Class information for:
Level 1: INSULIN DEGRADING ENZYME//NEPRILYSIN//INSULYSIN

Basic class information
ID Publications Average number
of references		 Avg. shr. active
ref. in WoS
7147 1323 39.1 66%


Bar chart of Publication_year

Last years might be incomplete

Classes in level above (level 2)


ID, lev.
above		 Publications Label for level above
1399 7604 INSULIN DEGRADING ENZYME//GLYCOSYLPHOSPHATIDYLINOSITOL//NEPRILYSIN

Terms with highest relevance score


Rank Term Type of term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 INSULIN DEGRADING ENZYME Author keyword 88 59% 7% 98
2 NEPRILYSIN Author keyword 49 36% 8% 109
3 INSULYSIN Author keyword 17 72% 1% 13
4 INSULIN DEGRADATION Author keyword 11 54% 1% 14
5 IDE Author keyword 6 20% 2% 26
6 A BETA DEGRADING ENZYMES Author keyword 6 100% 0% 4
7 NEP2 Author keyword 6 100% 0% 4
8 PITRILYSIN Author keyword 6 100% 0% 4
9 A BETA METABOLISM Author keyword 4 75% 0% 3
10 INSULINASE Author keyword 4 75% 0% 3

Web of Science journal categories

Author Key Words


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class		 LCSH search Wikipedia search
1 INSULIN DEGRADING ENZYME 88 59% 7% 98 Search INSULIN+DEGRADING+ENZYME Search INSULIN+DEGRADING+ENZYME
2 NEPRILYSIN 49 36% 8% 109 Search NEPRILYSIN Search NEPRILYSIN
3 INSULYSIN 17 72% 1% 13 Search INSULYSIN Search INSULYSIN
4 INSULIN DEGRADATION 11 54% 1% 14 Search INSULIN+DEGRADATION Search INSULIN+DEGRADATION
5 IDE 6 20% 2% 26 Search IDE Search IDE
6 A BETA DEGRADING ENZYMES 6 100% 0% 4 Search A+BETA+DEGRADING+ENZYMES Search A+BETA+DEGRADING+ENZYMES
7 NEP2 6 100% 0% 4 Search NEP2 Search NEP2
8 PITRILYSIN 6 100% 0% 4 Search PITRILYSIN Search PITRILYSIN
9 A BETA METABOLISM 4 75% 0% 3 Search A+BETA+METABOLISM Search A+BETA+METABOLISM
10 INSULINASE 4 75% 0% 3 Search INSULINASE Search INSULINASE

Key Words Plus


Rank Web of Science journal category Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 INSULIN DEGRADING ENZYME 36 24% 10% 131
2 INSULYSIN 34 93% 1% 13
3 METALLOENDOPROTEASE INHIBITORS 34 93% 1% 13
4 CYTOSOLIC PROTEOLYTIC COMPLEX 31 92% 1% 12
5 LOW DENSITY VESICLES 23 100% 1% 10
6 BLOCK SPANNING IDE 17 68% 1% 15
7 PROTEASE III 17 63% 1% 17
8 ARGININE DIBASIC CONVERTASE 16 56% 2% 20
9 NRD CONVERTASE 15 68% 1% 13
10 NEPRILYSIN 15 28% 3% 45

Journals

Reviews


Title Publ. year Cit. Active references % act. ref.
to same field
Insulin-degrading enzyme 1996 109 52 83%
Insulin-Degrading Enzyme: Structure-Function Relationship and its Possible Roles in Health and Disease 2009 39 106 71%
Insulin degradation: Progress and potential 1998 348 208 71%
Are amyloid-degrading enzymes viable therapeutic targets in Alzheimer's disease? 2012 48 203 32%
A beta-degrading enzymes in Alzheimer's disease 2008 151 161 35%
Insulin, insulin-degrading enzyme and amyloid-beta peptide in Alzheimer's disease: review and hypothesis 2006 201 89 45%
A beta-Degrading Enzymes: Potential for Treatment of Alzheimer Disease 2011 56 266 34%
Clearing the brain's amyloid cobwebs 2001 331 22 50%
INSULIN DEGRADATION - MECHANISMS, PRODUCTS, AND SIGNIFICANCE 1988 242 285 47%
Amyloid beta-degrading cryptidases: insulin degrading enzyme, presequence peptidase, and neprilysin 2008 63 87 47%

Address terms


Rank Address term Relevance score
(tfidf)		 Class's shr.
of term's tot.
occurrences		 Shr. of publ.
in class containing
term		 Num. of
publ. in
class
1 PROTEOLYT NEUROSCI 4 16% 1.8% 24
2 PATHOL NEUROPATHOL NEUROSCI 2 67% 0.2% 2
3 PROTE INFORMAT SERV IL 2 43% 0.2% 3
4 U510 1 21% 0.5% 6
5 BIOL SCI BIOTECHNOL MED 1 50% 0.2% 2
6 CATEDRA QUIM BIOL PATOL 1 50% 0.2% 2
7 HTAL NINOS R GUTIERREZ 1 100% 0.2% 2
8 MED NEPHROL SERV 1 50% 0.2% 2
9 NEURODEGENERAT DIS GENE DISCOVERY 1 100% 0.2% 2
10 STRUCT BIOINFORMAT UNIT 1 22% 0.4% 5

Related classes at same level (level 1)


Rank Relatedness score Related classes
1 0.0000133182 LEPRECHAUNISM//INSULIN RECEPTOR//DONOHUE SYNDROME
2 0.0000129474 PLACENTAL INSULIN RECEPTORS//DIABET BRANCH BLDG 10 ROOM 8 S 243//HLTH SCI BIOMATH
3 0.0000112943 CYCLIC AMP ANTAGONIST//CYCLIC PIP//SCI PEDIAT ADOLESCENZA
4 0.0000087023 ENDOTHELIN CONVERTING ENZYME//PHOSPHORAMIDON//BIG ENDOTHELIN
5 0.0000077397 INTERMEDIARY METABOLISM ENZYMES//NEUROSCI DOCTORAL SUBPROGRAM//AURON MISHEIL THERAPY
6 0.0000073918 ALPHA 1 ANTICHYMOTRYPSIN//D10S1423//PSYCHIATGERONTOL UNIT
7 0.0000071607 GLUCAGON RECEPTOR//GLUCAGON RECEPTOR GENE//GLUCAGON ANTAGONIST
8 0.0000058815 ASIALOGLYCOPROTEIN RECEPTOR//LIVER TARGETING OF DRUGS//LACTOSAMINATED POLY L LYSINE
9 0.0000057921 GRP GROWTH TORS VERTEBRATE DEV//BALANCO HIDRO SALINO NUCL MED CIRURGIA EXPT//BRAIN INSULIN RECEPTORS
10 0.0000050699 FAMILIAL DANISH DEMENTIA//BRI2//GLUTAMINYL CYCLASE