRAM//SERUM BETA2 MICROGLOBULIN//MOL UROL THER EUT PROGRAM
8 0.0000077687 CIITA//BARE LYMPHOCYTE SYNDROME//CLASS II TRANSACTIVATOR
9 0.0000077271 CANCER TESTIS ANTIGEN//CANCER TESTIS ANTIGENS//NY ESO 1
10 0.0000072721 TUMOR BEARING STATE//AUTOIMMUNOTHERAPY//CD8 CELL REACTIVITY